{"id":"https://openalex.org/W3125975673","doi":"https://doi.org/10.1007/s11033-021-06162-x","title":"Loss of Dec1 prevents autophagy in inflamed periodontal ligament fibroblast","display_name":"Loss of Dec1 prevents autophagy in inflamed periodontal ligament fibroblast","publication_year":2021,"publication_date":"2021-01-28","ids":{"openalex":"https://openalex.org/W3125975673","doi":"https://doi.org/10.1007/s11033-021-06162-x","mag":"3125975673","pmid":"https://pubmed.ncbi.nlm.nih.gov/33507476"},"language":"en","primary_location":{"id":"doi:10.1007/s11033-021-06162-x","doi":"https://doi.org/10.1007/s11033-021-06162-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11033-021-06162-x","pdf_url":null,"source":{"id":"https://openalex.org/S197962172","display_name":"Molecular Biology Reports","issn_l":"0301-4851","issn":["0301-4851","1573-4978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102349724","display_name":"Shunichi Oka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104946051","display_name":"Nihon University","ror":"https://ror.org/05jk51a88","country_code":"JP","type":"education","lineage":["https://openalex.org/I104946051"]},{"id":"https://openalex.org/I4405286816","display_name":"Dental Research Center, School of Dentistry, Nihon University","ror":"https://ror.org/0362w2x54","country_code":"JP","type":"facility","lineage":["https://openalex.org/I104946051","https://openalex.org/I4405286816"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunichi Oka","raw_affiliation_strings":["Department of Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan","Division of Immunology and Pathology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan","institution_ids":["https://openalex.org/I104946051"]},{"raw_affiliation_string":"Division of Immunology and Pathology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan","institution_ids":["https://openalex.org/I104946051","https://openalex.org/I4405286816"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaoyan Li","orcid":"https://orcid.org/0000-0002-3746-009X","observed_orcids":["https://orcid.org/0000-0002-3746-009X"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoyan Li","raw_affiliation_strings":["Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China. chocolate_yan@yeah.net","Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China"],"raw_orcid":"https://orcid.org/0000-0002-3746-009X","affiliations":[{"raw_affiliation_string":"Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China. chocolate_yan@yeah.net","institution_ids":["https://openalex.org/I183519381"]},{"raw_affiliation_string":"Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076571329","display_name":"Fengzhu Zhang","orcid":"https://orcid.org/0000-0003-0516-4314","observed_orcids":["https://orcid.org/0000-0003-0516-4314"]},"institutions":[{"id":"https://openalex.org/I104946051","display_name":"Nihon University","ror":"https://ror.org/05jk51a88","country_code":"JP","type":"education","lineage":["https://openalex.org/I104946051"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Fengzhu Zhang","raw_affiliation_strings":["Department of Anesthesiology, Nihon University School of Dentistry At Matsudo, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Nihon University School of Dentistry At Matsudo, Chiba, Japan","institution_ids":["https://openalex.org/I104946051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071364463","display_name":"Nitesh Tewari","orcid":"https://orcid.org/0000-0002-6747-5110","observed_orcids":["https://orcid.org/0000-0002-6747-5110"]},"institutions":[{"id":"https://openalex.org/I63739035","display_name":"All India Institute of Medical Sciences","ror":"https://ror.org/02dwcqs71","country_code":"IN","type":"education","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I63739035"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nitesh Tewari","raw_affiliation_strings":["Division of Pedodontics and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pedodontics and Preventive Dentistry, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India","institution_ids":["https://openalex.org/I63739035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029718121","display_name":"Il-Shin Kim","orcid":"https://orcid.org/0000-0001-7149-7016","observed_orcids":["https://orcid.org/0000-0001-7149-7016"]},"institutions":[{"id":"https://openalex.org/I195373058","display_name":"Honam University","ror":"https://ror.org/04vj5r404","country_code":"KR","type":"education","lineage":["https://openalex.org/I195373058"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Il-Shin Kim","raw_affiliation_strings":["Department of Dental Hygiene, Honam University, Gwangju, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Hygiene, Honam University, Gwangju, Republic of Korea","institution_ids":["https://openalex.org/I195373058"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101879518","display_name":"Chongchong Chen","orcid":"https://orcid.org/0000-0001-7572-7819","observed_orcids":["https://orcid.org/0000-0001-7572-7819"]},"institutions":[{"id":"https://openalex.org/I163151501","display_name":"Hangzhou Normal University","ror":"https://ror.org/014v1mr15","country_code":"CN","type":"education","lineage":["https://openalex.org/I163151501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chongchong Chen","raw_affiliation_strings":["Department of Stomatology, Hangzhou Normal University, Hangzhou, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stomatology, Hangzhou Normal University, Hangzhou, People's Republic of China","institution_ids":["https://openalex.org/I163151501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100376838","display_name":"Liangjun Zhong","orcid":"https://orcid.org/0000-0001-6225-4784","observed_orcids":["https://orcid.org/0000-0001-6225-4784"]},"institutions":[{"id":"https://openalex.org/I163151501","display_name":"Hangzhou Normal University","ror":"https://ror.org/014v1mr15","country_code":"CN","type":"education","lineage":["https://openalex.org/I163151501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liangjun Zhong","raw_affiliation_strings":["Department of Stomatology, Hangzhou Normal University, Hangzhou, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stomatology, Hangzhou Normal University, Hangzhou, People's Republic of China","institution_ids":["https://openalex.org/I163151501"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102281075","display_name":"Nobushiro Hamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47951555","display_name":"Kanagawa Dental University","ror":"https://ror.org/0514c4d93","country_code":"JP","type":"education","lineage":["https://openalex.org/I47951555"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobushiro Hamada","raw_affiliation_strings":["Division of Microbiology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan","institution_ids":["https://openalex.org/I47951555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036829265","display_name":"Yoshiyuki Oi","orcid":"https://orcid.org/0000-0002-9070-2449","observed_orcids":["https://orcid.org/0000-0002-9070-2449"]},"institutions":[{"id":"https://openalex.org/I104946051","display_name":"Nihon University","ror":"https://ror.org/05jk51a88","country_code":"JP","type":"education","lineage":["https://openalex.org/I104946051"]},{"id":"https://openalex.org/I4405286816","display_name":"Dental Research Center, School of Dentistry, Nihon University","ror":"https://ror.org/0362w2x54","country_code":"JP","type":"facility","lineage":["https://openalex.org/I104946051","https://openalex.org/I4405286816"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiyuki Oi","raw_affiliation_strings":["Department of Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan","Division of Immunology and Pathology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan","institution_ids":["https://openalex.org/I104946051"]},{"raw_affiliation_string":"Division of Immunology and Pathology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan","institution_ids":["https://openalex.org/I104946051","https://openalex.org/I4405286816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047196134","display_name":"Makoto Makishima","orcid":"https://orcid.org/0000-0002-4630-905X","observed_orcids":["https://orcid.org/0000-0002-4630-905X"]},"institutions":[{"id":"https://openalex.org/I104946051","display_name":"Nihon University","ror":"https://ror.org/05jk51a88","country_code":"JP","type":"education","lineage":["https://openalex.org/I104946051"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Makishima","raw_affiliation_strings":["Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I104946051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100330542","display_name":"Yi Fan Liu","orcid":"https://orcid.org/0000-0002-4998-5547","observed_orcids":["https://orcid.org/0000-0002-4998-5547"]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Liu","raw_affiliation_strings":["Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing, People's Republic of China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011293732","display_name":"UJJAL KUMAR BHAWAL","orcid":"https://orcid.org/0000-0002-3746-009X","observed_orcids":["https://orcid.org/0000-0002-3746-009X"]},"institutions":[{"id":"https://openalex.org/I104946051","display_name":"Nihon University","ror":"https://ror.org/05jk51a88","country_code":"JP","type":"education","lineage":["https://openalex.org/I104946051"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Ujjal K. Bhawal","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry At Matsudo, Chiba, Japan. bhawal.ujjal.kumar@nihon-u.ac.jp","Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry At Matsudo, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry At Matsudo, Chiba, Japan. bhawal.ujjal.kumar@nihon-u.ac.jp","institution_ids":["https://openalex.org/I104946051"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry At Matsudo, Chiba, Japan","institution_ids":["https://openalex.org/I104946051"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5011293732"],"corresponding_institution_ids":["https://openalex.org/I104946051","https://openalex.org/I183519381"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":null,"fwci":2.879,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.91071694,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"48","issue":"2","first_page":"1423","last_page":"1431"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.4399000108242035,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dec1","display_name":"DEC1","score":0.8360000252723694},{"id":"https://openalex.org/keywords/autophagy","display_name":"autophagy","score":0.9769999980926514},{"id":"https://openalex.org/keywords/periodontal-ligament-fibroblasts","display_name":"periodontal ligament fibroblasts","score":0.996999979019165},{"id":"https://openalex.org/keywords/periodontal-inflammation","display_name":"periodontal inflammation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/porphyromonas-gingivalis","display_name":"Porphyromonas gingivalis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/akt-mtor-signaling-pathway","display_name":"Akt/mTOR signaling","score":0.9639999866485596},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8880000114440918},{"id":"https://openalex.org/keywords/beclin-1","display_name":"Beclin-1","score":0.8199999928474426},{"id":"https://openalex.org/keywords/atg5","display_name":"ATG5","score":0.8379999995231628},{"id":"https://openalex.org/keywords/lc3","display_name":"LC3","score":0.9739999771118164},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.8925184607505798},{"id":"https://openalex.org/C2780183776","wikidata":"https://www.wikidata.org/wiki/Q3214147","display_name":"Porphyromonas gingivalis","level":3,"score":0.6085820198059082},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.5308448076248169},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5240542888641357},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.5141565799713135},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.5047086477279663},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.49772003293037415},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.4551432728767395},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4382096827030182},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2803190350532532},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.27788233757019043},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17394396662712097},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17266374826431274},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09752166271209717},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.06507283449172974},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000071186","descriptor_name":"Beclin-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000071187","descriptor_name":"Autophagy-Related Protein 5","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008869","descriptor_name":"Microtubule-Associated Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010513","descriptor_name":"Periodontal Ligament","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016966","descriptor_name":"Porphyromonas gingivalis","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051792","descriptor_name":"Basic Helix-Loop-Helix Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051792","descriptor_name":"Basic Helix-Loop-Helix Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D058570","descriptor_name":"TOR Serine-Threonine Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11033-021-06162-x","doi":"https://doi.org/10.1007/s11033-021-06162-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11033-021-06162-x","pdf_url":null,"source":{"id":"https://openalex.org/S197962172","display_name":"Molecular Biology Reports","issn_l":"0301-4851","issn":["0301-4851","1573-4978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Reports","raw_type":"journal-article"},{"id":"pmid:33507476","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33507476","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular biology reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6601360541","display_name":"The role of circadian abnormalities in salivary gland disorders","funder_award_id":"18K09922","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1586362463","https://openalex.org/W1587016383","https://openalex.org/W1977841275","https://openalex.org/W1985124617","https://openalex.org/W1990138203","https://openalex.org/W1996001348","https://openalex.org/W2014926635","https://openalex.org/W2020340498","https://openalex.org/W2028536701","https://openalex.org/W2046579962","https://openalex.org/W2046747208","https://openalex.org/W2070002019","https://openalex.org/W2095919534","https://openalex.org/W2144224215","https://openalex.org/W2153535991","https://openalex.org/W2164998112","https://openalex.org/W2169663073","https://openalex.org/W2171279050","https://openalex.org/W2173834636","https://openalex.org/W2260998168","https://openalex.org/W2267713729","https://openalex.org/W2307826413","https://openalex.org/W2333837809","https://openalex.org/W2606648391","https://openalex.org/W2626811718","https://openalex.org/W2772230934","https://openalex.org/W2806341699","https://openalex.org/W2883981538","https://openalex.org/W2891534760","https://openalex.org/W2913268077","https://openalex.org/W2948491359","https://openalex.org/W2948943913","https://openalex.org/W3012135238","https://openalex.org/W3020944941","https://openalex.org/W3035736231","https://openalex.org/W3047287510"],"related_works":["https://openalex.org/W3109454741","https://openalex.org/W3177041398","https://openalex.org/W2288417576","https://openalex.org/W2891534760","https://openalex.org/W3155186516","https://openalex.org/W3000173779","https://openalex.org/W2976759598","https://openalex.org/W2046579962","https://openalex.org/W4401832814","https://openalex.org/W3025701068"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-02-01T00:00:00"}