{"id":"https://openalex.org/W3093061006","doi":"https://doi.org/10.1038/s41598-020-74293-5","title":"Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility","display_name":"Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility","publication_year":2020,"publication_date":"2020-10-14","ids":{"openalex":"https://openalex.org/W3093061006","doi":"https://doi.org/10.1038/s41598-020-74293-5","mag":"3093061006","pmid":"https://pubmed.ncbi.nlm.nih.gov/33057211","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7560829"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-020-74293-5","doi":"https://doi.org/10.1038/s41598-020-74293-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-020-74293-5","pdf_url":"https://www.nature.com/articles/s41598-020-74293-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-020-74293-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009862848","display_name":"Sally Yepes","orcid":"https://orcid.org/0000-0002-6791-0434","observed_orcids":["https://orcid.org/0000-0002-6791-0434"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sally Yepes","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. sally.yepestorres@nih.gov","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. sally.yepestorres@nih.gov","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057142749","display_name":"Margaret Anne Tucker","orcid":"https://orcid.org/0000-0003-0274-6773","observed_orcids":["https://orcid.org/0000-0003-0274-6773"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret A. Tucker","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069043391","display_name":"Hela Koka","orcid":"https://orcid.org/0000-0002-3669-9429","observed_orcids":["https://orcid.org/0000-0002-3669-9429"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hela Koka","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010098599","display_name":"Yanzi Xiao","orcid":"https://orcid.org/0000-0001-9263-9749","observed_orcids":["https://orcid.org/0000-0001-9263-9749"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanzi Xiao","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039857143","display_name":"Kristine M. Jones","orcid":"https://orcid.org/0000-0003-1584-8920","observed_orcids":["https://orcid.org/0000-0003-1584-8920"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristine Jones","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088723856","display_name":"Aur\u00e9lie L. Vogt","orcid":"https://orcid.org/0000-0003-1257-3095","observed_orcids":["https://orcid.org/0000-0003-1257-3095"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aurelie Vogt","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036521868","display_name":"Laurie A. Burdette","orcid":"https://orcid.org/0000-0002-9173-7483","observed_orcids":["https://orcid.org/0000-0002-9173-7483"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurie Burdette","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028834004","display_name":"Wen Luo","orcid":"https://orcid.org/0000-0002-3558-4136","observed_orcids":["https://orcid.org/0000-0002-3558-4136"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen Luo","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076808228","display_name":"Bin Zhu","orcid":"https://orcid.org/0000-0003-0172-5516","observed_orcids":["https://orcid.org/0000-0003-0172-5516"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin Zhu","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088697436","display_name":"Amy A Hutchinson","orcid":"https://orcid.org/0000-0002-4962-2711","observed_orcids":["https://orcid.org/0000-0002-4962-2711"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Hutchinson","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103252071","display_name":"Meredith Yeager","orcid":"https://orcid.org/0000-0003-3871-2225","observed_orcids":["https://orcid.org/0000-0003-3871-2225"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meredith Yeager","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067533895","display_name":"Belynda D. Hicks","orcid":"https://orcid.org/0000-0001-8014-4888","observed_orcids":["https://orcid.org/0000-0001-8014-4888"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Belynda Hicks","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089976309","display_name":"Neal D. Freedman","orcid":"https://orcid.org/0000-0003-0074-1098","observed_orcids":["https://orcid.org/0000-0003-0074-1098"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neal D. Freedman","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091653870","display_name":"Stephen Jacob Chanock","orcid":"https://orcid.org/0000-0002-2324-3393","observed_orcids":["https://orcid.org/0000-0002-2324-3393"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Chanock","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063007431","display_name":"Alisa M. Goldstein","orcid":"https://orcid.org/0000-0002-7538-3582","observed_orcids":["https://orcid.org/0000-0002-7538-3582"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alisa M. Goldstein","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038423396","display_name":"Xiaohong Rose Yang","orcid":"https://orcid.org/0000-0003-4451-8664","observed_orcids":["https://orcid.org/0000-0003-4451-8664"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xiaohong R. Yang","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. royang@mail.nih.gov","Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. royang@mail.nih.gov","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]},{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4391012607"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5009862848","https://openalex.org/A5038423396"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"],"apc_list":{"value":1870,"currency":"USD","value_usd":1870},"apc_paid":{"value":1870,"currency":"USD","value_usd":1870},"fwci":0.4864,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.57016105,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"1","first_page":"17198","last_page":"17198"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6664999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.6664999723434448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.3041999936103821,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cutaneous-melanoma","display_name":"cutaneous melanoma","score":0.953000009059906},{"id":"https://openalex.org/keywords/candidate-gene-prioritization","display_name":"candidate gene prioritization","score":0.859000027179718},{"id":"https://openalex.org/keywords/protein-protein-interaction-network","display_name":"protein-protein interaction network","score":0.9850000143051147},{"id":"https://openalex.org/keywords/network-propagation","display_name":"network propagation","score":0.9729999899864197},{"id":"https://openalex.org/keywords/genetic-heterogeneity","display_name":"genetic heterogeneity","score":0.7419999837875366},{"id":"https://openalex.org/keywords/familial-melanoma","display_name":"familial melanoma","score":0.8709999918937683},{"id":"https://openalex.org/keywords/ngly1","display_name":"NGLY1","score":0.9210000038146973},{"id":"https://openalex.org/keywords/interleukin-1-receptor-antagonist","display_name":"interleukin-1 receptor antagonist","score":0.996999979019165},{"id":"https://openalex.org/keywords/fabp2","display_name":"FABP2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prkdc","display_name":"PRKDC","score":1.0},{"id":"https://openalex.org/keywords/gene-clusters","display_name":"gene clusters","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.8107930421829224},{"id":"https://openalex.org/C16671776","wikidata":"https://www.wikidata.org/wiki/Q5420592","display_name":"Exome sequencing","level":4,"score":0.6939750909805298},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.651313304901123},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5865961313247681},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5642905235290527},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5639193058013916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5413416028022766},{"id":"https://openalex.org/C10590036","wikidata":"https://www.wikidata.org/wiki/Q417664","display_name":"Exome","level":5,"score":0.5375764966011047},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.4443749785423279},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.43065330386161804},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.14596235752105713},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0795569121837616},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D000096142","descriptor_name":"Cutaneous Malignant Melanoma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005854","descriptor_name":"Germ Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018740","descriptor_name":"Genetic Heterogeneity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059472","descriptor_name":"Exome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D060066","descriptor_name":"Protein Interaction Maps","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1038/s41598-020-74293-5","doi":"https://doi.org/10.1038/s41598-020-74293-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-020-74293-5","pdf_url":"https://www.nature.com/articles/s41598-020-74293-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7560829","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7560829","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmid:33057211","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33057211","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/s41598-020-74293-5","doi":"https://doi.org/10.1038/s41598-020-74293-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-020-74293-5","pdf_url":"https://www.nature.com/articles/s41598-020-74293-5.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320338333","display_name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute","ror":"https://ror.org/00vkwep27"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3093061006.pdf","grobid_xml":"https://content.openalex.org/works/W3093061006.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1950829641","https://openalex.org/W1967925809","https://openalex.org/W1985213868","https://openalex.org/W1989277387","https://openalex.org/W1989590412","https://openalex.org/W2016661249","https://openalex.org/W2024663595","https://openalex.org/W2038122249","https://openalex.org/W2045870710","https://openalex.org/W2081375228","https://openalex.org/W2083045667","https://openalex.org/W2086095857","https://openalex.org/W2088544963","https://openalex.org/W2099656145","https://openalex.org/W2100582962","https://openalex.org/W2114540504","https://openalex.org/W2118607021","https://openalex.org/W2119220491","https://openalex.org/W2124649441","https://openalex.org/W2125910575","https://openalex.org/W2128416360","https://openalex.org/W2129952088","https://openalex.org/W2138300856","https://openalex.org/W2140883620","https://openalex.org/W2143625465","https://openalex.org/W2145752531","https://openalex.org/W2151854382","https://openalex.org/W2159675211","https://openalex.org/W2162066233","https://openalex.org/W2166542841","https://openalex.org/W2173732482","https://openalex.org/W2330012690","https://openalex.org/W2468797021","https://openalex.org/W2498949496","https://openalex.org/W2558534012","https://openalex.org/W2611187032","https://openalex.org/W2624021832","https://openalex.org/W2750998426","https://openalex.org/W2761934863","https://openalex.org/W2890112540","https://openalex.org/W4211020617","https://openalex.org/W4231254854","https://openalex.org/W6813094581"],"related_works":["https://openalex.org/W2953884719","https://openalex.org/W4212802425","https://openalex.org/W2901873619","https://openalex.org/W3015915664","https://openalex.org/W4210258955","https://openalex.org/W2986489854","https://openalex.org/W2509231115","https://openalex.org/W2308579224","https://openalex.org/W2981134195","https://openalex.org/W2104622981"],"abstract_inverted_index":{"Although":[0],"next-generation":[1],"sequencing":[2,33],"has":[3],"demonstrated":[4],"great":[5],"potential":[6,143],"for":[7,129],"novel":[8],"gene":[9,65,130],"discovery,":[10],"confirming":[11],"disease-causing":[12],"genes":[13,29,51,58,79,108,114,146],"after":[14],"initial":[15],"discovery":[16],"remains":[17],"challenging.":[18],"Here,":[19],"we":[20,48,73],"applied":[21],"a":[22,44],"network":[23,45,94],"analysis":[24,34,95,127],"approach":[25],"to":[26,55,99],"prioritize":[27],"candidate":[28,50,77,144],"identified":[30,64,74],"from":[31,40],"whole-exome":[32],"of":[35,135],"98":[36],"cutaneous":[37],"melanoma":[38],"patients":[39],"27":[41],"families.":[42],"Using":[43,70],"propagation":[46],"method,":[47],"ranked":[49],"by":[52],"their":[53],"similarity":[54],"known":[56],"disease":[57],"in":[59,113,132,147],"protein-protein":[60,118],"interaction":[61,119],"networks":[62],"and":[63,90,140],"clusters":[66],"with":[67],"functional":[68],"connectivity.":[69],"this":[71],"approach,":[72],"several":[75],"new":[76],"susceptibility":[78,145],"that":[80,102,110,115],"warrant":[81],"future":[82],"investigations":[83],"such":[84],"as":[85],"NGLY1,":[86],"IL1RN,":[87],"FABP2,":[88],"PRKDC,":[89],"PROSER2.":[91],"The":[92],"propagated":[93],"also":[96],"allowed":[97],"us":[98],"link":[100],"families":[101,139],"did":[103],"not":[104],"have":[105],"common":[106],"underlying":[107],"but":[109],"carried":[111],"variants":[112],"interact":[116],"on":[117],"networks.":[120],"In":[121],"conclusion,":[122],"our":[123,148],"study":[124],"provided":[125],"an":[126],"perspective":[128],"prioritization":[131],"the":[133],"context":[134],"genetic":[136],"heterogeneity":[137],"across":[138],"prioritized":[141],"top":[142],"dataset.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-10-22T00:00:00"}
