{"id":"https://openalex.org/W3098690344","doi":"https://doi.org/10.1371/journal.pone.0241782","title":"The bio-sonographic index. A novel modality for early detection of acute kidney injury after complex vascular surgery. A protocol for an exploratory prospective study","display_name":"The bio-sonographic index. A novel modality for early detection of acute kidney injury after complex vascular surgery. A protocol for an exploratory prospective study","publication_year":2020,"publication_date":"2020-11-17","ids":{"openalex":"https://openalex.org/W3098690344","doi":"https://doi.org/10.1371/journal.pone.0241782","mag":"3098690344","pmid":"https://pubmed.ncbi.nlm.nih.gov/33201924","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7671487"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0241782","doi":"https://doi.org/10.1371/journal.pone.0241782","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0241782","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0241782&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0241782&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102812920","display_name":"Ahmed Zaky","orcid":"https://orcid.org/0000-0002-0548-6906","observed_orcids":["https://orcid.org/0000-0002-0548-6906"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ahmed Zaky","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":"https://orcid.org/0000-0002-0548-6906","affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043383232","display_name":"Adam W. Beck","orcid":"https://orcid.org/0000-0002-5474-3833","observed_orcids":["https://orcid.org/0000-0002-5474-3833"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam W. Beck","raw_affiliation_strings":["Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100608570","display_name":"Sejong Bae","orcid":"https://orcid.org/0000-0001-9982-3223","observed_orcids":["https://orcid.org/0000-0001-9982-3223"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sejong Bae","raw_affiliation_strings":["Department of Medicine, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031255438","display_name":"Adam B. Sturdivant","orcid":"https://orcid.org/0000-0003-2027-1898","observed_orcids":["https://orcid.org/0000-0003-2027-1898"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Sturdivant","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021946883","display_name":"Amandiy Liwo","orcid":"https://orcid.org/0000-0003-1906-5392","observed_orcids":["https://orcid.org/0000-0003-1906-5392"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amandiy Liwo","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":"https://orcid.org/0000-0003-1906-5392","affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Novak Zdenek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Novak Zdenek","raw_affiliation_strings":["Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081420334","display_name":"Nicole McAnally","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole McAnally","raw_affiliation_strings":["Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032396693","display_name":"Shama Ahmad","orcid":"https://orcid.org/0000-0003-1049-5054","observed_orcids":["https://orcid.org/0000-0003-1049-5054"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shama Ahmad","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063438836","display_name":"J. Brad Meers","orcid":"https://orcid.org/0000-0002-8207-6046","observed_orcids":["https://orcid.org/0000-0002-8207-6046"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad Meers","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032215984","display_name":"Michelle L. Robbin","orcid":"https://orcid.org/0000-0003-4456-5081","observed_orcids":["https://orcid.org/0000-0003-4456-5081"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Robbin","raw_affiliation_strings":["Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067982688","display_name":"Jean\u2010Fran\u00e7ois Pittet","orcid":"https://orcid.org/0000-0002-2196-9289","observed_orcids":["https://orcid.org/0000-0002-2196-9289"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. F. Pittet","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058568676","display_name":"Ashita Tolwani","orcid":"https://orcid.org/0000-0002-2445-0386","observed_orcids":["https://orcid.org/0000-0002-2445-0386"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashita Tolwani","raw_affiliation_strings":["Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007096980","display_name":"Dan E. Berkowitz","orcid":"https://orcid.org/0000-0003-2232-9416","observed_orcids":["https://orcid.org/0000-0003-2232-9416"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan Berkowitz","raw_affiliation_strings":["Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5102812920"],"corresponding_institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"],"apc_list":{"value":1695,"currency":"USD","value_usd":1695},"apc_paid":{"value":1695,"currency":"USD","value_usd":1695},"fwci":0.1568,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54563452,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"15","issue":"11","first_page":"e0241782","last_page":"e0241782"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.984000027179718},{"id":"https://openalex.org/keywords/shear-wave-elastography","display_name":"shear wave elastography","score":0.9890000224113464},{"id":"https://openalex.org/keywords/renal-ultrasound","display_name":"renal ultrasound","score":0.460999995470047},{"id":"https://openalex.org/keywords/aortic-surgery","display_name":"aortic surgery","score":0.7059999704360962},{"id":"https://openalex.org/keywords/endovascular-aortic-repair","display_name":"endovascular aortic repair","score":0.8059999942779541},{"id":"https://openalex.org/keywords/igfbp7","display_name":"IGFBP7","score":0.8360000252723694},{"id":"https://openalex.org/keywords/timp-2","display_name":"TIMP-2","score":0.9890000224113464},{"id":"https://openalex.org/keywords/neutrophil-gelatinase-associated-lipocalin","display_name":"neutrophil gelatinase-associated lipocalin","score":0.9739999771118164},{"id":"https://openalex.org/keywords/kdigo-criteria","display_name":"KDIGO criteria","score":0.6499999761581421},{"id":"https://openalex.org/keywords/renal-biomarkers","display_name":"renal biomarkers","score":0.5870000123977661},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8632524013519287},{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.7363986968994141},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5368161201477051},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.515975296497345},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.49704888463020325},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.4787958562374115},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.45453080534935},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4406333267688751},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4253317713737488},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3916390538215637},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.35140496492385864},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000071068","descriptor_name":"Lipocalin-2","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D018969","descriptor_name":"Insulin-Like Growth Factor Binding Proteins","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D019716","descriptor_name":"Tissue Inhibitor of Metalloproteinase-2","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D054459","descriptor_name":"Elasticity Imaging Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057510","descriptor_name":"Endovascular Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D059447","descriptor_name":"Cell Cycle Checkpoints","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1371/journal.pone.0241782","doi":"https://doi.org/10.1371/journal.pone.0241782","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0241782","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0241782&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7671487","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7671487","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:33201924","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33201924","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:095da3043cfd4c7382e778b8b1ae2873","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/095da3043cfd4c7382e778b8b1ae2873","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 15, Iss 11, p e0241782 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0241782","doi":"https://doi.org/10.1371/journal.pone.0241782","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0241782","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0241782&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/study-protocol","display_name":"Study Protocol"}],"awards":[{"id":"https://openalex.org/G5094150098","display_name":null,"funder_award_id":"3122053.000.213122053.311850000.0000","funder_id":"https://openalex.org/F4320312852","funder_display_name":"University of Alabama"}],"funders":[{"id":"https://openalex.org/F4320310431","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205"},{"id":"https://openalex.org/F4320312852","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3098690344.pdf","grobid_xml":"https://content.openalex.org/works/W3098690344.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1942447387","https://openalex.org/W1989043420","https://openalex.org/W1994837852","https://openalex.org/W2003500862","https://openalex.org/W2006617902","https://openalex.org/W2016965599","https://openalex.org/W2032368204","https://openalex.org/W2045272170","https://openalex.org/W2071942150","https://openalex.org/W2103205889","https://openalex.org/W2131419242","https://openalex.org/W2148152947","https://openalex.org/W2148903912","https://openalex.org/W2155982020","https://openalex.org/W2160274305","https://openalex.org/W2167831643","https://openalex.org/W2168729190","https://openalex.org/W2169504018","https://openalex.org/W2204446205","https://openalex.org/W2336900399","https://openalex.org/W2531369030","https://openalex.org/W2547465391","https://openalex.org/W2565010837","https://openalex.org/W2604454724","https://openalex.org/W2610992277","https://openalex.org/W2743418501","https://openalex.org/W2745062606","https://openalex.org/W2745803317","https://openalex.org/W2752268598","https://openalex.org/W2808259566","https://openalex.org/W2810817334","https://openalex.org/W2913317505","https://openalex.org/W2980567378","https://openalex.org/W2980801506","https://openalex.org/W2989615501","https://openalex.org/W2994856154","https://openalex.org/W3133528108"],"related_works":["https://openalex.org/W4400302998","https://openalex.org/W3118302893","https://openalex.org/W4377115426","https://openalex.org/W2890412750","https://openalex.org/W3203321141","https://openalex.org/W6990597040","https://openalex.org/W4383669876","https://openalex.org/W21799193","https://openalex.org/W2803771684","https://openalex.org/W3021464749"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Acute":[1],"kidney":[2],"injury":[3,108],"(AKI)":[4],"is":[5,54,164],"a":[6,57,80,125,293],"common":[7],"complication":[8],"of":[9,24,32,51,59,62,73,84,90,102,141,167,189,205,221,224,235,253,256,269,296,306],"complex":[10,313],"aortic":[11],"surgery":[12],"with":[13,39],"high":[14],"mortality,":[15],"morbidity":[16],"and":[17,35,46,69,100,106,138,152,155,206,232,238,248,266,271,302],"health":[18],"care":[19],"expense.":[20],"The":[21,49,145,161,213],"current":[22],"definition":[23],"AKI":[25,74,168,270,307],"does":[26],"not":[27,195],"allow":[28],"for":[29,218],"structural":[30,63,298],"characterization":[31],"the":[33,71,115,142,159,165,171,203,209,222,236,243,257,264,283,289,304],"kidneys":[34],"utilizes":[36],"functional":[37],"indices":[38,268],"substantial":[40],"limitations":[41],"leading":[42],"to":[43,55,170,201,207,277],"delayed":[44],"diagnosis":[45],"ineffective":[47],"interventions.":[48],"aim":[50],"this":[52,76],"study":[53,123],"develop":[56],"method":[58],"early":[60,297],"detection":[61],"renal":[64,91,107],"abnormalities":[65,299],"that":[66,288,300],"can":[67],"precede":[68,301],"predict":[70,303],"occurrence":[72,166,223,305],"in":[75,242,251,312],"population.":[77],"We":[78,286],"propose":[79],"novel":[81,210],"combined":[82,233],"index":[83,117,295],"ultrasonography":[85],"(shear":[86],"wave":[87],"elastography),":[88],"biomarkers":[89],"stress":[92],"(urinary":[93,110],"insulin":[94],"growth":[95],"factor":[96],"binding":[97],"protein-7,":[98],"IGFBP-7":[99],"inhibitor":[101],"tissue":[103],"metalloproteinase-2,":[104],"TIMP-2)":[105],"markers":[109,240],"neutrophil":[111],"gelatinase-associated":[112],"lipocalin":[113],"-NGAL)-":[114],"bio-sonographic":[116],"(BSI).":[118],"METHODS:":[119],"A":[120,186],"prospective":[121],"observational":[122],"at":[124,150,153],"tertiary":[126],"referral":[127],"center":[128],"will":[129,147,181,198,215,227,260,274,291],"be":[130,148,182,199,216,228,261,275,292],"performed":[131],"enrolling":[132],"80":[133],"patients":[134],"undergoing":[135,196],"elective":[136],"open":[137],"endovascular":[139],"repair":[140],"visceral":[143],"aorta.":[144],"BSI":[146,214,237,265,290],"evaluated":[149],"baseline,":[151],"6":[154],"24":[156],"hours":[157],"after":[158],"procedure.":[160],"primary":[162],"outcome":[163],"according":[169],"Kidney":[172],"Disease":[173],"Improving":[174],"Global":[175],"Outcomes":[176],"(KDIGO)":[177],"criteria.":[178],"Each":[179],"patient":[180],"his/her":[183],"own":[184],"control.":[185],"reference":[187],"group":[188],"15":[190],"healthy":[191],"volunteers":[192],"who":[193],"are":[194],"interventions":[197],"enrolled":[200],"test":[202],"feasibility":[204],"refine":[208],"SWE":[211],"protocol.":[212],"tested":[217],"its":[219],"predictability":[220],"AKI.":[225],"Comparisons":[226],"made":[229,262],"between":[230,263],"individual":[231,279],"components":[234],"traditional":[239],"used":[241],"KDIGO":[244,311],"definition;":[245],"serum":[246],"creatinine":[247],"urine":[249],"output":[250],"terms":[252],"baseline":[254],"status":[255],"kidney.":[258],"Correlations":[259],"conventional":[267],"exploratory":[272],"analyses":[273],"conducted":[276],"identify":[278],"disease":[280],"patterns":[281],"using":[282],"BSI.":[284],"DISCUSSION:":[285],"hypothesize":[287],"sensitive":[294],"as":[308],"defined":[309],"by":[310],"vascular":[314],"surgery.":[315],"TRIAL":[316],"REGISTRATION:":[317],"ClinicalTrials.gov":[318],"NCT04144894.":[319],"Registered":[320],"1/6/2020.":[321]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-11-23T00:00:00"}