{"id":"https://openalex.org/W3095992491","doi":"https://doi.org/10.1007/s00394-020-02427-6","title":"CYP1A2 genotype and acute ergogenic effects of caffeine intake on exercise performance: a systematic review","display_name":"CYP1A2 genotype and acute ergogenic effects of caffeine intake on exercise performance: a systematic review","publication_year":2020,"publication_date":"2020-11-02","ids":{"openalex":"https://openalex.org/W3095992491","doi":"https://doi.org/10.1007/s00394-020-02427-6","mag":"3095992491","pmid":"https://pubmed.ncbi.nlm.nih.gov/33137206"},"language":"en","primary_location":{"id":"doi:10.1007/s00394-020-02427-6","doi":"https://doi.org/10.1007/s00394-020-02427-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00394-020-02427-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210183135","display_name":"European Journal of Nutrition","issn_l":"1436-6207","issn":["1436-6207","1436-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Nutrition","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059678310","display_name":"Jozo Grgi\u0107","orcid":"https://orcid.org/0000-0002-6929-2844","observed_orcids":["https://orcid.org/0000-0002-6929-2844"]},"institutions":[{"id":"https://openalex.org/I71270174","display_name":"Victoria University","ror":"https://ror.org/04j757h98","country_code":"AU","type":"education","lineage":["https://openalex.org/I71270174"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Jozo Grgic","raw_affiliation_strings":["Institute for Health and Sport (IHES), Victoria University, Melbourne, VIC, Australia. jozo.grgic@live.vu.edu.au","Institute for Health and Sport (IHES), Victoria University, Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Health and Sport (IHES), Victoria University, Melbourne, VIC, Australia. jozo.grgic@live.vu.edu.au","institution_ids":["https://openalex.org/I71270174"]},{"raw_affiliation_string":"Institute for Health and Sport (IHES), Victoria University, Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I71270174"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043595974","display_name":"Craig Pickering","orcid":"https://orcid.org/0000-0002-7056-4966","observed_orcids":["https://orcid.org/0000-0002-7056-4966"]},"institutions":[{"id":"https://openalex.org/I185852735","display_name":"University of Lancashire","ror":"https://ror.org/010jbqd54","country_code":"GB","type":"education","lineage":["https://openalex.org/I185852735"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Craig Pickering","raw_affiliation_strings":["Institute of Coaching and Performance, School of Sport and Wellbeing, University of Central Lancashire, Preston, PR1 2HE, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Coaching and Performance, School of Sport and Wellbeing, University of Central Lancashire, Preston, PR1 2HE, UK","institution_ids":["https://openalex.org/I185852735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004496553","display_name":"Juan Del Coso","orcid":"https://orcid.org/0000-0002-5785-984X","observed_orcids":["https://orcid.org/0000-0002-5785-984X"]},"institutions":[{"id":"https://openalex.org/I182083151","display_name":"Universidad Rey Juan Carlos","ror":"https://ror.org/01v5cv687","country_code":"ES","type":"education","lineage":["https://openalex.org/I182083151"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Del Coso","raw_affiliation_strings":["Centre for Sport Studies, Rey Juan Carlos University, Fuenlabrada, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Sport Studies, Rey Juan Carlos University, Fuenlabrada, Spain","institution_ids":["https://openalex.org/I182083151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001186834","display_name":"Brad Jon Schoenfeld","orcid":"https://orcid.org/0000-0003-4979-5783","observed_orcids":["https://orcid.org/0000-0003-4979-5783"]},"institutions":[{"id":"https://openalex.org/I161301626","display_name":"Lehman College","ror":"https://ror.org/03m908832","country_code":"US","type":"education","lineage":["https://openalex.org/I161301626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad J. Schoenfeld","raw_affiliation_strings":["Department of Health Sciences, Lehman College, Bronx, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Sciences, Lehman College, Bronx, NY, USA","institution_ids":["https://openalex.org/I161301626"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076544743","display_name":"Pavle Mikuli\u0107","orcid":"https://orcid.org/0000-0003-1244-631X","observed_orcids":["https://orcid.org/0000-0003-1244-631X"]},"institutions":[{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Pavle Mikulic","raw_affiliation_strings":["Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5059678310"],"corresponding_institution_ids":["https://openalex.org/I71270174"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":0.6191,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.52175864,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"60","issue":"3","first_page":"1181","last_page":"1195"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13354","display_name":"Genetics and Physical Performance","score":0.010300000198185444,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.8690000176429749},{"id":"https://openalex.org/keywords/ergogenic-aids","display_name":"ergogenic aids","score":0.7400000095367432},{"id":"https://openalex.org/keywords/exercise-performance","display_name":"exercise performance","score":0.7350000143051147},{"id":"https://openalex.org/keywords/genetic-variation","display_name":"genetic variation","score":0.5479999780654907},{"id":"https://openalex.org/keywords/caffeine-metabolism","display_name":"caffeine metabolism","score":0.5429999828338623},{"id":"https://openalex.org/keywords/cardiorespiratory-fitness","display_name":"cardiorespiratory fitness","score":0.8769999742507935},{"id":"https://openalex.org/keywords/high-intensity-exercise","display_name":"high-intensity exercise","score":0.8410000205039978},{"id":"https://openalex.org/keywords/resistance-training","display_name":"resistance training","score":0.8080000281333923},{"id":"https://openalex.org/keywords/cycling-time-trial","display_name":"cycling time trial","score":0.6129999756813049},{"id":"https://openalex.org/keywords/caffeine-supplementation","display_name":"caffeine supplementation","score":0.3889999985694885}],"concepts":[{"id":"https://openalex.org/C2778500429","wikidata":"https://www.wikidata.org/wiki/Q60235","display_name":"Caffeine","level":2,"score":0.8685570955276489},{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.7219042181968689},{"id":"https://openalex.org/C86745063","wikidata":"https://www.wikidata.org/wiki/Q3737406","display_name":"CYP1A2","level":4,"score":0.6899687647819519},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.6134853363037109},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5983155965805054},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.4510962665081024},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.4424534738063812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3843074440956116},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3831394612789154},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18567794561386108},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08683103322982788},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.0},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002110","descriptor_name":"Caffeine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010807","descriptor_name":"Physical Endurance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019388","descriptor_name":"Cytochrome P-450 CYP1A2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D058573","descriptor_name":"Performance-Enhancing Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00394-020-02427-6","doi":"https://doi.org/10.1007/s00394-020-02427-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00394-020-02427-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210183135","display_name":"European Journal of Nutrition","issn_l":"1436-6207","issn":["1436-6207","1436-6215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Nutrition","raw_type":"journal-article"},{"id":"pmid:33137206","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33137206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:clok.uclan.ac.uk:35554","doi":null,"is_oa":false,"landing_page_url":"https://clok.uclan.ac.uk/id/eprint/35554/1/35554%20CYP1A2%20Review.pdf","pdf_url":"https://clok.uclan.ac.uk/id/eprint/35554/1/35554%20CYP1A2%20Review.pdf","source":{"id":"https://openalex.org/S4306402361","display_name":"CLOK (University of Central Lancashire)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185852735","host_organization_name":"University of Lancashire","host_organization_lineage":["https://openalex.org/I185852735"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:eprints.vu.edu.au:42416","doi":null,"is_oa":false,"landing_page_url":"https://vuir.vu.edu.au/42416/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400215","display_name":"Victoria University Research Repository (Victoria University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I41156924","host_organization_name":"Victoria University of Wellington","host_organization_lineage":["https://openalex.org/I41156924"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W71228264","https://openalex.org/W1734451748","https://openalex.org/W1882505253","https://openalex.org/W1928089100","https://openalex.org/W1969577334","https://openalex.org/W1997449456","https://openalex.org/W2021943540","https://openalex.org/W2026010772","https://openalex.org/W2042513662","https://openalex.org/W2054786439","https://openalex.org/W2093654487","https://openalex.org/W2102968146","https://openalex.org/W2103839971","https://openalex.org/W2118402169","https://openalex.org/W2127486867","https://openalex.org/W2130611622","https://openalex.org/W2134833483","https://openalex.org/W2136135441","https://openalex.org/W2145026508","https://openalex.org/W2161465738","https://openalex.org/W2165388012","https://openalex.org/W2165845864","https://openalex.org/W2224962943","https://openalex.org/W2330826434","https://openalex.org/W2408380407","https://openalex.org/W2417998883","https://openalex.org/W2595836811","https://openalex.org/W2620906490","https://openalex.org/W2742183927","https://openalex.org/W2753818182","https://openalex.org/W2778169311","https://openalex.org/W2791163366","https://openalex.org/W2791466980","https://openalex.org/W2792953184","https://openalex.org/W2793021392","https://openalex.org/W2793103700","https://openalex.org/W2797913252","https://openalex.org/W2799385931","https://openalex.org/W2805501279","https://openalex.org/W2843105544","https://openalex.org/W2888519456","https://openalex.org/W2889367161","https://openalex.org/W2910266035","https://openalex.org/W2913413117","https://openalex.org/W2914045481","https://openalex.org/W2930495386","https://openalex.org/W2987853405","https://openalex.org/W2989812467","https://openalex.org/W2991453564","https://openalex.org/W2996999258","https://openalex.org/W3010767403","https://openalex.org/W3013370518","https://openalex.org/W3016793359","https://openalex.org/W3021620141","https://openalex.org/W3035149897","https://openalex.org/W3048418800","https://openalex.org/W4297918764"],"related_works":["https://openalex.org/W6887704700","https://openalex.org/W3120747900","https://openalex.org/W4390349520","https://openalex.org/W4387062147","https://openalex.org/W7171460586","https://openalex.org/W2595836811","https://openalex.org/W2792953184","https://openalex.org/W2130611622","https://openalex.org/W4415313029","https://openalex.org/W7127156499"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-11-09T00:00:00"}