{"id":"https://openalex.org/W3094413616","doi":"https://doi.org/10.12688/wellcomeopenres.16374.2","title":"MendelianRandomization v0.5.0: updates to an R package for performing Mendelian randomization analyses using summarized data","display_name":"MendelianRandomization v0.5.0: updates to an R package for performing Mendelian randomization analyses using summarized data","publication_year":2020,"publication_date":"2020-10-22","ids":{"openalex":"https://openalex.org/W3094413616","doi":"https://doi.org/10.12688/wellcomeopenres.16374.2","mag":"3094413616","pmid":"https://pubmed.ncbi.nlm.nih.gov/33381656","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7745186"},"language":"en","primary_location":{"id":"doi:10.12688/wellcomeopenres.16374.2","doi":"https://doi.org/10.12688/wellcomeopenres.16374.2","is_oa":true,"landing_page_url":"https://doi.org/10.12688/wellcomeopenres.16374.2","pdf_url":"https://wellcomeopenresearch.org/articles/5-252/v2/pdf","source":{"id":"https://openalex.org/S4210218052","display_name":"Wellcome Open Research","issn_l":"2398-502X","issn":["2398-502X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311838","host_organization_name":"Wellcome","host_organization_lineage":["https://openalex.org/P4310311838"],"host_organization_lineage_names":["Wellcome"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome Open Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://wellcomeopenresearch.org/articles/5-252/v2/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069892423","display_name":"Jim R. Broadbent","orcid":"https://orcid.org/0000-0002-5685-6241","observed_orcids":["https://orcid.org/0000-0002-5685-6241"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jim R. Broadbent","raw_affiliation_strings":[". Wes Spiller , University of Bristol , Bristol , UK","Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Wes Spiller , University of Bristol , Bristol , UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044626025","display_name":"Christopher N. Foley","orcid":"https://orcid.org/0000-0002-0970-2610","observed_orcids":["https://orcid.org/0000-0002-0970-2610"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Christopher N. Foley","raw_affiliation_strings":["","MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK"],"raw_orcid":"https://orcid.org/0000-0002-0970-2610","affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210134973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006974417","display_name":"Andrew J. Grant","orcid":"https://orcid.org/0000-0001-6422-583X","observed_orcids":["https://orcid.org/0000-0001-6422-583X"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Andrew J. Grant","raw_affiliation_strings":["","MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK"],"raw_orcid":"https://orcid.org/0000-0001-6422-583X","affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210134973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026495489","display_name":"Amy M. Mason","orcid":"https://orcid.org/0000-0002-8019-0777","observed_orcids":["https://orcid.org/0000-0002-8019-0777"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Amy M. Mason","raw_affiliation_strings":[". Wes Spiller , University of Bristol , Bristol , UK","Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK"],"raw_orcid":"https://orcid.org/0000-0002-8019-0777","affiliations":[{"raw_affiliation_string":". Wes Spiller , University of Bristol , Bristol , UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090122535","display_name":"James R Staley","orcid":"https://orcid.org/0009-0001-9520-5011","observed_orcids":["https://orcid.org/0009-0001-9520-5011"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"James R. Staley","raw_affiliation_strings":["Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087932701","display_name":"Stephen Burgess","orcid":"https://orcid.org/0000-0001-5365-8760","observed_orcids":["https://orcid.org/0000-0001-5365-8760"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210134973","display_name":"MRC Biostatistics Unit","ror":"https://ror.org/046vje122","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210134973","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Stephen Burgess","raw_affiliation_strings":["Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK","MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK"],"raw_orcid":"https://orcid.org/0000-0001-5365-8760","affiliations":[{"raw_affiliation_string":"Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0SR, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"MRC Biostatistics Unit, University of Cambridge, Cambridge, CB1 8RN, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210134973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5006974417","https://openalex.org/A5026495489","https://openalex.org/A5044626025","https://openalex.org/A5069892423","https://openalex.org/A5087932701","https://openalex.org/A5090122535"],"corresponding_institution_ids":["https://openalex.org/I241749","https://openalex.org/I36234482","https://openalex.org/I4210134973"],"apc_list":{"value":920,"currency":"GBP","value_usd":1128},"apc_paid":{"value":920,"currency":"GBP","value_usd":1128},"fwci":7.479,"has_fulltext":true,"cited_by_count":151,"citation_normalized_percentile":{"value":0.98507672,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"5","issue":null,"first_page":"252","last_page":"252"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10845","display_name":"Advanced Causal Inference Techniques","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mendelian-randomization","display_name":"Mendelian randomization","score":0.9990000128746033},{"id":"https://openalex.org/keywords/multivariable-mendelian-randomization","display_name":"multivariable Mendelian randomization","score":0.9179999828338623},{"id":"https://openalex.org/keywords/robust-estimation","display_name":"robust estimation","score":0.5130000114440918},{"id":"https://openalex.org/keywords/data-visualization","display_name":"data visualization","score":0.8199999928474426},{"id":"https://openalex.org/keywords/causal-inference","display_name":"causal inference","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2779901538","wikidata":"https://www.wikidata.org/wiki/Q6816584","display_name":"Mendelian randomization","level":5,"score":0.8411051630973816},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7157056331634521},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.6811425685882568},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.541700541973114},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.5225728750228882},{"id":"https://openalex.org/C60048249","wikidata":"https://www.wikidata.org/wiki/Q37437","display_name":"Syntax","level":2,"score":0.4655360281467438},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4233369827270508},{"id":"https://openalex.org/C172367668","wikidata":"https://www.wikidata.org/wiki/Q6504956","display_name":"Data visualization","level":3,"score":0.416090726852417},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.35492202639579773},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2605261206626892},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06500720977783203},{"id":"https://openalex.org/C2993967602","wikidata":"https://www.wikidata.org/wiki/Q5532932","display_name":"Genetic variants","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.12688/wellcomeopenres.16374.2","doi":"https://doi.org/10.12688/wellcomeopenres.16374.2","is_oa":true,"landing_page_url":"https://doi.org/10.12688/wellcomeopenres.16374.2","pdf_url":"https://wellcomeopenresearch.org/articles/5-252/v2/pdf","source":{"id":"https://openalex.org/S4210218052","display_name":"Wellcome Open Research","issn_l":"2398-502X","issn":["2398-502X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311838","host_organization_name":"Wellcome","host_organization_lineage":["https://openalex.org/P4310311838"],"host_organization_lineage_names":["Wellcome"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome Open Research","raw_type":"journal-article"},{"id":"doi:10.12688/wellcomeopenres.16374.1","doi":"https://doi.org/10.12688/wellcomeopenres.16374.1","is_oa":true,"landing_page_url":"https://doi.org/10.12688/wellcomeopenres.16374.1","pdf_url":"https://wellcomeopenresearch.org/articles/5-252/v1/pdf","source":{"id":"https://openalex.org/S4210218052","display_name":"Wellcome Open Research","issn_l":"2398-502X","issn":["2398-502X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311838","host_organization_name":"Wellcome","host_organization_lineage":["https://openalex.org/P4310311838"],"host_organization_lineage_names":["Wellcome"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome Open Research","raw_type":"journal-article"},{"id":"pmid:33381656","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33381656","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome open research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7745186","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7745186/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome Open Res","raw_type":"Text"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/315937","doi":null,"is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/315937","pdf_url":"https://www.repository.cam.ac.uk/handle/1810/315937","source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:4b0e8a351cbb448585cebfcebcfb602d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4b0e8a351cbb448585cebfcebcfb602d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wellcome Open Research, Vol 5 (2020)","raw_type":"article"},{"id":"doi:10.17863/cam.63047","doi":"https://doi.org/10.17863/cam.63047","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.63047","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.12688/wellcomeopenres.16374.2","doi":"https://doi.org/10.12688/wellcomeopenres.16374.2","is_oa":true,"landing_page_url":"https://doi.org/10.12688/wellcomeopenres.16374.2","pdf_url":"https://wellcomeopenresearch.org/articles/5-252/v2/pdf","source":{"id":"https://openalex.org/S4210218052","display_name":"Wellcome Open Research","issn_l":"2398-502X","issn":["2398-502X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311838","host_organization_name":"Wellcome","host_organization_lineage":["https://openalex.org/P4310311838"],"host_organization_lineage_names":["Wellcome"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wellcome Open Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G10155507","display_name":"Genetics and causality: towards more accessible and more reliable Mendelian randomization investigations","funder_award_id":"204623/Z/16/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7399663621","display_name":"Genetics and causality: towards more accessible and more reliable Mendelian randomization investigations","funder_award_id":"204623","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319994","display_name":"Department of Health and Social Care","ror":"https://ror.org/03sbpja79"},{"id":"https://openalex.org/F4320320006","display_name":"Royal Society","ror":"https://ror.org/03wnrjx87"},{"id":"https://openalex.org/F4320320273","display_name":"University of Cambridge","ror":"https://ror.org/013meh722"},{"id":"https://openalex.org/F4320321578","display_name":"Cambridge University Hospitals","ror":"https://ror.org/04v54gj93"},{"id":"https://openalex.org/F4320336709","display_name":"NIHR Cambridge Biomedical Research Centre","ror":"https://ror.org/05m8dr349"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3094413616.pdf","grobid_xml":"https://content.openalex.org/works/W3094413616.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1810028515","https://openalex.org/W1905058580","https://openalex.org/W2106036991","https://openalex.org/W2112390338","https://openalex.org/W2113699335","https://openalex.org/W2118743532","https://openalex.org/W2153118028","https://openalex.org/W2169283889","https://openalex.org/W2198755677","https://openalex.org/W2238851414","https://openalex.org/W2324862792","https://openalex.org/W2398690791","https://openalex.org/W2581245397","https://openalex.org/W2582743722","https://openalex.org/W2597850678","https://openalex.org/W2604218568","https://openalex.org/W2613603864","https://openalex.org/W2742117056","https://openalex.org/W2805801533","https://openalex.org/W2805983714","https://openalex.org/W2884028796","https://openalex.org/W2891812515","https://openalex.org/W2949275660","https://openalex.org/W2955177623","https://openalex.org/W2963887614","https://openalex.org/W2977182596","https://openalex.org/W2991007563","https://openalex.org/W2996249643","https://openalex.org/W3014191903","https://openalex.org/W3080182863","https://openalex.org/W4210703904","https://openalex.org/W4230866720","https://openalex.org/W4253754191","https://openalex.org/W6635149568","https://openalex.org/W6912357070"],"related_works":["https://openalex.org/W4388865102","https://openalex.org/W3119936278","https://openalex.org/W2604218568","https://openalex.org/W6976915592","https://openalex.org/W7212148381","https://openalex.org/W6960022301","https://openalex.org/W2276135859","https://openalex.org/W6941488408","https://openalex.org/W2909648768","https://openalex.org/W3213054696"],"abstract_inverted_index":{"The":[0],"MendelianRandomization":[1],"package":[2,6,35,71],"is":[3],"a":[4,100,105],"software":[5,11],"written":[7],"for":[8,16,51,55,60,94],"the":[9,34,64,70,74,81,86],"R":[10],"environment":[12],"that":[13,29],"implements":[14],"methods":[15,50,54],"Mendelian":[17,52,57,101],"randomization":[18,102],"based":[19],"on":[20],"summarized":[21],"data.":[22],"In":[23],"this":[24],"manuscript,":[25],"we":[26],"describe":[27],"functions":[28,59],"have":[30],"been":[31],"added":[32],"to":[33,66],"or":[36],"updated":[37],"in":[38,104],"recent":[39],"years.":[40],"These":[41],"features":[42],"can":[43],"be":[44],"divided":[45],"into":[46,69],"four":[47],"categories:":[48],"robust":[49],"randomization,":[53,58],"multivariable":[56],"data":[61,68,87,97],"visualization,":[62],"and":[63,98],"ability":[65],"load":[67],"seamlessly":[72],"from":[73],"PhenoScanner":[75],"web-resource.":[76],"We":[77],"provide":[78],"examples":[79],"of":[80,108],"graphical":[82],"output":[83],"produced":[84],"by":[85],"visualization":[88],"commands,":[89],"as":[90,92],"well":[91],"syntax":[93],"obtaining":[95],"suitable":[96],"performing":[99],"analysis":[103],"single":[106],"line":[107],"code.":[109]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":28},{"year":2024,"cited_by_count":51},{"year":2023,"cited_by_count":27},{"year":2022,"cited_by_count":27},{"year":2021,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-10-29T00:00:00"}