{"id":"https://openalex.org/W3118920544","doi":"https://doi.org/10.29252/jmp.19.76.99","title":"Enhancement of Taxol production by applying amino acid complex along with chitosan in suspension culture of Taxus baccata L.","display_name":"Enhancement of Taxol production by applying amino acid complex along with chitosan in suspension culture of Taxus baccata L.","publication_year":2020,"publication_date":"2020-11-01","ids":{"openalex":"https://openalex.org/W3118920544","doi":"https://doi.org/10.29252/jmp.19.76.99","mag":"3118920544"},"language":"en","primary_location":{"id":"doi:10.29252/jmp.19.76.99","doi":"https://doi.org/10.29252/jmp.19.76.99","is_oa":true,"landing_page_url":"https://doi.org/10.29252/jmp.19.76.99","pdf_url":"http://jmp.ir/files/site1/user_files_8d9738/nassimzp-A-10-1189-1-46026ef.pdf","source":{"id":"https://openalex.org/S2764467031","display_name":"Journal of Medicinal Plants","issn_l":"1684-0240","issn":["1684-0240","2717-204X","2717-2058"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4376888875","host_organization_name":"Institute of Medicinal Plants, ACECR","host_organization_lineage":["https://openalex.org/P4376888875"],"host_organization_lineage_names":["Institute of Medicinal Plants, ACECR"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Plants","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://jmp.ir/files/site1/user_files_8d9738/nassimzp-A-10-1189-1-46026ef.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008824814","display_name":"Bahar Amirkavei Najafabadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55547365","display_name":"Payame Noor University","ror":"https://ror.org/031699d98","country_code":"IR","type":"education","lineage":["https://openalex.org/I55547365"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Bahar Amirkavei Najafabadi","raw_affiliation_strings":["Department of Agricultural Biotechnology, Payam Noor University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Biotechnology, Payam Noor University, Tehran, Iran","institution_ids":["https://openalex.org/I55547365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111046202","display_name":"Nasrin Qavami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802694670","display_name":"Academic Center for Education, Culture and Research","ror":"https://ror.org/0126z4b94","country_code":"IR","type":"nonprofit","lineage":["https://openalex.org/I2802694670"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Nasrin Qavami","raw_affiliation_strings":["Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran","institution_ids":["https://openalex.org/I2802694670"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mohammad Ali Ebrahimi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55547365","display_name":"Payame Noor University","ror":"https://ror.org/031699d98","country_code":"IR","type":"education","lineage":["https://openalex.org/I55547365"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammad Ali Ebrahimi","raw_affiliation_strings":["Department of Agricultural Biotechnology, Payam Noor University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Biotechnology, Payam Noor University, Tehran, Iran","institution_ids":["https://openalex.org/I55547365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083827881","display_name":"Peyman Ebrahimi","orcid":"https://orcid.org/0000-0003-4372-9339","observed_orcids":["https://orcid.org/0000-0003-4372-9339"]},"institutions":[{"id":"https://openalex.org/I110525433","display_name":"Islamic Azad University, Tehran","ror":"https://ror.org/01kzn7k21","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433"]},{"id":"https://openalex.org/I155419210","display_name":"Islamic Azad University, Science and Research Branch","ror":"https://ror.org/03187yj51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Peyman Ebrahimi","raw_affiliation_strings":["Agricultural Sciences and Food Industries Faculty, Science and Research Branch, Islamic Azad University, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Sciences and Food Industries Faculty, Science and Research Branch, Islamic Azad University, Tehran, Iran","institution_ids":["https://openalex.org/I110525433","https://openalex.org/I155419210"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067834152","display_name":"Nasim Zarinpanjeh","orcid":"https://orcid.org/0000-0003-3656-8135","observed_orcids":["https://orcid.org/0000-0003-3656-8135"]},"institutions":[{"id":"https://openalex.org/I2802694670","display_name":"Academic Center for Education, Culture and Research","ror":"https://ror.org/0126z4b94","country_code":"IR","type":"nonprofit","lineage":["https://openalex.org/I2802694670"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Nasim Zarinpanjeh","raw_affiliation_strings":["Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran","institution_ids":["https://openalex.org/I2802694670"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5067834152"],"corresponding_institution_ids":["https://openalex.org/I2802694670"],"apc_list":null,"apc_paid":null,"fwci":0.7904,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.69995204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"19","issue":"76","first_page":"99","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paclitaxel","display_name":"paclitaxel","score":0.8790000081062317},{"id":"https://openalex.org/keywords/taxus-baccata","display_name":"Taxus baccata","score":0.925000011920929},{"id":"https://openalex.org/keywords/cell-suspension-culture","display_name":"cell suspension culture","score":0.7919999957084656},{"id":"https://openalex.org/keywords/chitosan","display_name":"chitosan","score":0.9079999923706055},{"id":"https://openalex.org/keywords/amino-acid-complexes","display_name":"amino acid complexes","score":0.9700000286102295},{"id":"https://openalex.org/keywords/elicitors","display_name":"elicitors","score":0.7409999966621399},{"id":"https://openalex.org/keywords/callus-induction","display_name":"callus induction","score":0.8550000190734863},{"id":"https://openalex.org/keywords/secondary-metabolite-production","display_name":"secondary metabolite production","score":0.7360000014305115},{"id":"https://openalex.org/keywords/plant-tissue-culture","display_name":"plant tissue culture","score":0.49399998784065247},{"id":"https://openalex.org/keywords/2-4-d","display_name":"2,4-D","score":0.8809999823570251},{"id":"https://openalex.org/keywords/naa","display_name":"NAA","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C2778894183","wikidata":"https://www.wikidata.org/wiki/Q27355","display_name":"Taxus","level":2,"score":0.9743213653564453},{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.696029782295227},{"id":"https://openalex.org/C2993787908","wikidata":"https://www.wikidata.org/wiki/Q189111","display_name":"Suspension culture","level":3,"score":0.6480257511138916},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.481962651014328},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.4711301028728485},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.40373653173446655},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.31896889209747314},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.293366938829422},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.287932813167572},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.21400678157806396},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14964240789413452},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.29252/jmp.19.76.99","doi":"https://doi.org/10.29252/jmp.19.76.99","is_oa":true,"landing_page_url":"https://doi.org/10.29252/jmp.19.76.99","pdf_url":"http://jmp.ir/files/site1/user_files_8d9738/nassimzp-A-10-1189-1-46026ef.pdf","source":{"id":"https://openalex.org/S2764467031","display_name":"Journal of Medicinal Plants","issn_l":"1684-0240","issn":["1684-0240","2717-204X","2717-2058"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4376888875","host_organization_name":"Institute of Medicinal Plants, ACECR","host_organization_lineage":["https://openalex.org/P4376888875"],"host_organization_lineage_names":["Institute of Medicinal Plants, ACECR"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Plants","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:36d67618590e45d1815514c906bad432","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/36d67618590e45d1815514c906bad432","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Medicinal Plants, Vol 19, Iss 76, Pp 99-109 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.29252/jmp.19.76.99","doi":"https://doi.org/10.29252/jmp.19.76.99","is_oa":true,"landing_page_url":"https://doi.org/10.29252/jmp.19.76.99","pdf_url":"http://jmp.ir/files/site1/user_files_8d9738/nassimzp-A-10-1189-1-46026ef.pdf","source":{"id":"https://openalex.org/S2764467031","display_name":"Journal of Medicinal Plants","issn_l":"1684-0240","issn":["1684-0240","2717-204X","2717-2058"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4376888875","host_organization_name":"Institute of Medicinal Plants, ACECR","host_organization_lineage":["https://openalex.org/P4376888875"],"host_organization_lineage_names":["Institute of Medicinal Plants, ACECR"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medicinal Plants","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323057","display_name":"Academic Center for Education, Culture and Research","ror":"https://ror.org/0126z4b94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3118920544.pdf","grobid_xml":"https://content.openalex.org/works/W3118920544.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W4596803","https://openalex.org/W157373330","https://openalex.org/W1252602816","https://openalex.org/W1508914654","https://openalex.org/W1886677716","https://openalex.org/W1965708712","https://openalex.org/W1974778283","https://openalex.org/W1978072140","https://openalex.org/W1983769329","https://openalex.org/W1992734024","https://openalex.org/W2015065509","https://openalex.org/W2015429280","https://openalex.org/W2024556021","https://openalex.org/W2036886024","https://openalex.org/W2038271952","https://openalex.org/W2065874534","https://openalex.org/W2069688817","https://openalex.org/W2073706033","https://openalex.org/W2081217370","https://openalex.org/W2082462476","https://openalex.org/W2084464626","https://openalex.org/W2086514756","https://openalex.org/W2087721918","https://openalex.org/W2092535428","https://openalex.org/W2098258528","https://openalex.org/W2102432232","https://openalex.org/W2113689755","https://openalex.org/W2139084464","https://openalex.org/W2182417412","https://openalex.org/W2256982982","https://openalex.org/W2410802063","https://openalex.org/W2467072783","https://openalex.org/W2603652448","https://openalex.org/W2617649247","https://openalex.org/W2793428822","https://openalex.org/W2890723015","https://openalex.org/W2901642830","https://openalex.org/W2902218278","https://openalex.org/W2916658539"],"related_works":["https://openalex.org/W2069688817","https://openalex.org/W1508914654","https://openalex.org/W2377949354","https://openalex.org/W2569780558","https://openalex.org/W2092535428","https://openalex.org/W2349171645","https://openalex.org/W1978970998","https://openalex.org/W2377456327","https://openalex.org/W2038271952","https://openalex.org/W1991230548"],"abstract_inverted_index":{"Background:":[0],"Taxol":[1,39,79,176,204],"(Paclitaxel)":[2],"has":[3],"been":[4],"highly":[5],"recommended":[6],"to":[7,26,42,110,148],"control":[8],"and":[9,20,29,116,142,162],"treat":[10],"a":[11],"wide":[12],"range":[13],"of":[14,23,31,61,74,85,153,167,175,210],"cancers.Taxus":[15],"baccata":[16,76,87],"L.":[17],"is":[18,41,200],"primary":[19],"natural":[21],"origin":[22],"Taxol.Objective:":[24],"Due":[25],"severe":[27],"restriction":[28],"prohibition":[30],"cutting":[32],"T.":[33,75,86,211],"baccata,":[34],"the":[35,52,56,59,97,100,103,150,172],"alternative":[36],"way":[37],"for":[38,55,77,202],"production":[40,80,174,205],"apply":[43],"in":[44,70,92,122,128,179,206],"vitro":[45],"culture":[46,73,209],"method":[47],"which":[48],"was":[49,81],"implemented":[50],"at":[51,139,144],"current":[53],"study.Here,":[54],"first":[57],"time,":[58],"effect":[60],"amino":[62,117,185,193],"acid":[63,118,194],"complex":[64,119,187,195],"as":[65,88,196],"elicitor":[66,197],"along":[67],"with":[68,124,137,188,198],"chitosan":[69,115,199],"cell":[71,111,207],"suspension":[72,112,208],"enhancing":[78,203],"studied.Methods:":[82],"Young":[83],"leaves":[84],"explants":[89],"were":[90,108,130],"cultured":[91],"different":[93],"callus":[94,105,154],"induction":[95,106,155],"treatments.At":[96],"next":[98],"step,":[99],"calli":[101],"from":[102],"best":[104,151],"treatment":[107,152],"transferred":[109],"cultures":[113],"containing":[114],"alone":[120],"or":[121],"combination":[123],"each":[125],"other.Taxol":[126],"content":[127],"treatments":[129],"measured":[131],"by":[132],"HPLC.Results:":[133],"MS":[134,180],"medium":[135,181],"supplemented":[136],"2,4-D":[138],"2":[140,183],"mg/L":[141,146,190],"NAA":[143],"1":[145],"proved":[147],"be":[149],"(100":[156],"%),":[157],"fresh":[158],"weight":[159,164],"(495":[160],"mg)":[161,166],"dry":[163],"(272":[165],"calli.Also,":[168],"HPLC":[169],"analysis":[170],"confirmed":[171],"maximum":[173],"(1.96":[177],"mg/g)":[178],"having":[182],"ml/L":[184],"acids":[186],"10":[189],"chitosan.Conclusion:":[191],"Applying":[192],"suggested":[201],"baccata.":[212]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-01-18T00:00:00"}