{"id":"https://openalex.org/W3092003456","doi":"https://doi.org/10.1002/jcp.30092","title":"Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus","display_name":"Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus","publication_year":2020,"publication_date":"2020-10-12","ids":{"openalex":"https://openalex.org/W3092003456","doi":"https://doi.org/10.1002/jcp.30092","mag":"3092003456","pmid":"https://pubmed.ncbi.nlm.nih.gov/33044017"},"language":"en","primary_location":{"id":"doi:10.1002/jcp.30092","doi":"https://doi.org/10.1002/jcp.30092","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcp.30092","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcp.30092","source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcp.30092","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034120148","display_name":"Dasiel O. Borroto\u2010Escuela","orcid":"https://orcid.org/0000-0002-5736-373X","observed_orcids":["https://orcid.org/0000-0002-5736-373X"]},"institutions":[{"id":"https://openalex.org/I190397597","display_name":"University of Urbino","ror":"https://ror.org/04q4kt073","country_code":"IT","type":"education","lineage":["https://openalex.org/I190397597"]},{"id":"https://openalex.org/I2802407485","display_name":"Cuban Neuroscience Center","ror":"https://ror.org/00rk1k743","country_code":"CU","type":"facility","lineage":["https://openalex.org/I2802407485"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["CU","IT","SE"],"is_corresponding":false,"raw_author_name":"Dasiel O. Borroto\u2010Escuela","raw_affiliation_strings":["Department of Biomolecular Science, Section of Physiology University of Urbino Urbino Italy","Department of Neuroscience Karolinska Institute Stockholm Sweden","Grupo Boh\u00edo\u2010Estudio Observatorio Cubano de Neurociencias  Yaguajay Cuba"],"raw_orcid":"https://orcid.org/0000-0002-5736-373X","affiliations":[{"raw_affiliation_string":"Department of Biomolecular Science, Section of Physiology University of Urbino Urbino Italy","institution_ids":["https://openalex.org/I190397597"]},{"raw_affiliation_string":"Department of Neuroscience Karolinska Institute Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Grupo Boh\u00edo\u2010Estudio Observatorio Cubano de Neurociencias  Yaguajay Cuba","institution_ids":["https://openalex.org/I2802407485"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053147353","display_name":"Mariana Pita-Rodr\u00edguez","orcid":"https://orcid.org/0000-0002-0717-0518","observed_orcids":["https://orcid.org/0000-0002-0717-0518"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210111385","display_name":"Instituto de Neurologia Y Neurocirugia","ror":"https://ror.org/01c5r7j06","country_code":"CU","type":"facility","lineage":["https://openalex.org/I4210111385"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["CU","ES","SE"],"is_corresponding":false,"raw_author_name":"Mariana Pita\u2010Rodriguez","raw_affiliation_strings":["Departamento de Neurogen\u00e9tica Instituto de Neurolog\u00eda y Neurocirug\u00eda  La Habana Cuba","Department of Neuroscience Karolinska Institute Stockholm Sweden","Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Neurogen\u00e9tica Instituto de Neurolog\u00eda y Neurocirug\u00eda  La Habana Cuba","institution_ids":["https://openalex.org/I4210111385"]},{"raw_affiliation_string":"Department of Neuroscience Karolinska Institute Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain","institution_ids":["https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019645561","display_name":"Ram\u00f3n Fores\u2010Pons","orcid":"https://orcid.org/0000-0002-0198-7260","observed_orcids":["https://orcid.org/0000-0002-0198-7260"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES","SE"],"is_corresponding":false,"raw_author_name":"Ram\u00f3n Fores\u2010Pons","raw_affiliation_strings":["Department of Neuroscience Karolinska Institute Stockholm Sweden","Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience Karolinska Institute Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain","institution_ids":["https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013881020","display_name":"Miguel \u00c1ngel Barbancho","orcid":"https://orcid.org/0000-0001-9120-4831","observed_orcids":["https://orcid.org/0000-0001-9120-4831"]},"institutions":[{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Miguel A. Barbancho","raw_affiliation_strings":["Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain"],"raw_orcid":"https://orcid.org/0000-0001-9120-4831","affiliations":[{"raw_affiliation_string":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain","institution_ids":["https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048458525","display_name":"Kjell Fux\u00e9","orcid":"https://orcid.org/0000-0001-8491-4288","observed_orcids":["https://orcid.org/0000-0001-8491-4288"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Kjell Fuxe","raw_affiliation_strings":["Department of Neuroscience Karolinska Institute Stockholm Sweden"],"raw_orcid":"https://orcid.org/0000-0001-8491-4288","affiliations":[{"raw_affiliation_string":"Department of Neuroscience Karolinska Institute Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020373627","display_name":"Manuel Narv\u00e1ez","orcid":"https://orcid.org/0000-0003-0922-4900","observed_orcids":["https://orcid.org/0000-0003-0922-4900"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES","SE"],"is_corresponding":true,"raw_author_name":"Manuel Narv\u00e1ez","raw_affiliation_strings":["Department of Neuroscience Karolinska Institute Stockholm Sweden","Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain"],"raw_orcid":"https://orcid.org/0000-0003-0922-4900","affiliations":[{"raw_affiliation_string":"Department of Neuroscience Karolinska Institute Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga, Facultad de Medicina Universidad de M\u00e1laga  M\u00e1laga Spain","institution_ids":["https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5020373627"],"corresponding_institution_ids":["https://openalex.org/I28166907","https://openalex.org/I4210164724","https://openalex.org/I82767444"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.7561,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.60937903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"236","issue":"5","first_page":"3565","last_page":"3578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galr2","display_name":"galanin receptor 2","score":0.9150000214576721},{"id":"https://openalex.org/keywords/y1-receptor","display_name":"Y1 receptor","score":0.9800000190734863},{"id":"https://openalex.org/keywords/heteroreceptor-complexes","display_name":"heteroreceptor complexes","score":0.7440000176429749},{"id":"https://openalex.org/keywords/antidepressant-effects","display_name":"antidepressant effects","score":0.7990000247955322},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.718999981880188},{"id":"https://openalex.org/keywords/ventral-hippocampus","display_name":"ventral hippocampus","score":0.8410000205039978},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9940000176429749},{"id":"https://openalex.org/keywords/neural-precursors","display_name":"neuronal precursors","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7020000219345093},{"id":"https://openalex.org/keywords/erk-signaling","display_name":"ERK signaling","score":0.8309999704360962},{"id":"https://openalex.org/keywords/doublecortin","display_name":"doublecortin","score":0.7260000109672546},{"id":"https://openalex.org/keywords/forced-swim-test","display_name":"forced swim test","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.8533772230148315},{"id":"https://openalex.org/C19519825","wikidata":"https://www.wikidata.org/wiki/Q417867","display_name":"Galanin","level":4,"score":0.7908569574356079},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5824873447418213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5476568341255188},{"id":"https://openalex.org/C36076068","wikidata":"https://www.wikidata.org/wiki/Q5517939","display_name":"Galanin receptor","level":5,"score":0.5325469374656677},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5133358836174011},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.5007843971252441},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.49097874760627747},{"id":"https://openalex.org/C2780451725","wikidata":"https://www.wikidata.org/wiki/Q4867818","display_name":"Basolateral amygdala","level":3,"score":0.4550895690917969},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38315388560295105},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.35129085183143616},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33619165420532227},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.30586111545562744},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.22956860065460205},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08847078680992126},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06900352239608765}],"mesh":[{"descriptor_ui":"D000089622","descriptor_name":"Doublecortin Domain Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000089662","descriptor_name":"Doublecortin Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001973","descriptor_name":"Bromodeoxyuridine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008869","descriptor_name":"Microtubule-Associated Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009478","descriptor_name":"Neuropeptide Y","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013550","descriptor_name":"Swimming","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017476","descriptor_name":"Receptors, Neuropeptide Y","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017476","descriptor_name":"Receptors, Neuropeptide Y","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019004","descriptor_name":"Galanin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020935","descriptor_name":"MAP Kinase Signaling System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027602","descriptor_name":"Serum Response Element","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044092","descriptor_name":"Receptor, Galanin, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058953","descriptor_name":"Neural Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/jcp.30092","doi":"https://doi.org/10.1002/jcp.30092","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcp.30092","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcp.30092","source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},{"id":"pmid:33044017","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33044017","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cellular physiology","raw_type":"Journal Article"},{"id":"pmh:oai:riuma.uma.es:10630/36932","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcp.30092","pdf_url":null,"source":{"id":"https://openalex.org/S4306401385","display_name":"Repositorio Institucional de la Universidad de M\u00e1laga (University of M\u00e1laga)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I82767444","host_organization_name":"Universidad de M\u00e1laga","host_organization_lineage":["https://openalex.org/I82767444"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nd","license_id":"https://openalex.org/licenses/cc-by-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1002/jcp.30092","doi":"https://doi.org/10.1002/jcp.30092","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jcp.30092","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcp.30092","source":{"id":"https://openalex.org/S43643205","display_name":"Journal of Cellular Physiology","issn_l":"0021-9541","issn":["0021-9541","1097-4652"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cellular Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1166441300","display_name":null,"funder_award_id":"F02018-0286","funder_id":"https://openalex.org/F4320322168","funder_display_name":"Hj\u00e4rnfonden"},{"id":"https://openalex.org/G275093274","display_name":null,"funder_award_id":"F02019-0296","funder_id":"https://openalex.org/F4320322168","funder_display_name":"Hj\u00e4rnfonden"},{"id":"https://openalex.org/G3291463918","display_name":null,"funder_award_id":"62X-00715-50-3","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3891841828","display_name":null,"funder_award_id":"UMA18\u2010FEDERJA\u2010100","funder_id":"https://openalex.org/F4320311265","funder_display_name":"Universidad de M\u00e1laga"},{"id":"https://openalex.org/G4283602194","display_name":null,"funder_award_id":"62X-00715-50-3","funder_id":"https://openalex.org/F4320323764","funder_display_name":"Medicinska Forskningsr\u00e5det"},{"id":"https://openalex.org/G4311997634","display_name":null,"funder_award_id":"62X-00715-50-3","funder_id":"https://openalex.org/F4320322168","funder_display_name":"Hj\u00e4rnfonden"}],"funders":[{"id":"https://openalex.org/F4320311265","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28"},{"id":"https://openalex.org/F4320322168","display_name":"Hj\u00e4rnfonden","ror":"https://ror.org/014btj409"},{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320323764","display_name":"Medicinska Forskningsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3092003456.pdf","grobid_xml":"https://content.openalex.org/works/W3092003456.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W1553219548","https://openalex.org/W1591013905","https://openalex.org/W1751249310","https://openalex.org/W1806803216","https://openalex.org/W1933745278","https://openalex.org/W1974650724","https://openalex.org/W1977184712","https://openalex.org/W1981734883","https://openalex.org/W1987212298","https://openalex.org/W1987239750","https://openalex.org/W1991192535","https://openalex.org/W1995953759","https://openalex.org/W1996166611","https://openalex.org/W1998957724","https://openalex.org/W2006751457","https://openalex.org/W2014192652","https://openalex.org/W2016176125","https://openalex.org/W2019325496","https://openalex.org/W2025872894","https://openalex.org/W2030582237","https://openalex.org/W2035203095","https://openalex.org/W2035422298","https://openalex.org/W2047507533","https://openalex.org/W2051005796","https://openalex.org/W2054145123","https://openalex.org/W2059746752","https://openalex.org/W2064715357","https://openalex.org/W2065822983","https://openalex.org/W2067856703","https://openalex.org/W2071287117","https://openalex.org/W2072993035","https://openalex.org/W2079311820","https://openalex.org/W2086066124","https://openalex.org/W2089299823","https://openalex.org/W2103255996","https://openalex.org/W2112758538","https://openalex.org/W2115290127","https://openalex.org/W2129994609","https://openalex.org/W2134389527","https://openalex.org/W2136863044","https://openalex.org/W2147497112","https://openalex.org/W2163815564","https://openalex.org/W2169945211","https://openalex.org/W2183068406","https://openalex.org/W2197770666","https://openalex.org/W2497275630","https://openalex.org/W2579967741","https://openalex.org/W2748742210","https://openalex.org/W2789329186","https://openalex.org/W2796418566","https://openalex.org/W2801067720","https://openalex.org/W2801769333","https://openalex.org/W2802269477","https://openalex.org/W2802439408","https://openalex.org/W2893696361","https://openalex.org/W2925056974","https://openalex.org/W2963007925","https://openalex.org/W2990512746","https://openalex.org/W3013824813","https://openalex.org/W4252911236"],"related_works":["https://openalex.org/W2197770666","https://openalex.org/W6981941388","https://openalex.org/W7047188818","https://openalex.org/W7028612725","https://openalex.org/W4299416765","https://openalex.org/W7038694964","https://openalex.org/W4313495071","https://openalex.org/W7064263471","https://openalex.org/W4393949189","https://openalex.org/W7057419573"],"abstract_inverted_index":{"A":[0],"need":[1],"for":[2,210,221,245],"new":[3],"antidepressants":[4,9],"is":[5],"necessary":[6],"since":[7],"traditional":[8],"have":[10],"several":[11,26],"flaws.":[12],"Neuropeptide":[13],"Y(NPY)":[14],"Y1":[15],"receptor":[16,21],"(NPYY1R)":[17],"and":[18,45,85,96,105,158],"galanin":[19],"(GAL)":[20],"2":[22],"(GALR2)":[23],"interact":[24],"in":[25,69,99,109,113,124,137,160,183,232,241],"regions":[27],"of":[28,52,62,83,88,131,143,156,172,192,201,224,237,249],"the":[29,33,39,50,59,63,80,86,89,114,125,144,148,154,166,170,178,184,208,211,219,222,233,238,242,246],"limbic":[30],"system,":[31],"including":[32],"hippocampus.":[34,186],"The":[35],"current":[36],"study":[37],"assesses":[38],"antidepressant":[40,111,212],"effects":[41,168],"induced":[42],"by":[43,199],"GALR2":[44,84,95,104,145,157,175],"NPYY1R":[46,97,106,159],"coactivation,":[47],"together":[48],"with":[49],"evaluation":[51],"cell":[53,100,122,161,193],"proliferation":[54,123,194],"through":[55],"5-Bromo-2'-deoxyuridine":[56],"expression":[57,81,146],"within":[58],"dentate":[60,239],"gyrus":[61,240],"ventral":[64,185,243],"hippocampus":[65,244],"(vDG).":[66],"We":[67],"employed":[68],"situ":[70],"proximity":[71],"ligation":[72],"assay":[73],"to":[74,120,147,165],"manifest":[75],"GALR2/NPYY1R":[76,132,179,229],"heteroreceptor":[77,133,180],"complexes.":[78],"Additionally,":[79],"pattern":[82],"activation":[87,171],"extracellular-regulated":[90],"kinases":[91],"(ERK)":[92],"pathway":[93],"after":[94,116],"costimulation":[98],"cultures":[101],"were":[102],"examined.":[103],"coactivation":[107,155],"resulted":[108],"sustained":[110],"behaviors":[112],"FST":[115],"24":[117],"h,":[118],"linked":[119],"increased":[121,129],"vDG.":[126],"Moreover,":[127],"an":[128],"density":[130],"complexes":[134,181],"was":[135,151],"observed":[136,152],"vDG,":[138],"on":[139,169],"doublecortin-expressing":[140],"neuroblasts.":[141],"Recruitment":[142],"plasma":[149],"membrane":[150],"upon":[153],"cultures,":[162],"presumably":[163],"associated":[164],"enhanced":[167],"ERK":[173,202],"pathway.":[174,203],"may":[176,188,206,217],"promote":[177],"formation":[182],"It":[187],"induce":[189],"a":[190,196],"transformation":[191],"toward":[195],"neuronal":[197,234],"lineage":[198],"enhancement":[200],"Thus,":[204],"it":[205],"give":[207],"mechanism":[209],"behavior":[213],"observed.":[214],"These":[215],"results":[216],"provide":[218],"basis":[220],"development":[223],"heterobivalent":[225],"agonist":[226],"pharmacophores,":[227],"targeting":[228],"heteromers,":[230],"especially":[231],"precursor":[235],"cells":[236],"novel":[247],"treatment":[248],"depression.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-10-15T00:00:00"}