{"id":"https://openalex.org/W3092239286","doi":"https://doi.org/10.1016/j.bioactmat.2020.09.027","title":"Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway","display_name":"Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway","publication_year":2020,"publication_date":"2020-10-09","ids":{"openalex":"https://openalex.org/W3092239286","doi":"https://doi.org/10.1016/j.bioactmat.2020.09.027","mag":"3092239286","pmid":"https://pubmed.ncbi.nlm.nih.gov/33102941","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7560590"},"language":"en","primary_location":{"id":"doi:10.1016/j.bioactmat.2020.09.027","doi":"https://doi.org/10.1016/j.bioactmat.2020.09.027","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioactmat.2020.09.027","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2452199X20302474/pdf","source":{"id":"https://openalex.org/S2898508902","display_name":"Bioactive Materials","issn_l":"2097-1192","issn":["2097-1192","2452-199X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2452199X20302474/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101580101","display_name":"Na Sun","orcid":"https://orcid.org/0000-0002-0888-3181","observed_orcids":["https://orcid.org/0000-0002-0888-3181"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Na Sun","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035480473","display_name":"Xiaoqiu Dou","orcid":"https://orcid.org/0000-0001-5551-965X","observed_orcids":["https://orcid.org/0000-0001-5551-965X","https://orcid.org/0009-0007-2494-5972"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4391767745","display_name":"State Key Laboratory of Metal Matrix Composites","ror":"https://ror.org/031z5jh56","country_code":"CN","type":"facility","lineage":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoqiu Dou","raw_affiliation_strings":["State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107678406","display_name":"Zhimin Tang","orcid":"https://orcid.org/0000-0003-1060-3705","observed_orcids":["https://orcid.org/0000-0003-1060-3705"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhimin Tang","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100386761","display_name":"Dandan Zhang","orcid":"https://orcid.org/0000-0001-8234-7603","observed_orcids":["https://orcid.org/0000-0001-8234-7603"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dandan Zhang","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ni Ni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ni Ni","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jiajing Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiajing Wang","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057639912","display_name":"Huiqin Gao","orcid":"https://orcid.org/0000-0001-7395-601X","observed_orcids":["https://orcid.org/0000-0001-7395-601X"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiqin Gao","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030390276","display_name":"Yahan Ju","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yahan Ju","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026988769","display_name":"Xiaochan Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaochan Dai","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000461502","display_name":"Changli Zhao","orcid":"https://orcid.org/0000-0003-1350-8682","observed_orcids":["https://orcid.org/0000-0003-1350-8682"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4391767745","display_name":"State Key Laboratory of Metal Matrix Composites","ror":"https://ror.org/031z5jh56","country_code":"CN","type":"facility","lineage":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changli Zhao","raw_affiliation_strings":["State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101415554","display_name":"Ping Gu","orcid":"https://orcid.org/0000-0002-0154-1664","observed_orcids":["https://orcid.org/0000-0002-0154-1664"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ping Gu","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438199","display_name":"Jing Ji","orcid":"https://orcid.org/0000-0001-9486-0236","observed_orcids":["https://orcid.org/0000-0001-9486-0236"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jing Ji","raw_affiliation_strings":["Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050379646","display_name":"Chuanliang Feng","orcid":"https://orcid.org/0000-0001-6137-5568","observed_orcids":["https://orcid.org/0000-0001-6137-5568"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4391767745","display_name":"State Key Laboratory of Metal Matrix Composites","ror":"https://ror.org/031z5jh56","country_code":"CN","type":"facility","lineage":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chuanliang Feng","raw_affiliation_strings":["State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Road 800, 200240, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4391767745"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5035480473","https://openalex.org/A5050379646","https://openalex.org/A5100438199","https://openalex.org/A5101415554"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066","https://openalex.org/I4391767745"],"apc_list":{"value":630,"currency":"USD","value_usd":630},"apc_paid":{"value":630,"currency":"USD","value_usd":630},"fwci":1.2712,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.75269079,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"6","issue":"4","first_page":"990","last_page":"997"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.1031000018119812,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-progenitor-cells","display_name":"retinal progenitor cells","score":0.9480000138282776},{"id":"https://openalex.org/keywords/neuronal-differentiation","display_name":"neuronal differentiation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/retinol-binding-protein-4","display_name":"retinol-binding protein 4","score":0.8830000162124634},{"id":"https://openalex.org/keywords/retinoic-acid-metabolism","display_name":"retinoic acid metabolism","score":0.9279999732971191},{"id":"https://openalex.org/keywords/retinal-degeneration","display_name":"retinal degeneration","score":0.9120000004768372},{"id":"https://openalex.org/keywords/stem-cell-transplantation","display_name":"stem cell transplantation","score":0.8679999709129333},{"id":"https://openalex.org/keywords/helical-nanofibers","display_name":"helical nanofibers","score":0.7770000100135803},{"id":"https://openalex.org/keywords/biomimetic-materials","display_name":"biomimetic materials","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C91129048","wikidata":"https://www.wikidata.org/wiki/Q594196","display_name":"Nanofiber","level":2,"score":0.7099158763885498},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5796443819999695},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.526925265789032},{"id":"https://openalex.org/C2781121885","wikidata":"https://www.wikidata.org/wiki/Q425517","display_name":"Retinoic acid","level":3,"score":0.5220817923545837},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.5161712765693665},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5033535361289978},{"id":"https://openalex.org/C124668440","wikidata":"https://www.wikidata.org/wiki/Q2305173","display_name":"Chirality (physics)","level":5,"score":0.49428653717041016},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.41201668977737427},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4114390015602112},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.34418272972106934},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2984364628791809},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2908726930618286},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28255003690719604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.270530641078949},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08827966451644897},{"id":"https://openalex.org/C7602139","wikidata":"https://www.wikidata.org/wiki/Q6718","display_name":"Quark","level":2,"score":0.0},{"id":"https://openalex.org/C20621625","wikidata":"https://www.wikidata.org/wiki/Q6961432","display_name":"Nambu\u2013Jona-Lasinio model","level":4,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C52703039","wikidata":"https://www.wikidata.org/wiki/Q5101837","display_name":"Chiral symmetry breaking","level":3,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bioactmat.2020.09.027","doi":"https://doi.org/10.1016/j.bioactmat.2020.09.027","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioactmat.2020.09.027","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2452199X20302474/pdf","source":{"id":"https://openalex.org/S2898508902","display_name":"Bioactive Materials","issn_l":"2097-1192","issn":["2097-1192","2452-199X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive Materials","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7560590","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7560590","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioact Mater","raw_type":"Text"},{"id":"pmid:33102941","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33102941","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive materials","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a6d9cc4aeb4e4ebb9c8ac50d7b6eb666","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a6d9cc4aeb4e4ebb9c8ac50d7b6eb666","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioactive Materials, Vol 6, Iss 4, Pp 990-997 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.bioactmat.2020.09.027","doi":"https://doi.org/10.1016/j.bioactmat.2020.09.027","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bioactmat.2020.09.027","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2452199X20302474/pdf","source":{"id":"https://openalex.org/S2898508902","display_name":"Bioactive Materials","issn_l":"2097-1192","issn":["2097-1192","2452-199X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioactive Materials","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9074000120162964}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3383567581","display_name":null,"funder_award_id":"WF540162603","funder_id":"https://openalex.org/F4320322999","funder_display_name":"Shanghai Jiao Tong University"},{"id":"https://openalex.org/G4227428195","display_name":"\u624b\u6027\u6c34\u51dd\u80f6\u7684\u4eff\u751f\u6784\u7b51\u53ca\u6027\u80fd\u7814\u7a76","funder_award_id":"51833006","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G597111912","display_name":null,"funder_award_id":"17DZ2260100","funder_id":"https://openalex.org/F4320322999","funder_display_name":"Shanghai Jiao Tong University"},{"id":"https://openalex.org/G7441803438","display_name":null,"funder_award_id":"17DZ2260100","funder_id":"https://openalex.org/F4320321881","funder_display_name":"Shanghai Municipal Education Commission"},{"id":"https://openalex.org/G7858070403","display_name":null,"funder_award_id":"201701070002E00061","funder_id":"https://openalex.org/F4320321881","funder_display_name":"Shanghai Municipal Education Commission"},{"id":"https://openalex.org/G8680341571","display_name":null,"funder_award_id":"17DZ2260100","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G94588278","display_name":null,"funder_award_id":"201701070002E00061","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321881","display_name":"Shanghai Municipal Education Commission","ror":"https://ror.org/05tewj457"},{"id":"https://openalex.org/F4320322999","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04"},{"id":"https://openalex.org/F4320328346","display_name":"Shanghai Municipal Health and Family Planning Commission","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320336652","display_name":"Science and Technology Innovation Plan Of Shanghai Science and Technology Commission","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3092239286.pdf","grobid_xml":"https://content.openalex.org/works/W3092239286.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1973565169","https://openalex.org/W1976499671","https://openalex.org/W1978487480","https://openalex.org/W1993547105","https://openalex.org/W1996854381","https://openalex.org/W2003570396","https://openalex.org/W2014027110","https://openalex.org/W2035266068","https://openalex.org/W2053891383","https://openalex.org/W2064519382","https://openalex.org/W2076505093","https://openalex.org/W2076602698","https://openalex.org/W2081092833","https://openalex.org/W2127137933","https://openalex.org/W2161605421","https://openalex.org/W2301137156","https://openalex.org/W2336282300","https://openalex.org/W2360077602","https://openalex.org/W2482896977","https://openalex.org/W2512813967","https://openalex.org/W2515756028","https://openalex.org/W2610808603","https://openalex.org/W2766066029","https://openalex.org/W2766224203","https://openalex.org/W2773857302","https://openalex.org/W2778237304","https://openalex.org/W2801946194","https://openalex.org/W2903944026","https://openalex.org/W2913938658","https://openalex.org/W2947145241","https://openalex.org/W2978056881","https://openalex.org/W3011162729","https://openalex.org/W3013443679","https://openalex.org/W3033037061","https://openalex.org/W3033991034"],"related_works":["https://openalex.org/W4292189631","https://openalex.org/W4293106120","https://openalex.org/W7222291667","https://openalex.org/W4382393538","https://openalex.org/W4407349024","https://openalex.org/W2186831859","https://openalex.org/W2145517046","https://openalex.org/W7204805816","https://openalex.org/W3093695186","https://openalex.org/W2011988642"],"abstract_inverted_index":{"Retinal":[0],"degeneration":[1],"is":[2],"a":[3,103],"main":[4],"class":[5],"of":[6,54,115,124,130],"ocular":[7],"diseases.":[8],"So":[9],"far,":[10],"retinal":[11],"progenitor":[12],"cell":[13],"(RPC)":[14],"transplantation":[15],"has":[16],"been":[17],"the":[18,91,107],"most":[19],"potential":[20],"therapy":[21],"for":[22,122],"it,":[23],"in":[24,106],"which":[25],"promoting":[26],"RPCs":[27,59,75],"neuronal":[28,76,117],"differentiation":[29,118,129],"remains":[30],"an":[31],"unmet":[32],"challenge.":[33],"To":[34],"address":[35],"this":[36,83],"issue,":[37],"innovatively":[38],"designed":[39],"L/d-phenylalanine":[40],"based":[41],"chiral":[42,95,135],"nanofibers":[43,72,81,97],"(LPG":[44],"and":[45,49,64,98],"DPG)":[46],"are":[47,87],"employed":[48],"it":[50],"finds":[51],"that":[52,68],"chirality":[53],"fibers":[55],"can":[56],"efficiently":[57],"regulate":[58],"differentiation.":[60],"qPCR,":[61],"western":[62],"blot,":[63],"immunofluorescence":[65],"analysis":[66],"show":[67],"right-handed":[69],"helical":[70,96],"DPG":[71],"significantly":[73],"promote":[74],"differentiation,":[77],"whereas":[78],"left-handed":[79],"LPG":[80],"decrease":[82],"effect.":[84],"These":[85],"effects":[86],"mainly":[88],"ascribed":[89],"to":[90],"stereoselective":[92],"interaction":[93],"between":[94],"retinol-binding":[99],"protein":[100,105],"4":[101],"(RBP4,":[102],"key":[104],"retinoic":[108],"acid":[109],"(RA)":[110],"metabolic":[111],"pathway).":[112],"The":[113],"findings":[114],"chirality-dependent":[116],"provide":[119],"new":[120],"strategies":[121],"treatment":[123],"neurodegenerative":[125],"diseases":[126],"via":[127],"optimizing":[128],"transplanted":[131],"stem":[132],"cells":[133],"on":[134],"nanofibers.":[136]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-10-15T00:00:00"}