{"id":"https://openalex.org/W30931427","doi":"https://doi.org/10.1007/978-1-4615-1809-9_10","title":"The role of cyclin E in the regulation of entry into S phase","display_name":"The role of cyclin E in the regulation of entry into S phase","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W30931427","doi":"https://doi.org/10.1007/978-1-4615-1809-9_10","mag":"30931427","pmid":"https://pubmed.ncbi.nlm.nih.gov/9552358"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4615-1809-9_10","doi":"https://doi.org/10.1007/978-1-4615-1809-9_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-1809-9_10","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Cell Cycle Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4300171885","display_name":"Progress in Cell Cycle Research"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082196069","display_name":"Karsten Sauer","orcid":"https://orcid.org/0000-0002-8355-9429","observed_orcids":["https://orcid.org/0000-0002-8355-9429"]},"institutions":[{"id":"https://openalex.org/I149899117","display_name":"Max Planck Society","ror":"https://ror.org/01hhn8329","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117"]},{"id":"https://openalex.org/I4210147862","display_name":"Friedrich Miescher Laboratory","ror":"https://ror.org/04vh1tq58","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210147862"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karsten Sauer","raw_affiliation_strings":["Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, T\u00fcbingen, Germany","Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Spemannstr. 37/39, D-72076, T\u00fcbingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I149899117","https://openalex.org/I4210147862"]},{"raw_affiliation_string":"Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Spemannstr. 37/39, D-72076, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I4210147862"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086562799","display_name":"Christian F. Lehner","orcid":"https://orcid.org/0000-0003-0185-6049","observed_orcids":["https://orcid.org/0000-0003-0185-6049"]},"institutions":[{"id":"https://openalex.org/I4210147862","display_name":"Friedrich Miescher Laboratory","ror":"https://ror.org/04vh1tq58","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210147862"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian F. Lehner","raw_affiliation_strings":["Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Spemannstr. 37/39, D-72076, T\u00fcbingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Spemannstr. 37/39, D-72076, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I4210147862"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1651,"has_fulltext":false,"cited_by_count":73,"citation_normalized_percentile":{"value":0.78483245,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"1","issue":null,"first_page":"125","last_page":"139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclin-e","display_name":"cyclin E","score":1.0},{"id":"https://openalex.org/keywords/s-phase-entry","display_name":"S phase entry","score":0.7580000162124634},{"id":"https://openalex.org/keywords/cdk2","display_name":"CDK2","score":0.8899999856948853},{"id":"https://openalex.org/keywords/dna-replication-initiation","display_name":"DNA replication initiation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9139999747276306}],"concepts":[{"id":"https://openalex.org/C94561458","wikidata":"https://www.wikidata.org/wiki/Q24724860","display_name":"Cyclin E","level":5,"score":0.8025082349777222},{"id":"https://openalex.org/C16438837","wikidata":"https://www.wikidata.org/wiki/Q5198260","display_name":"Cyclin A","level":5,"score":0.7674230337142944},{"id":"https://openalex.org/C11882975","wikidata":"https://www.wikidata.org/wiki/Q24781041","display_name":"Cyclin D","level":5,"score":0.7355362772941589},{"id":"https://openalex.org/C28179978","wikidata":"https://www.wikidata.org/wiki/Q5198263","display_name":"Cyclin A2","level":5,"score":0.6736780405044556},{"id":"https://openalex.org/C175738201","wikidata":"https://www.wikidata.org/wiki/Q5198255","display_name":"Cyclin-dependent kinase complex","level":5,"score":0.6683826446533203},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.646774411201477},{"id":"https://openalex.org/C120089663","wikidata":"https://www.wikidata.org/wiki/Q59250999","display_name":"Cyclin","level":4,"score":0.5255816578865051},{"id":"https://openalex.org/C82495950","wikidata":"https://www.wikidata.org/wiki/Q14911732","display_name":"Cyclin-dependent kinase 2","level":4,"score":0.5023412704467773},{"id":"https://openalex.org/C9743823","wikidata":"https://www.wikidata.org/wiki/Q5198264","display_name":"Cyclin B","level":5,"score":0.4750654399394989},{"id":"https://openalex.org/C35195891","wikidata":"https://www.wikidata.org/wiki/Q2289513","display_name":"S phase","level":5,"score":0.41480231285095215},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38703471422195435},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.38354864716529846},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3453383147716522},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.2810520827770233},{"id":"https://openalex.org/C73573662","wikidata":"https://www.wikidata.org/wiki/Q130996","display_name":"DNA replication","level":3,"score":0.24115413427352905},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.23562639951705933},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.1675530970096588},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.16358840465545654},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15734103322029114},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13252407312393188},{"id":"https://openalex.org/C98086919","wikidata":"https://www.wikidata.org/wiki/Q118019","display_name":"Eukaryotic DNA replication","level":4,"score":0.09932675957679749}],"mesh":[{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005057","descriptor_name":"Eukaryotic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016196","descriptor_name":"S Phase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017346","descriptor_name":"Protein Serine-Threonine Kinases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018844","descriptor_name":"Cyclin-Dependent Kinases","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019927","descriptor_name":"Cyclin E","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D042846","descriptor_name":"CDC2-CDC28 Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051357","descriptor_name":"Cyclin-Dependent Kinase 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4615-1809-9_10","doi":"https://doi.org/10.1007/978-1-4615-1809-9_10","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-1809-9_10","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Cell Cycle Research","raw_type":"book-chapter"},{"id":"pmid:9552358","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9552358","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in cell cycle research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":143,"referenced_works":["https://openalex.org/W16019424","https://openalex.org/W81266651","https://openalex.org/W82810333","https://openalex.org/W93220107","https://openalex.org/W102905955","https://openalex.org/W128824071","https://openalex.org/W139338291","https://openalex.org/W149894293","https://openalex.org/W152730474","https://openalex.org/W159450053","https://openalex.org/W163050607","https://openalex.org/W174741394","https://openalex.org/W196685199","https://openalex.org/W327522344","https://openalex.org/W1483839132","https://openalex.org/W1529783836","https://openalex.org/W1534302336","https://openalex.org/W1536498570","https://openalex.org/W1539182448","https://openalex.org/W1544564404","https://openalex.org/W1567107115","https://openalex.org/W1594985705","https://openalex.org/W1659722210","https://openalex.org/W1684855778","https://openalex.org/W1778446120","https://openalex.org/W1834547194","https://openalex.org/W1845790496","https://openalex.org/W1868808920","https://openalex.org/W1910656974","https://openalex.org/W1923453853","https://openalex.org/W1923636344","https://openalex.org/W1932627063","https://openalex.org/W1952982568","https://openalex.org/W1964429281","https://openalex.org/W1964658039","https://openalex.org/W1966797025","https://openalex.org/W1970783685","https://openalex.org/W1971245466","https://openalex.org/W1973360767","https://openalex.org/W1973461983","https://openalex.org/W1975324295","https://openalex.org/W1975939844","https://openalex.org/W1977299280","https://openalex.org/W1979669293","https://openalex.org/W1980720313","https://openalex.org/W1982245444","https://openalex.org/W1982622947","https://openalex.org/W1983302698","https://openalex.org/W1990925999","https://openalex.org/W1991101546","https://openalex.org/W1994066190","https://openalex.org/W1994082723","https://openalex.org/W1996413533","https://openalex.org/W1996931202","https://openalex.org/W1997012271","https://openalex.org/W1997408971","https://openalex.org/W1997643531","https://openalex.org/W1999862535","https://openalex.org/W1999876280","https://openalex.org/W2003907692","https://openalex.org/W2004497068","https://openalex.org/W2005941837","https://openalex.org/W2007772649","https://openalex.org/W2008693579","https://openalex.org/W2009261150","https://openalex.org/W2012293213","https://openalex.org/W2014222675","https://openalex.org/W2015519364","https://openalex.org/W2023536598","https://openalex.org/W2024849327","https://openalex.org/W2027376766","https://openalex.org/W2035189704","https://openalex.org/W2035369088","https://openalex.org/W2036647778","https://openalex.org/W2036817346","https://openalex.org/W2038407368","https://openalex.org/W2038765811","https://openalex.org/W2039201695","https://openalex.org/W2039263836","https://openalex.org/W2041372335","https://openalex.org/W2041555818","https://openalex.org/W2044279758","https://openalex.org/W2048721919","https://openalex.org/W2048743150","https://openalex.org/W2048966002","https://openalex.org/W2052221882","https://openalex.org/W2053425283","https://openalex.org/W2057318654","https://openalex.org/W2059594509","https://openalex.org/W2061941936","https://openalex.org/W2063856790","https://openalex.org/W2064153193","https://openalex.org/W2064994017","https://openalex.org/W2065252383","https://openalex.org/W2065797900","https://openalex.org/W2066125587","https://openalex.org/W2066848701","https://openalex.org/W2070061120","https://openalex.org/W2072897152","https://openalex.org/W2073166133","https://openalex.org/W2074126694","https://openalex.org/W2075227844","https://openalex.org/W2076273397","https://openalex.org/W2078427074","https://openalex.org/W2078596153","https://openalex.org/W2085129915","https://openalex.org/W2086693806","https://openalex.org/W2089218510","https://openalex.org/W2089921983","https://openalex.org/W2090303261","https://openalex.org/W2091038230","https://openalex.org/W2091877548","https://openalex.org/W2092104789","https://openalex.org/W2092776018","https://openalex.org/W2093915334","https://openalex.org/W2097043033","https://openalex.org/W2098412103","https://openalex.org/W2103700842","https://openalex.org/W2111352802","https://openalex.org/W2112555367","https://openalex.org/W2125555976","https://openalex.org/W2128739161","https://openalex.org/W2133697463","https://openalex.org/W2134331780","https://openalex.org/W2144942522","https://openalex.org/W2147242002","https://openalex.org/W2153488262","https://openalex.org/W2154366922","https://openalex.org/W2155507858","https://openalex.org/W2156787082","https://openalex.org/W2163913450","https://openalex.org/W2181735616","https://openalex.org/W2185571529","https://openalex.org/W2189281745","https://openalex.org/W2191115168","https://openalex.org/W2270599862","https://openalex.org/W2294290446","https://openalex.org/W2342265972","https://openalex.org/W2399837895","https://openalex.org/W2400040529","https://openalex.org/W4231271646","https://openalex.org/W4234875475","https://openalex.org/W4256143369"],"related_works":["https://openalex.org/W4211194339","https://openalex.org/W4235437109","https://openalex.org/W71535817","https://openalex.org/W2045463072","https://openalex.org/W1972434237","https://openalex.org/W2064550856","https://openalex.org/W2084796662","https://openalex.org/W1569755992","https://openalex.org/W2146813580","https://openalex.org/W2152028923"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}