{"id":"https://openalex.org/W3109065612","doi":"https://doi.org/10.18632/aging.202302","title":"A model integrating donor gene polymorphisms predicts fibrosis after liver transplantation","display_name":"A model integrating donor gene polymorphisms predicts fibrosis after liver transplantation","publication_year":2020,"publication_date":"2020-12-03","ids":{"openalex":"https://openalex.org/W3109065612","doi":"https://doi.org/10.18632/aging.202302","mag":"3109065612","pmid":"https://pubmed.ncbi.nlm.nih.gov/33291080","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7835018"},"language":"en","primary_location":{"id":"doi:10.18632/aging.202302","doi":"https://doi.org/10.18632/aging.202302","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.202302","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC7835018","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100407178","display_name":"Chao Wang","orcid":"https://orcid.org/0009-0009-5719-3628","observed_orcids":["https://orcid.org/0009-0009-5719-3628"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Wang","raw_affiliation_strings":["Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"NHC Key Laboratory of Combined Multi-Organ Transplantation, Hangzhou 310003, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000699315","display_name":"Xueyou Zhang","orcid":"https://orcid.org/0000-0001-9635-517X","observed_orcids":["https://orcid.org/0000-0001-9635-517X"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueyou Zhang","raw_affiliation_strings":["Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002132621","display_name":"Qi Ling","orcid":"https://orcid.org/0000-0002-7377-2381","observed_orcids":["https://orcid.org/0000-0002-7377-2381"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Ling","raw_affiliation_strings":["Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100654810","display_name":"Shusen Zheng","orcid":"https://orcid.org/0000-0003-1459-8261","observed_orcids":["https://orcid.org/0000-0003-1459-8261"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shusen Zheng","raw_affiliation_strings":["Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101135156","display_name":"Xiao Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiao Xu","raw_affiliation_strings":["Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China","institution_ids":["https://openalex.org/I4210166576"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100654810","https://openalex.org/A5101135156"],"corresponding_institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":2.0506,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.8728376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"13","issue":"1","first_page":"1264","last_page":"1275"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.972000002861023},{"id":"https://openalex.org/keywords/grp78","display_name":"GRP78","score":0.7459999918937683},{"id":"https://openalex.org/keywords/gstp1","display_name":"GSTP1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8629999756813049},{"id":"https://openalex.org/keywords/tacrolimus","display_name":"tacrolimus","score":0.8619999885559082},{"id":"https://openalex.org/keywords/post-transplant-diabetes-mellitus","display_name":"post-transplant diabetes mellitus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-model","display_name":"prognostic model","score":0.8989999890327454}],"concepts":[{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.6771615743637085},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5088174939155579},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4622710645198822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4312407970428467},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4051055610179901},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.37656939029693604},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34752482175827026},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.320620596408844},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22784897685050964}],"mesh":[{"descriptor_ui":"D000091342","descriptor_name":"Endoplasmic Reticulum Chaperone BiP","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014019","descriptor_name":"Tissue Donors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016031","descriptor_name":"Liver Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016559","descriptor_name":"Tacrolimus","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016559","descriptor_name":"Tacrolimus","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017114","descriptor_name":"Liver Failure, Acute","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051549","descriptor_name":"Glutathione S-Transferase pi","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.18632/aging.202302","doi":"https://doi.org/10.18632/aging.202302","is_oa":false,"landing_page_url":"https://doi.org/10.18632/aging.202302","pdf_url":null,"source":{"id":"https://openalex.org/S4210231119","display_name":"Aging","issn_l":"1945-4589","issn":["1945-4589"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316297","host_organization_name":"Impact Journals LLC","host_organization_lineage":["https://openalex.org/P4310316297"],"host_organization_lineage_names":["Impact Journals LLC"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:6762880","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7835018","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7835018","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7835018","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging (Albany NY)","raw_type":"Text"},{"id":"pmid:33291080","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33291080","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:6762880","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7835018","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1489303745","https://openalex.org/W1604329390","https://openalex.org/W1876174007","https://openalex.org/W1882102609","https://openalex.org/W1976930022","https://openalex.org/W1982249882","https://openalex.org/W1985108168","https://openalex.org/W1987192397","https://openalex.org/W1990997223","https://openalex.org/W1997619053","https://openalex.org/W1997865776","https://openalex.org/W2009987800","https://openalex.org/W2014672393","https://openalex.org/W2022598362","https://openalex.org/W2024877521","https://openalex.org/W2026082182","https://openalex.org/W2030576387","https://openalex.org/W2030702176","https://openalex.org/W2040712791","https://openalex.org/W2041438772","https://openalex.org/W2053193232","https://openalex.org/W2057105752","https://openalex.org/W2061921344","https://openalex.org/W2064387090","https://openalex.org/W2092104787","https://openalex.org/W2097093560","https://openalex.org/W2100901996","https://openalex.org/W2107921406","https://openalex.org/W2112368754","https://openalex.org/W2118737336","https://openalex.org/W2128548864","https://openalex.org/W2154780832","https://openalex.org/W2183229271","https://openalex.org/W2411379087","https://openalex.org/W2411447384","https://openalex.org/W2608293540","https://openalex.org/W2766887070","https://openalex.org/W2889191411","https://openalex.org/W2910086273","https://openalex.org/W2972397811","https://openalex.org/W4210986718"],"related_works":["https://openalex.org/W2197816205","https://openalex.org/W3013483660","https://openalex.org/W4399899686","https://openalex.org/W4408482266","https://openalex.org/W2167661626","https://openalex.org/W2502468059","https://openalex.org/W4236853326","https://openalex.org/W4410333674","https://openalex.org/W4406389917","https://openalex.org/W2105220863"],"abstract_inverted_index":{"Post-transplant":[0],"liver":[1,11,22,35,46],"fibrosis":[2,47],"(PTLF)":[3],"is":[4],"a":[5,62,143],"common":[6],"and":[7,98,119],"severe":[8],"complication":[9],"in":[10],"recipients.":[12],"In":[13,61],"this":[14,169],"study,":[15],"we":[16],"assessed":[17],"the":[18,25],"impact":[19],"of":[20,27,31,68,73,167],"donor":[21,54,74,134,158,173],"genetics":[23],"on":[24],"development":[26],"PTLF.":[28,60,180],"A":[29,129],"total":[30],"232":[32],"patients":[33],"undergoing":[34],"transplantation":[36],"were":[37,48,70],"included.":[38],"Twenty-two":[39],"single":[40],"nucleotide":[41],"polymorphisms":[42,175],"(SNPs)":[43],"associated":[44,58,162],"with":[45,59,145,163,172],"analyzed.":[49],"Univariate":[50],"analysis":[51],"revealed":[52],"seven":[53],"SNPs":[55,135,160],"to":[56],"be":[57],"multivariate":[63],"analysis,":[64],"independent":[65],"risk":[66,166],"factors":[67],"PTLF":[69,141],"genetic":[71],"variation":[72],"GRP78":[75],"rs430397":[76],"(OR":[77,85,93,101,115,123],"=":[78,81,86,89,94,102,105,124,127],"8.99,":[79],"p":[80,88,96,104,117,126],"0.003),":[82],"GSTP1":[83],"rs1695":[84],"0.13,":[87],"0.021),":[90],"miRNA-196a":[91],"rs12304647":[92],"16.01,":[95],"=0.001),":[97],"TNF-\u03b1":[99],"rs1800630":[100],"79.78,":[103],"0.001);":[106],"blood":[107],"tacrolimus":[108],"levels":[109],"at":[110],"maintenance":[111],">":[112],"7":[113],"ng/ml":[114],"=7.48,":[116],"<0.001);":[118],"post-transplant":[120],"diabetes":[121],"mellitus":[122],"7.50,":[125],"0.001).":[128,155],"predictive":[130],"model":[131,144,170],"that":[132,157],"included":[133],"showed":[136],"better":[137],"prognostic":[138],"ability":[139],"for":[140],"than":[142],"only":[146],"clinical":[147],"parameters":[148],"(AUROC:":[149],"0.863":[150],"vs":[151],"0.707,":[152],"P":[153],"<":[154],"Given":[156],"gene":[159,174],"are":[161],"an":[164],"increased":[165],"PTLF,":[168],"integrated":[171],"may":[176],"help":[177],"clinicians":[178],"predict":[179]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-12-07T00:00:00"}