{"id":"https://openalex.org/W3118468002","doi":"https://doi.org/10.1167/tvst.10.1.12","title":"Predicting Age From Optical Coherence Tomography Scans With Deep Learning","display_name":"Predicting Age From Optical Coherence Tomography Scans With Deep Learning","publication_year":2021,"publication_date":"2021-01-07","ids":{"openalex":"https://openalex.org/W3118468002","doi":"https://doi.org/10.1167/tvst.10.1.12","mag":"3118468002","pmid":"https://pubmed.ncbi.nlm.nih.gov/33510951","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7804495"},"language":"en","primary_location":{"id":"doi:10.1167/tvst.10.1.12","doi":"https://doi.org/10.1167/tvst.10.1.12","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.10.1.12","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1167/tvst.10.1.12","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089526414","display_name":"Leonardo Shigueoka","orcid":"https://orcid.org/0000-0001-7077-8086","observed_orcids":["https://orcid.org/0000-0001-7077-8086"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Leonardo S. Shigueoka","raw_affiliation_strings":["Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil","Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil","institution_ids":["https://openalex.org/I181391015"]},{"raw_affiliation_string":"Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050146591","display_name":"Eduardo B. Mariottoni","orcid":"https://orcid.org/0000-0001-8808-1789","observed_orcids":["https://orcid.org/0000-0001-8808-1789"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eduardo B. Mariottoni","raw_affiliation_strings":["Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055312303","display_name":"Atalie C. Thompson","orcid":"https://orcid.org/0000-0002-2817-6417","observed_orcids":["https://orcid.org/0000-0002-2817-6417"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Atalie C. Thompson","raw_affiliation_strings":["Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013584197","display_name":"Alessandro A. Jammal","orcid":"https://orcid.org/0000-0001-5341-8353","observed_orcids":["https://orcid.org/0000-0001-5341-8353"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Alessandro A. Jammal","raw_affiliation_strings":["Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil","Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil","institution_ids":["https://openalex.org/I181391015"]},{"raw_affiliation_string":"Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051565290","display_name":"Vital Paulino Costa","orcid":"https://orcid.org/0000-0001-6147-4611","observed_orcids":["https://orcid.org/0000-0001-6147-4611"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vital P. Costa","raw_affiliation_strings":["Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaucoma Service, Department of Ophthalmology, University of Campinas, Campinas, Sa\u0303o Paulo, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075198015","display_name":"Felipe Andrade Medeiros","orcid":"https://orcid.org/0000-0003-3924-2720","observed_orcids":["https://orcid.org/0000-0003-3924-2720"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Felipe A. Medeiros","raw_affiliation_strings":["Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vision, Imaging and Performance Laboratory (VIP), Duke Eye Center and Department of Ophthalmology, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5075198015"],"corresponding_institution_ids":["https://openalex.org/I170897317"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":2.0702,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.86615857,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"10","issue":"1","first_page":"12","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/age-prediction","display_name":"age prediction","score":0.8899999856948853},{"id":"https://openalex.org/keywords/spectral-domain-optical-coherence-tomography","display_name":"spectral-domain optical coherence tomography","score":0.9610000252723694},{"id":"https://openalex.org/keywords/convolutional-neural-networks","display_name":"convolutional neural networks","score":0.8939999938011169},{"id":"https://openalex.org/keywords/retinal-aging","display_name":"retinal aging","score":0.7450000047683716},{"id":"https://openalex.org/keywords/choroid","display_name":"choroid","score":0.9110000133514404},{"id":"https://openalex.org/keywords/vitreous-body","display_name":"vitreous humor","score":0.9879999756813049},{"id":"https://openalex.org/keywords/retinal-nerve-fiber-layer","display_name":"retinal nerve fiber layer","score":0.9929999709129333},{"id":"https://openalex.org/keywords/class-activation-maps","display_name":"class activation maps","score":0.9279999732971191}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.7875524759292603},{"id":"https://openalex.org/C2780592520","wikidata":"https://www.wikidata.org/wiki/Q4423908","display_name":"Nerve fiber layer","level":3,"score":0.5869839191436768},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.578611433506012},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5652549266815186},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5327150225639343},{"id":"https://openalex.org/C2776694393","wikidata":"https://www.wikidata.org/wiki/Q271762","display_name":"Choroid","level":3,"score":0.47776472568511963},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.46429404616355896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45394518971443176},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.43452128767967224},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35232627391815186},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2640607953071594},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.19851094484329224},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1685723066329956},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1361106038093567},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13373014330863953},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10043039917945862},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1167/tvst.10.1.12","doi":"https://doi.org/10.1167/tvst.10.1.12","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.10.1.12","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:6745571","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7804495","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7804495","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7804495","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transl Vis Sci Technol","raw_type":"Text"},{"id":"pmid:33510951","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33510951","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational vision science & technology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1167/tvst.10.1.12","doi":"https://doi.org/10.1167/tvst.10.1.12","is_oa":true,"landing_page_url":"https://doi.org/10.1167/tvst.10.1.12","pdf_url":null,"source":{"id":"https://openalex.org/S2764591444","display_name":"Translational Vision Science & Technology","issn_l":"2164-2591","issn":["2164-2591"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315919","host_organization_name":"Association for Research in Vision and Ophthalmology","host_organization_lineage":["https://openalex.org/P4310315919"],"host_organization_lineage_names":["Association for Research in Vision and Ophthalmology"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Translational Vision Science &amp; Technology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1889567339","display_name":"Objective Quantification of Neural Damage for Screening, Diagnosis and Monitoring of Glaucoma with Fundus Photographs","funder_award_id":"R21EY031898","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8187636677","display_name":"The BCI (Brain Computer Interface) Glaucoma Study: Objective Home-Based Detection of Progressive Visual Function Loss in Glaucoma","funder_award_id":"R01EY029885","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W6335717","https://openalex.org/W172046951","https://openalex.org/W1505132263","https://openalex.org/W1594870591","https://openalex.org/W1968798833","https://openalex.org/W1977286054","https://openalex.org/W1984748796","https://openalex.org/W1989482166","https://openalex.org/W1996144177","https://openalex.org/W2003052705","https://openalex.org/W2006255376","https://openalex.org/W2021933371","https://openalex.org/W2026386627","https://openalex.org/W2027185272","https://openalex.org/W2029430539","https://openalex.org/W2034581610","https://openalex.org/W2043163806","https://openalex.org/W2048258786","https://openalex.org/W2049416620","https://openalex.org/W2052168562","https://openalex.org/W2058399269","https://openalex.org/W2064791649","https://openalex.org/W2104704101","https://openalex.org/W2112689098","https://openalex.org/W2117539524","https://openalex.org/W2141771435","https://openalex.org/W2149860264","https://openalex.org/W2194775991","https://openalex.org/W2195102649","https://openalex.org/W2319016705","https://openalex.org/W2418802570","https://openalex.org/W2533800772","https://openalex.org/W2544860310","https://openalex.org/W2557738935","https://openalex.org/W2734300443","https://openalex.org/W2752747624","https://openalex.org/W2765116315","https://openalex.org/W2772246530","https://openalex.org/W2919115771","https://openalex.org/W2962858109","https://openalex.org/W2976808722","https://openalex.org/W2987092895","https://openalex.org/W2999851965","https://openalex.org/W3003595546","https://openalex.org/W3005665173","https://openalex.org/W3006242086","https://openalex.org/W3143888242"],"related_works":["https://openalex.org/W3164730021","https://openalex.org/W4214859881","https://openalex.org/W4396622532","https://openalex.org/W3204950947","https://openalex.org/W4415734658","https://openalex.org/W2768217608","https://openalex.org/W3084069549","https://openalex.org/W4226052069","https://openalex.org/W4403436250","https://openalex.org/W4205094332"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"assess":[2],"whether":[3],"age":[4,44,88,113,123,189,220],"can":[5],"be":[6],"predicted":[7,85],"from":[8,101,221],"deep":[9],"learning":[10,34],"analysis":[11],"of":[12,25,98,104,112,145,156,169,178],"peripapillary":[13,49,223],"spectral-domain":[14],"optical":[15],"coherence":[16],"tomography":[17],"(SD-OCT)":[18],"B-scans":[19],"and":[20,74,82,86,142,193],"to":[21,41,91,164,217,231,238],"determine":[22],"the":[23,30,57,76,115,140,151,172,179,181,184,191,205,243],"importance":[24],"specific":[26,64,176],"retinal":[27,200],"areas":[28],"on":[29],"predictions.":[31],"Methods:":[32],"Deep":[33],"(DL)":[35],"convolutional":[36],"neural":[37],"networks":[38],"were":[39,54,89,108,118,190],"developed":[40],"predict":[42,219],"chronological":[43,122,188],"in":[45,242],"healthy":[46,106],"subjects":[47,107],"using":[48,56,63,114],"SD-OCT":[50,224,232],"B-scan":[51,117],"images.":[52],"Models":[53],"built":[55],"whole":[58,116,222],"B-scan,":[59,180],"as":[60,62],"well":[61],"regions":[65],"through":[66],"image":[67],"ablation.":[68],"Cross-validation":[69],"was":[70,215],"used":[71,90],"for":[72],"training":[73],"testing":[75],"model.":[77],"Mean":[78],"absolute":[79],"error":[80],"(MAE)":[81],"correlations":[83,186],"between":[84,139],"observed":[87],"evaluate":[92],"model":[93,135],"performance.":[94],"Results:":[95],"A":[96,212],"total":[97],"7271":[99],"images":[100],"542":[102],"eyes":[103],"278":[105],"included.":[109],"DL":[110,213,228],"predictions":[111],"strongly":[119],"correlated":[120],"with":[121,147,183,187],"(MAE":[124],"=":[125,129,197,209],"5.82":[126],"years;":[127],"r":[128,196],"0.860,":[130],"P":[131],"<":[132],"0.001).":[133],"The":[134],"also":[136],"accurately":[137,218],"discriminated":[138],"lowest":[141,206],"highest":[143],"tertiles":[144],"age,":[146],"an":[148],"area":[149],"under":[150],"receiver":[152],"operating":[153],"characteristic":[154],"curve":[155],"0.962.":[157],"In":[158],"general,":[159],"class":[160],"activation":[161,170],"maps":[162],"tended":[163],"show":[165],"a":[166],"diffuse":[167],"pattern":[168],"throughout":[171],"scan":[173],"image.":[174],"For":[175],"structures":[177],"layers":[182,241],"strongest":[185],"choroid":[192],"vitreous":[194],"(both":[195],"0.736),":[198],"whereas":[199],"nerve":[201],"fiber":[202],"layer":[203],"had":[204],"correlation":[207],"(r":[208],"0.492).":[210],"Conclusions:":[211],"algorithm":[214],"able":[216],"B-scans.":[225],"Translational":[226],"Relevance:":[227],"models":[229],"applied":[230],"scans":[233],"suggest":[234],"that":[235],"aging":[236],"appears":[237],"affect":[239],"several":[240],"posterior":[244],"eye":[245],"segment.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-01-18T00:00:00"}
