{"id":"https://openalex.org/W3118564209","doi":"https://doi.org/10.1007/s40556-020-00281-4","title":"Retrograde Flow in the Aortic Isthmus: Trigger to Deliver Growth Restricted Fetuses Between 30 and 34 Weeks of Gestation?","display_name":"Retrograde Flow in the Aortic Isthmus: Trigger to Deliver Growth Restricted Fetuses Between 30 and 34 Weeks of Gestation?","publication_year":2020,"publication_date":"2020-12-01","ids":{"openalex":"https://openalex.org/W3118564209","doi":"https://doi.org/10.1007/s40556-020-00281-4","mag":"3118564209"},"language":"en","primary_location":{"id":"doi:10.1007/s40556-020-00281-4","doi":"https://doi.org/10.1007/s40556-020-00281-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40556-020-00281-4","pdf_url":null,"source":{"id":"https://openalex.org/S2764811767","display_name":"Journal of Fetal Medicine","issn_l":"2348-1153","issn":["2348-1153","2348-8859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fetal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1007/s40556-020-00281-4","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048205984","display_name":"Shalaka Arun Bansode","orcid":"https://orcid.org/0000-0002-2778-930X","observed_orcids":["https://orcid.org/0000-0002-2778-930X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Shalaka Arun Bansode","raw_affiliation_strings":["Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035806211","display_name":"Bijoy Balakrishnan","orcid":"https://orcid.org/0000-0002-5200-7875","observed_orcids":["https://orcid.org/0000-0002-5200-7875"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bijoy Balakrishnan","raw_affiliation_strings":["Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102841224","display_name":"Meenu Batra","orcid":"https://orcid.org/0000-0002-6531-8218","observed_orcids":["https://orcid.org/0000-0002-6531-8218"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meenu Batra","raw_affiliation_strings":["Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077222464","display_name":"P. S. Sreeja","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. S. Sreeja","raw_affiliation_strings":["Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086105550","display_name":"N. Patil Swapneel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Patil Swapneel","raw_affiliation_strings":["Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, 679576, Edappal, Malappuram, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"Department of Fetomaternal Medicine, Centre for Infertility Management and Assisted Reproduction (CIMAR), Edappal Hospitals Pvt. Ltd, Edappal, Malappuram, Kerala, 679576, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026255263","display_name":"K. K. Gopinathan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. K. Gopinathan","raw_affiliation_strings":["Obstetrics and Gynecology, CIMAR, Edappal Hospitals Pvt. Ltd., Edappal, Malappuram, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Obstetrics and Gynecology, CIMAR, Edappal Hospitals Pvt. Ltd., Edappal, Malappuram, Kerala, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5035806211","https://openalex.org/A5048205984"],"corresponding_institution_ids":[],"apc_list":{"value":3260,"currency":"USD","value_usd":3260},"apc_paid":{"value":3260,"currency":"USD","value_usd":3260},"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.26036517,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"07","issue":"04","first_page":"267","last_page":"274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12272","display_name":"Cardiovascular Conditions and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.8820000290870667},{"id":"https://openalex.org/keywords/aortic-isthmus","display_name":"aortic isthmus","score":0.925000011920929},{"id":"https://openalex.org/keywords/retrograde-flow","display_name":"retrograde flow","score":0.8579999804496765},{"id":"https://openalex.org/keywords/antegrade-flow","display_name":"antegrade flow","score":0.7799999713897705},{"id":"https://openalex.org/keywords/absent-end-diastolic-flow","display_name":"absent end-diastolic flow","score":0.8489999771118164},{"id":"https://openalex.org/keywords/umbilical-artery-doppler","display_name":"umbilical artery Doppler","score":0.972000002861023},{"id":"https://openalex.org/keywords/ductus-venosus-flow","display_name":"ductus venosus flow","score":0.8539999723434448},{"id":"https://openalex.org/keywords/perinatal-outcomes","display_name":"perinatal outcomes","score":0.8600000143051147},{"id":"https://openalex.org/keywords/perinatal-mortality","display_name":"perinatal mortality","score":0.8199999928474426},{"id":"https://openalex.org/keywords/intrauterine-fetal-death","display_name":"intrauterine fetal death","score":0.8009999990463257},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.8109999895095825},{"id":"https://openalex.org/keywords/early-delivery","display_name":"early delivery","score":0.36899998784065247}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9193011522293091},{"id":"https://openalex.org/C2778152043","wikidata":"https://www.wikidata.org/wiki/Q942823","display_name":"Ductus venosus","level":4,"score":0.8356826305389404},{"id":"https://openalex.org/C2778964498","wikidata":"https://www.wikidata.org/wiki/Q1724233","display_name":"Umbilical artery","level":4,"score":0.6560212969779968},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.5183395147323608},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4989502429962158},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.483280211687088},{"id":"https://openalex.org/C2778780700","wikidata":"https://www.wikidata.org/wiki/Q1671598","display_name":"Intrauterine growth restriction","level":4,"score":0.45244309306144714},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4303719997406006},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3605119287967682},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2932431697845459},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s40556-020-00281-4","doi":"https://doi.org/10.1007/s40556-020-00281-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40556-020-00281-4","pdf_url":null,"source":{"id":"https://openalex.org/S2764811767","display_name":"Journal of Fetal Medicine","issn_l":"2348-1153","issn":["2348-1153","2348-8859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fetal Medicine","raw_type":"journal-article"},{"id":"doi:10.22541/au.158316313.34576871","doi":"https://doi.org/10.22541/au.158316313.34576871","is_oa":true,"landing_page_url":"https://doi.org/10.22541/au.158316313.34576871","pdf_url":"https://www.authorea.com/doi/pdf/10.22541/au.158316313.34576871","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1007/s40556-020-00281-4","doi":"https://doi.org/10.1007/s40556-020-00281-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40556-020-00281-4","pdf_url":null,"source":{"id":"https://openalex.org/S2764811767","display_name":"Journal of Fetal Medicine","issn_l":"2348-1153","issn":["2348-1153","2348-8859"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fetal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","score":0.8100000023841858,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W91430094","https://openalex.org/W1971538928","https://openalex.org/W1976985815","https://openalex.org/W1977115781","https://openalex.org/W1979282535","https://openalex.org/W1988337952","https://openalex.org/W1992880777","https://openalex.org/W2001338687","https://openalex.org/W2021209424","https://openalex.org/W2038205890","https://openalex.org/W2039503336","https://openalex.org/W2089481117","https://openalex.org/W2091709783","https://openalex.org/W2127873924","https://openalex.org/W2130529689","https://openalex.org/W2519262228"],"related_works":["https://openalex.org/W2058307634","https://openalex.org/W1977983527","https://openalex.org/W1967956321","https://openalex.org/W2372471236","https://openalex.org/W2022564935","https://openalex.org/W2167012565","https://openalex.org/W1997448451","https://openalex.org/W2035632520","https://openalex.org/W2083109909","https://openalex.org/W2523895661"],"abstract_inverted_index":{"Abstract":[0],"Objective":[1],"To":[2],"evaluate":[3],"the":[4,49,81,120,130,148,154,177,221,227,233,252],"association":[5],"of":[6,48,96,198],"aortic":[7,50],"isthmus":[8],"(AoI)":[9],"circulation":[10],"assessed":[11],"by":[12],"doppler":[13],"imaging":[14],"in":[15,80,119,129,147,153,166,176,216,220,226,232,251],"growth":[16,33],"restricted":[17],"fetuses":[18,217,245],"with":[19,103,135,168,181,218,249],"perinatal":[20,67,98,110,125,183],"outcome.":[21],"Design":[22],"Prospective":[23],"longitudinal":[24,255],"observational":[25],"study.":[26],"Setting":[27],"Tertiary":[28],"referral":[29],"center.":[30],"Population":[31],"Fetal":[32],"restriction":[34],"(FGR)":[35],"(n":[36,71,77],"=":[37,72,78],"38)":[38],"between":[39,66],"24":[40],"and":[41,58,69,74,83,106,114,150,156,195,223],"36":[42],"weeks\u2019":[43],"gestation.":[44],"Methods":[45],"Doppler":[46,85],"examination":[47],"isthmus,":[51],"umbilical":[52],"artery":[53],"(UA),":[54],"middle":[55],"cerebral":[56],"artery,":[57],"ductus":[59],"venosus":[60],"(DV)":[61],"was":[62,87,117,127],"performed.":[63],"The":[64],"relationship":[65],"outcomes":[68],"antegrade":[70,131],"25)":[73],"retrograde":[75,121,151,224,230],"flow":[76,139,145,152,159,175,208,225,231],"13)":[79],"AoI":[82,91,132,155,178,234],"other":[84],"parameters":[86],"analysed.":[88],"Results":[89],"Retrograde":[90,173],"group":[92,122],"had":[93,160],"higher":[94,118],"rates":[95],"adverse":[97,182,211],"outcome":[99,212],"(92.3%":[100],"vs.":[101],"72%)":[102],"63.1%":[104],"sensitivity":[105],"87.5%":[107],"specificity.":[108],"Overall":[109],"mortality":[111,126,163],"(intrauterine":[112],"death":[113],"neonatal":[115,189],"death)":[116],"(23%).":[123],"No":[124],"seen":[128],"group.":[133],"Cases":[134],"absent":[136],"end":[137,143],"diastolic":[138,144],"(AEDF)":[140],"or":[141],"reverse":[142],"(REDF)":[146],"UA":[149,222],"normal":[157],"DV":[158,170,207],"40%":[161],"prenatal":[162],"as":[164,238],"25%":[165],"those":[167],"abnormal":[169],"Doppler.":[171],"Conclusion":[172],"blood":[174],"is":[179,209],"associated":[180],"outcome,":[184],"particularly":[185],"intrauterine":[186],"fetal":[187],"demise,":[188],"death,":[190],"Respiratory":[191],"Distress":[192],"Syndrome":[193],"(RDS)":[194],"increased":[196],"duration":[197],"Neonatal":[199],"Intensive":[200],"Care":[201],"Unit":[202],"(NICU)":[203],"stay.":[204],"Even":[205],"if":[206],"normal,":[210],"might":[213,235],"be":[214,236],"suspected":[215],"AEDF/REDF":[219],"AoI.":[228],"Consequently,":[229],"considered":[237],"an":[239],"additional":[240],"trigger":[241],"for":[242],"delivering":[243],"FGR":[244],"at":[246],"30\u201334":[247],"weeks":[248],"AREDF":[250],"UA.":[253],"Larger":[254],"studies":[256],"are,":[257],"however,":[258],"required":[259],"to":[260],"vaidate":[261],"this.":[262]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}
