{"id":"https://openalex.org/W3127021983","doi":"https://doi.org/10.1038/s41565-020-00843-7","title":"Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection","display_name":"Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection","publication_year":2021,"publication_date":"2021-02-01","ids":{"openalex":"https://openalex.org/W3127021983","doi":"https://doi.org/10.1038/s41565-020-00843-7","mag":"3127021983","pmid":"https://pubmed.ncbi.nlm.nih.gov/33526838"},"language":"en","primary_location":{"id":"doi:10.1038/s41565-020-00843-7","doi":"https://doi.org/10.1038/s41565-020-00843-7","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41565-020-00843-7","pdf_url":null,"source":{"id":"https://openalex.org/S7822423","display_name":"Nature Nanotechnology","issn_l":"1748-3387","issn":["1748-3387","1748-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Nanotechnology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100345396","display_name":"Jing Zhang","orcid":"https://orcid.org/0000-0002-4825-9674","observed_orcids":["https://orcid.org/0000-0002-4825-9674"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zhang","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chen Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Chen","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018230988","display_name":"Anning Li","orcid":"https://orcid.org/0000-0001-7695-161X","observed_orcids":["https://orcid.org/0000-0001-7695-161X"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210161528","display_name":"Qilu Hospital of Shandong University","ror":"https://ror.org/056ef9489","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161528"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anning Li","raw_affiliation_strings":["Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210161528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039184817","display_name":"Weiqiang Jing","orcid":"https://orcid.org/0000-0003-3049-2846","observed_orcids":["https://orcid.org/0000-0003-3049-2846","https://orcid.org/0009-0006-1263-2760"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210161528","display_name":"Qilu Hospital of Shandong University","ror":"https://ror.org/056ef9489","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161528"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiqiang Jing","raw_affiliation_strings":["Department of Urology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210161528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088340227","display_name":"Peng Sun","orcid":"https://orcid.org/0000-0003-4117-4165","observed_orcids":["https://orcid.org/0000-0003-4117-4165"]},"institutions":[{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Sun","raw_affiliation_strings":["Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I134738993"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xueyang Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueyang Huang","raw_affiliation_strings":["Department of Cell Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province, P. R. China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053146492","display_name":"Yingchao Liu","orcid":"https://orcid.org/0000-0002-6656-2511","observed_orcids":["https://orcid.org/0000-0002-6656-2511"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210116517","display_name":"Shandong Provincial Hospital","ror":"https://ror.org/02ar2nf05","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116517"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingchao Liu","raw_affiliation_strings":["Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, P. R. China","Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I4210116517","https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shengchang Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengchang Zhang","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101899863","display_name":"Wei Du","orcid":"https://orcid.org/0000-0001-8271-6704","observed_orcids":["https://orcid.org/0000-0001-8271-6704"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Du","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109442507","display_name":"Rui Zhang","orcid":"https://orcid.org/0009-0000-2138-2456","observed_orcids":["https://orcid.org/0009-0000-2138-2456"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Zhang","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101762743","display_name":"Ying Liu","orcid":"https://orcid.org/0000-0002-3328-026X","observed_orcids":["https://orcid.org/0000-0002-3328-026X"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210116517","display_name":"Shandong Provincial Hospital","ror":"https://ror.org/02ar2nf05","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116517"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Liu","raw_affiliation_strings":["Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, P. R. China","Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I4210116517","https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075219319","display_name":"Aihua Gong","orcid":"https://orcid.org/0000-0001-8803-4595","observed_orcids":["https://orcid.org/0000-0001-8803-4595","https://orcid.org/0000-0002-8778-1297"]},"institutions":[{"id":"https://openalex.org/I115592961","display_name":"Jiangsu University","ror":"https://ror.org/03jc41j30","country_code":"CN","type":"education","lineage":["https://openalex.org/I115592961"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Aihua Gong","raw_affiliation_strings":["Department of Cell Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province, P. R. China","institution_ids":["https://openalex.org/I115592961"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101957070","display_name":"Jibiao Wu","orcid":"https://orcid.org/0000-0002-1977-4335","observed_orcids":["https://orcid.org/0000-0002-1977-4335"]},"institutions":[{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jibiao Wu","raw_affiliation_strings":["Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I134738993"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090123727","display_name":"Xinyi Jiang","orcid":"https://orcid.org/0000-0003-0074-6876","observed_orcids":["https://orcid.org/0000-0003-0074-6876","https://orcid.org/0000-0003-4447-9693"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xinyi Jiang","raw_affiliation_strings":["Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China. xinyijiang@sdu.edu.cn","Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China"],"raw_orcid":"https://orcid.org/0000-0003-0074-6876","affiliations":[{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China. xinyijiang@sdu.edu.cn","institution_ids":["https://openalex.org/I154099455"]},{"raw_affiliation_string":"Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, P. R. China","institution_ids":["https://openalex.org/I154099455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5090123727"],"corresponding_institution_ids":["https://openalex.org/I154099455"],"apc_list":{"value":11390,"currency":"USD","value_usd":11390},"apc_paid":null,"fwci":31.4395,"has_fulltext":false,"cited_by_count":305,"citation_normalized_percentile":{"value":0.99859089,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"16","issue":"5","first_page":"538","last_page":"548"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.021299999207258224,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hydrogels","display_name":"hydrogels","score":0.6269999742507935},{"id":"https://openalex.org/keywords/immunostimulants","display_name":"immunostimulants","score":0.7049999833106995},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.8859999775886536},{"id":"https://openalex.org/keywords/surgical-resection","display_name":"surgical resection","score":0.7170000076293945},{"id":"https://openalex.org/keywords/immunogenic-cell-death","display_name":"immunogenic cell death","score":0.9800000190734863},{"id":"https://openalex.org/keywords/ido1","display_name":"IDO1","score":0.9769999980926514},{"id":"https://openalex.org/keywords/t-cell-infiltration","display_name":"T cell infiltration","score":0.8600000143051147},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.7390000224113464},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C2781264782","wikidata":"https://www.wikidata.org/wiki/Q901656","display_name":"Immunostimulant","level":3,"score":0.7527815103530884},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.638303279876709},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4171587824821472},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3496682643890381},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30966800451278687},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17320188879966736},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.15893062949180603}],"mesh":[{"descriptor_ui":"D000074322","descriptor_name":"Antineoplastic Agents, Immunological","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000074322","descriptor_name":"Antineoplastic Agents, Immunological","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000079527","descriptor_name":"Immunogenic Cell Death","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D050997","descriptor_name":"Nanomedicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D054357","descriptor_name":"Chemokine CXCL10","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/s41565-020-00843-7","doi":"https://doi.org/10.1038/s41565-020-00843-7","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41565-020-00843-7","pdf_url":null,"source":{"id":"https://openalex.org/S7822423","display_name":"Nature Nanotechnology","issn_l":"1748-3387","issn":["1748-3387","1748-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Nanotechnology","raw_type":"journal-article"},{"id":"pmid:33526838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33526838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature nanotechnology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2432506324","display_name":null,"funder_award_id":"2019JZZY021013","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"},{"id":"https://openalex.org/G2633834330","display_name":null,"funder_award_id":"2020QNQT003","funder_id":"https://openalex.org/F4320311026","funder_display_name":"Shandong University"},{"id":"https://openalex.org/G7916350479","display_name":null,"funder_award_id":"81874419","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8517646404","display_name":null,"funder_award_id":"2019GSF108080","funder_id":"https://openalex.org/F4320313895","funder_display_name":"Department of Science and Technology of Shandong Province"}],"funders":[{"id":"https://openalex.org/F4320311026","display_name":"Shandong University","ror":"https://ror.org/0207yh398"},{"id":"https://openalex.org/F4320313895","display_name":"Department of Science and Technology of Shandong Province","ror":"https://ror.org/01b9fvd84"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1588685142","https://openalex.org/W1982488143","https://openalex.org/W2016612145","https://openalex.org/W2042699075","https://openalex.org/W2055348159","https://openalex.org/W2064214863","https://openalex.org/W2067632426","https://openalex.org/W2068069968","https://openalex.org/W2072984130","https://openalex.org/W2073586533","https://openalex.org/W2090410108","https://openalex.org/W2092235636","https://openalex.org/W2096287682","https://openalex.org/W2108971625","https://openalex.org/W2123363005","https://openalex.org/W2124736921","https://openalex.org/W2130511906","https://openalex.org/W2208284809","https://openalex.org/W2418297050","https://openalex.org/W2440836370","https://openalex.org/W2507880739","https://openalex.org/W2555969202","https://openalex.org/W2563647161","https://openalex.org/W2595863515","https://openalex.org/W2596261790","https://openalex.org/W2769842281","https://openalex.org/W2770893462","https://openalex.org/W2791364631","https://openalex.org/W2796584001","https://openalex.org/W2887361912","https://openalex.org/W2924637436","https://openalex.org/W2994525341","https://openalex.org/W2997600806","https://openalex.org/W3000438116"],"related_works":["https://openalex.org/W4286008283","https://openalex.org/W7118434012","https://openalex.org/W3213026656","https://openalex.org/W7154091623","https://openalex.org/W4362457740","https://openalex.org/W4397032465","https://openalex.org/W2883186016","https://openalex.org/W4289638094","https://openalex.org/W7219904514","https://openalex.org/W4405758071"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":41},{"year":2025,"cited_by_count":40},{"year":2024,"cited_by_count":69},{"year":2023,"cited_by_count":79},{"year":2022,"cited_by_count":60},{"year":2021,"cited_by_count":16}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-02-15T00:00:00"}