{"id":"https://openalex.org/W3106029068","doi":"https://doi.org/10.1007/s13300-020-00959-y","title":"Long-Term Cost-Effectiveness the Dexcom G6 Real-Time Continuous Glucose Monitoring System Compared with Self-Monitoring of Blood Glucose in People with Type 1 Diabetes in France","display_name":"Long-Term Cost-Effectiveness the Dexcom G6 Real-Time Continuous Glucose Monitoring System Compared with Self-Monitoring of Blood Glucose in People with Type 1 Diabetes in France","publication_year":2020,"publication_date":"2020-11-09","ids":{"openalex":"https://openalex.org/W3106029068","doi":"https://doi.org/10.1007/s13300-020-00959-y","mag":"3106029068","pmid":"https://pubmed.ncbi.nlm.nih.gov/33165838","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7651823"},"language":"en","primary_location":{"id":"doi:10.1007/s13300-020-00959-y","doi":"https://doi.org/10.1007/s13300-020-00959-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13300-020-00959-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13300-020-00959-y.pdf","source":{"id":"https://openalex.org/S16535137","display_name":"Diabetes Therapy","issn_l":"1869-6961","issn":["1869-6961","1869-6953"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1007/s13300-020-00959-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108729560","display_name":"St\u00e9phane Roze","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"St\u00e9phane Roze","raw_affiliation_strings":["Vyoo Agency, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vyoo Agency, Lyon, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033689655","display_name":"John J. Isitt","orcid":"https://orcid.org/0000-0003-1854-8798","observed_orcids":["https://orcid.org/0000-0003-1854-8798"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John J. Isitt","raw_affiliation_strings":["Vyoo Agency, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vyoo Agency, Lyon, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019471615","display_name":"Jayne Smith\u2010Palmer","orcid":"https://orcid.org/0000-0001-6049-1241","observed_orcids":["https://orcid.org/0000-0001-6049-1241"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jayne Smith-Palmer","raw_affiliation_strings":["Ossian Health Economics and Communications, Basel, Switzerland. smith-palmer@ossianconsulting.com","Ossian Health Economics and Communications, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ossian Health Economics and Communications, Basel, Switzerland. smith-palmer@ossianconsulting.com","institution_ids":[]},{"raw_affiliation_string":"Ossian Health Economics and Communications, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086318356","display_name":"Peter Matthew Lynch","orcid":"https://orcid.org/0000-0002-4278-5200","observed_orcids":["https://orcid.org/0000-0002-4278-5200"]},"institutions":[{"id":"https://openalex.org/I4210138524","display_name":"Dexcom (United States)","ror":"https://ror.org/03ra42c27","country_code":"US","type":"company","lineage":["https://openalex.org/I4210138524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Lynch","raw_affiliation_strings":["Dexcom, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dexcom, San Diego, CA, USA","institution_ids":["https://openalex.org/I4210138524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010038291","display_name":"Brigitte Klinkenbijl","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brigitte Klinkenbijl","raw_affiliation_strings":["Dexcom, Essertines-sur-Rolle, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dexcom, Essertines-sur-Rolle, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027704383","display_name":"G\u00e9rald Zammit","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerald Zammit","raw_affiliation_strings":["Dexcom, Reading, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dexcom, Reading, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081436718","display_name":"Pierre\u2010Yves Benhamou","orcid":"https://orcid.org/0000-0003-4378-0468","observed_orcids":["https://orcid.org/0000-0003-4378-0468"]},"institutions":[{"id":"https://openalex.org/I2800555055","display_name":"Centre Hospitalier Universitaire de Grenoble","ror":"https://ror.org/041rhpw39","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I2800555055"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre-Yves Benhamou","raw_affiliation_strings":["Department of Endocrinology, Grenoble Alpes University Hospital, Grenoble, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Grenoble Alpes University Hospital, Grenoble, France","institution_ids":["https://openalex.org/I2800555055"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019471615"],"corresponding_institution_ids":[],"apc_list":{"value":5899,"currency":"USD","value_usd":5899},"apc_paid":{"value":5899,"currency":"USD","value_usd":5899},"fwci":1.8112,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.84626827,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"235","last_page":"246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.09989999979734421,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dexcom-g6","display_name":"Dexcom G6","score":0.9020000100135803},{"id":"https://openalex.org/keywords/real-time-continuous-glucose-monitoring","display_name":"real-time continuous glucose monitoring","score":0.9300000071525574},{"id":"https://openalex.org/keywords/self-monitoring-of-blood-glucose","display_name":"self-monitoring of blood glucose","score":0.9390000104904175},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":1.0},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.9909999966621399},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.8790000081062317},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7889999747276306},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.8399999737739563},{"id":"https://openalex.org/keywords/fear-of-hypoglycemia","display_name":"fear of hypoglycemia","score":0.925000011920929},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8561873435974121},{"id":"https://openalex.org/C2777580121","wikidata":"https://www.wikidata.org/wiki/Q5450300","display_name":"Fingerstick","level":3,"score":0.8488574624061584},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.7032492160797119},{"id":"https://openalex.org/C2986379492","wikidata":"https://www.wikidata.org/wiki/Q1638492","display_name":"Continuous glucose monitoring","level":4,"score":0.5926143527030945},{"id":"https://openalex.org/C2778097690","wikidata":"https://www.wikidata.org/wiki/Q5413797","display_name":"Euros","level":2,"score":0.5674958825111389},{"id":"https://openalex.org/C2780668416","wikidata":"https://www.wikidata.org/wiki/Q202758","display_name":"Hypoglycemia","level":3,"score":0.5046085119247437},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.5013425350189209},{"id":"https://openalex.org/C64332521","wikidata":"https://www.wikidata.org/wiki/Q614165","display_name":"Quality-adjusted life year","level":3,"score":0.4689951241016388},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4446500241756439},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.43306106328964233},{"id":"https://openalex.org/C2908918659","wikidata":"https://www.wikidata.org/wiki/Q4927806","display_name":"Blood Glucose Self-Monitoring","level":5,"score":0.41637134552001953},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.40697821974754333},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.12999531626701355},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.060043007135391235},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s13300-020-00959-y","doi":"https://doi.org/10.1007/s13300-020-00959-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13300-020-00959-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13300-020-00959-y.pdf","source":{"id":"https://openalex.org/S16535137","display_name":"Diabetes Therapy","issn_l":"1869-6961","issn":["1869-6961","1869-6953"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Therapy","raw_type":"journal-article"},{"id":"pmid:33165838","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33165838","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes therapy : research, treatment and education of diabetes and related disorders","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7651823","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7651823/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Ther","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s13300-020-00959-y","doi":"https://doi.org/10.1007/s13300-020-00959-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13300-020-00959-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13300-020-00959-y.pdf","source":{"id":"https://openalex.org/S16535137","display_name":"Diabetes Therapy","issn_l":"1869-6961","issn":["1869-6961","1869-6953"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316051","display_name":"Dexcom","ror":"https://ror.org/03ra42c27"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3106029068.pdf","grobid_xml":"https://content.openalex.org/works/W3106029068.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W83948060","https://openalex.org/W1500347834","https://openalex.org/W1975214916","https://openalex.org/W1980913786","https://openalex.org/W1987844190","https://openalex.org/W1991586295","https://openalex.org/W1997475443","https://openalex.org/W2020572030","https://openalex.org/W2038962843","https://openalex.org/W2081872797","https://openalex.org/W2088337461","https://openalex.org/W2094748369","https://openalex.org/W2110019707","https://openalex.org/W2112537103","https://openalex.org/W2131649684","https://openalex.org/W2133427837","https://openalex.org/W2169355652","https://openalex.org/W2190078402","https://openalex.org/W2208450501","https://openalex.org/W2582943213","https://openalex.org/W2604156892","https://openalex.org/W2625008240","https://openalex.org/W2762706874","https://openalex.org/W2767259825","https://openalex.org/W2791784198","https://openalex.org/W2883817914","https://openalex.org/W2898920858","https://openalex.org/W2924516949","https://openalex.org/W2946761605","https://openalex.org/W3017387078","https://openalex.org/W3025666376"],"related_works":["https://openalex.org/W3193000380","https://openalex.org/W3041726884","https://openalex.org/W4221039340","https://openalex.org/W4381158201","https://openalex.org/W4390979973","https://openalex.org/W4307092552","https://openalex.org/W4307093171","https://openalex.org/W2737396510","https://openalex.org/W4306743903","https://openalex.org/W2765091416"],"abstract_inverted_index":{"INTRODUCTION:":[0],"The":[1,35,123],"aim":[2],"was":[3,37,119,127],"to":[4,63,79,202],"determine":[5],"the":[6,10,40,51,74,90,110,116,192,195,216,226],"long-term":[7],"cost-effectiveness":[8,170],"of":[9,21,69,84,95,104,109,137,172,186,194,225],"Dexcom":[11],"G6":[12,124,196],"real-time":[13],"continuous":[14],"glucose":[15,23],"monitoring":[16],"(RT-CGM)":[17],"system":[18,126,198],"versus":[19,148,163],"self-monitoring":[20],"blood":[22],"(SMBG)":[24],"in":[25,32,55,73,89,115,133,167],"adults":[26,56,205],"with":[27,57,87,100,129,144,159,206,220],"type":[28],"1":[29],"diabetes":[30],"(T1D)":[31],"France.":[33],"METHODS:":[34],"analysis":[36],"performed":[38],"using":[39],"IQVIA":[41],"Core":[42],"Diabetes":[43],"Model":[44],"and":[45,71,107,215,223],"utilized":[46],"clinical":[47,53],"input":[48],"data":[49],"from":[50],"DIAMOND":[52],"trial":[54],"T1D.":[58],"Simulated":[59],"patients":[60],"were":[61,77,155],"assumed":[62,78],"have":[64,80],"a":[65,81,101,183],"mean":[66,152],"baseline":[67],"HbA1c":[68,82],"8.6%,":[70],"those":[72],"RT-CGM":[75,117,125,160,197],"arm":[76,118],"reduction":[83],"1.0%":[85],"compared":[86,143],"0.4%":[88],"SMBG":[91,145,203],"arm.":[92],"A":[93],"quality":[94],"life":[96,135,140],"(QoL)":[97],"benefit":[98,218],"associated":[99,128,219],"reduced":[102,221],"fear":[103],"hypoglycemia":[105],"(FoH)":[106],"elimination":[108,224],"requirement":[111,227],"for":[112,204,228],"fingerstick":[113,229],"testing":[114],"also":[120],"applied.":[121],"RESULTS:":[122],"an":[130,168],"incremental":[131,169],"gain":[132],"quality-adjusted":[134,139],"expectancy":[136],"1.38":[138],"years":[141],"(QALYs)":[142],"(10.64":[146],"QALYs":[147],"9.23":[149],"QALYs).":[150],"Total":[151],"lifetime":[153],"costs":[154],"21,087":[156],"euros":[157,162,174,188],"higher":[158],"(148,077":[161],"126,990":[164],"euros),":[165],"resulting":[166],"ratio":[171],"15,285":[173],"per":[175,189],"QALY":[176,190],"gained.":[177],"CONCLUSIONS:":[178],"In":[179],"France,":[180],"based":[181],"on":[182],"willingness-to-pay":[184],"threshold":[185],"50,000":[187],"gained,":[191],"use":[193],"is":[199],"cost-effective":[200],"relative":[201],"long-standing":[207],"T1D,":[208],"driven":[209],"primarily":[210],"by":[211],"improved":[212],"glycemic":[213],"control":[214],"QoL":[217],"FoH":[222],"testing.":[230]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-11-23T00:00:00"}