{"id":"https://openalex.org/W3101475338","doi":null,"title":"\u0410\u043d\u0430\u043b\u0438\u0437 \u0430\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u0438 \u043f\u043e\u043b\u0438\u043c\u043e\u0440\u0444\u043d\u044b\u0445 \u043b\u043e\u043a\u0443\u0441\u043e\u0432, \u0440\u0430\u0441\u043f\u043e\u043b\u043e\u0436\u0435\u043d\u043d\u044b\u0445 \u0432 \u0441\u0430\u0439\u0442\u0430\u0445 \u0441\u0432\u044f\u0437\u044b\u0432\u0430\u043d\u0438\u044f \u043c\u0438\u043a\u0440\u043e\u0420\u041d\u041a, \u0441 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0435\u043c \u0440\u0430\u043a\u0430 \u043c\u043e\u043b\u043e\u0447\u043d\u043e\u0439 \u0436\u0435\u043b\u0435\u0437\u044b","display_name":"\u0410\u043d\u0430\u043b\u0438\u0437 \u0430\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u0438 \u043f\u043e\u043b\u0438\u043c\u043e\u0440\u0444\u043d\u044b\u0445 \u043b\u043e\u043a\u0443\u0441\u043e\u0432, \u0440\u0430\u0441\u043f\u043e\u043b\u043e\u0436\u0435\u043d\u043d\u044b\u0445 \u0432 \u0441\u0430\u0439\u0442\u0430\u0445 \u0441\u0432\u044f\u0437\u044b\u0432\u0430\u043d\u0438\u044f \u043c\u0438\u043a\u0440\u043e\u0420\u041d\u041a, \u0441 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0435\u043c \u0440\u0430\u043a\u0430 \u043c\u043e\u043b\u043e\u0447\u043d\u043e\u0439 \u0436\u0435\u043b\u0435\u0437\u044b","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3101475338","mag":"3101475338"},"language":"ru","primary_location":{"id":"mag:3101475338","doi":null,"is_oa":false,"landing_page_url":"https://www.medgen-journal.ru/jour/article/view/1382","pdf_url":null,"source":{"id":"https://openalex.org/S4210224986","display_name":"Nauchno-prakticheskii zhurnal \u00abMedicinskaia genetika\u00bb","issn_l":"2073-7998","issn":["2073-7998"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430\u044f \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002916505","display_name":"Marina Bermisheva","orcid":"https://orcid.org/0000-0002-0584-3969","observed_orcids":["https://orcid.org/0000-0002-0584-3969"]},"institutions":[{"id":"https://openalex.org/I172901346","display_name":"St Petersburg University","ror":"https://ror.org/023znxa73","country_code":"RU","type":"education","lineage":["https://openalex.org/I172901346"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Marina Bermisheva","raw_affiliation_strings":["\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-0584-3969","affiliations":[{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb","institution_ids":["https://openalex.org/I172901346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078575489","display_name":"\u0418. \u0420. \u0413\u0438\u043b\u044f\u0437\u043e\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I172901346","display_name":"St Petersburg University","ror":"https://ror.org/023znxa73","country_code":"RU","type":"education","lineage":["https://openalex.org/I172901346"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"\u0418. \u0420. \u0413\u0438\u043b\u044f\u0437\u043e\u0432\u0430","raw_affiliation_strings":["\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb","institution_ids":["https://openalex.org/I172901346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004547350","display_name":"Guzel Zinnatullina","orcid":"https://orcid.org/0000-0001-8369-3399","observed_orcids":["https://orcid.org/0000-0001-8369-3399"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guzel Zinnatullina","raw_affiliation_strings":["\u0413\u0410\u0423\u0417 \u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0430\u043d\u0441\u043a\u0438\u0439 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0434\u0438\u0441\u043f\u0430\u043d\u0441\u0435\u0440 \u041c\u0438\u043d\u0438\u0441\u0442\u0435\u0440\u0441\u0442\u0432\u0430 \u0437\u0434\u0440\u0430\u0432\u043e\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u044f \u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0438 \u0411\u0430\u0448\u043a\u043e\u0440\u0442\u043e\u0441\u0442\u0430\u043d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u0413\u0410\u0423\u0417 \u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0430\u043d\u0441\u043a\u0438\u0439 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043e\u043d\u043a\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0434\u0438\u0441\u043f\u0430\u043d\u0441\u0435\u0440 \u041c\u0438\u043d\u0438\u0441\u0442\u0435\u0440\u0441\u0442\u0432\u0430 \u0437\u0434\u0440\u0430\u0432\u043e\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u044f \u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0438 \u0411\u0430\u0448\u043a\u043e\u0440\u0442\u043e\u0441\u0442\u0430\u043d","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"\u0410. \u0410. \u0411\u043e\u0433\u0434\u0430\u043d\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0001-5509-8023","observed_orcids":["https://orcid.org/0000-0001-5509-8023"]},"institutions":[{"id":"https://openalex.org/I138958963","display_name":"Bashkir State University","ror":"https://ror.org/04gr31p94","country_code":"RU","type":"education","lineage":["https://openalex.org/I138958963","https://openalex.org/I4387155162"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"\u0410. \u0410. \u0411\u043e\u0433\u0434\u0430\u043d\u043e\u0432\u0430","raw_affiliation_strings":["\u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0411\u0430\u0448\u043a\u0438\u0440\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-5509-8023","affiliations":[{"raw_affiliation_string":"\u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0411\u0430\u0448\u043a\u0438\u0440\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb","institution_ids":["https://openalex.org/I138958963"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058282202","display_name":"\u042d. \u041a. \u0425\u0443\u0441\u043d\u0443\u0442\u0434\u0438\u043d\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0003-2987-3334","observed_orcids":["https://orcid.org/0000-0003-2987-3334","https://orcid.org/0000-0002-3438-6007"]},"institutions":[{"id":"https://openalex.org/I172901346","display_name":"St Petersburg University","ror":"https://ror.org/023znxa73","country_code":"RU","type":"education","lineage":["https://openalex.org/I172901346"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"\u042d. \u041a. \u0425\u0443\u0441\u043d\u0443\u0442\u0434\u0438\u043d\u043e\u0432\u0430","raw_affiliation_strings":["\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb"],"raw_orcid":"https://orcid.org/0000-0003-2987-3334","affiliations":[{"raw_affiliation_string":"\u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438 \u0438 \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0438 - \u043e\u0431\u043e\u0441\u043e\u0431\u043b\u0435\u043d\u043d\u043e\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u043d\u043e\u0435 \u043f\u043e\u0434\u0440\u0430\u0437\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0424\u0411\u041d\u0423 \u0423\u0444\u0438\u043c\u0441\u043a\u043e\u0433\u043e \u0444\u0435\u0434\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u043e\u0433\u043e \u0446\u0435\u043d\u0442\u0440\u0430 \u0420\u043e\u0441\u0441\u0438\u0439\u0441\u043a\u043e\u0439 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0438 \u043d\u0430\u0443\u043a; \u0424\u0413\u0411\u041e\u0423 \u0412\u041e \u00ab\u0421\u0430\u043d\u043a\u0442-\u041f\u0435\u0442\u0435\u0440\u0431\u0443\u0440\u0433\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u00bb","institution_ids":["https://openalex.org/I172901346"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11579024,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"6","first_page":"12","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.3400999903678894,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.10100000351667404,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9810000061988831},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9580000042915344},{"id":"https://openalex.org/keywords/microrna-binding-sites","display_name":"microRNA binding sites","score":0.8330000042915344},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7120000123977661},{"id":"https://openalex.org/keywords/erbb4","display_name":"ErbB4","score":0.6759999990463257},{"id":"https://openalex.org/keywords/rad51","display_name":"RAD51","score":0.9890000224113464},{"id":"https://openalex.org/keywords/brca1","display_name":"BRCA1","score":0.9660000205039978},{"id":"https://openalex.org/keywords/brca2","display_name":"BRCA2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/brip1","display_name":"BRIP1","score":0.9160000085830688},{"id":"https://openalex.org/keywords/rad52","display_name":"RAD52","score":0.9490000009536743},{"id":"https://openalex.org/keywords/mre11a","display_name":"MRE11A","score":0.9980000257492065},{"id":"https://openalex.org/keywords/niobium-nitride","display_name":"niobium nitride","score":0.9089999794960022},{"id":"https://openalex.org/keywords/pten","display_name":"PTEN","score":0.9559999704360962},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.7081550359725952},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6589226722717285},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5920510292053223},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5513210892677307},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5423319339752197},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4909384548664093},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.487528532743454},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42849239706993103},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32661178708076477},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12708985805511475},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.06992387771606445},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3101475338","doi":null,"is_oa":false,"landing_page_url":"https://www.medgen-journal.ru/jour/article/view/1382","pdf_url":null,"source":{"id":"https://openalex.org/S4210224986","display_name":"Nauchno-prakticheskii zhurnal \u00abMedicinskaia genetika\u00bb","issn_l":"2073-7998","issn":["2073-7998"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430\u044f \u0433\u0435\u043d\u0435\u0442\u0438\u043a\u0430","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3109416285","https://openalex.org/W2063408296","https://openalex.org/W2767053650","https://openalex.org/W911194015","https://openalex.org/W2767586364","https://openalex.org/W2782459054","https://openalex.org/W1993990674","https://openalex.org/W2109029126","https://openalex.org/W3196599705","https://openalex.org/W2804200911"],"abstract_inverted_index":{"Breast":[0],"cancer":[1,141],"(BC)":[2],"is":[3,75],"a":[4,66],"complex,":[5],"genetically":[6],"heterogeneous":[7],"disease.":[8],"The":[9,72,120],"results":[10,121],"of":[11,19,40,59,81,92,105,122],"numerous":[12],"studies":[13],"have":[14,61],"proven":[15],"the":[16,37,43,57,79,90,123],"important":[17],"role":[18,68],"miRNA":[20,24,41,54],"in":[21,31,42,69,83],"tumor":[22],"progression.":[23],"sequences":[25,33],"are":[26,46,137],"highly":[27],"conserved.":[28],"Any":[29],"variants":[30,104,129],"these":[32],"as":[34,36,86,116],"well":[35],"binding":[38],"sites":[39,85],"target":[44],"genes":[45,60,115],"supposed":[47],"to":[48,64,101],"be":[49],"under":[50],"negative":[51],"selective":[52],"pressure.":[53],"that":[55,127],"alter":[56],"expression":[58],"been":[62],"identified":[63],"play":[65],"significant":[67],"BC":[70,117],"regulation.":[71],"present":[73,124],"study":[74,98,125],"aimed":[76],"at":[77],"investigating":[78],"involvement":[80],"SNPs":[82],"miRNA-binding":[84],"risk":[87,118],"factors":[88],"for":[89],"development":[91],"BC.":[93],"A":[94],"case":[95],"-":[96],"control":[97],"was":[99],"performed":[100],"evaluate":[102],"genetic":[103,128],"BRCA1,":[106],"BRCA2,":[107],"BRIP1,":[108],"RAD51,":[109],"RAD52,":[110],"MRE11A,":[111],"NBN,":[112],"ERBB4,":[113],"PTEN":[114],"factors.":[119],"suggest":[126],"rs11895168":[130],"/":[131,135],"ERBB4":[132],"and":[133],"rs7180135":[134],"RAD51":[136],"associated":[138],"with":[139],"breast":[140],"risk.":[142]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-11-23T00:00:00"}