{"id":"https://openalex.org/W3121908161","doi":"https://doi.org/10.5546/aap.2021.e65","title":"Tratamiento con propranolol en el s\u00edndrome de Kasabach-Merritt secundario a hemangioma hep\u00e1tico cong\u00e9nito. Caso cl\u00ednico","display_name":"Tratamiento con propranolol en el s\u00edndrome de Kasabach-Merritt secundario a hemangioma hep\u00e1tico cong\u00e9nito. Caso cl\u00ednico","publication_year":2021,"publication_date":"2021-01-13","ids":{"openalex":"https://openalex.org/W3121908161","doi":"https://doi.org/10.5546/aap.2021.e65","mag":"3121908161","pmid":"https://pubmed.ncbi.nlm.nih.gov/33458995"},"language":"es","primary_location":{"id":"doi:10.5546/aap.2021.e65","doi":"https://doi.org/10.5546/aap.2021.e65","is_oa":true,"landing_page_url":"https://doi.org/10.5546/aap.2021.e65","pdf_url":"https://doi.org/10.5546/aap.2021.e65","source":{"id":"https://openalex.org/S387551","display_name":"Archivos Argentinos de Pediatria","issn_l":"0325-0075","issn":["0325-0075","1668-3501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","medline","nbra","norway-1","poland-20","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4320800705","host_organization_name":"Sociedad Argentina de Pediatr\u00eda","host_organization_lineage":["https://openalex.org/P4320800705"],"host_organization_lineage_names":["Sociedad Argentina de Pediatr\u00eda"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos Argentinos de Pediatria","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3121908161"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5546/aap.2021.e65","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074568963","display_name":"Erika M Selzer Soria","orcid":"https://orcid.org/0000-0002-9239-9236","observed_orcids":["https://orcid.org/0000-0002-9239-9236"]},"institutions":[{"id":"https://openalex.org/I4210099959","display_name":"Hospital Universitario Austral","ror":"https://ror.org/014nx0w70","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210099959"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Erika M Selzer Soria","raw_affiliation_strings":["Secci\u00f3n Hepatolog\u00eda Infantil y Trasplante Hep\u00e1tico, Hospital Universitario Austral, Pilar, provincia de Buenos Aires, Argentina. erikaselzer2@yahoo.com.ar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secci\u00f3n Hepatolog\u00eda Infantil y Trasplante Hep\u00e1tico, Hospital Universitario Austral, Pilar, provincia de Buenos Aires, Argentina. erikaselzer2@yahoo.com.ar","institution_ids":["https://openalex.org/I4210099959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062028387","display_name":"Ivone Malla","orcid":"https://orcid.org/0000-0001-8427-5287","observed_orcids":["https://orcid.org/0000-0001-8427-5287"]},"institutions":[{"id":"https://openalex.org/I4210099959","display_name":"Hospital Universitario Austral","ror":"https://ror.org/014nx0w70","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210099959"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Ivone Malla","raw_affiliation_strings":["Secci\u00f3n Hepatolog\u00eda Infantil y Trasplante Hep\u00e1tico, Hospital Universitario Austral, Pilar, provincia de Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Secci\u00f3n Hepatolog\u00eda Infantil y Trasplante Hep\u00e1tico, Hospital Universitario Austral, Pilar, provincia de Buenos Aires, Argentina","institution_ids":["https://openalex.org/I4210099959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210099959"],"apc_list":null,"apc_paid":null,"fwci":0.2253,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.44071708,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"119","issue":"1","first_page":"e65","last_page":"e69"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13878","display_name":"Case Reports on Hematomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kasai-merritt-syndrome","display_name":"Kasai-Merritt syndrome","score":0.9369999766349792},{"id":"https://openalex.org/keywords/hepatic-hemangioma","display_name":"hepatic hemangioma","score":0.8510000109672546},{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":0.9559999704360962},{"id":"https://openalex.org/keywords/newborns","display_name":"neonates","score":0.5929999947547913},{"id":"https://openalex.org/keywords/infantile-hemangioma","display_name":"infantile hemangioma","score":0.843999981880188},{"id":"https://openalex.org/keywords/doppler-ultrasound","display_name":"Doppler ultrasound","score":0.8420000076293945},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9075049161911011},{"id":"https://openalex.org/C2779401007","wikidata":"https://www.wikidata.org/wiki/Q764185","display_name":"Kasabach\u2013Merritt syndrome","level":3,"score":0.7746856212615967},{"id":"https://openalex.org/C2778151854","wikidata":"https://www.wikidata.org/wiki/Q423364","display_name":"Propranolol","level":2,"score":0.6681369543075562},{"id":"https://openalex.org/C2776304256","wikidata":"https://www.wikidata.org/wiki/Q1607658","display_name":"Hepatoblastoma","level":2,"score":0.6594529151916504},{"id":"https://openalex.org/C2780191036","wikidata":"https://www.wikidata.org/wiki/Q861028","display_name":"Hemangioma","level":2,"score":0.5386748909950256},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.51050865650177},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3270907998085022},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2416881024837494},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14035069942474365}],"mesh":[{"descriptor_ui":"D006391","descriptor_name":"Hemangioma","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006391","descriptor_name":"Hemangioma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011433","descriptor_name":"Propranolol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D059885","descriptor_name":"Kasabach-Merritt Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D059885","descriptor_name":"Kasabach-Merritt Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.5546/aap.2021.e65","doi":"https://doi.org/10.5546/aap.2021.e65","is_oa":true,"landing_page_url":"https://doi.org/10.5546/aap.2021.e65","pdf_url":"https://doi.org/10.5546/aap.2021.e65","source":{"id":"https://openalex.org/S387551","display_name":"Archivos Argentinos de Pediatria","issn_l":"0325-0075","issn":["0325-0075","1668-3501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","medline","nbra","norway-1","poland-20","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4320800705","host_organization_name":"Sociedad Argentina de Pediatr\u00eda","host_organization_lineage":["https://openalex.org/P4320800705"],"host_organization_lineage_names":["Sociedad Argentina de Pediatr\u00eda"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos Argentinos de Pediatria","raw_type":"journal-article"},{"id":"pmid:33458995","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33458995","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos argentinos de pediatria","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.5546/aap.2021.e65","doi":"https://doi.org/10.5546/aap.2021.e65","is_oa":true,"landing_page_url":"https://doi.org/10.5546/aap.2021.e65","pdf_url":"https://doi.org/10.5546/aap.2021.e65","source":{"id":"https://openalex.org/S387551","display_name":"Archivos Argentinos de Pediatria","issn_l":"0325-0075","issn":["0325-0075","1668-3501"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","medline","nbra","norway-1","poland-20","russia-white-list-3","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4320800705","host_organization_name":"Sociedad Argentina de Pediatr\u00eda","host_organization_lineage":["https://openalex.org/P4320800705"],"host_organization_lineage_names":["Sociedad Argentina de Pediatr\u00eda"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archivos Argentinos de Pediatria","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3121908161.pdf","grobid_xml":"https://content.openalex.org/works/W3121908161.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1592332231","https://openalex.org/W2064555053","https://openalex.org/W2100584705","https://openalex.org/W2525918371","https://openalex.org/W2571248324","https://openalex.org/W2591248956","https://openalex.org/W2809279664","https://openalex.org/W2890229006","https://openalex.org/W2980630409"],"related_works":["https://openalex.org/W2605615971","https://openalex.org/W7171267728","https://openalex.org/W2596438690","https://openalex.org/W1494373341","https://openalex.org/W2420689166","https://openalex.org/W3143509337","https://openalex.org/W1529871441","https://openalex.org/W1947484205","https://openalex.org/W2766065190","https://openalex.org/W2736451417"],"abstract_inverted_index":{"Hepatic":[0],"hemangioma":[1,93],"is":[2,56],"the":[3,70,85],"most":[4],"common":[5],"benign":[6],"liver":[7],"tumor.":[8],"It":[9],"can":[10],"be":[11],"congenital":[12],"or":[13,35],"infantile":[14],"with":[15,29,58,74,90,97],"different":[16],"outcomes":[17],"and":[18,43,48,77,94,101],"complications.":[19],"The":[20],"clinical":[21],"manifestation":[22],"varies":[23],"from":[24],"asymptomatic":[25],"to":[26,103],"severe":[27],"conditions":[28],"heart":[30],"failure,":[31],"Kasabach-":[32],"Merritt":[33],"syndrome":[34,96],"compartment":[36],"syndrome.":[37],"Diagnosis":[38],"depends":[39],"on":[40],"medical":[41],"history":[42],"imaging":[44],"studies,":[45],"especially":[46],"ultrasound":[47],"Doppler":[49],"examination":[50],"in":[51],"experienced":[52],"hands.":[53],"Differential":[54],"diagnosis":[55],"essential":[57],"other":[59],"hepatic":[60,92],"lesions,":[61],"mainly":[62],"hepatoblastoma.":[63],"In":[64],"symptomatic":[65],"patients,":[66],"propranolol":[67],"emerges":[68],"as":[69],"first":[71],"line":[72],"treatment":[73],"good":[75],"results":[76],"low":[78],"frequency":[79],"of":[80,87],"adverse":[81],"effects.":[82],"We":[83],"present":[84],"case":[86],"a":[88,91],"newborn":[89],"Kasabach-Merritt":[95],"an":[98],"excellent":[99],"response":[100],"tolerance":[102],"propranolol.":[104]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2021-02-01T00:00:00"}