{"id":"https://openalex.org/W3097274675","doi":"https://doi.org/10.1530/ey.17.7.13","title":"Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan","display_name":"Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan","publication_year":2020,"publication_date":"2020-10-23","ids":{"openalex":"https://openalex.org/W3097274675","doi":"https://doi.org/10.1530/ey.17.7.13","mag":"3097274675"},"language":"en","primary_location":{"id":"doi:10.1530/ey.17.7.13","doi":"https://doi.org/10.1530/ey.17.7.13","is_oa":false,"landing_page_url":"https://doi.org/10.1530/ey.17.7.13","pdf_url":null,"source":{"id":"https://openalex.org/S4210193404","display_name":"Yearbook of pediatric endocrinology","issn_l":"1662-3991","issn":["1662-3991","1662-4009"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yearbook of Paediatric Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.utupub.fi/bitstreams/c6584707-349d-4000-a562-44bd7cfa6e26/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085607563","display_name":"Brian Hollis","orcid":"https://orcid.org/0000-0002-1726-2539","observed_orcids":["https://orcid.org/0000-0002-1726-2539"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hollis B","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010213549","display_name":"Day FR","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Day FR","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056538875","display_name":"Busch AS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Busch AS","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Thompson DJ","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thompson DJ","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025035399","display_name":"Soares ALG","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soares ALG","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049427972","display_name":"Timmers PRHJ","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timmers PRHJ","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063576136","display_name":"Alex S. F. Kwong","orcid":"https://orcid.org/0000-0003-1953-2771","observed_orcids":["https://orcid.org/0000-0003-1953-2771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kwong A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057956538","display_name":"Easton Df","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Easton DF","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103697850","display_name":"Joshi Pk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joshi PK","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014467923","display_name":"Ken K. Ong","orcid":"https://orcid.org/0000-0003-4689-7530","observed_orcids":["https://orcid.org/0000-0003-4689-7530","https://orcid.org/0000-0001-7410-7992"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ong KK","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5027806970","display_name":"John R. B. Perry","orcid":"https://orcid.org/0000-0001-6483-3771","observed_orcids":["https://orcid.org/0000-0001-6483-3771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Perry JRB","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18307077,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.020899999886751175,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pubertal-timing","display_name":"pubertal timing","score":0.6320000290870667},{"id":"https://openalex.org/keywords/hair-color","display_name":"hair color","score":0.8130000233650208},{"id":"https://openalex.org/keywords/lifespan","display_name":"lifespan","score":0.9190000295639038},{"id":"https://openalex.org/keywords/genomic-correlation","display_name":"genomic correlation","score":0.6949999928474426},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7210000157356262},{"id":"https://openalex.org/keywords/pituitary-hormones","display_name":"pituitary hormones","score":0.8679999709129333},{"id":"https://openalex.org/keywords/pigmentation","display_name":"pigmentation","score":0.7350000143051147},{"id":"https://openalex.org/keywords/mendelian-randomization","display_name":"Mendelian randomization","score":0.925000011920929},{"id":"https://openalex.org/keywords/health-outcomes","display_name":"health outcomes","score":0.6470000147819519},{"id":"https://openalex.org/keywords/susceptibility-loci","display_name":"genetic susceptibility loci","score":0.45399999618530273}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6258602142333984},{"id":"https://openalex.org/C3020618081","wikidata":"https://www.wikidata.org/wiki/Q5937811","display_name":"Hair growth","level":2,"score":0.5614446997642517},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.488486647605896},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3542611598968506},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.34264951944351196}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1530/ey.17.7.13","doi":"https://doi.org/10.1530/ey.17.7.13","is_oa":false,"landing_page_url":"https://doi.org/10.1530/ey.17.7.13","pdf_url":null,"source":{"id":"https://openalex.org/S4210193404","display_name":"Yearbook of pediatric endocrinology","issn_l":"1662-3991","issn":["1662-3991","1662-4009"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yearbook of Paediatric Endocrinology","raw_type":"journal-article"},{"id":"pmh:oai:utupub.fi:11111/29493","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/29493","pdf_url":"https://www.utupub.fi/bitstreams/c6584707-349d-4000-a562-44bd7cfa6e26/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/154958","raw_type":null},{"id":"pmh:oai:www.utupub.fi:10024/154958","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/10024/154958","pdf_url":"https://www.utupub.fi/bitstream/10024/154958/1/s41467-020-14451-5.pdf","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utupub.fi:11111/29493","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/29493","pdf_url":"https://www.utupub.fi/bitstreams/c6584707-349d-4000-a562-44bd7cfa6e26/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/154958","raw_type":null},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1136991791","display_name":null,"funder_award_id":"A10692","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1161123863","display_name":null,"funder_award_id":"223175","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1192034430","display_name":null,"funder_award_id":"102215","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G1284471813","display_name":"Imputation-based approach to identify low frequency variants in prostate cancer","funder_award_id":"U01CA188392","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1307361660","display_name":null,"funder_award_id":"A7357","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1516858932","display_name":null,"funder_award_id":"C5047/A10692","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1605161196","display_name":null,"funder_award_id":"102215/2/13/2)","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G1767914659","display_name":null,"funder_award_id":"HEALTH-F2-2009-223175","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G188264227","display_name":null,"funder_award_id":"C5047/A7357","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G1891520518","display_name":null,"funder_award_id":"A3354","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G2158889896","display_name":null,"funder_award_id":"102215/2/13/2","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G236237718","display_name":null,"funder_award_id":"C1287\u2010A10118","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G2453522775","display_name":null,"funder_award_id":"HEALTHF2-2009-223175","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G2694076841","display_name":null,"funder_award_id":"HEALTH-F2-2009-223175","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2734198957","display_name":null,"funder_award_id":"C5047/A3354","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G2892497062","display_name":null,"funder_award_id":"MC_UU_12015","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2953759644","display_name":null,"funder_award_id":"A10118","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G3831911591","display_name":null,"funder_award_id":"102215/2/13/2","funder_id":"https://openalex.org/F4320320360","funder_display_name":"University of Bristol"},{"id":"https://openalex.org/G4098640521","display_name":null,"funder_award_id":"HEALTH-F2-2009-223175","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4167275758","display_name":null,"funder_award_id":"\u2018C5047/A10692","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4197410787","display_name":null,"funder_award_id":"C1287","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G4467937127","display_name":"The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019.","funder_award_id":"102215","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4662672464","display_name":null,"funder_award_id":"C1287/A10118","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G5347321386","display_name":null,"funder_award_id":"A6135","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G5562631338","display_name":null,"funder_award_id":"102215/2/13/2","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5585565996","display_name":null,"funder_award_id":"C1287/A16563","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5712372172","display_name":null,"funder_award_id":"HHSN268201200008I","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6294906247","display_name":null,"funder_award_id":"C5047/A10692","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6301433572","display_name":null,"funder_award_id":"C5047","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6858204494","display_name":null,"funder_award_id":"C5047/A10692","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G6862617662","display_name":null,"funder_award_id":"HHSN268201200008I","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7223051280","display_name":null,"funder_award_id":"C1287/A16563","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7238546996","display_name":null,"funder_award_id":"C1287/A16563","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7242219286","display_name":null,"funder_award_id":"C1287/A10118","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G728243498","display_name":null,"funder_award_id":"C16913-A6135","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G7383316951","display_name":null,"funder_award_id":"C1287/A10118","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7501896692","display_name":null,"funder_award_id":"A16563","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G7879942274","display_name":null,"funder_award_id":"CA 148537-01","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7973277461","display_name":null,"funder_award_id":"X01HG007492","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8760561684","display_name":"Child Growth and development","funder_award_id":"MC_UU_12015/2","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G880611044","display_name":null,"funder_award_id":"C1287\u2010A16563","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"}],"funders":[{"id":"https://openalex.org/F4320310702","display_name":"National Cancer Research Institute","ror":"https://ror.org/02mp0vf47"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313309","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320360","display_name":"University of Bristol","ror":"https://ror.org/0524sp257"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3097274675.pdf","grobid_xml":"https://content.openalex.org/works/W3097274675.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6925377334","https://openalex.org/W2765668780","https://openalex.org/W2192383868","https://openalex.org/W3018341844","https://openalex.org/W2282434646","https://openalex.org/W4406515551","https://openalex.org/W2944189406","https://openalex.org/W1895171560","https://openalex.org/W579022887","https://openalex.org/W2527298399"],"abstract_inverted_index":{"The":[0],"timing":[1,23,42,59,82,101,121,132,145],"of":[2,17,21,48,91,140,143],"puberty":[3,22,41,58,72,81,95,100,120,131,144],"is":[4,8,24,102],"highly":[5],"variable":[6],"and":[7,65,83,96,110,122,133,136],"associated":[9],"with":[10,43,105],"long-term":[11],"health":[12,108,134],"outcomes.":[13],"To":[14],"date,":[15],"understanding":[16],"the":[18,128,138],"genetic":[19,116,141],"control":[20],"based":[25],"largely":[26],"on":[27,94],"studies":[28,142],"in":[29,57,146],"women.":[30],"Here,":[31],"we":[32],"report":[33],"a":[34,115],"multi-trait":[35],"genome-wide":[36],"association":[37,117],"study":[38],"for":[39,70],"male":[40,71,99,119],"an":[44,77],"effective":[45],"sample":[46],"size":[47],"205,354":[49],"men.":[50],"We":[51],"find":[52],"moderately":[53],"strong":[54],"genomic":[55],"correlation":[56],"between":[60,80,118,130],"sexes":[61],"(rg":[62],"=":[63],"0.68)":[64],"identify":[66],"76":[67],"independent":[68],"signals":[69],"timing.":[73],"Implicated":[74],"mechanisms":[75],"include":[76],"unexpected":[78],"link":[79],"natural":[84],"hair":[85],"colour,":[86],"possibly":[87],"reflecting":[88],"common":[89],"effects":[90],"pituitary":[92],"hormones":[93],"pigmentation.":[97],"Earlier":[98],"genetically":[103],"correlated":[104],"several":[106],"adverse":[107],"outcomes":[109],"Mendelian":[111],"randomization":[112],"analyses":[113],"show":[114],"shorter":[123],"lifespan.":[124],"These":[125],"findings":[126],"highlight":[127],"relationships":[129],"outcomes,":[135],"demonstrate":[137],"value":[139],"both":[147],"sexes.":[148]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-11-09T00:00:00"}