{"id":"https://openalex.org/W3116038682","doi":"https://doi.org/10.3390/ijms22010174","title":"Pathophysiology and Treatment of Pruritus in Elderly","display_name":"Pathophysiology and Treatment of Pruritus in Elderly","publication_year":2020,"publication_date":"2020-12-26","ids":{"openalex":"https://openalex.org/W3116038682","doi":"https://doi.org/10.3390/ijms22010174","mag":"3116038682","pmid":"https://pubmed.ncbi.nlm.nih.gov/33375325","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7795219"},"language":"en","primary_location":{"id":"doi:10.3390/ijms22010174","doi":"https://doi.org/10.3390/ijms22010174","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22010174","pdf_url":"https://www.mdpi.com/1422-0067/22/1/174/pdf?version=1609222544","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/22/1/174/pdf?version=1609222544","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068820647","display_name":"Bo Young Chung","orcid":"https://orcid.org/0000-0002-2795-0140","observed_orcids":["https://orcid.org/0000-0002-2795-0140"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Bo Young Chung","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":"https://orcid.org/0000-0002-2795-0140","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044625040","display_name":"Ji\u2010Young Um","orcid":"https://orcid.org/0000-0003-2044-199X","observed_orcids":["https://orcid.org/0000-0003-2044-199X"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Young Um","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087756402","display_name":"Jin Cheol Kim","orcid":"https://orcid.org/0000-0002-1523-6951","observed_orcids":["https://orcid.org/0000-0002-1523-6951","https://orcid.org/0000-0003-2872-8215"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jin Cheol Kim","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":"https://orcid.org/0000-0002-1523-6951","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027326191","display_name":"Seok Young Kang","orcid":"https://orcid.org/0000-0001-6532-2244","observed_orcids":["https://orcid.org/0000-0001-6532-2244"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seok Young Kang","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":"https://orcid.org/0000-0001-6532-2244","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067451446","display_name":"Chun Wook Park","orcid":"https://orcid.org/0000-0003-4512-8668","observed_orcids":["https://orcid.org/0000-0003-4512-8668"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chun Wook Park","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":"https://orcid.org/0000-0003-4512-8668","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041155675","display_name":"Hye One Kim","orcid":"https://orcid.org/0000-0001-5846-0008","observed_orcids":["https://orcid.org/0000-0001-5846-0008"]},"institutions":[{"id":"https://openalex.org/I146824383","display_name":"Hallym University","ror":"https://ror.org/03sbhge02","country_code":"KR","type":"education","lineage":["https://openalex.org/I146824383"]},{"id":"https://openalex.org/I4210094082","display_name":"Hallym University Kangnam Sacred Heart Hospital","ror":"https://ror.org/00njt2653","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210094082","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hye One Kim","raw_affiliation_strings":["Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea"],"raw_orcid":"https://orcid.org/0000-0001-5846-0008","affiliations":[{"raw_affiliation_string":"Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul KS013, Korea","institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5041155675"],"corresponding_institution_ids":["https://openalex.org/I146824383","https://openalex.org/I4210094082"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2112},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2112},"fwci":1.3451,"has_fulltext":true,"cited_by_count":87,"citation_normalized_percentile":{"value":0.79718876,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":100},"biblio":{"volume":"22","issue":"1","first_page":"174","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pruritus","display_name":"pruritus","score":0.9559999704360962},{"id":"https://openalex.org/keywords/chronic-pruritus","display_name":"chronic pruritus","score":0.8019999861717224},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9649999737739563},{"id":"https://openalex.org/keywords/senile-pruritus","display_name":"senile pruritus","score":0.859000027179718},{"id":"https://openalex.org/keywords/neuropathic-pruritus","display_name":"neuropathic pruritus","score":0.9079999923706055},{"id":"https://openalex.org/keywords/psychogenic-pruritus","display_name":"psychogenic pruritus","score":0.972000002861023},{"id":"https://openalex.org/keywords/neuronal-sensitization","display_name":"neuronal sensitization","score":0.6759999990463257},{"id":"https://openalex.org/keywords/antipruritic-agents","display_name":"antipruritic agents","score":0.8019999861717224},{"id":"https://openalex.org/keywords/topical-therapy","display_name":"topical treatment","score":0.7929999828338623},{"id":"https://openalex.org/keywords/systemic-disease","display_name":"systemic disease","score":0.49399998784065247},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8460000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8702919483184814},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.7459689378738403},{"id":"https://openalex.org/C160146798","wikidata":"https://www.wikidata.org/wiki/Q2471453","display_name":"Psychogenic disease","level":2,"score":0.6371496319770813},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4715055525302887},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4609795808792114},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.4222647547721863},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2156350016593933},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07894647121429443},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011537","descriptor_name":"Pruritus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011537","descriptor_name":"Pruritus","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019468","descriptor_name":"Disease Management","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/ijms22010174","doi":"https://doi.org/10.3390/ijms22010174","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22010174","pdf_url":"https://www.mdpi.com/1422-0067/22/1/174/pdf?version=1609222544","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:6704745","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7795219","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:33375325","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33375325","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7795219","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7795219/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:645fdfd157544dde91634da4ebf35b66","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/645fdfd157544dde91634da4ebf35b66","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, Vol 22, Iss 174, p 174 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ijms22010174","doi":"https://doi.org/10.3390/ijms22010174","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22010174","pdf_url":"https://www.mdpi.com/1422-0067/22/1/174/pdf?version=1609222544","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1182939262","display_name":null,"funder_award_id":"2017R1A2B4006252","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4025700422","display_name":null,"funder_award_id":"2018R1C1B6007998","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4643873582","display_name":null,"funder_award_id":"2020-ER6714-00","funder_id":"https://openalex.org/F4320334882","funder_display_name":"Korea Centers for Disease Control and Prevention"}],"funders":[{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"},{"id":"https://openalex.org/F4320334882","display_name":"Korea Centers for Disease Control and Prevention","ror":"https://ror.org/056za9j29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3116038682.pdf","grobid_xml":"https://content.openalex.org/works/W3116038682.grobid-xml"},"referenced_works_count":85,"referenced_works":["https://openalex.org/W88159295","https://openalex.org/W148243079","https://openalex.org/W188167072","https://openalex.org/W218292177","https://openalex.org/W1497343368","https://openalex.org/W1517354610","https://openalex.org/W1939861445","https://openalex.org/W1967800764","https://openalex.org/W1969687658","https://openalex.org/W1984215961","https://openalex.org/W1991549210","https://openalex.org/W1991879216","https://openalex.org/W1991965239","https://openalex.org/W2007464650","https://openalex.org/W2010002691","https://openalex.org/W2027590027","https://openalex.org/W2029633873","https://openalex.org/W2036650768","https://openalex.org/W2039860040","https://openalex.org/W2050146149","https://openalex.org/W2051855573","https://openalex.org/W2056183666","https://openalex.org/W2064324040","https://openalex.org/W2066046552","https://openalex.org/W2076590694","https://openalex.org/W2077790704","https://openalex.org/W2083409227","https://openalex.org/W2087340224","https://openalex.org/W2088128445","https://openalex.org/W2096349841","https://openalex.org/W2107230853","https://openalex.org/W2119228811","https://openalex.org/W2123766496","https://openalex.org/W2128057279","https://openalex.org/W2128085440","https://openalex.org/W2130894478","https://openalex.org/W2135420795","https://openalex.org/W2140123841","https://openalex.org/W2145468167","https://openalex.org/W2160068319","https://openalex.org/W2168499550","https://openalex.org/W2172019803","https://openalex.org/W2172111914","https://openalex.org/W2249576348","https://openalex.org/W2339791033","https://openalex.org/W2401879669","https://openalex.org/W2441719627","https://openalex.org/W2464631818","https://openalex.org/W2465799764","https://openalex.org/W2503551646","https://openalex.org/W2510220995","https://openalex.org/W2593200577","https://openalex.org/W2732340271","https://openalex.org/W2735601046","https://openalex.org/W2748614145","https://openalex.org/W2752706812","https://openalex.org/W2755290839","https://openalex.org/W2766286430","https://openalex.org/W2776648429","https://openalex.org/W2787696154","https://openalex.org/W2789024274","https://openalex.org/W2789906712","https://openalex.org/W2792138631","https://openalex.org/W2793414547","https://openalex.org/W2795847976","https://openalex.org/W2802358214","https://openalex.org/W2882994752","https://openalex.org/W2884812951","https://openalex.org/W2888678158","https://openalex.org/W2909482080","https://openalex.org/W2925154616","https://openalex.org/W2925431145","https://openalex.org/W2943210193","https://openalex.org/W2956083130","https://openalex.org/W2970348403","https://openalex.org/W2978096514","https://openalex.org/W2981594246","https://openalex.org/W2991540591","https://openalex.org/W2993290426","https://openalex.org/W2999398470","https://openalex.org/W3004398344","https://openalex.org/W3037519792","https://openalex.org/W3096592481","https://openalex.org/W4245249307","https://openalex.org/W4252643230"],"related_works":["https://openalex.org/W4387610100","https://openalex.org/W4255487781","https://openalex.org/W2550753586","https://openalex.org/W2766286430","https://openalex.org/W2187317610","https://openalex.org/W6948850433","https://openalex.org/W4398239931","https://openalex.org/W1970388928","https://openalex.org/W2515256482","https://openalex.org/W617824596"],"abstract_inverted_index":{"Pruritus":[0,23],"is":[1,17,45,53],"a":[2,33,92],"relatively":[3],"common":[4,19],"symptom":[5],"that":[6],"anyone":[7],"can":[8,26,57,88],"experience":[9],"at":[10,106],"any":[11],"point":[12],"in":[13,20,24,32,43,98,119],"their":[14],"life":[15,52],"and":[16,48,82,110,114,130,142],"more":[18],"the":[21,49,120],"elderly.":[22],"elderly":[25,44,99],"be":[27,58,89],"defined":[28,90],"as":[29,91],"chronic":[30,93],"pruritus":[31,42,78,87,94],"person":[34],"over":[35],"65":[36],"years":[37],"old.":[38],"The":[39],"pathophysiology":[40],"of":[41,51,95,126],"still":[46],"unclear,":[47],"quality":[50],"reduced.":[54],"Generally,":[55],"itch":[56,69],"clinically":[59],"classified":[60],"into":[61],"six":[62],"types:":[63],"Itch":[64],"caused":[65,70],"by":[66,71],"systemic":[67,141],"diseases,":[68,73],"skin":[72],"neuropathic":[74],"pruritus,":[75,77],"psychogenic":[76],"with":[79],"multiple":[80],"factors,":[81],"from":[83],"unknown":[84,96],"causes.":[85],"Senile":[86],"origin":[97],"people.":[100],"Various":[101],"neuronal":[102,107,115],"mediators,":[103],"signaling":[104],"mechanisms":[105],"terminals,":[108],"central":[109],"peripheral":[111],"neurotransmission":[112],"pathways,":[113],"sensitizations":[116],"are":[117,128,134],"included":[118],"processes":[121],"causing":[122],"itch.":[123],"A":[124],"variety":[125],"therapies":[127],"used":[129],"several":[131],"novel":[132],"drugs":[133],"being":[135],"developed":[136],"to":[137],"relieve":[138],"itch,":[139],"including":[140],"topical":[143],"treatments.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":21},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-01-05T00:00:00"}