{"id":"https://openalex.org/W3125816274","doi":"https://doi.org/10.1097/aln.0000000000003689","title":"Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles","display_name":"Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles","publication_year":2021,"publication_date":"2021-01-27","ids":{"openalex":"https://openalex.org/W3125816274","doi":"https://doi.org/10.1097/aln.0000000000003689","mag":"3125816274","pmid":"https://pubmed.ncbi.nlm.nih.gov/33503656","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8054817"},"language":"en","primary_location":{"id":"doi:10.1097/aln.0000000000003689","doi":"https://doi.org/10.1097/aln.0000000000003689","is_oa":false,"landing_page_url":"https://doi.org/10.1097/aln.0000000000003689","pdf_url":null,"source":{"id":"https://openalex.org/S124035732","display_name":"Anesthesiology","issn_l":"0003-3022","issn":["0003-3022","1528-1175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anesthesiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8054817","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086401839","display_name":"Ian J. 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Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051080788","display_name":"Philip J. 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Norris","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . 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Mauermann","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . 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Podgoreanu","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . 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Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068559880","display_name":"Chelsea M. Conn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405258483","display_name":"Vitalant Research Institute","ror":"https://ror.org/00r2ye360","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157777","https://openalex.org/I4405258483"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chelsea M. Conn","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","institution_ids":[]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I170897317","https://openalex.org/I180670191","https://openalex.org/I4210126298","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013212586","display_name":"Laurie A. Meade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405258483","display_name":"Vitalant Research Institute","ror":"https://ror.org/00r2ye360","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157777","https://openalex.org/I4405258483"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie Meade","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","institution_ids":[]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I170897317","https://openalex.org/I180670191","https://openalex.org/I4210126298","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061662161","display_name":"Tamara Cannon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405258483","display_name":"Vitalant Research Institute","ror":"https://ror.org/00r2ye360","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157777","https://openalex.org/I4405258483"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamara Cannon","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","institution_ids":[]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I170897317","https://openalex.org/I180670191","https://openalex.org/I4210126298","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059924108","display_name":"Sheila Marie Keating","orcid":"https://orcid.org/0000-0002-8324-3694","observed_orcids":["https://orcid.org/0000-0002-8324-3694"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405258483","display_name":"Vitalant Research Institute","ror":"https://ror.org/00r2ye360","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157777","https://openalex.org/I4405258483"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheila M. Keating","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","institution_ids":[]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I170897317","https://openalex.org/I180670191","https://openalex.org/I4210126298","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","institution_ids":[]},{"raw_affiliation_string":"This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","institution_ids":[]},{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","institution_ids":["https://openalex.org/I180670191","https://openalex.org/I4405258483"]},{"raw_affiliation_string":"Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","institution_ids":["https://openalex.org/I4405258483","https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008321671","display_name":"Christopher C. Silliman","orcid":"https://orcid.org/0000-0002-1498-1933","observed_orcids":["https://orcid.org/0000-0002-1498-1933"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405258483","display_name":"Vitalant Research Institute","ror":"https://ror.org/00r2ye360","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210157777","https://openalex.org/I4405258483"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher C. Silliman","raw_affiliation_strings":["Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . This article may be accessed for personal use at no charge through the Journal Web site, www.anesthesiology.org","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.); Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.); Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota; and Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)","Submitted for publication April 13, 2020. Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . 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Accepted for publication December 28, 2020","This article is featured in \u201cThis Month in Anesthesiology,\u201d page 1A","Department of Anesthesiology and Perioperative Medicine (W.J.M., L.M., D.J.K.), Transfusion Medicine Services (C.M.C.), and Division of Biomedical Statistics and Informatics (P.J.S.), Mayo Clinic, Rochester, Minnesota","From the Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina (I.J.W., M.V.P., T.C.)","Vitalant Research Institute and the Departments of Laboratory Medicine and Medicine, University of California, San Francisco, San Francisco, California (P.J.N., S.M.K.)","Vitalant Research Institute and the Departments of Pediatrics and Surgery, School of Medicine, University of Colorado, Aurora, Colorado (C.C.S., M.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Address correspondence to Dr. Welsby: 2301 Erwin Road, 5691H HAFS Building, Durham, North Carolina 27710. . 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