{"id":"https://openalex.org/W3116484232","doi":null,"title":"Combination of GSK3 and HDAC inhibitors increases gene expression efficiency to the hypoxia/neuron- specific system : an optimal experimental scheme in treating spinal cord injury","display_name":"Combination of GSK3 and HDAC inhibitors increases gene expression efficiency to the hypoxia/neuron- specific system : an optimal experimental scheme in treating spinal cord injury","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3116484232","mag":"3116484232"},"language":"en","primary_location":{"id":"mag:3116484232","doi":null,"is_oa":false,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/181182/1/TA02491.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050291067","display_name":"Zhimin Pan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Zhimin Pan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050291067"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.7056000232696533,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.7056000232696533,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.22139999270439148,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.023099999874830246,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gsk-3-inhibitors","display_name":"GSK-3 inhibitors","score":0.8679999709129333},{"id":"https://openalex.org/keywords/histone-deacetylase-inhibitors","display_name":"histone deacetylase inhibitors","score":0.9300000071525574},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7210000157356262},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.6909999847412109},{"id":"https://openalex.org/keywords/neuron-specific-gene-expression","display_name":"neuron-specific gene expression","score":0.7799999713897705},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9779999852180481},{"id":"https://openalex.org/keywords/gene-expression-efficiency","display_name":"gene expression efficiency","score":0.4880000054836273}],"concepts":[{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6433702111244202},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.5960844159126282},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.5201171636581421},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.516089141368866},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41871803998947144},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4144405424594879},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.356644868850708},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3043396472930908},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21697211265563965},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3116484232","doi":null,"is_oa":false,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/181182/1/TA02491.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1575406884","https://openalex.org/W1737750271","https://openalex.org/W1839559485","https://openalex.org/W1932303130","https://openalex.org/W1966417063","https://openalex.org/W1966453613","https://openalex.org/W1974432822","https://openalex.org/W1988875977","https://openalex.org/W2000829157","https://openalex.org/W2011933865","https://openalex.org/W2033500695","https://openalex.org/W2034753731","https://openalex.org/W2042899565","https://openalex.org/W2047361593","https://openalex.org/W2058413487","https://openalex.org/W2063243573","https://openalex.org/W2066845984","https://openalex.org/W2069165638","https://openalex.org/W2072327861","https://openalex.org/W2074131381","https://openalex.org/W2075136524","https://openalex.org/W2077781198","https://openalex.org/W2089426706","https://openalex.org/W2095238537","https://openalex.org/W2121396070","https://openalex.org/W2168250872","https://openalex.org/W2212633910","https://openalex.org/W2403316728","https://openalex.org/W2568797354","https://openalex.org/W2588375231","https://openalex.org/W2589409600","https://openalex.org/W2604262408","https://openalex.org/W2729217285","https://openalex.org/W2733631963","https://openalex.org/W2746573931","https://openalex.org/W2768163882","https://openalex.org/W2768445585","https://openalex.org/W2811347626","https://openalex.org/W2868920275","https://openalex.org/W2895496651","https://openalex.org/W2897560003","https://openalex.org/W2952483939","https://openalex.org/W2970690889"],"related_works":["https://openalex.org/W3047393323","https://openalex.org/W2584596246","https://openalex.org/W7038582772","https://openalex.org/W2965201998","https://openalex.org/W2751437455","https://openalex.org/W3211640857","https://openalex.org/W2587731914","https://openalex.org/W4387306339","https://openalex.org/W4410315591","https://openalex.org/W873321977"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2021-01-05T00:00:00"}