{"id":"https://openalex.org/W3106573019","doi":null,"title":"Gene Expression Changes Mediated by IL6 Trans-signaling in Human Retinal Endothelial Cells.","display_name":"Gene Expression Changes Mediated by IL6 Trans-signaling in Human Retinal Endothelial Cells.","publication_year":2020,"publication_date":"2020-06-10","ids":{"openalex":"https://openalex.org/W3106573019","mag":"3106573019"},"language":"en","primary_location":{"id":"mag:3106573019","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2766708","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://iovs.arvojournals.org/article.aspx?articleid=2766708","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049498138","display_name":"Shruti Sharma","orcid":"https://orcid.org/0000-0001-8200-108X","observed_orcids":["https://orcid.org/0000-0001-8200-108X"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shruti Sharma","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069805409","display_name":"Lara Churchwell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lara Churchwell","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033998113","display_name":"Daria Brown","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daria Brown","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tae Jin Lee","orcid":"https://orcid.org/0000-0002-5245-1140","observed_orcids":["https://orcid.org/0000-0002-5245-1140"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tae Jin Lee","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":"https://orcid.org/0000-0002-5245-1140","affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087617552","display_name":"Sai Karthik Kodeboyina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sai Karthik Kodeboyina","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112052379","display_name":"Justin Bloom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin Bloom","raw_affiliation_strings":["Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biotechnology and Genomic Med, Medical College of Georgia, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002893934","display_name":"Ashok Kumar Sharma","orcid":"https://orcid.org/0000-0001-9597-4374","observed_orcids":["https://orcid.org/0000-0001-9597-4374"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashok Sharma","raw_affiliation_strings":["Department of Population Health Sciences, Augusta University, Augusta, Georgia, United States"],"raw_orcid":"https://orcid.org/0000-0001-9597-4374","affiliations":[{"raw_affiliation_string":"Department of Population Health Sciences, Augusta University, Augusta, Georgia, United States","institution_ids":["https://openalex.org/I25041050"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I25041050"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.17120115,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"61","issue":"7","first_page":"748","last_page":"748"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.8711000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.8711000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.07779999822378159,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9039999842643738},{"id":"https://openalex.org/keywords/retinal-endothelial-cells","display_name":"retinal endothelial cells","score":0.8629999756813049},{"id":"https://openalex.org/keywords/gene-expression-changes","display_name":"gene expression changes","score":0.8610000014305115},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.36000001430511475},{"id":"https://openalex.org/keywords/retinal-disease","display_name":"retinal disease","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.741226315498352},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5443326234817505},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48743656277656555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41195178031921387},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41123417019844055},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29453134536743164},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05189266800880432}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3106573019","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2766708","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":{"id":"mag:3106573019","doi":null,"is_oa":true,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2766708","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3212528794","https://openalex.org/W3115418976","https://openalex.org/W4366985561","https://openalex.org/W2918339687","https://openalex.org/W1141539674","https://openalex.org/W1139755755","https://openalex.org/W2914612863","https://openalex.org/W984201184","https://openalex.org/W1262499219","https://openalex.org/W996180947"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-12-07T00:00:00"}