{"id":"https://openalex.org/W3095337639","doi":null,"title":"Anatomically informed image reconstruction for time of flight positron emission tomography","display_name":"Anatomically informed image reconstruction for time of flight positron emission tomography","publication_year":2020,"publication_date":"2020-02-01","ids":{"openalex":"https://openalex.org/W3095337639","mag":"3095337639"},"language":"en","primary_location":{"id":"pmh:oai:etheses.whiterose.ac.uk:27865","doi":null,"is_oa":true,"landing_page_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","pdf_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065782051","display_name":"Palak Wadhwa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Palak Wadhwa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5065782051"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11216","display_name":"Radiation Detection and Scintillator Technologies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/time-of-flight-positron-emission-tomography","display_name":"time-of-flight positron emission tomography","score":0.9480000138282776},{"id":"https://openalex.org/keywords/pet-mr","display_name":"PET/MR","score":0.8429999947547913},{"id":"https://openalex.org/keywords/acquisition-models","display_name":"acquisition models","score":0.7699999809265137},{"id":"https://openalex.org/keywords/pet-quantification","display_name":"PET quantification","score":0.6470000147819519},{"id":"https://openalex.org/keywords/scan-time-reduction","display_name":"scan time reduction","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.7423657178878784},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.6506727933883667},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.619005560874939},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5581533908843994},{"id":"https://openalex.org/C2779751349","wikidata":"https://www.wikidata.org/wiki/Q1474480","display_name":"Scanner","level":2,"score":0.49896740913391113},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.479853093624115},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4643099308013916},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.45463815331459045},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4494476318359375},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4216683506965637},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.42023521661758423},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.40342339873313904},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3297646939754486},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19457262754440308},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.1023106575012207},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etheses.whiterose.ac.uk:27865","doi":null,"is_oa":true,"landing_page_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","pdf_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:3095337639","doi":null,"is_oa":false,"landing_page_url":"https://etheses.whiterose.ac.uk/27865/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.whiterose.ac.uk:27865","doi":null,"is_oa":true,"landing_page_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","pdf_url":"https://etheses.whiterose.ac.uk/27865/1/Wadhwa_P_Medicine_PhD_2020.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320286","display_name":"University College London","ror":"https://ror.org/02jx3x895"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3095337639.pdf","grobid_xml":"https://content.openalex.org/works/W3095337639.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W183351562","https://openalex.org/W320279285","https://openalex.org/W1546274595","https://openalex.org/W1585078554","https://openalex.org/W1647554959","https://openalex.org/W1940721824","https://openalex.org/W1967374611","https://openalex.org/W1978419388","https://openalex.org/W1980311256","https://openalex.org/W1982527613","https://openalex.org/W1987781166","https://openalex.org/W1989936418","https://openalex.org/W1990186831","https://openalex.org/W1993211001","https://openalex.org/W1996857045","https://openalex.org/W2000929029","https://openalex.org/W2003597177","https://openalex.org/W2003613730","https://openalex.org/W2009140755","https://openalex.org/W2010012152","https://openalex.org/W2010722299","https://openalex.org/W2014351445","https://openalex.org/W2020079102","https://openalex.org/W2023121874","https://openalex.org/W2028836221","https://openalex.org/W2030344733","https://openalex.org/W2037583363","https://openalex.org/W2039715752","https://openalex.org/W2043391865","https://openalex.org/W2044537010","https://openalex.org/W2049032689","https://openalex.org/W2049633694","https://openalex.org/W2051052300","https://openalex.org/W2061806683","https://openalex.org/W2064404921","https://openalex.org/W2067382076","https://openalex.org/W2069629287","https://openalex.org/W2077661028","https://openalex.org/W2079065942","https://openalex.org/W2085885731","https://openalex.org/W2091034493","https://openalex.org/W2107820964","https://openalex.org/W2108078594","https://openalex.org/W2108925589","https://openalex.org/W2110338249","https://openalex.org/W2112637648","https://openalex.org/W2114378747","https://openalex.org/W2117073980","https://openalex.org/W2126508627","https://openalex.org/W2129433790","https://openalex.org/W2130040053","https://openalex.org/W2130281489","https://openalex.org/W2133175443","https://openalex.org/W2133665775","https://openalex.org/W2141161788","https://openalex.org/W2144458580","https://openalex.org/W2151843995","https://openalex.org/W2154744699","https://openalex.org/W2156231908","https://openalex.org/W2159184259","https://openalex.org/W2160738239","https://openalex.org/W2162740426","https://openalex.org/W2162978906","https://openalex.org/W2168193316","https://openalex.org/W2221881442","https://openalex.org/W2270346996","https://openalex.org/W2274033742","https://openalex.org/W2281211957","https://openalex.org/W2296044681","https://openalex.org/W2304192236","https://openalex.org/W2334956335","https://openalex.org/W2462673449","https://openalex.org/W2506656898","https://openalex.org/W2510420732","https://openalex.org/W2519859955","https://openalex.org/W2541411913","https://openalex.org/W2542659327","https://openalex.org/W2544724771","https://openalex.org/W2547154487","https://openalex.org/W2556712496","https://openalex.org/W2578835425","https://openalex.org/W2602061033","https://openalex.org/W2603922658","https://openalex.org/W2609484922","https://openalex.org/W2616489368","https://openalex.org/W2619320356","https://openalex.org/W2765977226","https://openalex.org/W2766357906","https://openalex.org/W2909887812","https://openalex.org/W2914355377","https://openalex.org/W2947137705","https://openalex.org/W2952506191","https://openalex.org/W2966483281","https://openalex.org/W2969610636","https://openalex.org/W2971842491","https://openalex.org/W2994140308","https://openalex.org/W4295679829"],"related_works":["https://openalex.org/W3003187007","https://openalex.org/W2955255087","https://openalex.org/W2903637720","https://openalex.org/W2296044681","https://openalex.org/W87878379","https://openalex.org/W2008281401","https://openalex.org/W2089817993","https://openalex.org/W2570920668","https://openalex.org/W2118941648","https://openalex.org/W1988051839"],"abstract_inverted_index":{"Positron":[0],"emission":[1,226],"tomography":[2,22],"(PET)":[3],"has":[4],"an":[5,75,135],"important":[6],"role":[7],"in":[8,160,203,233,236,280,310],"disease":[9],"diagnosis,":[10],"drug":[11],"development":[12],"and":[13,52,63,103,108,184,216,227,247,257,270,304,329],"patient":[14,158],"management.":[15],"PET":[16,117,196],"images":[17,192],"are":[18],"accompanied":[19],"with":[20,50,134,208,239,264,286],"computed":[21],"(CT)":[23],"or":[24,157],"magnetic":[25],"resonance":[26],"(MR)":[27],"to":[28,91,181,193,284,316],"provide":[29,313],"the":[30,38,61,70,88,93,122,125,141,145,151,161,187,200,209,222,240,243,251,265,292,318,327],"complementary":[31],"structural":[32,271],"information.":[33],"GE":[34,71,165],"SIGNA":[35,72,166],"PET/MR":[36,73,167],"is":[37,138,180],"state-of-the-art":[39],"clinical":[40,217,335],"scanner":[41],"that":[42],"aims":[43,58],"at":[44,59],"combining":[45],"time":[46,331],"of":[47,66,127,144,153,172,177,245,295,320],"flight-PET":[48],"(TOF-PET)":[49],"anatomical":[51,188],"soft-tissue":[53],"MR":[54,191],"imaging.":[55],"This":[56,84],"work":[57,85,179],"modelling":[60],"mathematical":[62],"physical":[64],"processes":[65],"TOF-PET":[67,183,300],"data":[68,228,297,301],"for":[69,79,221,299],"within":[74,130,250],"open-source":[76],"software,":[77],"software":[78,212],"tomographic":[80],"image":[81],"reconstruction":[82,211,298,323],"(STIR).":[83],"further":[86,185],"examines":[87],"developments":[89,201,231,308],"made":[90,202,232,309],"implement":[92],"acquisition":[94],"model":[95],"using":[96,140,230,255,302,333],"typical":[97],"(ordered":[98],"subsets":[99],"expectation":[100,110],"maximisation":[101,111],"(OSEM))":[102],"advanced":[104],"iterative":[105],"algorithms":[106,259],"(TOF-OSEM":[107],"TOF-kernelised":[109],"(TOF-KEM)).":[112],"\\n":[113,198,288],"\\nTOF-PET":[114],"improves":[115],"conventional":[116],"imaging":[118],"as":[119,282],"it":[120],"localises":[121],"event":[123],"along":[124],"line":[126],"response":[128],"(LOR)":[129],"a":[131,169,261,277,314,321],"small":[132,154],"region":[133],"uncertainty":[136],"which":[137],"calculated":[139,225],"timing":[142,170],"resolution":[143,171,269],"detectors.":[146],"It":[147],"demonstrates":[148,291],"robustness":[149],"despite":[150,242],"presence":[152],"errors,":[155],"inconsistencies":[156],"motion":[159],"acquired":[162],"data.":[163],"The":[164,175,224,307],"have":[168],"390":[173],"ps.":[174],"aim":[176],"this":[178,204,311],"exploit":[182],"include":[186],"information":[189],"from":[190],"facilitate":[194],"robust":[195],"reconstructions.":[197],"\\nAll":[199],"thesis":[205,290,312],"were":[206,219,235],"compared":[207,283],"vendor's":[210],"(GE-toolbox).":[213],"Real":[214],"phantom":[215],"datasets":[218],"used":[220],"analysis.":[223,273],"corrections":[229],"STIR":[234],"excellent":[237],"agreement":[238,263],"GE-toolbox":[241,266],"absence":[244],"dead-time":[246],"decay":[248],"effects":[249,319],"current":[252],"developments.":[253],"Reconstructions":[254],"OSEM":[256],"TOF-OSEM":[258,285,303],"demonstrated":[260,276],"good":[262],"concerning":[267],"quantitative,":[268],"based":[272],"TOF-KEM":[274,305,325],"reconstructions":[275],"slight":[278],"improvement":[279],"quantification":[281],"STIR.":[287],"\\nThe":[289],"first":[293],"instance":[294],"real":[296,334],"algorithms.":[306],"platform":[315],"investigate":[317],"novel":[322],"algorithm,":[324],"on":[326],"dose":[328],"scan":[330],"reduction":[332],"datasets.":[336]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-11-09T00:00:00"}
