{"id":"https://openalex.org/W3113634883","doi":"https://doi.org/10.1186/s13568-021-01205-9","title":"Optimizing the acceleration of Cheddar cheese ripening using response surface methodology by microbial protease without altering its quality features","display_name":"Optimizing the acceleration of Cheddar cheese ripening using response surface methodology by microbial protease without altering its quality features","publication_year":2021,"publication_date":"2021-03-22","ids":{"openalex":"https://openalex.org/W3113634883","doi":"https://doi.org/10.1186/s13568-021-01205-9","mag":"3113634883","pmid":"https://pubmed.ncbi.nlm.nih.gov/33751265","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7984165"},"language":"en","primary_location":{"id":"doi:10.1186/s13568-021-01205-9","doi":"https://doi.org/10.1186/s13568-021-01205-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13568-021-01205-9","pdf_url":"https://amb-express.springeropen.com/counter/pdf/10.1186/s13568-021-01205-9","source":{"id":"https://openalex.org/S129630946","display_name":"AMB Express","issn_l":"2191-0855","issn":["2191-0855"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMB Express","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://amb-express.springeropen.com/counter/pdf/10.1186/s13568-021-01205-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008505460","display_name":"Amaal Mohammed Alhelli","orcid":"https://orcid.org/0000-0002-2267-8854","observed_orcids":["https://orcid.org/0000-0002-2267-8854"]},"institutions":[{"id":"https://openalex.org/I4210115078","display_name":"Middle Technical University","ror":"https://ror.org/02fvkg758","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4210115078"]}],"countries":["IQ"],"is_corresponding":true,"raw_author_name":"Amaal Mohammed Alhelli","raw_affiliation_strings":["Department of Water Resource Technique, Institute of Technology, Middle Technical University, Alzafaranya, Baghdad, 29008, Iraq. amaalalhelli@yahoo.com","Department of Water Resource Technique, Institute of Technology, Middle Technical University, Alzafaranya, Baghdad, 29008, Iraq"],"raw_orcid":"https://orcid.org/0000-0002-2267-8854","affiliations":[{"raw_affiliation_string":"Department of Water Resource Technique, Institute of Technology, Middle Technical University, Alzafaranya, Baghdad, 29008, Iraq. amaalalhelli@yahoo.com","institution_ids":["https://openalex.org/I4210115078"]},{"raw_affiliation_string":"Department of Water Resource Technique, Institute of Technology, Middle Technical University, Alzafaranya, Baghdad, 29008, Iraq","institution_ids":["https://openalex.org/I4210115078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066844105","display_name":"Nameer Khairullah Mohammed","orcid":"https://orcid.org/0000-0002-9202-0281","observed_orcids":["https://orcid.org/0000-0002-9202-0281"]},"institutions":[{"id":"https://openalex.org/I72539421","display_name":"University of Tikrit","ror":"https://ror.org/01zfzax10","country_code":"IQ","type":"education","lineage":["https://openalex.org/I72539421"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Nameer Khairulla Mohammed","raw_affiliation_strings":["Food Science and Biotechnology Department, Faculty of Agriculture, Tikrit Uiversity, Tikrit, 34001, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food Science and Biotechnology Department, Faculty of Agriculture, Tikrit Uiversity, Tikrit, 34001, Iraq","institution_ids":["https://openalex.org/I72539421"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030074629","display_name":"Eilaf Suliman Khalil","orcid":"https://orcid.org/0000-0001-8073-9187","observed_orcids":["https://orcid.org/0000-0001-8073-9187"]},"institutions":[{"id":"https://openalex.org/I150406212","display_name":"University of Khartoum","ror":"https://ror.org/02jbayz55","country_code":"SD","type":"education","lineage":["https://openalex.org/I150406212"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Eilaf Suliman Khalil","raw_affiliation_strings":["Department of Dairy Production, Faculty of Animal Production, University of Khartoum, Khartoum, Sudan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dairy Production, Faculty of Animal Production, University of Khartoum, Khartoum, Sudan","institution_ids":["https://openalex.org/I150406212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039312568","display_name":"Anis Shobirin Meor Hussin","orcid":"https://orcid.org/0000-0002-9702-8856","observed_orcids":["https://orcid.org/0000-0002-9702-8856"]},"institutions":[{"id":"https://openalex.org/I130343225","display_name":"Universiti Putra Malaysia","ror":"https://ror.org/02e91jd64","country_code":"MY","type":"education","lineage":["https://openalex.org/I130343225"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Anis Shobirin Meor Hussin","raw_affiliation_strings":["Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia","Halal Products Research Institute, University Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia","institution_ids":["https://openalex.org/I130343225"]},{"raw_affiliation_string":"Halal Products Research Institute, University Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia","institution_ids":["https://openalex.org/I130343225"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008505460"],"corresponding_institution_ids":["https://openalex.org/I4210115078"],"apc_list":{"value":2390,"currency":"USD","value_usd":2390},"apc_paid":{"value":2390,"currency":"USD","value_usd":2390},"fwci":1.3622,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.76676946,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"11","issue":"1","first_page":"45","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14438","display_name":"Advanced Scientific Research Methods","score":0.5928000211715698,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14438","display_name":"Advanced Scientific Research Methods","score":0.5928000211715698,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.11190000176429749,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.053700000047683716,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cheddar-cheese","display_name":"Cheddar cheese","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cheese-ripening","display_name":"cheese ripening","score":0.7799999713897705},{"id":"https://openalex.org/keywords/accelerated-ripening","display_name":"accelerated ripening","score":0.8009999990463257},{"id":"https://openalex.org/keywords/microbial-proteases","display_name":"microbial proteases","score":0.8330000042915344},{"id":"https://openalex.org/keywords/penicillium-candidum","display_name":"Penicillium candidum","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cheese-proteolysis","display_name":"cheese proteolysis","score":0.7590000033378601},{"id":"https://openalex.org/keywords/cheese-curd","display_name":"cheese curd","score":0.7570000290870667},{"id":"https://openalex.org/keywords/cheese-quality","display_name":"cheese quality","score":0.6909999847412109},{"id":"https://openalex.org/keywords/water-activity","display_name":"water activity","score":0.7279999852180481},{"id":"https://openalex.org/keywords/soluble-nitrogen","display_name":"soluble nitrogen","score":0.6830000281333923},{"id":"https://openalex.org/keywords/sensory-acceptance","display_name":"sensory acceptability","score":0.7250000238418579},{"id":"https://openalex.org/keywords/amino-acids","display_name":"amino acids","score":0.7009999752044678},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C150077022","wikidata":"https://www.wikidata.org/wiki/Q3136137","display_name":"Response surface methodology","level":2,"score":0.8102178573608398},{"id":"https://openalex.org/C172353545","wikidata":"https://www.wikidata.org/wiki/Q2121926","display_name":"Ripening","level":2,"score":0.7845891118049622},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.7543723583221436},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.7336928248405457},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.605320930480957},{"id":"https://openalex.org/C2780563676","wikidata":"https://www.wikidata.org/wiki/Q1758872","display_name":"Aroma","level":2,"score":0.5893558859825134},{"id":"https://openalex.org/C2779389801","wikidata":"https://www.wikidata.org/wiki/Q2826073","display_name":"Cheese ripening","level":3,"score":0.49537956714630127},{"id":"https://openalex.org/C2781307694","wikidata":"https://www.wikidata.org/wiki/Q33123","display_name":"Proteolysis","level":3,"score":0.45049890875816345},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2942979335784912},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.28990796208381653},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.25521546602249146}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1186/s13568-021-01205-9","doi":"https://doi.org/10.1186/s13568-021-01205-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13568-021-01205-9","pdf_url":"https://amb-express.springeropen.com/counter/pdf/10.1186/s13568-021-01205-9","source":{"id":"https://openalex.org/S129630946","display_name":"AMB Express","issn_l":"2191-0855","issn":["2191-0855"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMB Express","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-124596/v1","doi":"https://doi.org/10.21203/rs.3.rs-124596/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-124596/v1","pdf_url":"https://www.researchsquare.com/article/rs-124596/v1.pdf?c=1631880969000","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:33751265","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33751265","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMB Express","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7984165","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7984165/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMB Express","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:15289e6454fc4f258d45f4a98c0551fd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/15289e6454fc4f258d45f4a98c0551fd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AMB Express, Vol 11, Iss 1, Pp 1-13 (2021)","raw_type":"article"},{"id":"pmh:oai:psasir.upm.edu.my:94470","doi":null,"is_oa":true,"landing_page_url":"https://amb-express.springeropen.com/articles/10.1186/s13568-021-01205-9#:~:text=The%20optimal%20acceleration%20Cheddar%20cheese,time%20of%200.6%2F3%20months.","pdf_url":null,"source":{"id":"https://openalex.org/S4377196260","display_name":"Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I130343225","host_organization_name":"Universiti Putra Malaysia","host_organization_lineage":["https://openalex.org/I130343225"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/s13568-021-01205-9","doi":"https://doi.org/10.1186/s13568-021-01205-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13568-021-01205-9","pdf_url":"https://amb-express.springeropen.com/counter/pdf/10.1186/s13568-021-01205-9","source":{"id":"https://openalex.org/S129630946","display_name":"AMB Express","issn_l":"2191-0855","issn":["2191-0855"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMB Express","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.40450000762939453,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3113634883.pdf","grobid_xml":"https://content.openalex.org/works/W3113634883.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W130903100","https://openalex.org/W1029599082","https://openalex.org/W1493178216","https://openalex.org/W1799704707","https://openalex.org/W1946935088","https://openalex.org/W1964764457","https://openalex.org/W1969721405","https://openalex.org/W1971421288","https://openalex.org/W1982335181","https://openalex.org/W1993828703","https://openalex.org/W1994626400","https://openalex.org/W1995290689","https://openalex.org/W1996155952","https://openalex.org/W1999871381","https://openalex.org/W2008591424","https://openalex.org/W2028130178","https://openalex.org/W2038543375","https://openalex.org/W2044796417","https://openalex.org/W2051451783","https://openalex.org/W2051607826","https://openalex.org/W2053634455","https://openalex.org/W2060842280","https://openalex.org/W2061383114","https://openalex.org/W2065614206","https://openalex.org/W2069933509","https://openalex.org/W2080589224","https://openalex.org/W2080771869","https://openalex.org/W2103744834","https://openalex.org/W2107038117","https://openalex.org/W2108095780","https://openalex.org/W2119436581","https://openalex.org/W2132769012","https://openalex.org/W2151712308","https://openalex.org/W2154854625","https://openalex.org/W2159325042","https://openalex.org/W2255822954","https://openalex.org/W2262949377","https://openalex.org/W2343000587","https://openalex.org/W2414361397","https://openalex.org/W2489959234","https://openalex.org/W2512514802","https://openalex.org/W2555528203","https://openalex.org/W2572175701","https://openalex.org/W2770212912","https://openalex.org/W2794345673","https://openalex.org/W2799945659","https://openalex.org/W2887737246","https://openalex.org/W2902884194","https://openalex.org/W2922236262","https://openalex.org/W2955790376","https://openalex.org/W2965880310","https://openalex.org/W2970966573","https://openalex.org/W2988196033","https://openalex.org/W2989961886","https://openalex.org/W3001478469","https://openalex.org/W3005077438","https://openalex.org/W3016392149","https://openalex.org/W3033310254","https://openalex.org/W3045180612","https://openalex.org/W3083318878"],"related_works":["https://openalex.org/W6958095479","https://openalex.org/W6958295957","https://openalex.org/W1971421288","https://openalex.org/W874965125","https://openalex.org/W2029158236","https://openalex.org/W2025148233","https://openalex.org/W2143769709","https://openalex.org/W7134257577","https://openalex.org/W84374066","https://openalex.org/W2053191677"],"abstract_inverted_index":{"Abstract":[0],"Cheddar":[1,45,80,120,152],"cheese":[2,12,46,153],"proteolysis":[3],"were":[4,34,105,128],"accelerated":[5,44],"employing":[6],"Penicillium":[7],"candidum":[8],"PCA1/TT031":[9],"protease":[10,25,29,54],"into":[11],"curd.":[13],"In":[14,142],"the":[15,20,37,71,76,86,123,134,139,145,148,155,166],"present":[16],"study,":[17],"several":[18],"of":[19,49,78,118,138,144,157,159],"significant":[21,130,173],"factors":[22],"such":[23],"as":[24],"purification":[26],"factor":[27],"(PF),":[28],"concentration":[30,55,156],"and":[31,56,102,115,125,136,150,162],"ripening":[32,59],"time":[33,60],"optimized":[35],"via":[36],"response":[38],"surface":[39],"methodology":[40,74],"(RSM).":[41],"The":[42,64],"ideal":[43,119,149],"environment":[47],"consisted":[48],"3.12":[50],"PF,":[51],"0.01%":[52],"(v/v)":[53],"0.6/3":[57],"months":[58],"at":[61],"10":[62],"\u00b0C.":[63],"RSM":[65],"models":[66],"was":[67],"verified":[68],"to":[69,107],"be":[70,108],"most":[72],"proper":[73],"for":[75],"maintain":[77],"chosen":[79],"cheese.":[81,121],"Under":[82],"this":[83],"experimental":[84,126],"environment,":[85],"pH,":[87],"acid":[88],"degree":[89],"value":[90],"(ADV),":[91],"moisture,":[92],"water":[93],"activity":[94],"(a":[95],"w":[96],"),":[97],"soluble":[98],"nitrogen":[99],"(SN)%,":[100],"fat":[101],"overall":[103],"acceptability":[104],"found":[106],"5.4,":[109],"6.6,":[110],"35%,":[111],"0.9348,":[112],"18.8%,":[113],"34%":[114],"13.6,":[116],"respectively":[117],"Furthermore,":[122],"predicted":[124],"results":[127],"in":[129,154,175],"agreement,":[131],"which":[132],"confirmed":[133],"validity":[135],"reliability":[137],"suggested":[140],"method.":[141],"spite":[143],"difference":[146,174],"between":[147,178],"commercial":[151],"some":[158],"amino":[160],"acids":[161],"free":[163],"fatty":[164],"acids,":[165],"sensory":[167],"evaluation":[168],"did":[169],"not":[170],"show":[171],"any":[172],"aroma":[176],"profile":[177],"them.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2021-01-05T00:00:00"}