{"id":"https://openalex.org/W3122929465","doi":"https://doi.org/10.1371/journal.pone.0236904","title":"Coffee consumption and risk of breast cancer: A Mendelian randomization study","display_name":"Coffee consumption and risk of breast cancer: A Mendelian randomization study","publication_year":2021,"publication_date":"2021-01-19","ids":{"openalex":"https://openalex.org/W3122929465","doi":"https://doi.org/10.1371/journal.pone.0236904","mag":"3122929465","pmid":"https://pubmed.ncbi.nlm.nih.gov/33465101","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7815134"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0236904","doi":"https://doi.org/10.1371/journal.pone.0236904","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0236904","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0236904&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0236904&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063508981","display_name":"Merete Ellingjord\u2010Dale","orcid":"https://orcid.org/0000-0001-9294-2510","observed_orcids":["https://orcid.org/0000-0001-9294-2510","https://orcid.org/0000-0003-2758-0140"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Merete Ellingjord-Dale","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018642626","display_name":"Nikos Papadimitriou","orcid":"https://orcid.org/0000-0001-8294-7262","observed_orcids":["https://orcid.org/0000-0001-8294-7262"]},"institutions":[{"id":"https://openalex.org/I42237331","display_name":"Centre international de recherche sur le cancer","ror":"https://ror.org/00v452281","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I42237331"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nikos Papadimitriou","raw_affiliation_strings":["Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France","institution_ids":["https://openalex.org/I42237331"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070112183","display_name":"Michail Katsoulis","orcid":"https://orcid.org/0000-0002-1756-9530","observed_orcids":["https://orcid.org/0000-0002-1756-9530"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michalis Katsoulis","raw_affiliation_strings":["Institute of Health Informatics Research, Faculty of Population Health Sciences, University College London, London, UK","Institute of Health Informatics Research, Faculty of Population Health Sciences, University College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Health Informatics Research, Faculty of Population Health Sciences, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Institute of Health Informatics Research, Faculty of Population Health Sciences, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033212855","display_name":"Chew Yee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chew Yee","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038804932","display_name":"Niki L. Dimou","orcid":"https://orcid.org/0000-0003-1678-9328","observed_orcids":["https://orcid.org/0000-0003-1678-9328"]},"institutions":[{"id":"https://openalex.org/I42237331","display_name":"Centre international de recherche sur le cancer","ror":"https://ror.org/00v452281","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210105654","https://openalex.org/I42237331"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Niki Dimou","raw_affiliation_strings":["Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France","institution_ids":["https://openalex.org/I42237331"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054061856","display_name":"Dipender Gill","orcid":"https://orcid.org/0000-0001-7312-7078","observed_orcids":["https://orcid.org/0000-0001-7312-7078"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dipender Gill","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0001-7312-7078","affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071060308","display_name":"Dagfinn Aune","orcid":"https://orcid.org/0000-0002-4533-1722","observed_orcids":["https://orcid.org/0000-0002-4533-1722"]},"institutions":[{"id":"https://openalex.org/I1281400175","display_name":"Oslo University Hospital","ror":"https://ror.org/00j9c2840","country_code":"NO","type":"healthcare","lineage":["https://openalex.org/I1281400175"]},{"id":"https://openalex.org/I4210128481","display_name":"Oslo Nye H\u00f8yskole","ror":"https://ror.org/030xrgd02","country_code":"NO","type":"education","lineage":["https://openalex.org/I4210128481"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB","NO"],"is_corresponding":false,"raw_author_name":"Dagfinn Aune","raw_affiliation_strings":["Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Nutrition, Bj\u00f8rknes University College, Oslo, Norway","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway","institution_ids":["https://openalex.org/I1281400175"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Nutrition, Bj\u00f8rknes University College, Oslo, Norway","institution_ids":["https://openalex.org/I4210128481"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064091669","display_name":"Jue\u2010Sheng Ong","orcid":"https://orcid.org/0000-0002-6062-710X","observed_orcids":["https://orcid.org/0000-0002-6062-710X"]},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["AU","GB"],"is_corresponding":false,"raw_author_name":"Jue-Sheng Ong","raw_affiliation_strings":["MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","Statistical Genetics, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]},{"raw_affiliation_string":"Statistical Genetics, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia","institution_ids":["https://openalex.org/I217937681"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029948119","display_name":"Stuart MacGregor","orcid":"https://orcid.org/0000-0001-6731-8142","observed_orcids":["https://orcid.org/0000-0001-6731-8142"]},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stuart MacGregor","raw_affiliation_strings":["Statistical Genetics, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Statistical Genetics, Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082222221","display_name":"Benjamin Elsworth","orcid":"https://orcid.org/0000-0001-7328-4233","observed_orcids":["https://orcid.org/0000-0001-7328-4233"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Benjamin Elsworth","raw_affiliation_strings":["MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003737642","display_name":"Sarah Jane Lewis","orcid":"https://orcid.org/0000-0003-4311-6890","observed_orcids":["https://orcid.org/0000-0003-4311-6890"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sarah J Lewis","raw_affiliation_strings":["Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]},{"raw_affiliation_string":"Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065571043","display_name":"Richard Michael Martin","orcid":"https://orcid.org/0000-0002-7992-7719","observed_orcids":["https://orcid.org/0000-0002-7992-7719"]},"institutions":[{"id":"https://openalex.org/I2800789647","display_name":"University Hospitals Bristol NHS Foundation Trust","ror":"https://ror.org/04nm1cv11","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800789647","https://openalex.org/I4392738148","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I34931013","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08","country_code":"GB","type":"government","lineage":["https://openalex.org/I34931013"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4210119147","display_name":"NIHR Bristol Biomedical Research Centre","ror":"https://ror.org/02mtt1z51","country_code":"GB","type":"facility","lineage":["https://openalex.org/I34931013","https://openalex.org/I4210119147","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard M Martin","raw_affiliation_strings":["Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, UK","Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom","MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom","National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I2800789647","https://openalex.org/I34931013","https://openalex.org/I36234482","https://openalex.org/I4210119147"]},{"raw_affiliation_string":"Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]},{"raw_affiliation_string":"National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom","institution_ids":["https://openalex.org/I2800789647","https://openalex.org/I34931013","https://openalex.org/I36234482","https://openalex.org/I4210119147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067228080","display_name":"Elio R\u00edboli","orcid":"https://orcid.org/0000-0001-6795-6080","observed_orcids":["https://orcid.org/0000-0001-6795-6080"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elio Riboli","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009120205","display_name":"Konstantinos K. Tsilidis","orcid":"https://orcid.org/0000-0002-8452-8472","observed_orcids":["https://orcid.org/0000-0002-8452-8472","https://orcid.org/0000-0002-2830-0596"]},"institutions":[{"id":"https://openalex.org/I194019607","display_name":"University of Ioannina","ror":"https://ror.org/01qg3j183","country_code":"GR","type":"education","lineage":["https://openalex.org/I194019607"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB","GR"],"is_corresponding":false,"raw_author_name":"Konstantinos K Tsilidis","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece","Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece","institution_ids":["https://openalex.org/I194019607"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5063508981"],"corresponding_institution_ids":["https://openalex.org/I47508984"],"apc_list":{"value":1749,"currency":"USD","value_usd":1749},"apc_paid":{"value":1749,"currency":"USD","value_usd":1749},"fwci":2.2522,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.86600913,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"16","issue":"1","first_page":"e0236904","last_page":"e0236904"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.039900001138448715,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coffee-consumption","display_name":"coffee consumption","score":1.0},{"id":"https://openalex.org/keywords/breast-cancer-risk","display_name":"breast cancer risk","score":0.9309999942779541},{"id":"https://openalex.org/keywords/estrogen-receptor-positive-breast-cancer","display_name":"estrogen receptor-positive breast cancer","score":0.9210000038146973},{"id":"https://openalex.org/keywords/estrogen-receptor-negative-breast-cancer","display_name":"estrogen receptor-negative breast cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9570000171661377},{"id":"https://openalex.org/keywords/protective-association","display_name":"protective association","score":0.328000009059906},{"id":"https://openalex.org/keywords/women-s-health","display_name":"women's health","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7980976700782776},{"id":"https://openalex.org/C2779901538","wikidata":"https://www.wikidata.org/wiki/Q6816584","display_name":"Mendelian randomization","level":5,"score":0.7862052321434021},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6865441203117371},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6180105209350586},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6073541045188904},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5808137059211731},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5506439208984375},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.47182828187942505},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.45390334725379944},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.42438894510269165},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.41077014803886414},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.397394061088562},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22332730889320374},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.21403643488883972},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17860430479049683},{"id":"https://openalex.org/C2993967602","wikidata":"https://www.wikidata.org/wiki/Q5532932","display_name":"Genetic variants","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003069","descriptor_name":"Coffee","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057182","descriptor_name":"Mendelian Randomization Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":12,"locations":[{"id":"doi:10.1371/journal.pone.0236904","doi":"https://doi.org/10.1371/journal.pone.0236904","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0236904","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0236904&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"doi:10.1101/2020.07.17.208421","doi":"https://doi.org/10.1101/2020.07.17.208421","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2020.07.17.208421","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2020/07/17/2020.07.17.208421.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:6745970","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7815134","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7815134","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7815134","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:33465101","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33465101","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:openaccess.sgul.ac.uk:112856","doi":null,"is_oa":false,"landing_page_url":"https://openaccess.sgul.ac.uk/id/eprint/112856/3/journal.pone.0236904.pdf","pdf_url":"https://openaccess.sgul.ac.uk/id/eprint/112856/3/journal.pone.0236904.pdf","source":{"id":"https://openalex.org/S4306400552","display_name":"St George's Online Research Archive (St George's University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165862685","host_organization_name":"St George's, University of London","host_organization_lineage":["https://openalex.org/I165862685"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:research-information.bris.ac.uk:publications/fc667b81-d270-49a9-a011-1c164b8c1d8a","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1983/fc667b81-d270-49a9-a011-1c164b8c1d8a","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ellingjord-Dale, M, Papadimitriou, N, Ong, J S, Elsworth, B L, Lewis, S J & Martin, R M 2021, 'Coffee consumption and risk of breast cancer : a Mendelian Randomization study ', PLOS ONE, vol. 16, no. 1, e0236904. https://doi.org/10.1371/journal.pone.0236904","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:RePEc:plo:pone00:0236904","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0236904","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:5de0d9dcf17c44c0be69d9610ff2f7a3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5de0d9dcf17c44c0be69d9610ff2f7a3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 16, Iss 1, p e0236904 (2021)","raw_type":"article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10119937","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10119937/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLOS ONE , 16 (1) , Article e0236904. (2021)","raw_type":"Article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/fc667b81-d270-49a9-a011-1c164b8c1d8a","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/files/263286887/journal.pone.0236904.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ellingjord-Dale, M, Papadimitriou, N, Ong, J S, Elsworth, B L, Lewis, S J & Martin, R M 2021, 'Coffee consumption and risk of breast cancer : a Mendelian Randomization study ', PLOS ONE, vol. 16, no. 1, e0236904. https://doi.org/10.1371/journal.pone.0236904","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/86503","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/86503","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0236904","doi":"https://doi.org/10.1371/journal.pone.0236904","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0236904","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0236904&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G104449235","display_name":null,"funder_award_id":"2014/1180","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"},{"id":"https://openalex.org/G1131969086","display_name":null,"funder_award_id":"C18281/","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1389895161","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G149876332","display_name":null,"funder_award_id":"MC_UU_12013/1","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G1614944260","display_name":null,"funder_award_id":"PSR-SIIRI-701","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G173885373","display_name":null,"funder_award_id":"C18281/A19169","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G1955001954","display_name":null,"funder_award_id":"MC_UU_12013_2","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G1987169411","display_name":null,"funder_award_id":"MC_UU_12013/3","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G2293058991","display_name":null,"funder_award_id":"2014/1180","funder_id":"https://openalex.org/F4320314489","funder_display_name":"World Cancer Research Fund International"},{"id":"https://openalex.org/G235045266","display_name":null,"funder_award_id":"MC_UU_12013","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2531246262","display_name":"Discovery, Biology and Risk of Inherited Variants in Breast Cancer","funder_award_id":"U19CA148065","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2642749895","display_name":null,"funder_award_id":"C18281/A19169","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G2809956348","display_name":null,"funder_award_id":"29019","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G301055538","display_name":null,"funder_award_id":"MC_UU_12013/1","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G3217467674","display_name":null,"funder_award_id":"WCRF 2014/1180","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"},{"id":"https://openalex.org/G3288244108","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"},{"id":"https://openalex.org/G3344456887","display_name":null,"funder_award_id":"C18281 / A19169","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G3385934250","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320319880","funder_display_name":"Government of Canada"},{"id":"https://openalex.org/G3718558835","display_name":null,"funder_award_id":"PSR-SIIRI-701","funder_id":"https://openalex.org/F4320334633","funder_display_name":"World Cancer Research Fund"},{"id":"https://openalex.org/G3807225764","display_name":null,"funder_award_id":"PSR-SIIRI-701","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G3830541857","display_name":null,"funder_award_id":"PSR-SIIRI-701","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4339904293","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G476489484","display_name":null,"funder_award_id":"PSRSIIRI-701","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4807506537","display_name":null,"funder_award_id":"MC_UU_12013/1, MC_UU_12013/2","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5001017760","display_name":null,"funder_award_id":"MCUU12013/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5181373253","display_name":null,"funder_award_id":"PSR-SIIRI-701","funder_id":"https://openalex.org/F4320319880","funder_display_name":"Government of Canada"},{"id":"https://openalex.org/G5331993534","display_name":"UK Biobank (core renewal)","funder_award_id":"MC_PC_17228","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5747748742","display_name":null,"funder_award_id":"WCRF 2014/1180","funder_id":"https://openalex.org/F4320314489","funder_display_name":"World Cancer Research Fund International"},{"id":"https://openalex.org/G6119919417","display_name":null,"funder_award_id":"MC_UU_12013","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G6370857267","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6423108142","display_name":null,"funder_award_id":"MC_UU_12013/3","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6682065591","display_name":null,"funder_award_id":"A19169","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6856032400","display_name":"Mendelian randomization to hypothesis-free causal inference","funder_award_id":"MC_UU_00011/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6971553973","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320310787","funder_display_name":"Genome Canada"},{"id":"https://openalex.org/G738105237","display_name":null,"funder_award_id":"MC_UU_12013/2","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G76752795","display_name":null,"funder_award_id":"19169","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G7698318594","display_name":null,"funder_award_id":"C18281/A19169","funder_id":"https://openalex.org/F4320314489","funder_display_name":"World Cancer Research Fund International"},{"id":"https://openalex.org/G829717837","display_name":null,"funder_award_id":"PSRSIIRI-701","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G8668082143","display_name":null,"funder_award_id":"U19 CA148065","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G8732842755","display_name":"Weight change and the onset and progression of cardiovascular diseases in large-scale electronic health records","funder_award_id":"FS/18/5/33319","funder_id":"https://openalex.org/F4320319992","funder_display_name":"British Heart Foundation"}],"funders":[{"id":"https://openalex.org/F4320307856","display_name":"World Health Organization","ror":"https://ror.org/01f80g185"},{"id":"https://openalex.org/F4320310728","display_name":"Centre International de Recherche sur le Cancer","ror":"https://ror.org/00v452281"},{"id":"https://openalex.org/F4320310787","display_name":"Genome Canada","ror":"https://ror.org/029s29983"},{"id":"https://openalex.org/F4320313311","display_name":"University Hospitals Bristol NHS Foundation Trust","ror":"https://ror.org/04nm1cv11"},{"id":"https://openalex.org/F4320314489","display_name":"World Cancer Research Fund International","ror":"https://ror.org/02747h926"},{"id":"https://openalex.org/F4320319880","display_name":"Government of Canada","ror":"https://ror.org/010q4q527"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319992","display_name":"British Heart Foundation","ror":"https://ror.org/02wdwnk04"},{"id":"https://openalex.org/F4320320360","display_name":"University of Bristol","ror":"https://ror.org/0524sp257"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334633","display_name":"World Cancer Research Fund","ror":"https://ror.org/02gc7qc02"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3122929465.pdf","grobid_xml":"https://content.openalex.org/works/W3122929465.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W1519566581","https://openalex.org/W1869213955","https://openalex.org/W1902575419","https://openalex.org/W1904407543","https://openalex.org/W1905058580","https://openalex.org/W1960017990","https://openalex.org/W1966775465","https://openalex.org/W1969247437","https://openalex.org/W1974416404","https://openalex.org/W1975043150","https://openalex.org/W1976844911","https://openalex.org/W1994477228","https://openalex.org/W1997344933","https://openalex.org/W2002752091","https://openalex.org/W2008667751","https://openalex.org/W2015411601","https://openalex.org/W2022789178","https://openalex.org/W2045474458","https://openalex.org/W2048307994","https://openalex.org/W2054306441","https://openalex.org/W2054667879","https://openalex.org/W2064317825","https://openalex.org/W2079195789","https://openalex.org/W2082704080","https://openalex.org/W2094640736","https://openalex.org/W2102325625","https://openalex.org/W2103783427","https://openalex.org/W2103934508","https://openalex.org/W2104382557","https://openalex.org/W2105148050","https://openalex.org/W2106094885","https://openalex.org/W2109017223","https://openalex.org/W2109906720","https://openalex.org/W2112203259","https://openalex.org/W2113506041","https://openalex.org/W2113699335","https://openalex.org/W2120181458","https://openalex.org/W2125537737","https://openalex.org/W2126027581","https://openalex.org/W2129465958","https://openalex.org/W2133270744","https://openalex.org/W2135895196","https://openalex.org/W2141311529","https://openalex.org/W2145748250","https://openalex.org/W2147245308","https://openalex.org/W2147311167","https://openalex.org/W2150841439","https://openalex.org/W2151355802","https://openalex.org/W2153117775","https://openalex.org/W2155441570","https://openalex.org/W2164338752","https://openalex.org/W2166267940","https://openalex.org/W2171240833","https://openalex.org/W2224996358","https://openalex.org/W2257575740","https://openalex.org/W2258352733","https://openalex.org/W2277017932","https://openalex.org/W2307618641","https://openalex.org/W2324862792","https://openalex.org/W2501176776","https://openalex.org/W2508534964","https://openalex.org/W2509847565","https://openalex.org/W2529485316","https://openalex.org/W2563060873","https://openalex.org/W2604218568","https://openalex.org/W2612427157","https://openalex.org/W2613603864","https://openalex.org/W2622693920","https://openalex.org/W2765253743","https://openalex.org/W2777667999","https://openalex.org/W2789138430","https://openalex.org/W2803072880","https://openalex.org/W2818417770","https://openalex.org/W2884028796","https://openalex.org/W2905226148","https://openalex.org/W2909486692","https://openalex.org/W2909598358","https://openalex.org/W2933157483","https://openalex.org/W2952494466","https://openalex.org/W2959202078","https://openalex.org/W2965887611","https://openalex.org/W4230866720","https://openalex.org/W4245432335","https://openalex.org/W4300308899"],"related_works":["https://openalex.org/W4306679944","https://openalex.org/W7162772539","https://openalex.org/W2772598231","https://openalex.org/W2959202078","https://openalex.org/W4293092582","https://openalex.org/W4403943183","https://openalex.org/W4206993282","https://openalex.org/W4388684177","https://openalex.org/W3180266685","https://openalex.org/W4415019734"],"abstract_inverted_index":{"BACKGROUND:":[0],"Observational":[1],"studies":[2],"have":[3],"reported":[4],"either":[5],"null":[6],"or":[7],"weak":[8,246],"protective":[9],"associations":[10,184],"for":[11,66,159],"coffee":[12,33,46,134,232],"consumption":[13,34,47,135,233],"and":[14,35,96,172,209],"risk":[15,38,142],"of":[16,60,99,120,143,219,229,244],"breast":[17,36,67,174,195,235],"cancer.":[18],"METHODS:":[19],"We":[20],"conducted":[21],"a":[22,49,245],"two-sample":[23],"Mendelian":[24],"randomization":[25],"(MR)":[26],"analysis":[27],"to":[28,116],"evaluate":[29],"the":[30,78,118,189],"relationship":[31],"between":[32],"cancer":[37,68,175,236],"using":[39,192],"33":[40],"single-nucleotide":[41],"polymorphisms":[42],"(SNPs)":[43],"associated":[44,140],"with":[45,112,141],"from":[48,71,77],"genome-wide":[50],"association":[51,228],"(GWA)":[52],"study":[53,223],"on":[54,84,234],"212,119":[55],"female":[56],"UK":[57],"Biobank":[58],"participants":[59],"White":[61],"British":[62],"ancestry.":[63,101],"Risk":[64],"estimates":[65],"were":[69,90,109,185],"retrieved":[70],"publicly":[72],"available":[73],"GWA":[74],"summary":[75],"statistics":[76],"Breast":[79],"Cancer":[80],"Association":[81],"Consortium":[82],"(BCAC)":[83],"122,977":[85],"cases":[86],"(of":[87],"which":[88],"69,501":[89],"estrogen":[91],"receptor":[92],"(ER)-positive,":[93],"21,468":[94],"ER-negative)":[95],"105,974":[97],"controls":[98],"European":[100],"Random-effects":[102],"inverse":[103],"variance":[104],"weighted":[105,202,210],"(IVW)":[106],"MR":[107,122,222],"analyses":[108,115,191],"performed":[110],"along":[111],"several":[113],"sensitivity":[114,190],"assess":[117],"impact":[119],"potential":[121],"assumption":[123],"violations.":[124],"RESULTS:":[125],"One":[126],"cup":[127],"per":[128],"day":[129],"increase":[130],"in":[131,136,188],"genetically":[132,230],"predicted":[133,231],"women":[137],"was":[138],"not":[139,225],"total":[144],"(IVW":[145],"random-effects;":[146],"odds":[147],"ratio":[148],"(OR):":[149],"0.91,":[150],"95%":[151,167,178,199,206],"confidence":[152],"intervals":[153],"(CI):":[154],"0.80-1.02,":[155],"P:":[156,170,181],"0.12,":[157],"P":[158],"instrument":[160],"heterogeneity:":[161],"7.17e-13),":[162],"ER-positive":[163],"(OR":[164],"=":[165],"0.90,":[166],"CI:":[168,179,200,207,214],"0.79-1.02,":[169],"0.09)":[171],"ER-negative":[173],"(OR:":[176,204,212],"0.88,":[177],"0.75-1.03,":[180],"0.12).":[182],"Null":[183],"also":[186],"found":[187],"MR-Egger":[193],"(total":[194],"cancer;":[196],"OR:":[197],"1.00,":[198,213],"0.80-1.25),":[201],"median":[203],"0.97,":[205],"0.89-1.05)":[208],"mode":[211],"0.93-1.07).":[215],"CONCLUSIONS:":[216],"The":[217],"results":[218],"this":[220],"large":[221],"do":[224],"support":[226],"an":[227],"risk,":[237],"but":[238],"we":[239],"cannot":[240],"rule":[241],"out":[242],"existence":[243],"association.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2021-02-01T00:00:00"}