{"id":"https://openalex.org/W3096185094","doi":null,"title":"Case Study: Rapid Complete Recovery From An Autism Spectrum Disorder After Treatment of Aspergillus With The Antifungal Drugs Itraconazole And Sporanox.","display_name":"Case Study: Rapid Complete Recovery From An Autism Spectrum Disorder After Treatment of Aspergillus With The Antifungal Drugs Itraconazole And Sporanox.","publication_year":2020,"publication_date":"2020-08-01","ids":{"openalex":"https://openalex.org/W3096185094","mag":"3096185094","pmid":"https://pubmed.ncbi.nlm.nih.gov/33132781","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7572136"},"language":"en","primary_location":{"id":"pmid:33132781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33132781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Integrative medicine (Encinitas, Calif.)","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7572136/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050433009","display_name":"Sidney MacDonald Baker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sidney Baker","raw_affiliation_strings":["Private practice in Sag Harbor, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Private practice in Sag Harbor, New York","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"William Shaw","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William Shaw","raw_affiliation_strings":["The Great Plains Laboratory in Lenexa, Kansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Great Plains Laboratory in Lenexa, Kansas","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5937,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.58612121,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"19","issue":"4","first_page":"20","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.4187000095844269,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.2410999983549118,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.21660000085830688,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aspergillus","display_name":"Aspergillus","score":0.9580000042915344},{"id":"https://openalex.org/keywords/itraconazole","display_name":"itraconazole","score":0.8930000066757202},{"id":"https://openalex.org/keywords/antifungal-therapy","display_name":"antifungal therapy","score":0.7070000171661377},{"id":"https://openalex.org/keywords/herxheimer-reaction","display_name":"Herxheimer reaction","score":0.9629999995231628},{"id":"https://openalex.org/keywords/pediatric-patients","display_name":"pediatric patients","score":0.38199999928474426},{"id":"https://openalex.org/keywords/liver-function-monitoring","display_name":"liver function monitoring","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C2777071850","wikidata":"https://www.wikidata.org/wiki/Q411229","display_name":"Itraconazole","level":3,"score":0.9272737503051758},{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.6883822679519653},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.67329341173172},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5712020993232727},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.49956202507019043},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3820973336696625},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.33823785185813904},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.287775456905365},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.24558362364768982}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:33132781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33132781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Integrative medicine (Encinitas, Calif.)","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:7572136","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7572136/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Integr Med (Encinitas)","raw_type":"Text"},{"id":"mag:3096185094","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33132781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7572136","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7572136/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Integr Med (Encinitas)","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W151390786","https://openalex.org/W2013750847","https://openalex.org/W2017417207","https://openalex.org/W2054761095","https://openalex.org/W2101888910","https://openalex.org/W2114436773","https://openalex.org/W2126027573","https://openalex.org/W2132957742","https://openalex.org/W2466642275","https://openalex.org/W2794632074","https://openalex.org/W2973932023"],"related_works":["https://openalex.org/W2027432897","https://openalex.org/W3163666691","https://openalex.org/W1999065155","https://openalex.org/W2410666238","https://openalex.org/W2364737202","https://openalex.org/W2062632151","https://openalex.org/W2163833410","https://openalex.org/W1981350886","https://openalex.org/W3011275172","https://openalex.org/W1974768154"],"abstract_inverted_index":{"CONTEXT:":[0],"A":[1,47],"dramatic":[2],"Herxheimer":[3],"reaction":[4],"provided":[5],"strong":[6],"clinical":[7],"indications":[8],"that":[9],"mold":[10],"colonization":[11],"might":[12],"be":[13],"a":[14,83],"factor":[15],"in":[16,19],"causing":[17],"autism":[18,43,51],"this":[20],"child.":[21],"OBJECTIVE:":[22],"species.":[23],"SETTING:":[24],"The":[25,62],"child":[26,40,48,63],"was":[27,64],"treated":[28],"as":[29,82],"an":[30,42,50],"outpatient":[31],"by":[32],"the":[33,39,59,76],"physician":[34],"who":[35],"had":[36],"first":[37],"diagnosed":[38],"with":[41,49,68],"spectrum":[44,52],"disorder.":[45,53],"PARTICIPANT:":[46],"INTERVENTION:":[54],"brand":[55],"of":[56,87],"itraconazole":[57],"gave":[58],"best":[60],"results.":[61],"monitored":[65],"twice":[66],"weekly":[67],"liver":[69],"function":[70],"tests":[71],"which":[72],"remained":[73],"normal":[74],"throughout":[75],"therapy.":[77],"RESULTS:":[78],"colonization.":[79],"CONCLUSIONS:":[80],"specifically":[81],"potential":[84],"major":[85],"cause":[86],"autism.":[88]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-11-09T00:00:00"}