{"id":"https://openalex.org/W3121612403","doi":"https://doi.org/10.2139/ssrn.3387689","title":"Wnt7a-Releasing Synthetic Hydrogel Enhances Local Skeletal Muscle Regeneration and Muscle Stem Cell Engraftment","display_name":"Wnt7a-Releasing Synthetic Hydrogel Enhances Local Skeletal Muscle Regeneration and Muscle Stem Cell Engraftment","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W3121612403","doi":"https://doi.org/10.2139/ssrn.3387689","mag":"3121612403"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.3387689","doi":"https://doi.org/10.2139/ssrn.3387689","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3387689","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.3387689","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060807441","display_name":"Woojin M. Han","orcid":"https://orcid.org/0000-0002-1383-5686","observed_orcids":["https://orcid.org/0000-0002-1383-5686"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Woojin M. Han","raw_affiliation_strings":["Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering, 801 Ferst Drive, Georgia Institute of Technology, Atlanta, GA 30332-0405, United States","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering, 801 Ferst Drive, Georgia Institute of Technology, Atlanta, GA 30332-0405, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047148209","display_name":"Mahir Mohiuddin","orcid":"https://orcid.org/0000-0002-4916-5469","observed_orcids":["https://orcid.org/0000-0002-4916-5469"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahir Mohiuddin","raw_affiliation_strings":["Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078548351","display_name":"Shannon E. Anderson","orcid":"https://orcid.org/0000-0002-7438-0814","observed_orcids":["https://orcid.org/0000-0002-7438-0814"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon E. Anderson","raw_affiliation_strings":["Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011208920","display_name":"Andr\u00e9s J. Garc\u0131\u0301a","orcid":"https://orcid.org/0000-0001-6602-2518","observed_orcids":["https://orcid.org/0000-0001-6602-2518"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andr\u00e9s J. Garc\u00eda","raw_affiliation_strings":["Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering, 801 Ferst Drive, Georgia Institute of Technology, Atlanta, GA 30332-0405, United States","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering, 801 Ferst Drive, Georgia Institute of Technology, Atlanta, GA 30332-0405, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - George W. Woodruff School of Mechanical Engineering","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084217860","display_name":"Young Charles Jang","orcid":"https://orcid.org/0000-0002-9489-2104","observed_orcids":["https://orcid.org/0000-0002-9489-2104"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Young C. Jang","raw_affiliation_strings":["Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","Georgia Institute of Technology - School of Biological Sciences, Atlanta, GA, United States","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","Georgia Institute of Technology - School of Biological Sciences","Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience, Atlanta, GA 30332, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - School of Biological Sciences, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, United States","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]},{"raw_affiliation_string":"Georgia Institute of Technology - Parker H. Petit Institute for Bioengineering and Bioscience","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - School of Biological Sciences","institution_ids":["https://openalex.org/I130701444"]},{"raw_affiliation_string":"Georgia Institute of Technology - Wallace H. Coulter Department of Biomedical Engineering","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084217860"],"corresponding_institution_ids":["https://openalex.org/I130701444","https://openalex.org/I2802612298"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.4480000138282776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.4480000138282776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.24690000712871552,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.16760000586509705,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wnt7a","display_name":"Wnt7a","score":0.9959999918937683},{"id":"https://openalex.org/keywords/synthetic-hydrogels","display_name":"synthetic hydrogels","score":0.8930000066757202},{"id":"https://openalex.org/keywords/poly-ethylene-glycol-hydrogels","display_name":"poly(ethylene glycol) hydrogels","score":0.8880000114440918},{"id":"https://openalex.org/keywords/skeletal-muscle-regeneration","display_name":"skeletal muscle regeneration","score":0.9610000252723694},{"id":"https://openalex.org/keywords/muscle-stem-cells","display_name":"muscle stem cells","score":0.7850000262260437},{"id":"https://openalex.org/keywords/satellite-cells","display_name":"satellite cells","score":0.7570000290870667},{"id":"https://openalex.org/keywords/cell-engraftment","display_name":"cell engraftment","score":0.7390000224113464},{"id":"https://openalex.org/keywords/co-delivery","display_name":"co-delivery","score":0.7250000238418579},{"id":"https://openalex.org/keywords/controlled-protein-release","display_name":"controlled protein release","score":0.6639999747276306},{"id":"https://openalex.org/keywords/proteolysis","display_name":"proteolysis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cryoinjury","display_name":"cryoinjury","score":0.875},{"id":"https://openalex.org/keywords/tibialis-anterior","display_name":"tibialis anterior","score":0.8370000123977661},{"id":"https://openalex.org/keywords/pax7","display_name":"Pax7","score":0.6650000214576721},{"id":"https://openalex.org/keywords/muscle-trauma","display_name":"muscle trauma","score":0.5709999799728394},{"id":"https://openalex.org/keywords/muscular-dystrophy","display_name":"muscular dystrophy","score":0.7390000224113464},{"id":"https://openalex.org/keywords/regenerative-therapy","display_name":"regenerative therapy","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6973855495452881},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.6108779311180115},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.5143591165542603},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5010206699371338},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.439285010099411},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3605985641479492},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3161601424217224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.291667640209198},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.27580446004867554},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2509291172027588},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2307617962360382},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.3387689","doi":"https://doi.org/10.2139/ssrn.3387689","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3387689","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2139/ssrn.3387689","doi":"https://doi.org/10.2139/ssrn.3387689","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3387689","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2953328910","https://openalex.org/W2886088282","https://openalex.org/W4404046604","https://openalex.org/W4220771437","https://openalex.org/W7171970764","https://openalex.org/W3165937456","https://openalex.org/W2347206039","https://openalex.org/W2996711657","https://openalex.org/W3096231598","https://openalex.org/W7164506804"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2021-02-01T00:00:00"}
