{"id":"https://openalex.org/W3120925575","doi":"https://doi.org/10.1016/j.jmii.2020.12.009","title":"The Dynamic Change of Antibody Index Against COVID-19 Is a Powerful Diagnostic Tool for the Early Phase of the Infection and Salvage PCR Assay Errors","display_name":"The Dynamic Change of Antibody Index Against COVID-19 Is a Powerful Diagnostic Tool for the Early Phase of the Infection and Salvage PCR Assay Errors","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3120925575","doi":"https://doi.org/10.1016/j.jmii.2020.12.009","mag":"3120925575","pmid":"https://pubmed.ncbi.nlm.nih.gov/33593710","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7784537"},"language":"en","primary_location":{"id":"doi:10.1016/j.jmii.2020.12.009","doi":"https://doi.org/10.1016/j.jmii.2020.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmii.2020.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S7766676","display_name":"Journal of Microbiology Immunology and Infection","issn_l":"1684-1182","issn":["1684-1182","1995-9133"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microbiology, Immunology and Infection","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.jmii.2020.12.009","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034244372","display_name":"Masao Omata","orcid":"https://orcid.org/0000-0001-7977-1497","observed_orcids":["https://orcid.org/0000-0001-7977-1497"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Masao Omata","raw_affiliation_strings":["Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. Electronic address: m-omata0901@ych.pref.yamanashi.jp","Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. Electronic address: m-omata0901@ych.pref.yamanashi.jp","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I74801974"]},{"raw_affiliation_string":"Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]},{"raw_affiliation_string":"The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001342594","display_name":"Yosuke Hirotsu","orcid":"https://orcid.org/0000-0002-8002-834X","observed_orcids":["https://orcid.org/0000-0002-8002-834X"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yosuke Hirotsu","raw_affiliation_strings":["Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":"https://orcid.org/0000-0002-8002-834X","affiliations":[{"raw_affiliation_string":"Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroki Sugiura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki Sugiura","raw_affiliation_strings":["Division of Clinical Biochemistry and Immunology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Biochemistry and Immunology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053797248","display_name":"Makoto Maejima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Maejima","raw_affiliation_strings":["Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054179805","display_name":"Yuki Nagakubo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuki Nagakubo","raw_affiliation_strings":["Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]},{"raw_affiliation_string":"Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]},{"raw_affiliation_string":"Division of Microbiology in Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033420971","display_name":"Kenji Amemiya","orcid":"https://orcid.org/0000-0003-4223-0528","observed_orcids":["https://orcid.org/0000-0003-4223-0528"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Amemiya","raw_affiliation_strings":["Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Genetics and Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035389200","display_name":"Miyoko Hayakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Miyoko Hayakawa","raw_affiliation_strings":["Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014408489","display_name":"Toshiharu Tsutsui","orcid":"https://orcid.org/0000-0002-7007-6428","observed_orcids":["https://orcid.org/0000-0002-7007-6428"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiharu Tsutsui","raw_affiliation_strings":["Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016283693","display_name":"Yumiko Kakizaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yumiko Kakizaki","raw_affiliation_strings":["Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071650784","display_name":"Hitoshi Mochizuki","orcid":"https://orcid.org/0000-0002-1145-0969","observed_orcids":["https://orcid.org/0000-0002-1145-0969","https://orcid.org/0009-0009-4433-6001"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Mochizuki","raw_affiliation_strings":["Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Department of Gastroenterology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","Department of Gastroenterology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan; Department of Gastroenterology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]},{"raw_affiliation_string":"Central Clinical Laboratory, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]},{"raw_affiliation_string":"Department of Gastroenterology, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]},{"raw_affiliation_string":"Genome Analysis Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090461473","display_name":"Yoshihiro Miyashita","orcid":"https://orcid.org/0000-0002-3523-2368","observed_orcids":["https://orcid.org/0000-0002-3523-2368"]},"institutions":[{"id":"https://openalex.org/I4210166086","display_name":"Yamanashi Prefectural Central Hospital","ror":"https://ror.org/05r286q94","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210166086","https://openalex.org/I4405284837"]},{"id":"https://openalex.org/I4405284726","display_name":"Yamanashi Hospital","ror":"https://ror.org/044340c13","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210132540","https://openalex.org/I4405284726"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiro Miyashita","raw_affiliation_strings":["Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi, Japan","institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I4405284726"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5034244372"],"corresponding_institution_ids":["https://openalex.org/I4210166086","https://openalex.org/I74801974"],"apc_list":{"value":1350,"currency":"USD","value_usd":1350},"apc_paid":{"value":1350,"currency":"USD","value_usd":1350},"fwci":0.4383,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.77761201,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"54","issue":"5","first_page":"830","last_page":"838"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9639999866485596},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.8859999775886536},{"id":"https://openalex.org/keywords/antibody-index","display_name":"antibody index","score":0.5360000133514404},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.7649999856948853},{"id":"https://openalex.org/keywords/false-positive-results","display_name":"false positives","score":0.7099999785423279},{"id":"https://openalex.org/keywords/diamond-princess-cruise-ship","display_name":"Diamond Princess cruise ship","score":0.5910000205039978},{"id":"https://openalex.org/keywords/nurses","display_name":"nurses","score":0.32100000977516174},{"id":"https://openalex.org/keywords/diagnostic-test-validation","display_name":"diagnostic test validation","score":0.4869999885559082},{"id":"https://openalex.org/keywords/viral-load-dynamics","display_name":"viral load dynamics","score":0.42399999499320984},{"id":"https://openalex.org/keywords/point-of-care-testing","display_name":"point-of-care testing","score":0.6380000114440918},{"id":"https://openalex.org/keywords/sars-cov-2-rna-load","display_name":"SARS-CoV-2 RNA load","score":0.4359999895095825},{"id":"https://openalex.org/keywords/viral-shedding-duration","display_name":"viral shedding duration","score":0.3269999921321869},{"id":"https://openalex.org/keywords/sars-cov-2-rna-detection","display_name":"SARS-CoV-2 RNA detection","score":0.42800000309944153}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.611596941947937},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6049047708511353},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5304279327392578},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.523221492767334},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4860544502735138},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4209452271461487},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.42077183723449707},{"id":"https://openalex.org/C48023723","wikidata":"https://www.wikidata.org/wiki/Q856198","display_name":"Real-time polymerase chain reaction","level":3,"score":0.4170982837677002},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33018094301223755},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27750682830810547},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.10237190127372742},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07510656118392944},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.07483994960784912},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000086742","descriptor_name":"COVID-19 Testing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000087124","descriptor_name":"COVID-19 Serological Testing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000349","descriptor_name":"Africa","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003951","descriptor_name":"Diagnostic Errors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012767","descriptor_name":"Ships","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D042241","descriptor_name":"Early Diagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.jmii.2020.12.009","doi":"https://doi.org/10.1016/j.jmii.2020.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmii.2020.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S7766676","display_name":"Journal of Microbiology Immunology and Infection","issn_l":"1684-1182","issn":["1684-1182","1995-9133"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microbiology, Immunology and Infection","raw_type":"journal-article"},{"id":"doi:10.2139/ssrn.3627263","doi":"https://doi.org/10.2139/ssrn.3627263","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3627263","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7784537","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7784537/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7784537/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Microbiol Immunol Infect","raw_type":"Text"},{"id":"pmid:33593710","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33593710","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:c58044cae40143e98c5c7e8a3e240724","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/c58044cae40143e98c5c7e8a3e240724","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Microbiology, Immunology and Infection, Vol 54, Iss 5, Pp 830-838 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jmii.2020.12.009","doi":"https://doi.org/10.1016/j.jmii.2020.12.009","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jmii.2020.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S7766676","display_name":"Journal of Microbiology Immunology and Infection","issn_l":"1684-1182","issn":["1684-1182","1995-9133"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microbiology, Immunology and Infection","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1535794625","display_name":"Mechanisms of carcinogenesis in individuals harboring germline BRCA1/2 pathogenic variants","funder_award_id":"18K16292","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6827697900","display_name":"Association between tumor microbiota and genomic instability-mediated anti-tumor immunity in MSI-high gastric cancer","funder_award_id":"20H03668","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320309807","display_name":"Takeda Science Foundation","ror":"https://ror.org/02y123g31"},{"id":"https://openalex.org/F4320310760","display_name":"Uehara Memorial Foundation","ror":"https://ror.org/00gc20a07"},{"id":"https://openalex.org/F4320325293","display_name":"Yasuda Memorial Medical Foundation","ror":"https://ror.org/017cjzj15"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3120925575.pdf","grobid_xml":"https://content.openalex.org/works/W3120925575.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W2030041350","https://openalex.org/W2046702732","https://openalex.org/W2058218248","https://openalex.org/W2094768980","https://openalex.org/W2107574816","https://openalex.org/W2321075294","https://openalex.org/W3001118548","https://openalex.org/W3001897055","https://openalex.org/W3012184759","https://openalex.org/W3013435976","https://openalex.org/W3016641062","https://openalex.org/W3039061227","https://openalex.org/W3039985320","https://openalex.org/W3040552450","https://openalex.org/W3045391095","https://openalex.org/W3048917590","https://openalex.org/W3089010823","https://openalex.org/W3096559857","https://openalex.org/W3097210515","https://openalex.org/W3126981244","https://openalex.org/W6776170541","https://openalex.org/W6782391843"],"related_works":["https://openalex.org/W4318591515","https://openalex.org/W4308929519","https://openalex.org/W4312141080","https://openalex.org/W4252826893","https://openalex.org/W3133987520","https://openalex.org/W3020343087","https://openalex.org/W3113750943","https://openalex.org/W3031978825","https://openalex.org/W4280615094","https://openalex.org/W4206419151"],"abstract_inverted_index":{"Currently,":[0],"PCR":[1,23,89,181,189,223],"assay":[2,29],"is":[3],"a":[4,197,230],"golden":[5],"standard":[6],"for":[7],"diagnosis":[8],"of":[9,66,129,151,175,184,188,201,238],"Covid-19.":[10],"However,":[11],"it":[12],"needs":[13],"nasopharyngeal":[14],"swabs,":[15],"expensive":[16],"instruments":[17],"and":[18,35,82,97,119,131,137,217,241],"expertise.":[19],"It":[20],"even":[21,218],"causes":[22],"errors.":[24,224],"We":[25],"validated":[26],"the":[27,114,127,191,209,236,239],"antibody":[28,108,176,194],"(Roche)":[30],"in":[31,80,87,99,111,143,179,208,235],"36":[32,104],"followed":[33],"patients":[34,63],"1879":[36,41],"controls":[37],"(medical":[38],"staffs).":[39],"Of":[40,103],"medical":[42],"staffs,":[43],"only":[44],"two":[45,144],"(0.11%)":[46],"were":[47,64,91],"positive":[48,107,133,178,186],"by":[49],"Cut":[50],"off":[51],"Index":[52],"(COI;":[53],"1.0)":[54],"(mean":[55],"\u00b1":[56,59],"SD,":[57],"0.094":[58],"0.047).":[60],"Thirty":[61,139],"six":[62],"composed":[65],"three":[67],"groups;":[68],"Group":[69,76,83],"A,4":[70],"from":[71,113,117,121,124],"Diamond":[72],"Princess":[73],"cruise":[74],"ship,":[75,115],"B,":[77],"2":[78],"infected":[79,86],"Africa,":[81,118],"C,":[84],"30":[85],"Japan.":[88,122],"assays":[90],"conducted":[92],"at":[93,105,190],"outside":[94],"laboratories":[95],"before":[96],"repeated":[98],"house":[100,180],"after":[101],"hospitalized.":[102],"admission,":[106],"was":[109,141],"seen":[110],"4/4":[112],"0/2":[116],"5/30":[120],"Two":[123],"Africa":[125],"showed":[126,148],"increase":[128,150],"COI":[130,152,202],"became":[132],"on":[134],"days":[135,158],"8":[136],"13.":[138],"Japanese":[140],"divided":[142],"groups,":[145],"e.g.,":[146],"23":[147],"dynamic":[149,199],"up":[153],"to":[154,220],"84.4":[155],"within":[156],"3":[157],"while":[159],"active":[160],"virus":[161],"replication":[162],"present":[163],"(Group":[164,171],"C).":[165],"In":[166],"remaining":[167],"7":[168],"(7/30,":[169],"23%)":[170],"C'),":[172],"no":[173],"rise":[174],"nor":[177],"assays,":[182],"indicative":[183],"false":[185],"results":[187],"beginning.":[192],"This":[193,213],"testing":[195],"has":[196],"wide":[198],"ranges":[200],"and,":[203],"thus,":[204],"could":[205],"be":[206],"utilized":[207],"early":[210],"infection":[211],"phase.":[212],"may":[214],"also":[215],"compliment":[216],"help":[219],"avoid":[221],"possible":[222],"Therefore,":[225],"this":[226],"can":[227],"serve":[228],"as":[229],"powerful":[231],"diagnostic":[232],"tool,":[233],"needed":[234],"frontline":[237],"clinic":[240],"hospitals.":[242]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":9}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2021-01-18T00:00:00"}