{"id":"https://openalex.org/W3092106937","doi":"https://doi.org/10.1038/s41467-020-18833-7","title":"One-pot biocatalytic route from cycloalkanes to \u03b1,\u03c9\u2010dicarboxylic acids by designed Escherichia coli consortia","display_name":"One-pot biocatalytic route from cycloalkanes to \u03b1,\u03c9\u2010dicarboxylic acids by designed Escherichia coli consortia","publication_year":2020,"publication_date":"2020-10-07","ids":{"openalex":"https://openalex.org/W3092106937","doi":"https://doi.org/10.1038/s41467-020-18833-7","mag":"3092106937","pmid":"https://pubmed.ncbi.nlm.nih.gov/33028823","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7542165"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-020-18833-7","doi":"https://doi.org/10.1038/s41467-020-18833-7","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-020-18833-7","pdf_url":"https://www.nature.com/articles/s41467-020-18833-7.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-020-18833-7.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100455718","display_name":"Fei Wang","orcid":"https://orcid.org/0000-0001-6428-5111","observed_orcids":["https://orcid.org/0000-0001-6428-5111","https://orcid.org/0000-0001-7949-6114"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Wang","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040614582","display_name":"Jing Bo Zhao","orcid":"https://orcid.org/0000-0002-0305-9791","observed_orcids":["https://orcid.org/0000-0002-0305-9791"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zhao","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114023462","display_name":"Qian Li","orcid":"https://orcid.org/0009-0002-5822-9185","observed_orcids":["https://orcid.org/0009-0002-5822-9185"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Li","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102946452","display_name":"Jun Yang","orcid":"https://orcid.org/0000-0003-3739-7067","observed_orcids":["https://orcid.org/0000-0003-3739-7067"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Yang","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100442481","display_name":"Renjie Li","orcid":"https://orcid.org/0000-0002-8928-6003","observed_orcids":["https://orcid.org/0000-0002-8928-6003"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Renjie Li","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054314711","display_name":"Jian Min","orcid":"https://orcid.org/0000-0002-6341-2462","observed_orcids":["https://orcid.org/0000-0002-6341-2462"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Min","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101492415","display_name":"Xiaojuan Yu","orcid":"https://orcid.org/0000-0003-0524-5915","observed_orcids":["https://orcid.org/0000-0003-0524-5915"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaojuan Yu","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026230284","display_name":"Gao\u2010Wei Zheng","orcid":"https://orcid.org/0000-0001-5918-6047","observed_orcids":["https://orcid.org/0000-0001-5918-6047"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gao-Wei Zheng","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering and Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, 200237, Shanghai, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-5918-6047","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering and Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, 200237, Shanghai, P. R. China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089934895","display_name":"Hui\u2010Lei Yu","orcid":"https://orcid.org/0000-0002-1925-3679","observed_orcids":["https://orcid.org/0000-0002-1925-3679"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I4391768089","display_name":"State Key Laboratory of Bioreactor Engineering","ror":"https://ror.org/02hqczw19","country_code":"CN","type":"facility","lineage":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui-Lei Yu","raw_affiliation_strings":["State Key Laboratory of Bioreactor Engineering and Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, 200237, Shanghai, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Bioreactor Engineering and Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, 200237, Shanghai, P. R. China","institution_ids":["https://openalex.org/I143593769","https://openalex.org/I4391768089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101464897","display_name":"Chao Zhai","orcid":"https://orcid.org/0000-0002-4625-3068","observed_orcids":["https://orcid.org/0000-0002-4625-3068"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Zhai","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084900396","display_name":"Carlos G. Acevedo\u2010Rocha","orcid":"https://orcid.org/0000-0002-5877-2084","observed_orcids":["https://orcid.org/0000-0002-5877-2084"]},"institutions":[{"id":"https://openalex.org/I4210094627","display_name":"Biosyntia (Denmark)","ror":"https://ror.org/00mtmnw70","country_code":"DK","type":"company","lineage":["https://openalex.org/I4210094627"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Carlos G. Acevedo-Rocha","raw_affiliation_strings":["Biosyntia ApS, 2100, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-5877-2084","affiliations":[{"raw_affiliation_string":"Biosyntia ApS, 2100, Copenhagen, Denmark","institution_ids":["https://openalex.org/I4210094627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108381801","display_name":"Lixin Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lixin Ma","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":"https://orcid.org/0000-0002-2016-9781","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087131065","display_name":"Aitao Li","orcid":"https://orcid.org/0000-0001-6036-4058","observed_orcids":["https://orcid.org/0000-0001-6036-4058"]},"institutions":[{"id":"https://openalex.org/I4405271183","display_name":"State Key Laboratory of Biocatalysis and Enzyme Engineering","ror":"https://ror.org/020tz4h34","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271183"]},{"id":"https://openalex.org/I75900474","display_name":"Hubei University","ror":"https://ror.org/03a60m280","country_code":"CN","type":"education","lineage":["https://openalex.org/I75900474"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Aitao Li","raw_affiliation_strings":["State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China. aitaoli@hubu.edu.cn","State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-6036-4058","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China. aitaoli@hubu.edu.cn","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]},{"raw_affiliation_string":"State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, 430062, Wuhan, P. R. China","institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5087131065"],"corresponding_institution_ids":["https://openalex.org/I4405271183","https://openalex.org/I75900474"],"apc_list":{"value":5380,"currency":"USD","value_usd":5380},"apc_paid":{"value":5380,"currency":"USD","value_usd":5380},"fwci":3.9306,"has_fulltext":true,"cited_by_count":90,"citation_normalized_percentile":{"value":0.95784817,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"11","issue":"1","first_page":"5035","last_page":"5035"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10324","display_name":"Microbial bioremediation and biosurfactants","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-omega-dicarboxylic-acids","display_name":"\u03b1,\u03c9-dicarboxylic acids","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cycloalkanes","display_name":"cycloalkanes","score":0.921999990940094},{"id":"https://openalex.org/keywords/cycloalkanols","display_name":"cycloalkanols","score":0.8970000147819519},{"id":"https://openalex.org/keywords/biocatalytic-cascade","display_name":"biocatalytic cascade","score":0.8930000066757202},{"id":"https://openalex.org/keywords/biotransformation","display_name":"biotransformation","score":0.7269999980926514},{"id":"https://openalex.org/keywords/one-pot-biocatalysis","display_name":"one-pot biocatalysis","score":0.7390000224113464},{"id":"https://openalex.org/keywords/aliphatic-dicarboxylic-acids","display_name":"aliphatic dicarboxylic acids","score":0.8330000042915344}],"concepts":[{"id":"https://openalex.org/C27881333","wikidata":"https://www.wikidata.org/wiki/Q864895","display_name":"Biotransformation","level":3,"score":0.7897869348526001},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.7156099677085876},{"id":"https://openalex.org/C191503008","wikidata":"https://www.wikidata.org/wiki/Q16007026","display_name":"Biocatalysis","level":4,"score":0.6419115662574768},{"id":"https://openalex.org/C55904794","wikidata":"https://www.wikidata.org/wiki/Q82682","display_name":"Redox","level":2,"score":0.5876383185386658},{"id":"https://openalex.org/C197957613","wikidata":"https://www.wikidata.org/wiki/Q407280","display_name":"Cofactor","level":3,"score":0.4794713258743286},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4792592525482178},{"id":"https://openalex.org/C171534860","wikidata":"https://www.wikidata.org/wiki/Q655870","display_name":"Environmentally friendly","level":2,"score":0.4525222182273865},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4406389594078064},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4124903976917267},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.38358110189437866},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34369659423828125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2548047602176666},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.15163174271583557},{"id":"https://openalex.org/C65024703","wikidata":"https://www.wikidata.org/wiki/Q373406","display_name":"Reaction mechanism","level":3,"score":0.13331544399261475},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001711","descriptor_name":"Biotransformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003516","descriptor_name":"Cycloparaffins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003998","descriptor_name":"Dicarboxylic Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007218","descriptor_name":"Industrial Microbiology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055162","descriptor_name":"Biocatalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059013","descriptor_name":"Microbial Consortia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060847","descriptor_name":"Metabolic Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41467-020-18833-7","doi":"https://doi.org/10.1038/s41467-020-18833-7","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-020-18833-7","pdf_url":"https://www.nature.com/articles/s41467-020-18833-7.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmid:33028823","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33028823","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7542165","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7542165/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-18833-7","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-020-18833-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:1d9a5decd7184485b2f19344448a1971","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1d9a5decd7184485b2f19344448a1971","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-020-18833-7","doi":"https://doi.org/10.1038/s41467-020-18833-7","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-020-18833-7","pdf_url":"https://www.nature.com/articles/s41467-020-18833-7.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.833299994468689,"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1623092401","display_name":null,"funder_award_id":"2019YFA09005000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3164100085","display_name":null,"funder_award_id":"21702052","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5528303900","display_name":"\u65b0\u578bP450\u753e\u4f53\u7f9f\u5316\u9176\u7684\u5206\u5b50\u8c03\u63a7\u673a\u5236\u53ca\u5176\u7406\u6027\u6539\u9020","funder_award_id":"21977026","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G574376156","display_name":null,"funder_award_id":"2019YFA09005000","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3092106937.pdf","grobid_xml":"https://content.openalex.org/works/W3092106937.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1951469402","https://openalex.org/W1968336963","https://openalex.org/W1969089930","https://openalex.org/W1975877404","https://openalex.org/W1994269973","https://openalex.org/W1998240064","https://openalex.org/W2017215902","https://openalex.org/W2023567779","https://openalex.org/W2028974656","https://openalex.org/W2042786605","https://openalex.org/W2043949108","https://openalex.org/W2048088234","https://openalex.org/W2049211982","https://openalex.org/W2049626217","https://openalex.org/W2052310860","https://openalex.org/W2056009551","https://openalex.org/W2060510188","https://openalex.org/W2069455029","https://openalex.org/W2081121707","https://openalex.org/W2082356898","https://openalex.org/W2083792840","https://openalex.org/W2101392259","https://openalex.org/W2105064370","https://openalex.org/W2113252636","https://openalex.org/W2118398204","https://openalex.org/W2140949609","https://openalex.org/W2151712731","https://openalex.org/W2199708805","https://openalex.org/W2220091378","https://openalex.org/W2266239956","https://openalex.org/W2318054301","https://openalex.org/W2426604790","https://openalex.org/W2509806303","https://openalex.org/W2566462605","https://openalex.org/W2613083880","https://openalex.org/W2620512046","https://openalex.org/W2754316529","https://openalex.org/W2763180935","https://openalex.org/W2773161628","https://openalex.org/W2794296270","https://openalex.org/W2795582507","https://openalex.org/W2891143935","https://openalex.org/W2902036401","https://openalex.org/W2907185979","https://openalex.org/W2913553075","https://openalex.org/W2923524706","https://openalex.org/W2988093181","https://openalex.org/W2996207411","https://openalex.org/W3001263780","https://openalex.org/W3134179996","https://openalex.org/W4233573785","https://openalex.org/W4234557919","https://openalex.org/W4235647767"],"related_works":["https://openalex.org/W4322007613","https://openalex.org/W4309103033","https://openalex.org/W7164071430","https://openalex.org/W2213256540","https://openalex.org/W4400091031","https://openalex.org/W6991726920","https://openalex.org/W4407642703","https://openalex.org/W2599055056","https://openalex.org/W3094949501","https://openalex.org/W2145174079"],"abstract_inverted_index":{"Aliphatic":[0],"\u03b1,\u03c9-dicarboxylic":[1],"acids":[2],"(DCAs)":[3],"are":[4,11,20,91],"a":[5,67,129],"class":[6],"of":[7,28,50,105,120],"useful":[8],"chemicals":[9],"that":[10,19],"currently":[12],"produced":[13],"by":[14,63],"energy-intensive,":[15],"multistage":[16],"chemical":[17],"oxidations":[18],"hazardous":[21],"to":[22,34,52,93,116,132],"the":[23,26,70,109,133],"environment.":[24],"Therefore,":[25],"development":[27],"environmentally":[29],"friendly,":[30],"safe,":[31],"neutral":[32],"routes":[33],"DCAs":[35,117],"is":[36,73],"important.":[37],"We":[38],"report":[39],"an":[40],"in":[41,66,100],"vivo":[42],"artificially":[43],"designed":[44,103],"biocatalytic":[45,71,126],"cascade":[46],"process":[47,127,136],"for":[48,98,137],"biotransformation":[49],"cycloalkanes":[51,113],"DCAs.":[53,139],"To":[54],"reduce":[55],"protein":[56],"expression":[57,65],"burden":[58],"and":[59,90],"redox":[60],"constraints":[61],"caused":[62],"multi-enzyme":[64],"single":[68],"microbe,":[69],"pathway":[72],"divided":[74],"into":[75],"three":[76],"basic":[77],"Escherichia":[78],"coli":[79,96,107],"cell":[80],"modules.":[81],"The":[82,102],"modules":[83,110],"possess":[84],"either":[85],"redox-neutral":[86],"or":[87,114],"redox-regeneration":[88],"systems":[89],"combined":[92],"form":[94],"E.":[95,106],"consortia":[97,104],"use":[99],"biotransformations.":[101],"containing":[108],"efficiently":[111],"convert":[112],"cycloalkanols":[115],"without":[118],"addition":[119],"exogenous":[121],"coenzymes.":[122],"Thus,":[123],"this":[124],"developed":[125],"provides":[128],"promising":[130],"alternative":[131],"current":[134],"industrial":[135],"manufacturing":[138]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-10-15T00:00:00"}