{"id":"https://openalex.org/W3124614727","doi":"https://doi.org/10.1080/08923973.2020.1869255","title":"The impact of ellagic acid on some apoptotic gene expressions: a new perspective for the regulation of pancreatic Nrf-2/NF-\u03baB and Akt/VEGF signaling in CCl4-induced pancreas damage in rats","display_name":"The impact of ellagic acid on some apoptotic gene expressions: a new perspective for the regulation of pancreatic Nrf-2/NF-\u03baB and Akt/VEGF signaling in CCl4-induced pancreas damage in rats","publication_year":2021,"publication_date":"2021-01-17","ids":{"openalex":"https://openalex.org/W3124614727","doi":"https://doi.org/10.1080/08923973.2020.1869255","mag":"3124614727","pmid":"https://pubmed.ncbi.nlm.nih.gov/33455449"},"language":"en","primary_location":{"id":"doi:10.1080/08923973.2020.1869255","doi":"https://doi.org/10.1080/08923973.2020.1869255","is_oa":false,"landing_page_url":"https://doi.org/10.1080/08923973.2020.1869255","pdf_url":null,"source":{"id":"https://openalex.org/S16829457","display_name":"Immunopharmacology and Immunotoxicology","issn_l":"0892-3973","issn":["0892-3973","1532-2513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunopharmacology and Immunotoxicology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/11508/57691","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071241665","display_name":"Abdullah Nabi Aslan","orcid":"https://orcid.org/0000-0002-6243-4221","observed_orcids":["https://orcid.org/0000-0002-6243-4221"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Abdullah Aslan","raw_affiliation_strings":["Department of Biology-Molecular Biology and Genetics Program, Faculty of Science, Firat University, Elazig, Turkey"],"raw_orcid":"https://orcid.org/0000-0002-6243-4221","affiliations":[{"raw_affiliation_string":"Department of Biology-Molecular Biology and Genetics Program, Faculty of Science, Firat University, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057792489","display_name":"Seda Beyaz","orcid":"https://orcid.org/0000-0003-0436-8112","observed_orcids":["https://orcid.org/0000-0003-0436-8112"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Seda Beyaz","raw_affiliation_strings":["Department of Biology, Faculty of Science, Firat University, Elazig, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, Firat University, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084544026","display_name":"\u00d6zlem G\u00f6k","orcid":"https://orcid.org/0000-0001-8521-6369","observed_orcids":["https://orcid.org/0000-0001-8521-6369"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ozlem Gok","raw_affiliation_strings":["Department of Biology, Faculty of Science, Firat University, Elazig, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, Firat University, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003413303","display_name":"Muhammed \u0130smail Can","orcid":"https://orcid.org/0000-0002-0118-2278","observed_orcids":["https://orcid.org/0000-0002-0118-2278"]},"institutions":[{"id":"https://openalex.org/I20126385","display_name":"Inonu University","ror":"https://ror.org/04asck240","country_code":"TR","type":"education","lineage":["https://openalex.org/I20126385"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Muhammed Ismail Can","raw_affiliation_strings":["Department of Biology, Faculty of Science, Inonu University, Malatya, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, Inonu University, Malatya, Turkey","institution_ids":["https://openalex.org/I20126385"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085265503","display_name":"Fazilet Erman","orcid":"https://orcid.org/0000-0001-5181-4053","observed_orcids":["https://orcid.org/0000-0001-5181-4053"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fazilet Erman","raw_affiliation_strings":["Faculty of Health Sciences, Firat University, Elazig, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, Firat University, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036783598","display_name":"Orhan Erman","orcid":"https://orcid.org/0000-0002-4300-0452","observed_orcids":["https://orcid.org/0000-0002-4300-0452"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Orhan Erman","raw_affiliation_strings":["Department of Biology, Faculty of Science, Firat University, Elazig, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, Firat University, Elazig, Turkey","institution_ids":["https://openalex.org/I143396566"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5071241665"],"corresponding_institution_ids":["https://openalex.org/I143396566"],"apc_list":null,"apc_paid":null,"fwci":3.604,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.93565844,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"43","issue":"2","first_page":"145","last_page":"152"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.7851999998092651,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.7851999998092651,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.06809999793767929,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11332","display_name":"Genomics, phytochemicals, and oxidative stress","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ellagic-acid","display_name":"ellagic acid","score":1.0},{"id":"https://openalex.org/keywords/pancreatic-injury","display_name":"pancreatic injury","score":0.843999981880188},{"id":"https://openalex.org/keywords/nrf2","display_name":"Nrf2","score":0.8149999976158142},{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.9639999866485596},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.9860000014305115},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9110000133514404},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9789999723434448},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8510000109672546},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.7179999947547913},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.9179999828338623},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9750000238418579},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8870000243186951}],"concepts":[{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.6361255645751953},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.5500232577323914},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.523621141910553},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.522439181804657},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49810791015625},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.46193090081214905},{"id":"https://openalex.org/C2781464872","wikidata":"https://www.wikidata.org/wiki/Q422044","display_name":"Ellagic acid","level":4,"score":0.4292457103729248},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3991406559944153},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3468434810638428},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32702866196632385},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26774948835372925},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19774097204208374},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.18968123197555542},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07206696271896362},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002251","descriptor_name":"Carbon Tetrachloride","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D004610","descriptor_name":"Ellagic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D051057","descriptor_name":"Proto-Oncogene Proteins c-akt","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1080/08923973.2020.1869255","doi":"https://doi.org/10.1080/08923973.2020.1869255","is_oa":false,"landing_page_url":"https://doi.org/10.1080/08923973.2020.1869255","pdf_url":null,"source":{"id":"https://openalex.org/S16829457","display_name":"Immunopharmacology and Immunotoxicology","issn_l":"0892-3973","issn":["0892-3973","1532-2513"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunopharmacology and Immunotoxicology","raw_type":"journal-article"},{"id":"pmid:33455449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33455449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunopharmacology and immunotoxicology","raw_type":"Journal Article"},{"id":"pmh:oai:openaccess.firat.edu.tr:11508/57691","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11508/57691","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:openaccess.firat.edu.tr:11508/57691","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11508/57691","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335557","display_name":"Firat University Scientific Research Projects Management Unit","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1457781966","https://openalex.org/W1536966206","https://openalex.org/W1974409426","https://openalex.org/W1983310681","https://openalex.org/W1996683856","https://openalex.org/W2007108460","https://openalex.org/W2008576603","https://openalex.org/W2035397939","https://openalex.org/W2043041807","https://openalex.org/W2059025220","https://openalex.org/W2084263514","https://openalex.org/W2090695110","https://openalex.org/W2091430330","https://openalex.org/W2100837269","https://openalex.org/W2146696997","https://openalex.org/W2161303735","https://openalex.org/W2176901216","https://openalex.org/W2275212339","https://openalex.org/W2284878011","https://openalex.org/W2312473524","https://openalex.org/W2495268609","https://openalex.org/W2615651686","https://openalex.org/W2747858303","https://openalex.org/W2799516209","https://openalex.org/W2805752549","https://openalex.org/W2807711030","https://openalex.org/W2811385326","https://openalex.org/W2899631640","https://openalex.org/W2900865405","https://openalex.org/W2901601146","https://openalex.org/W2904104631","https://openalex.org/W2996873517","https://openalex.org/W3009762687","https://openalex.org/W3014187538","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W3014187538","https://openalex.org/W2495268609","https://openalex.org/W3009762687","https://openalex.org/W2807711030","https://openalex.org/W2741177402","https://openalex.org/W2009491438","https://openalex.org/W2043041807","https://openalex.org/W3029363381","https://openalex.org/W3141607287","https://openalex.org/W3091426750"],"abstract_inverted_index":{"Objective":[0],"The":[1,34],"aim":[2],"of":[3,12,19,36,60],"this":[4,80],"study":[5],"was":[6,174],"to":[7,26,97,211],"evaluate":[8],"the":[9,17,58,181,212,241],"potential":[10],"effect":[11,73],"ellagic":[13],"acid":[14],"(EA)":[15],"in":[16,205,224,240],"treatment":[18],"pancreatic":[20],"injury.":[21],"EA":[22,37,113,123,206,219,228],"has":[23,52,68],"been":[24,48,53],"found":[25],"have":[27,47],"strong":[28],"anti-inflammatory,":[29],"antioxidative,":[30],"and":[31,44,50,64,77,100,133,140,151,164,171,183,189,197,201,226],"anticancer":[32],"properties.":[33],"effects":[35],"on":[38,74],"pancreati\u02dcc":[39],"star":[40],"cell":[41,45,62],"(PSC)":[42],"activation":[43,59],"functions":[46,63],"evaluated":[49],"it":[51,56,67],"shown":[54],"that":[55,218,227],"inhibits":[57],"basic":[61],"PSCs":[65],"and.":[66],"antidiabetic":[69],"activity":[70,163],"through":[71],"its":[72],"\u03b2-pancreas":[75],"cells.Materials":[76],"methods":[78],"In":[79,142,178],"work,":[81],"36":[82],"Wistar":[83],"albino":[84],"rats":[85,102,225],"(n":[86],"=":[87],"36,":[88],"8":[89,131],"weeks":[90,132],"old)":[91],"were":[92,95,103,128,138,156,167],"used.":[93],"Rats":[94],"divided":[96],"4":[98],"groups":[99],"9":[101],"each":[104],"group.":[105,126],"Groups:":[106],"Group":[107,111,115,121],"1:":[108],"control":[109],"group;":[110,114,120],"2:":[112],"3:":[116],"carbon":[117],"tetrachloride":[118],"(CCl4)":[119],"4:":[122],"+":[124,207],"CCl4":[125,208,213],"Animals":[127],"decapitated":[129],"after":[130],"their":[134],"pancreas":[135,143,221,237],"tissue":[136,222,238],"samples":[137],"taken":[139],"researched.":[141],"tissue,":[144],"NF-\u03baB,":[145,194],"TNF-\u03b1,":[146,193],"Nrf-2,":[147],"VEGF,":[148,196],"Bcl-2,":[149,195],"caspase-3,":[150],"Akt":[152,198],"proteins":[153],"expression":[154],"ratios":[155],"analyzed":[157],"by":[158,169,176],"western":[159],"blotting":[160],"method,":[161],"CAT":[162],"GSH":[165,190],"levels":[166,191,203],"determined":[168],"spectrophotometer":[170],"ROS":[172],"production":[173],"detected":[175],"MDA.Results":[177],"our":[179],"results,":[180],"Nrf-2":[182],"caspase-3":[184],"protein":[185,199],"expressions,":[186],"catalase":[187],"activities":[188],"increased,":[192],"expressions":[200],"MDA":[202],"reduced":[204],"group":[209],"comparable":[210],"group.Conclusions":[214],"These":[215],"findings":[216],"reveal":[217],"decreases":[220],"injury":[223,239],"may":[229],"also":[230],"be":[231],"used":[232],"as":[233],"a":[234],"drug":[235],"against":[236],"future.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-02-01T00:00:00"}