{"id":"https://openalex.org/W3126656944","doi":"https://doi.org/10.1136/bmjopen-2020-044054","title":"Cost-effectiveness analysis of percutaneous coronary intervention for single-vessel coronary artery disease: an economic evaluation of the ORBITA trial","display_name":"Cost-effectiveness analysis of percutaneous coronary intervention for single-vessel coronary artery disease: an economic evaluation of the ORBITA trial","publication_year":2021,"publication_date":"2021-02-01","ids":{"openalex":"https://openalex.org/W3126656944","doi":"https://doi.org/10.1136/bmjopen-2020-044054","mag":"3126656944","pmid":"https://pubmed.ncbi.nlm.nih.gov/33563623","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7875263"},"language":"en","primary_location":{"id":"doi:10.1136/bmjopen-2020-044054","doi":"https://doi.org/10.1136/bmjopen-2020-044054","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2020-044054","pdf_url":"https://bmjopen.bmj.com/content/bmjopen/11/2/e044054.full.pdf","source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmjopen.bmj.com/content/bmjopen/11/2/e044054.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052741381","display_name":"Victoria McCreanor","orcid":"https://orcid.org/0000-0002-0589-8521","observed_orcids":["https://orcid.org/0000-0002-0589-8521"]},"institutions":[{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]},{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]},{"id":"https://openalex.org/I4405269172","display_name":"Metro North Hospital and Health Service","ror":"https://ror.org/03a0hqz22","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4405269172"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Victoria McCreanor","raw_affiliation_strings":["Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia","Jamieson Trauma Institute, Royal Brisbane and Women\u2019s Hospital, Metro North Hospital and Health Service, Herston, Queensland, Australia"],"raw_orcid":"https://orcid.org/0000-0002-0589-8521","affiliations":[{"raw_affiliation_string":"Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I160993911"]},{"raw_affiliation_string":"Jamieson Trauma Institute, Royal Brisbane and Women\u2019s Hospital, Metro North Hospital and Health Service, Herston, Queensland, Australia","institution_ids":["https://openalex.org/I2799393793","https://openalex.org/I4405269172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013665231","display_name":"Alexandra N. Nowbar","orcid":"https://orcid.org/0000-0001-7567-5975","observed_orcids":["https://orcid.org/0000-0001-7567-5975"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexandra Nowbar","raw_affiliation_strings":["Imperial College Healthcare NHS Trust, London, UK","National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0001-7567-5975","affiliations":[{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006874125","display_name":"Christopher Rajkumar","orcid":"https://orcid.org/0000-0002-0086-1113","observed_orcids":["https://orcid.org/0000-0002-0086-1113"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher Rajkumar","raw_affiliation_strings":["Imperial College Healthcare NHS Trust, London, UK","National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055115361","display_name":"Adrian Gerard Barnett","orcid":"https://orcid.org/0000-0001-6339-0374","observed_orcids":["https://orcid.org/0000-0001-6339-0374"]},"institutions":[{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Adrian G Barnett","raw_affiliation_strings":["Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia"],"raw_orcid":"https://orcid.org/0000-0001-6339-0374","affiliations":[{"raw_affiliation_string":"Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I160993911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086241929","display_name":"D\u00e1rrel P. Francis","orcid":"https://orcid.org/0000-0002-3410-0814","observed_orcids":["https://orcid.org/0000-0002-3410-0814"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Darrel Francis","raw_affiliation_strings":["Imperial College Healthcare NHS Trust, London, UK","National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078236989","display_name":"Nicholas Graves","orcid":"https://orcid.org/0000-0002-5559-3267","observed_orcids":["https://orcid.org/0000-0002-5559-3267"]},"institutions":[{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Nicholas Graves","raw_affiliation_strings":["Health Services and Systems Research, Duke-NUS Medical School, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Services and Systems Research, Duke-NUS Medical School, Singapore","institution_ids":["https://openalex.org/I4210126319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069006768","display_name":"William E. Boden","orcid":"https://orcid.org/0000-0001-7145-8084","observed_orcids":["https://orcid.org/0000-0001-7145-8084"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801671727","display_name":"VA Boston Healthcare System","ror":"https://ror.org/04v00sg98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801671727","https://openalex.org/I4210095851"]},{"id":"https://openalex.org/I4210095851","display_name":"VA New England Healthcare System","ror":"https://ror.org/00s61s029","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210095851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William E Boden","raw_affiliation_strings":["Boston University School of Medicine, Boston, Massachusetts, USA","Harvard Medical School, Boston, Massachusetts, USA","VA New England Healthcare System, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston University School of Medicine, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"VA New England Healthcare System, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I2801671727","https://openalex.org/I4210095851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052993534","display_name":"William S. Weintraub","orcid":"https://orcid.org/0000-0002-5384-5571","observed_orcids":["https://orcid.org/0000-0002-5384-5571"]},"institutions":[{"id":"https://openalex.org/I1285739803","display_name":"MedStar Washington Hospital Center","ror":"https://ror.org/05ry42w04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285739803","https://openalex.org/I86755215"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William S Weintraub","raw_affiliation_strings":["Georgetown University, Washington, District of Columbia, USA","MedStar Washington Hospital Center, Washington, District of Columbia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgetown University, Washington, District of Columbia, USA","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"MedStar Washington Hospital Center, Washington, District of Columbia, USA","institution_ids":["https://openalex.org/I1285739803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002322573","display_name":"Rasha Kadem Al-Lamee","orcid":"https://orcid.org/0000-0003-3752-5532","observed_orcids":["https://orcid.org/0000-0003-3752-5532"]},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rasha Al-Lamee","raw_affiliation_strings":["Imperial College Healthcare NHS Trust, London, UK","National Heart and Lung Institute, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial College Healthcare NHS Trust, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006265756","display_name":"William Anthony Parsonage","orcid":"https://orcid.org/0000-0002-0223-5378","observed_orcids":["https://orcid.org/0000-0002-0223-5378"]},"institutions":[{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]},{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"William A Parsonage","raw_affiliation_strings":["Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia","Cardiology, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia"],"raw_orcid":"https://orcid.org/0000-0002-0223-5378","affiliations":[{"raw_affiliation_string":"Australian Centre for Health Services Innovation (AusHSI) and Centre for Healthcare Transformation, Queensland University of Technology (QUT), Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I160993911"]},{"raw_affiliation_string":"Cardiology, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia","institution_ids":["https://openalex.org/I2799393793"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5006265756"],"corresponding_institution_ids":["https://openalex.org/I160993911","https://openalex.org/I2799393793"],"apc_list":{"value":1500,"currency":"GBP","value_usd":1839},"apc_paid":{"value":1500,"currency":"GBP","value_usd":1839},"fwci":2.5823,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.89398633,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":98},"biblio":{"volume":"11","issue":"2","first_page":"e044054","last_page":"e044054"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.7519999742507935,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.7519999742507935,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.24570000171661377,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.9919999837875366},{"id":"https://openalex.org/keywords/single-vessel-coronary-artery-disease","display_name":"single-vessel coronary artery disease","score":0.9909999966621399},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.9750000238418579},{"id":"https://openalex.org/keywords/refractory-angina","display_name":"refractory angina","score":0.8820000290870667},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.9190000295639038},{"id":"https://openalex.org/keywords/orbita-trial","display_name":"ORBITA trial","score":0.8870000243186951},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.8289999961853027},{"id":"https://openalex.org/keywords/antianginal-therapy","display_name":"antianginal therapy","score":0.699999988079071},{"id":"https://openalex.org/keywords/markov-model","display_name":"Markov model","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9620214104652405},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.8120832443237305},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.6946769952774048},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.6705941557884216},{"id":"https://openalex.org/C2778425758","wikidata":"https://www.wikidata.org/wiki/Q180762","display_name":"Angina","level":3,"score":0.6609532833099365},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5457351803779602},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.5104993581771851},{"id":"https://openalex.org/C64332521","wikidata":"https://www.wikidata.org/wiki/Q614165","display_name":"Quality-adjusted life year","level":3,"score":0.49265915155410767},{"id":"https://openalex.org/C2780326628","wikidata":"https://www.wikidata.org/wiki/Q539795","display_name":"Angioplasty","level":2,"score":0.44550621509552},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4289226233959198},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4136312007904053},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.34002578258514404},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.09727910161018372},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013222","descriptor_name":"State Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019057","descriptor_name":"Quality-Adjusted Life Years","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060050","descriptor_name":"Angina, Stable","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1136/bmjopen-2020-044054","doi":"https://doi.org/10.1136/bmjopen-2020-044054","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2020-044054","pdf_url":"https://bmjopen.bmj.com/content/bmjopen/11/2/e044054.full.pdf","source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7875263","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7875263","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"Text"},{"id":"pmid:33563623","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33563623","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ open","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.qut.edu.au:208196","doi":null,"is_oa":true,"landing_page_url":"https://eprints.qut.edu.au/208196/1/75478867.pdf","pdf_url":"https://eprints.qut.edu.au/208196/1/75478867.pdf","source":{"id":"https://openalex.org/S4306402607","display_name":"QUT ePrints (Queensland University of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I160993911","host_organization_name":"Queensland University of Technology","host_organization_lineage":["https://openalex.org/I160993911"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMJ Open","raw_type":"Contribution to Journal"},{"id":"pmh:oai:doaj.org/article:e82722a0f07341758a72010e93e81963","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e82722a0f07341758a72010e93e81963","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMJ Open, Vol 11, Iss 2 (2021)","raw_type":"article"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/87170","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/87170","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"8","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1136/bmjopen-2020-044054","doi":"https://doi.org/10.1136/bmjopen-2020-044054","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2020-044054","pdf_url":"https://bmjopen.bmj.com/content/bmjopen/11/2/e044054.full.pdf","source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G341442039","display_name":"Is there a difference between clinical angina and experimentally inducible angina? A placebo-controlled experiment in stable coronary artery disease","funder_award_id":"MR/S021108/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5020491150","display_name":null,"funder_award_id":"P74227","funder_id":"https://openalex.org/F4320336039","funder_display_name":"NIHR Imperial Biomedical Research Centre"},{"id":"https://openalex.org/G6302509009","display_name":"Effect of antianginals on patient-reported outcomes and tests of ischaemia in stable coronary artery disease","funder_award_id":"NIHR300166","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320336039","display_name":"NIHR Imperial Biomedical Research Centre","ror":"https://ror.org/01kmhx639"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3126656944.pdf","grobid_xml":"https://content.openalex.org/works/W3126656944.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1936833235","https://openalex.org/W2010913334","https://openalex.org/W2012103753","https://openalex.org/W2124659021","https://openalex.org/W2133924558","https://openalex.org/W2160414137","https://openalex.org/W2166351234","https://openalex.org/W2343426002","https://openalex.org/W2516998275","https://openalex.org/W2582743722","https://openalex.org/W2766491028","https://openalex.org/W2969151610","https://openalex.org/W3014025744","https://openalex.org/W3088784487","https://openalex.org/W3122491543","https://openalex.org/W4231358771","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W3102848303","https://openalex.org/W2899550178","https://openalex.org/W2134096980","https://openalex.org/W7095165378","https://openalex.org/W2605240239","https://openalex.org/W2106788703","https://openalex.org/W2141266596","https://openalex.org/W155070914","https://openalex.org/W2380910036","https://openalex.org/W2146665164"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"the":[3,60,65,102,116,129,142],"cost-effectiveness":[4,27,209],"of":[5,74,85,118,133,144,188,190],"percutaneous":[6],"coronary":[7,17,175,249],"intervention":[8],"(PCI)":[9],"compared":[10,222,236],"with":[11,15,31,70,168,223,237,264],"placebo":[12,149,204,238],"in":[13,42,76,137,239],"patients":[14,138,145,167,184,240],"single-vessel":[16,174,248],"artery":[18,176,250],"disease":[19,177],"and":[20,80,87,98,141,171],"angina":[21,78,155,170,194,245],"despite":[22],"anti-anginal":[23,179],"therapy.":[24,180],"DESIGN:":[25],"A":[26,33],"analysis":[28,111],"comparing":[29],"PCI":[30,151,201,221,235],"placebo.":[32,224],"Markov":[34],"model":[35],"was":[36,112],"used":[37],"to":[38,59,114,120,127,150,153,200,247],"measure":[39],"incremental":[40],"cost-effectiveness,":[41],"cost":[43,214],"per":[44,217],"quality-adjusted":[45],"life-years":[46],"(QALYs)":[47],"gained,":[48],"over":[49,147],"12":[50,157],"months.":[51,158],"Health":[52,104],"utility":[53],"weights":[54],"were":[55,90,125,198,253],"estimated":[56,227],"using":[57,234],"responses":[58],"EuroQol":[61],"5-level":[62],"questionnaire,":[63],"from":[64,92,101,148],"Objective":[66],"Randomised":[67],"Blinded":[68],"Investigation":[69],"optimal":[71],"medical":[72,191,242],"Therapy":[73],"Angioplasty":[75],"stable":[77,169],"trial":[79],"UK":[81,161],"preference":[82],"weights.":[83],"Costs":[84],"procedures":[86],"follow-up":[88],"consultations":[89],"derived":[91],"Healthcare":[93],"Resource":[94],"Group":[95],"reference":[96],"costs":[97,100,136],"drug":[99,107],"National":[103],"Service":[105],"(NHS)":[106],"tariff.":[108],"Probabilistic":[109],"sensitivity":[110,256],"undertaken":[113],"test":[115,128],"robustness":[117],"results":[119,132],"parameter":[121],"uncertainty.":[122],"Scenario":[123],"analyses":[124],"performed":[126],"effect":[130,143],"on":[131,178],"reduced":[134],"pharmaceutical":[135],"undergoing":[139],"PCI,":[140],"crossing":[146],"due":[152,246],"refractory":[154],"within":[156],"SETTING:":[159],"Five":[160],"NHS":[162],"hospitals.":[163],"PARTICIPANTS:":[164],"200":[165],"adult":[166],"angiographically":[172],"severe":[173],"INTERVENTIONS:":[181],"At":[182],"recruitment,":[183],"received":[185],"6":[186],"weeks":[187],"optimisation":[189],"therapy":[192],"for":[193,220,244],"after":[195],"which":[196],"they":[197],"randomised":[199],"or":[202],"a":[203],"procedure.":[205],"OUTCOME":[206],"MEASURES:":[207],"Incremental":[208],"ratio":[210],"(ICER)":[211],"expressed":[212],"as":[213],"(in":[215],"\u00a3)":[216],"QALY":[218],"gained":[219,232],"RESULTS:":[225],"The":[226,259],"ICER":[228],"is":[229,262],"\u00a390":[230],"218/QALY":[231],"when":[233],"receiving":[241],"treatment":[243],"disease.":[251],"Results":[252],"robust":[254],"under":[255],"analyses.":[257],"CONCLUSIONS:":[258],"ORBITA":[260],"study":[261],"registered":[263],"ClinicalTrials.gov,":[265],"number":[266],"NCT02062593.":[267]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2021-02-15T00:00:00"}
