{"id":"https://openalex.org/W3122055007","doi":"https://doi.org/10.1201/9781003048237-5","title":"Viruses as vectors for the delivery of gene-editing reagents","display_name":"Viruses as vectors for the delivery of gene-editing reagents","publication_year":2021,"publication_date":"2021-01-18","ids":{"openalex":"https://openalex.org/W3122055007","doi":"https://doi.org/10.1201/9781003048237-5","mag":"3122055007"},"language":"en","primary_location":{"id":"doi:10.19103/as.2020.0082.28","doi":"https://doi.org/10.19103/as.2020.0082.28","is_oa":false,"landing_page_url":"https://doi.org/10.19103/as.2020.0082.28","pdf_url":null,"source":{"id":"https://openalex.org/S4210185699","display_name":"Burleigh Dodds series in agricultural science","issn_l":"2059-6936","issn":["2059-6936","2059-6944"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4365333985","host_organization_name":"Burleigh Dodds Science Publishing Limited","host_organization_lineage":["https://openalex.org/P4365333985"],"host_organization_lineage_names":["Burleigh Dodds Science Publishing Limited"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Burleigh Dodds Series in Agricultural Science","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4253559147","display_name":"Genome editing for precision crop breeding"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://directory.doabooks.org/handle/20.500.12854/97824","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083994191","display_name":"Evan E. Ellison","orcid":"https://orcid.org/0000-0003-3345-6429","observed_orcids":["https://orcid.org/0000-0003-3345-6429"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan E. Ellison","raw_affiliation_strings":["University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021395116","display_name":"James C. Chamness","orcid":"https://orcid.org/0000-0001-8862-0236","observed_orcids":["https://orcid.org/0000-0001-8862-0236"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James C. Chamness","raw_affiliation_strings":["University of Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Minnesota, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049418431","display_name":"Daniel F. Voytas","orcid":"https://orcid.org/0000-0002-4944-1224","observed_orcids":["https://orcid.org/0000-0002-4944-1224"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel F. Voytas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.8031,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.94058044,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"97","last_page":"122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.30079999566078186,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.30079999566078186,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.2921999990940094,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.2685999870300293,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plant-viruses","display_name":"plant viruses","score":0.609000027179718},{"id":"https://openalex.org/keywords/viral-vectors","display_name":"viral vectors","score":0.9570000171661377},{"id":"https://openalex.org/keywords/genome-editing","display_name":"genome editing","score":0.7710000276565552},{"id":"https://openalex.org/keywords/plant-rna-viruses","display_name":"plant RNA viruses","score":0.9739999771118164},{"id":"https://openalex.org/keywords/heritable-genetic-modification","display_name":"heritable genetic modification","score":0.6840000152587891},{"id":"https://openalex.org/keywords/germline-genome-editing","display_name":"germline editing","score":0.6859999895095825},{"id":"https://openalex.org/keywords/plant-transformation","display_name":"plant transformation","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C144501496","wikidata":"https://www.wikidata.org/wiki/Q5533489","display_name":"Genome editing","level":4,"score":0.7042948007583618},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6903929710388184},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6430206298828125},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5528441071510315},{"id":"https://openalex.org/C135983454","wikidata":"https://www.wikidata.org/wiki/Q2790163","display_name":"Gene delivery","level":4,"score":0.5437319278717041},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.47282111644744873},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4401310682296753},{"id":"https://openalex.org/C189819185","wikidata":"https://www.wikidata.org/wiki/Q384283","display_name":"Subgenomic mRNA","level":4,"score":0.4167832136154175},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3888745605945587},{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.3786255717277527},{"id":"https://openalex.org/C111599444","wikidata":"https://www.wikidata.org/wiki/Q213901","display_name":"Genetic enhancement","level":3,"score":0.289630651473999}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.19103/as.2020.0082.28","doi":"https://doi.org/10.19103/as.2020.0082.28","is_oa":false,"landing_page_url":"https://doi.org/10.19103/as.2020.0082.28","pdf_url":null,"source":{"id":"https://openalex.org/S4210185699","display_name":"Burleigh Dodds series in agricultural science","issn_l":"2059-6936","issn":["2059-6936","2059-6944"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4365333985","host_organization_name":"Burleigh Dodds Science Publishing Limited","host_organization_lineage":["https://openalex.org/P4365333985"],"host_organization_lineage_names":["Burleigh Dodds Science Publishing Limited"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Burleigh Dodds Series in Agricultural Science","raw_type":"book-chapter"},{"id":"doi:10.1201/9781003048237-5","doi":"https://doi.org/10.1201/9781003048237-5","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9781003048237-5","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome editing for precision crop breeding","raw_type":"book-chapter"},{"id":"pmh:oai:directory.doabooks.org:20.500.12854/97824","doi":null,"is_oa":true,"landing_page_url":"https://directory.doabooks.org/handle/20.500.12854/97824","pdf_url":null,"source":{"id":"https://openalex.org/S4306400539","display_name":"Directory of Open access Books (OAPEN Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4387153118","host_organization_name":"OAPEN Foundation","host_organization_lineage":["https://openalex.org/I4387153118"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:directory.doabooks.org:20.500.12854/97824","doi":null,"is_oa":true,"landing_page_url":"https://directory.doabooks.org/handle/20.500.12854/97824","pdf_url":null,"source":{"id":"https://openalex.org/S4306400539","display_name":"Directory of Open access Books (OAPEN Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4387153118","host_organization_name":"OAPEN Foundation","host_organization_lineage":["https://openalex.org/I4387153118"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W106783840","https://openalex.org/W1236282760","https://openalex.org/W1498209041","https://openalex.org/W1541869599","https://openalex.org/W1550686355","https://openalex.org/W1555618245","https://openalex.org/W1835708631","https://openalex.org/W1965672788","https://openalex.org/W1972168453","https://openalex.org/W1985779772","https://openalex.org/W1994150718","https://openalex.org/W1998350048","https://openalex.org/W2008573905","https://openalex.org/W2010260179","https://openalex.org/W2019798878","https://openalex.org/W2022187444","https://openalex.org/W2043198157","https://openalex.org/W2045435533","https://openalex.org/W2053228735","https://openalex.org/W2054899302","https://openalex.org/W2057563780","https://openalex.org/W2068066258","https://openalex.org/W2075798313","https://openalex.org/W2076194872","https://openalex.org/W2078586926","https://openalex.org/W2082720258","https://openalex.org/W2083309547","https://openalex.org/W2087646800","https://openalex.org/W2090614579","https://openalex.org/W2093281273","https://openalex.org/W2105299972","https://openalex.org/W2112444085","https://openalex.org/W2123531953","https://openalex.org/W2133872029","https://openalex.org/W2135008913","https://openalex.org/W2138835651","https://openalex.org/W2140833808","https://openalex.org/W2141225945","https://openalex.org/W2146611372","https://openalex.org/W2148302985","https://openalex.org/W2148467925","https://openalex.org/W2149058703","https://openalex.org/W2150798416","https://openalex.org/W2158357429","https://openalex.org/W2163868178","https://openalex.org/W2164527203","https://openalex.org/W2166453468","https://openalex.org/W2178477749","https://openalex.org/W2415866436","https://openalex.org/W2418701854","https://openalex.org/W2492321596","https://openalex.org/W2518482056","https://openalex.org/W2549111871","https://openalex.org/W2594683972","https://openalex.org/W2595015883","https://openalex.org/W2595220198","https://openalex.org/W2598674316","https://openalex.org/W2606565969","https://openalex.org/W2616302079","https://openalex.org/W2759479543","https://openalex.org/W2765211543","https://openalex.org/W2806398251","https://openalex.org/W2914085251","https://openalex.org/W2944768091","https://openalex.org/W2949656550","https://openalex.org/W2981137429","https://openalex.org/W2990759783","https://openalex.org/W3037978928"],"related_works":["https://openalex.org/W4396721212","https://openalex.org/W7204850519","https://openalex.org/W4411196250","https://openalex.org/W7162780936","https://openalex.org/W3153407713","https://openalex.org/W4388866475","https://openalex.org/W4409681776","https://openalex.org/W4405693180","https://openalex.org/W4402581630","https://openalex.org/W4319777701"],"abstract_inverted_index":{"A":[0],"significant":[1],"challenge":[2],"for":[3,55,74,88,107,117],"plant":[4,63],"gene":[5,77,101],"editing":[6,11,42,78],"is":[7,29],"the":[8,108],"delivery":[9,24,75],"of":[10,36,76,84,110],"reagents":[12],"to":[13,18,68,96],"germline":[14],"or":[15,27,43,70,116],"regenerable":[16],"cells":[17],"recover":[19],"heritable":[20],"genetic":[21],"modifications.":[22],"Reagent":[23],"using":[25,94],"biolistics":[26],"Agrobacterium":[28],"only":[30],"possible":[31],"with":[32],"a":[33],"limited":[34],"range":[35],"species":[37],"and":[38,40,58,61,103,129,134],"genotypes,":[39],"inefficient":[41],"lengthy":[44],"tissue":[45],"culture":[46],"steps":[47],"further":[48],"limit":[49],"throughput.":[50],"Viruses":[51],"are":[52,137],"natural":[53],"vectors":[54,73,112],"nucleic":[56],"acids,":[57],"both":[59,125],"DNA":[60,133],"RNA":[62,135],"viruses":[64,95,136],"have":[65],"been":[66],"engineered":[67],"extend":[69],"replace":[71],"conventional":[72],"reagents.":[79],"Here,":[80],"we":[81],"review":[82],"aspects":[83],"viral":[85,111],"biology":[86],"essential":[87],"engineering":[89],"vectors,":[90,132],"highlight":[91],"landmark":[92],"studies":[93],"overcome":[97],"traditional":[98],"limitations":[99],"in":[100,113,124],"editing,":[102],"outline":[104],"important":[105],"considerations":[106],"use":[109],"new":[114,118],"systems":[115],"targets.":[119],"Motivated":[120],"by":[121],"fundamental":[122],"differences":[123],"their":[126],"infection":[127],"modes":[128],"utility":[130],"as":[131],"treated":[138],"separately.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-02-01T00:00:00"}