{"id":"https://openalex.org/W3123763418","doi":null,"title":"Therapy-related acute myeloid leukemia and its prevention.","display_name":"Therapy-related acute myeloid leukemia and its prevention.","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3123763418","mag":"3123763418","pmid":"https://pubmed.ncbi.nlm.nih.gov/33489451","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7811901"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:6724729","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7811901","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC7811901","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076325447","display_name":"Gennady A. Belitsky","orcid":"https://orcid.org/0000-0002-3167-7204","observed_orcids":["https://orcid.org/0000-0002-3167-7204"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Gennady Belitsky","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033114109","display_name":"Timur I. Fetisov","orcid":"https://orcid.org/0000-0002-5082-9883","observed_orcids":["https://orcid.org/0000-0002-5082-9883"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Timur Fetisov","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041093616","display_name":"\u041a\u0438\u0440\u0441\u0430\u043d\u043e\u0432 \u041a\u0438\u0440\u0438\u043b\u043b \u0418\u0433\u043e\u0440\u0435\u0432\u0438\u0447","orcid":"https://orcid.org/0000-0002-8599-6833","observed_orcids":["https://orcid.org/0000-0002-8599-6833"]},"institutions":[{"id":"https://openalex.org/I126527374","display_name":"Peoples' Friendship University of Russia","ror":"https://ror.org/02dn9h927","country_code":"RU","type":"education","lineage":["https://openalex.org/I126527374"]},{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Kirill Kirsanov","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","Faculty of Basic Therapy, Peoples' Friendship University of Russia Moscow 117198, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]},{"raw_affiliation_string":"Faculty of Basic Therapy, Peoples' Friendship University of Russia Moscow 117198, Russia","institution_ids":["https://openalex.org/I126527374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080490826","display_name":"Ekaterina A. Lesovaya","orcid":"https://orcid.org/0000-0002-1967-9637","observed_orcids":["https://orcid.org/0000-0002-1967-9637"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]},{"id":"https://openalex.org/I4210141419","display_name":"Ryazan State Medical University named after Academician I.P. Pavlov","ror":"https://ror.org/04nvcbr70","country_code":"RU","type":"education","lineage":["https://openalex.org/I4210141419"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Ekaterina Lesovaya","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","Division of Oncology, Pavlov Ryazan State Medical University Ryazan 390026, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]},{"raw_affiliation_string":"Division of Oncology, Pavlov Ryazan State Medical University Ryazan 390026, Russia","institution_ids":["https://openalex.org/I4210141419"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Olga Vlasova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Olga Vlasova","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077780826","display_name":"\u042f\u043a\u0443\u0431\u043e\u0432\u0441\u043a\u0430\u044f \u041c\u0430\u0440\u0438\u0430\u043d\u043d\u0430 \u0413\u0435\u043d\u043d\u0430\u0434\u0438\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0002-9710-8178","observed_orcids":["https://orcid.org/0000-0002-9710-8178"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Marianna Yakubovskaya","raw_affiliation_strings":["Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Carcinogenesis, Blokhin National Medical Research Center of Oncology, Ministry of Health of Russian Federation Moscow 115478, Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.164,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.53464073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"10","issue":"6","first_page":"416","last_page":"433"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.03310000151395798,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/therapy-related-acute-myeloid-leukemia","display_name":"therapy-related acute myeloid leukemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/secondary-malignancies","display_name":"secondary malignancies","score":0.8339999914169312},{"id":"https://openalex.org/keywords/chemotherapy-induced-cancer","display_name":"chemotherapy-induced cancer","score":0.6299999952316284},{"id":"https://openalex.org/keywords/molecular-pathogenesis","display_name":"molecular pathogenesis","score":0.8209999799728394},{"id":"https://openalex.org/keywords/clonal-hematopoiesis","display_name":"clonal hematopoiesis","score":0.9350000023841858},{"id":"https://openalex.org/keywords/bone-marrow-microenvironment","display_name":"bone marrow microenvironment","score":0.9769999980926514},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.8190000057220459},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.7670000195503235},{"id":"https://openalex.org/keywords/chemical-carcinogenesis","display_name":"chemical carcinogenesis","score":0.6830000281333923},{"id":"https://openalex.org/keywords/initiation-and-promotion","display_name":"initiation-promotion","score":0.8399999737739563},{"id":"https://openalex.org/keywords/risk-indicators","display_name":"risk indicators","score":0.5960000157356262},{"id":"https://openalex.org/keywords/genotoxic-drugs","display_name":"genotoxic drugs","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8264604210853577},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.6350690722465515},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5730863213539124},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5238021612167358},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5211398601531982},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5106208920478821},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.472545862197876},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4584185481071472},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4160362482070923},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.41360506415367126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3592550456523895},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:europepmc.org:6724729","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7811901","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7811901","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7811901","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Blood Res","raw_type":"Text"},{"id":"pmid:33489451","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33489451","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of blood research","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:6724729","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7811901","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":83,"referenced_works":["https://openalex.org/W269389925","https://openalex.org/W1781591963","https://openalex.org/W1799514218","https://openalex.org/W1951448021","https://openalex.org/W1969162338","https://openalex.org/W1974973003","https://openalex.org/W1977311715","https://openalex.org/W1985229938","https://openalex.org/W1991950992","https://openalex.org/W1994791499","https://openalex.org/W1997174802","https://openalex.org/W1998049167","https://openalex.org/W1998367819","https://openalex.org/W2002889467","https://openalex.org/W2015932379","https://openalex.org/W2016034318","https://openalex.org/W2035603238","https://openalex.org/W2044022462","https://openalex.org/W2044788671","https://openalex.org/W2044956722","https://openalex.org/W2045032252","https://openalex.org/W2047039095","https://openalex.org/W2053344338","https://openalex.org/W2054821489","https://openalex.org/W2056265113","https://openalex.org/W2058357603","https://openalex.org/W2065890382","https://openalex.org/W2077858999","https://openalex.org/W2079671151","https://openalex.org/W2091893762","https://openalex.org/W2098775844","https://openalex.org/W2114409684","https://openalex.org/W2123066843","https://openalex.org/W2127379731","https://openalex.org/W2130803751","https://openalex.org/W2133920348","https://openalex.org/W2141322180","https://openalex.org/W2148073787","https://openalex.org/W2149858388","https://openalex.org/W2155089093","https://openalex.org/W2157155777","https://openalex.org/W2162825929","https://openalex.org/W2163067447","https://openalex.org/W2166002104","https://openalex.org/W2172101787","https://openalex.org/W2175441324","https://openalex.org/W2179443225","https://openalex.org/W2192533162","https://openalex.org/W2313420578","https://openalex.org/W2471084888","https://openalex.org/W2520902851","https://openalex.org/W2557652172","https://openalex.org/W2563692456","https://openalex.org/W2570468391","https://openalex.org/W2590508855","https://openalex.org/W2594796471","https://openalex.org/W2607351395","https://openalex.org/W2738336818","https://openalex.org/W2739901926","https://openalex.org/W2745259295","https://openalex.org/W2749642104","https://openalex.org/W2767595816","https://openalex.org/W2768017473","https://openalex.org/W2784286628","https://openalex.org/W2785053083","https://openalex.org/W2792228267","https://openalex.org/W2884992117","https://openalex.org/W2888972748","https://openalex.org/W2897559733","https://openalex.org/W2899272142","https://openalex.org/W2900528911","https://openalex.org/W2902007051","https://openalex.org/W2905501602","https://openalex.org/W2911721699","https://openalex.org/W2912255647","https://openalex.org/W2913854915","https://openalex.org/W2931898234","https://openalex.org/W2945989190","https://openalex.org/W2965945224","https://openalex.org/W2967057123","https://openalex.org/W2980962161","https://openalex.org/W3006913409","https://openalex.org/W4297855306"],"related_works":["https://openalex.org/W2406753662","https://openalex.org/W1590909767","https://openalex.org/W7207248924","https://openalex.org/W2171300427","https://openalex.org/W2054592620","https://openalex.org/W2218524978","https://openalex.org/W4411464535","https://openalex.org/W3166724681","https://openalex.org/W2418444091","https://openalex.org/W4413050172"],"abstract_inverted_index":{"BACKGROUND:":[0],"Secondary":[1],"tumors,":[2],"including":[3],"therapy-related":[4],"acute":[5],"myeloid":[6],"leukemia":[7],"(t-AML),":[8],"represent":[9],"one":[10],"of":[11,17,38,74,90,123,130,134,156,167,176,179,190,205,207,211,229,243],"the":[12,32,47,54,79,97,103,109,116,135,154,160,174,191,203,208,223,227,241],"most":[13,98],"undesirable":[14],"side":[15],"effects":[16,166],"chemotherapy,":[18],"which":[19],"arise":[20],"several":[21],"years":[22],"after":[23],"primary":[24,124],"cancer":[25,72,125,194],"treatment.":[26],"This":[27],"review":[28,114],"aims":[29],"to":[30,46,52,221,237],"analyze":[31,53],"current":[33],"data":[34],"on":[35,56,169,173],"molecular":[36,121],"pathogenesis":[37,144],"t-AML":[39,60,67,119,143,150,185,235,247],"revealing":[40],"potential":[41,181],"criteria":[42],"for":[43,59,71,149,184,226,234,240,246],"predicting":[44],"predisposition":[45],"disease.":[48],"Another":[49],"objective":[50],"is":[51,145,200],"information":[55,117],"promising":[57],"approaches":[58,70,148],"prevention.":[61,186,248],"METHODS:":[62],"We":[63],"analyzed":[64],"studies":[65],"regarding":[66],"and":[68,88,142,158,172,216,236],"possible":[69,224],"prevention":[73,151],"drug-induced":[75],"tumors.":[76],"Publications":[77],"in":[78,102,139],"databases,":[80],"such":[81],"as":[82],"SciVerse":[83],"Scopus":[84],"(948),":[85],"PubMed":[86],"(1837)":[87],"Web":[89],"Science":[91],"(935)":[92],"were":[93,106],"used.":[94],"Among":[95],"92":[96],"important":[99],"publications":[100],"cited":[101],"review,":[104],"79":[105],"published":[107],"during":[108],"last":[110],"decade.":[111],"RESULTS:":[112],"The":[113,132,188],"provides":[115],"concerning":[118],"pathogenesis,":[120],"markers":[122,225],"patients":[126,230],"with":[127,231],"high":[128,232],"risk":[129,233],"t-AML.":[131],"role":[133],"bone":[136],"marrow":[137],"niche":[138],"clonal":[140],"hematopoiesis":[141],"discussed.":[146],"Current":[147],"both":[152],"at":[153,159],"stage":[155],"therapy":[157],"latent":[161],"period":[162],"are":[163,182],"described.":[164],"Inhibition":[165],"polyphenols":[168,245],"cell":[170],"proliferation":[171],"appearance":[175],"hemopoetic":[177],"clones":[178],"indeterminate":[180],"proposed":[183],"CONCLUSION:":[187],"problem":[189],"t-AML,":[192],"a":[193],"induced":[195],"by":[196],"genotoxic":[197],"chemotherapeutic":[198],"drugs,":[199],"considered":[201],"from":[202],"point":[204],"view":[206],"fundamental":[209],"mechanisms":[210],"chemical":[212],"carcinogenesis,":[213],"highlighting":[214],"initiation":[215],"promotion":[217],"stages.":[218],"It":[219],"enables":[220],"reveal":[222],"group":[228],"demonstrate":[238],"perspectives":[239],"use":[242],"plant":[244]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2021-02-01T00:00:00"}