{"id":"https://openalex.org/W3125817152","doi":"https://doi.org/10.1080/10406638.2020.1871039","title":"Ionic Liquid as Green and Recyclable Solvent for the Synthesis of Pyrazinoquinazolines: Study of Antioxidant Activity","display_name":"Ionic Liquid as Green and Recyclable Solvent for the Synthesis of Pyrazinoquinazolines: Study of Antioxidant Activity","publication_year":2021,"publication_date":"2021-01-13","ids":{"openalex":"https://openalex.org/W3125817152","doi":"https://doi.org/10.1080/10406638.2020.1871039","mag":"3125817152"},"language":"en","primary_location":{"id":"doi:10.1080/10406638.2020.1871039","doi":"https://doi.org/10.1080/10406638.2020.1871039","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10406638.2020.1871039","pdf_url":null,"source":{"id":"https://openalex.org/S178924077","display_name":"Polycyclic aromatic compounds","issn_l":"1026-7743","issn":["1026-7743","1040-6638","1563-5333"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polycyclic Aromatic Compounds","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3125817152"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049197490","display_name":"Fatemeh Sheikholeslami\u2010Farahani","orcid":"https://orcid.org/0000-0002-7213-8645","observed_orcids":["https://orcid.org/0000-0002-7213-8645"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I4210103782","display_name":"Islamic Azad University, Firoozkooh Branch","ror":"https://ror.org/025eayv75","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210103782"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Fatemeh Sheikholeslami-Farahani","raw_affiliation_strings":["Department of Chemistry, Firoozkooh Branch, Islamic Azad University","Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Firoozkooh Branch, Islamic Azad University","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I4210103782"]},{"raw_affiliation_string":"Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran","institution_ids":["https://openalex.org/I4210103782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082152069","display_name":"Abdollah Sadeghi Marasht","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I4210152512","display_name":"Islamic Azad University Pharmaceutical Sciences Branch","ror":"https://ror.org/04sssnv16","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210152512"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Abdollah Sadeghi Marasht","raw_affiliation_strings":["Active Pharmaceutical Ingeredients Research Center (APIRC), Tehran Medicinal Science Branch, Islamic Azad University","Active Pharmaceutical Ingeredients Research Center (APIRC), Tehran Medicinal Science Branch, Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Active Pharmaceutical Ingeredients Research Center (APIRC), Tehran Medicinal Science Branch, Islamic Azad University","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I4210152512"]},{"raw_affiliation_string":"Active Pharmaceutical Ingeredients Research Center (APIRC), Tehran Medicinal Science Branch, Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I4210152512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017130920","display_name":"Ali Mirabi","orcid":"https://orcid.org/0000-0002-8038-2795","observed_orcids":["https://orcid.org/0000-0002-8038-2795"]},"institutions":[{"id":"https://openalex.org/I4210138903","display_name":"Qaemshahr Islamic Azad University","ror":"https://ror.org/03y0dv989","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210138903"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Ali Mirabi","raw_affiliation_strings":["Department of Chemistry, Qaemshahr Branch, Islamic Azad University","Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Qaemshahr Branch, Islamic Azad University","institution_ids":["https://openalex.org/I4210138903"]},{"raw_affiliation_string":"Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran","institution_ids":["https://openalex.org/I4210138903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037323772","display_name":"Maryam Ghazvini","orcid":"https://orcid.org/0000-0002-9026-8531","observed_orcids":["https://orcid.org/0000-0002-9026-8531"]},"institutions":[{"id":"https://openalex.org/I55547365","display_name":"Payame Noor University","ror":"https://ror.org/031699d98","country_code":"IR","type":"education","lineage":["https://openalex.org/I55547365"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Maryam Ghazvini","raw_affiliation_strings":["Department of Chemistry, Payame Noor University","Department of Chemistry, Payame Noor University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Payame Noor University","institution_ids":["https://openalex.org/I55547365"]},{"raw_affiliation_string":"Department of Chemistry, Payame Noor University, Tehran, Iran","institution_ids":["https://openalex.org/I55547365"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050309271","display_name":"Mohammad Hosseinnasab Rostam","orcid":"https://orcid.org/0000-0003-4619-9492","observed_orcids":["https://orcid.org/0000-0003-4619-9492"]},"institutions":[{"id":"https://openalex.org/I4210138903","display_name":"Qaemshahr Islamic Azad University","ror":"https://ror.org/03y0dv989","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I4210138903"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Hosseinnasab Rostam","raw_affiliation_strings":["Department of Chemistry, Qaemshahr Branch, Islamic Azad University","Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Qaemshahr Branch, Islamic Azad University","institution_ids":["https://openalex.org/I4210138903"]},{"raw_affiliation_string":"Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran","institution_ids":["https://openalex.org/I4210138903"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5049197490"],"corresponding_institution_ids":["https://openalex.org/I110525433","https://openalex.org/I4210103782"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.00711911,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"42","issue":"6","first_page":"3663","last_page":"3674"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12318","display_name":"Quinazolinone synthesis and applications","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10480","display_name":"Ionic liquids properties and applications","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ionic-liquids","display_name":"ionic liquids","score":0.9509999752044678},{"id":"https://openalex.org/keywords/green-solvents","display_name":"green solvents","score":0.7919999957084656},{"id":"https://openalex.org/keywords/recyclable-solvents","display_name":"recyclable solvents","score":0.8859999775886536},{"id":"https://openalex.org/keywords/four-component-reaction","display_name":"four-component reaction","score":0.9160000085830688},{"id":"https://openalex.org/keywords/alpha-halo-ketones","display_name":"\u03b1-haloketones","score":0.9890000224113464},{"id":"https://openalex.org/keywords/activated-acetylenes","display_name":"activated acetylenes","score":0.8410000205039978},{"id":"https://openalex.org/keywords/ethyl-bromoacetate","display_name":"ethyl bromoacetate","score":0.996999979019165},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8840000033378601},{"id":"https://openalex.org/keywords/dpph-radical-scavenging-activity","display_name":"DPPH radical scavenging","score":0.9879999756813049},{"id":"https://openalex.org/keywords/ferric-reducing-power","display_name":"ferric reducing power","score":0.890999972820282},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9524619579315186},{"id":"https://openalex.org/C154881586","wikidata":"https://www.wikidata.org/wiki/Q898579","display_name":"Ionic liquid","level":3,"score":0.946561336517334},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.7087982892990112},{"id":"https://openalex.org/C91558341","wikidata":"https://www.wikidata.org/wiki/Q725361","display_name":"Green chemistry","level":4,"score":0.6841475963592529},{"id":"https://openalex.org/C2780534640","wikidata":"https://www.wikidata.org/wiki/Q3233795","display_name":"Ferric","level":2,"score":0.5843209624290466},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.5619856715202332},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.4926021695137024},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.46130022406578064},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.3455893397331238},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.34235143661499023},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/10406638.2020.1871039","doi":"https://doi.org/10.1080/10406638.2020.1871039","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10406638.2020.1871039","pdf_url":null,"source":{"id":"https://openalex.org/S178924077","display_name":"Polycyclic aromatic compounds","issn_l":"1026-7743","issn":["1026-7743","1040-6638","1563-5333"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Polycyclic Aromatic Compounds","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.807699978351593,"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W165548560","https://openalex.org/W1572832338","https://openalex.org/W1964733965","https://openalex.org/W1964957521","https://openalex.org/W1965336187","https://openalex.org/W1972430944","https://openalex.org/W1981796193","https://openalex.org/W1991531690","https://openalex.org/W1996132368","https://openalex.org/W2003848126","https://openalex.org/W2007985760","https://openalex.org/W2011673428","https://openalex.org/W2012747443","https://openalex.org/W2018587864","https://openalex.org/W2018985818","https://openalex.org/W2031188171","https://openalex.org/W2036399249","https://openalex.org/W2037397042","https://openalex.org/W2044153827","https://openalex.org/W2048025186","https://openalex.org/W2048285031","https://openalex.org/W2051482330","https://openalex.org/W2056756372","https://openalex.org/W2060213751","https://openalex.org/W2067491847","https://openalex.org/W2077799827","https://openalex.org/W2084318193","https://openalex.org/W2086037731","https://openalex.org/W2086707882","https://openalex.org/W2087796938","https://openalex.org/W2089186520","https://openalex.org/W2100707919","https://openalex.org/W2106505642","https://openalex.org/W2106942217","https://openalex.org/W2109522650","https://openalex.org/W2111399172","https://openalex.org/W2111677437","https://openalex.org/W2113910845","https://openalex.org/W2120235566","https://openalex.org/W2127378043","https://openalex.org/W2128872743","https://openalex.org/W2131739694","https://openalex.org/W2132430262","https://openalex.org/W2142108294","https://openalex.org/W2172350422","https://openalex.org/W2176572634","https://openalex.org/W2237444342","https://openalex.org/W2243349274","https://openalex.org/W2316648745","https://openalex.org/W2339810942","https://openalex.org/W2464500809","https://openalex.org/W2522329958","https://openalex.org/W2556672629","https://openalex.org/W2576108086","https://openalex.org/W2616192673","https://openalex.org/W2890497260","https://openalex.org/W2900454864","https://openalex.org/W2919304593","https://openalex.org/W2944063368","https://openalex.org/W2944484624","https://openalex.org/W2950090313","https://openalex.org/W2950473072","https://openalex.org/W2950802096","https://openalex.org/W2952027929","https://openalex.org/W2953202814","https://openalex.org/W2986497830","https://openalex.org/W3007126601","https://openalex.org/W3015848577","https://openalex.org/W3038918956","https://openalex.org/W4211151270","https://openalex.org/W4230291024","https://openalex.org/W4230739685","https://openalex.org/W4233880233","https://openalex.org/W4247319996","https://openalex.org/W4299407806"],"related_works":["https://openalex.org/W7204483182","https://openalex.org/W2483716249","https://openalex.org/W4414573215","https://openalex.org/W2275994844","https://openalex.org/W2951938191","https://openalex.org/W2605363954","https://openalex.org/W2949166626","https://openalex.org/W4387955040","https://openalex.org/W2024011370","https://openalex.org/W2759585803"],"abstract_inverted_index":{"The":[0,79],"preparation":[1,106],"of":[2,14,44,57,76,89,96,107,119,151],"pyrazinoquinazoline":[3,108],"derivatives":[4],"are":[5],"performed":[6,48],"in":[7,23,39,125],"high":[8,149],"yields":[9,150],"by":[10,49,52,70],"four":[11,110],"component":[12],"reactions":[13],"isoquinolin-3-ylmethanamine,":[15],"\u03b1-haloketones,":[16],"activated":[17],"acetylenic":[18],"compounds":[19,65],"and":[20,54,72,93,139,145],"ethyl":[21],"bromoacetate":[22],"ionic":[24,126,133],"liquid":[25,127,134],"as":[26,102,109,128,141],"green":[27,91,130],"media":[28,92],"at":[29],"room":[30],"temperature.":[31],"In":[32],"addition,":[33],"due":[34],"to":[35],"having":[36],"quinazoline":[37],"core":[38],"the":[40,83,105,117],"synthesized":[41,64],"compounds,":[42],"evaluation":[43],"antioxidant":[45],"activity":[46],"was":[47,100],"radical":[50,68],"trapping":[51,69],"DPPH":[53,71],"reducing":[55,74],"power":[56],"ferric":[58,77],"ion":[59],"experiments.":[60],"As":[61],"a":[62,129],"result,":[63],"showed":[66],"low":[67],"good":[73],"ability":[75],"ion.":[78],"current":[80],"procedure":[81,115,123],"has":[82],"benefits":[84],"for":[85,104],"instance":[86],"excellent":[87],"yield":[88],"reaction,":[90],"easy":[94],"separation":[95],"product.":[97],"HighlightsIonic":[98],"Liquid":[99],"used":[101],"solvent":[103,147],"cyclic":[111],"heteroaromatic":[112],"systems.The":[113],"present":[114,122],"avoids":[116],"use":[118],"toxic":[120],"solvent.The":[121],"runs":[124],"media.This":[131],"recoverable":[132],"makes":[135],"this":[136],"protocol":[137],"attractive":[138],"useful":[140],"an":[142],"industrially":[143],"viable":[144],"eco-safe":[146],"with":[148],"products.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-02-01T00:00:00"}