{"id":"https://openalex.org/W3124564426","doi":null,"title":"\u041f\u0440\u043e\u0431\u043b\u0435\u043c\u0430 \u043d\u0435\u0430\u043b\u043a\u043e\u0433\u043e\u043b\u044c\u043d\u043e\u0457 \u0436\u0438\u0440\u043e\u0432\u043e\u0457 \u0445\u0432\u043e\u0440\u043e\u0431\u0438 \u043f\u0435\u0447\u0456\u043d\u043a\u0438, \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0456\u0447\u043d\u043e\u0433\u043e \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0443 \u0442\u0430 \u0430\u0442\u0435\u0440\u043e\u0441\u043a\u043b\u0435\u0440\u043e\u0437\u0443: \u0432\u0456\u0434 \u0454\u0434\u043d\u043e\u0441\u0442\u0456 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0437\u0443 \u0434\u043e \u043c\u043e\u0436\u043b\u0438\u0432\u043e\u0441\u0442\u0456 \u043a\u043e\u0440\u0435\u043a\u0446\u0456\u0457 \u0443\u0440\u0441\u043e\u0434\u0435\u0437\u043e\u043a\u0441\u0438\u0445\u043e\u043b\u0435\u0432\u043e\u044e \u043a\u0438\u0441\u043b\u043e\u0442\u043e\u044e","display_name":"\u041f\u0440\u043e\u0431\u043b\u0435\u043c\u0430 \u043d\u0435\u0430\u043b\u043a\u043e\u0433\u043e\u043b\u044c\u043d\u043e\u0457 \u0436\u0438\u0440\u043e\u0432\u043e\u0457 \u0445\u0432\u043e\u0440\u043e\u0431\u0438 \u043f\u0435\u0447\u0456\u043d\u043a\u0438, \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0456\u0447\u043d\u043e\u0433\u043e \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0443 \u0442\u0430 \u0430\u0442\u0435\u0440\u043e\u0441\u043a\u043b\u0435\u0440\u043e\u0437\u0443: \u0432\u0456\u0434 \u0454\u0434\u043d\u043e\u0441\u0442\u0456 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0437\u0443 \u0434\u043e \u043c\u043e\u0436\u043b\u0438\u0432\u043e\u0441\u0442\u0456 \u043a\u043e\u0440\u0435\u043a\u0446\u0456\u0457 \u0443\u0440\u0441\u043e\u0434\u0435\u0437\u043e\u043a\u0441\u0438\u0445\u043e\u043b\u0435\u0432\u043e\u044e \u043a\u0438\u0441\u043b\u043e\u0442\u043e\u044e","publication_year":2020,"publication_date":"2020-11-16","ids":{"openalex":"https://openalex.org/W3124564426","mag":"3124564426"},"language":"uk","primary_location":{"id":"mag:3124564426","doi":null,"is_oa":true,"landing_page_url":"http://sgastro.com.ua/article/view/MG-2020-5-46","pdf_url":null,"source":{"id":"https://openalex.org/S4210199486","display_name":"Modern Gastroenterology","issn_l":"1727-5725","issn":["1727-5725","2521-649X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Modern Gastroenterology","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://sgastro.com.ua/article/view/MG-2020-5-46","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021041321","display_name":"\u041d. \u0411. \u0413\u0443\u0431\u0435\u0440\u0433\u0440\u0438\u0446","orcid":"https://orcid.org/0000-0003-3655-9554","observed_orcids":["https://orcid.org/0000-0003-3655-9554"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u041d. \u0411. \u0413\u0443\u0431\u0435\u0440\u0433\u0440\u0438\u0446","raw_affiliation_strings":["\u041c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u00ab\u041c\u0435\u0434\u0456\u043a\u0430\u043f\u00bb, \u041e\u0434\u0435\u0441\u0430"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u041c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u00ab\u041c\u0435\u0434\u0456\u043a\u0430\u043f\u00bb, \u041e\u0434\u0435\u0441\u0430","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089149965","display_name":"T. L. Mozhyn\u0430","orcid":"https://orcid.org/0000-0001-8239-6093","observed_orcids":["https://orcid.org/0000-0001-8239-6093"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. L. Mozhyn\u0430","raw_affiliation_strings":["\u0426\u0435\u043d\u0442\u0440 \u0437\u0434\u043e\u0440\u043e\u0432\u043e\u0433\u043e \u0441\u0435\u0440\u0446\u044f, \u0425\u0430\u0440\u043a\u0456\u0432"],"raw_orcid":"https://orcid.org/0000-0001-8239-6093","affiliations":[{"raw_affiliation_string":"\u0426\u0435\u043d\u0442\u0440 \u0437\u0434\u043e\u0440\u043e\u0432\u043e\u0433\u043e \u0441\u0435\u0440\u0446\u044f, \u0425\u0430\u0440\u043a\u0456\u0432","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112992473","display_name":"N. V. Byelyayeva","orcid":"https://orcid.org/0000-0001-7571-2406","observed_orcids":["https://orcid.org/0000-0001-7571-2406"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. V. Byelyayeva","raw_affiliation_strings":["\u041c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u00ab\u041c\u0435\u0434\u0456\u043a\u0430\u043f\u00bb, \u041e\u0434\u0435\u0441\u0430"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u041c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u00ab\u041c\u0435\u0434\u0456\u043a\u0430\u043f\u00bb, \u041e\u0434\u0435\u0441\u0430","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8880000114440918},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ursodeoxycholic-acid","display_name":"ursodeoxycholic acid","score":0.9359999895095825},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.7260000109672546},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9559999704360962},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9860000014305115},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.8069999814033508},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.878000020980835},{"id":"https://openalex.org/keywords/atherosclerotic-plaque-formation","display_name":"atherosclerotic plaque formation","score":0.8169999718666077},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9079999923706055},{"id":"https://openalex.org/keywords/coronary-artery-calcification","display_name":"coronary artery calcification","score":0.7749999761581421},{"id":"https://openalex.org/keywords/nafld-fibrosis-score","display_name":"NAFLD fibrosis score","score":0.7609999775886536},{"id":"https://openalex.org/keywords/pleiotropy","display_name":"pleiotropy","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7953201532363892},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7145622968673706},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6634109020233154},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.6163289546966553},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.6004824042320251},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.5780611634254456},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.5264326333999634},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.5248035192489624},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5092276334762573},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4057239592075348},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4020885229110718},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3942986726760864},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3108862340450287},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.14854106307029724}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3124564426","doi":null,"is_oa":true,"landing_page_url":"http://sgastro.com.ua/article/view/MG-2020-5-46","pdf_url":null,"source":{"id":"https://openalex.org/S4210199486","display_name":"Modern Gastroenterology","issn_l":"1727-5725","issn":["1727-5725","2521-649X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Modern Gastroenterology","raw_type":null}],"best_oa_location":{"id":"mag:3124564426","doi":null,"is_oa":true,"landing_page_url":"http://sgastro.com.ua/article/view/MG-2020-5-46","pdf_url":null,"source":{"id":"https://openalex.org/S4210199486","display_name":"Modern Gastroenterology","issn_l":"1727-5725","issn":["1727-5725","2521-649X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Modern Gastroenterology","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W353985841","https://openalex.org/W1152644542","https://openalex.org/W1845696519","https://openalex.org/W1897974851","https://openalex.org/W1966993185","https://openalex.org/W1980770174","https://openalex.org/W1983586642","https://openalex.org/W1985444229","https://openalex.org/W1992328065","https://openalex.org/W1993832782","https://openalex.org/W1995461319","https://openalex.org/W2021131943","https://openalex.org/W2024406341","https://openalex.org/W2027466456","https://openalex.org/W2031058428","https://openalex.org/W2048613643","https://openalex.org/W2056337545","https://openalex.org/W2059360370","https://openalex.org/W2074203821","https://openalex.org/W2086158879","https://openalex.org/W2095557106","https://openalex.org/W2096417404","https://openalex.org/W2109371472","https://openalex.org/W2110756876","https://openalex.org/W2116256276","https://openalex.org/W2122571344","https://openalex.org/W2124507080","https://openalex.org/W2148327131","https://openalex.org/W2162502613","https://openalex.org/W2168706118","https://openalex.org/W2341568598","https://openalex.org/W2399261310","https://openalex.org/W2412911642","https://openalex.org/W2510135464","https://openalex.org/W2519289952","https://openalex.org/W2520937493","https://openalex.org/W2523985864","https://openalex.org/W2550685331","https://openalex.org/W2728979498","https://openalex.org/W2734724639","https://openalex.org/W2743260639","https://openalex.org/W2745540622","https://openalex.org/W2791409258","https://openalex.org/W2885798326","https://openalex.org/W2903438339","https://openalex.org/W2927586902","https://openalex.org/W2997437155","https://openalex.org/W3010345795","https://openalex.org/W3014040916","https://openalex.org/W3015668607","https://openalex.org/W3017252194","https://openalex.org/W3151370373","https://openalex.org/W4388959619"],"related_works":["https://openalex.org/W3046621838","https://openalex.org/W3003324676","https://openalex.org/W3136724397","https://openalex.org/W2925900289","https://openalex.org/W4402413255","https://openalex.org/W4416936017","https://openalex.org/W3210791767","https://openalex.org/W4387344015","https://openalex.org/W4404338056","https://openalex.org/W4403684665"],"abstract_inverted_index":{"Non\u2011alcoholic":[0],"fatty":[1],"liver":[2,11],"disease":[3,22],"(NAFLD)":[4],"is":[5,17,24,76,93],"one":[6],"of":[7,15,27,44,58,64,69,74,81,84,89,99,116,139,153,158,166,174,195,206,212],"the":[8,13,42,62,82,113,128,137,150,156,164,193,203,210],"most":[9],"common":[10,28],"pathologies,":[12],"prevalence":[14],"which":[16,92,117],"steadily":[18],"increasing":[19],"worldwide.":[20],"Cardiovascular":[21],"(CVD)":[23],"another":[25],"group":[26],"diseases":[29],"that":[30],"have":[31,109],"similar":[32],"pathophysiological":[33],"mechanisms":[34],"with":[35,78,107,123,180],"NAFLD.":[36],"CVD":[37],"and":[38,67,87,101,143,160,208],"NAFLD":[39,75,108,129],"occur":[40],"against":[41],"background":[43],"metabolic":[45],"syndrome,":[46],"systemic":[47,140],"insulin":[48,161],"resistance,":[49,162],"oxidative":[50,144],"stress,":[51,145],"altered":[52],"lipid":[53,147],"metabolism.":[54],"The":[55,72,172],"natural":[56],"history":[57],"both":[59],"predisposes":[60],"to":[61,189,201],"development":[63],"endothelial":[65],"dysfunction":[66],"formation/instability":[68],"atherosclerotic":[70,167],"plaques.":[71],"progression":[73,211],"associated":[77],"an":[79,96],"increase":[80,115],"thickness":[83],"intima\u2011media":[85],"complex":[86],"calcification":[88],"coronary":[90],"arteries,":[91],"accompanied":[94],"by":[95],"increased":[97],"risk":[98],"subclinical":[100],"clinically":[102],"significant":[103,175],"atherosclerosis":[104,207],"development.":[105],"Patients":[106],"a\u00a0high":[110],"cardiovascular":[111],"risk,":[112],"maximum":[114],"should":[118],"be":[119],"expected":[120],"in":[121,178,192,199],"patients":[122],"severe":[124],"fibrosis":[125],"(F3\u2011F4":[126],"on":[127],"Fibrosis":[130],"Score":[131],"scale).":[132],"Ursodeoxycholic":[133],"acid":[134],"(UDCA)":[135],"reduces":[136,155],"severity":[138],"inflammatory":[141],"response":[142],"improves":[146],"metabolism,":[148],"increases":[149],"hypolipidemic":[151],"effect":[152],"statins,":[154],"degree":[157],"hyperglycemia":[159],"inhibits":[163],"formation":[165],"plaques,":[168],"has":[169],"vasodilating":[170],"effect.":[171],"presence":[173],"pleiotropic":[176],"properties":[177],"combination":[179],"a\u00a0pronounced":[181],"cytoprotective,":[182],"choleretic,":[183],"antiapoptic,":[184],"anticholestatic,":[185],"immunomodulatory":[186],"activity":[187],"allows":[188],"include":[190],"UDCA":[191],"treatment":[194],"NAFLD,":[196],"non\u2011alcoholic":[197],"steatohepatitis":[198],"order":[200],"reduce":[202],"clinical":[204],"manifestations":[205],"prevent":[209],"CVD.":[213]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-02-01T00:00:00"}