{"id":"https://openalex.org/W3091968014","doi":"https://doi.org/10.1063/5.0023101","title":"Synthesis, characterization and antioxidant studies of benzo[4, 5]imidazo[2, 1-b]thiazole derivatives","display_name":"Synthesis, characterization and antioxidant studies of benzo[4, 5]imidazo[2, 1-b]thiazole derivatives","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3091968014","doi":"https://doi.org/10.1063/5.0023101","mag":"3091968014"},"language":"en","primary_location":{"id":"doi:10.1063/5.0023101","doi":"https://doi.org/10.1063/5.0023101","is_oa":false,"landing_page_url":"https://doi.org/10.1063/5.0023101","pdf_url":null,"source":{"id":"https://openalex.org/S2764696622","display_name":"AIP conference proceedings","issn_l":"0094-243X","issn":["0094-243X","1551-7616","1935-0465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIP Conference Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042775973","display_name":"G. R. Nikhila","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I302410947","display_name":"M S Ramaiah University of Applied Sciences","ror":"https://ror.org/02anh8x74","country_code":"IN","type":"education","lineage":["https://openalex.org/I302410947"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"G. R. Nikhila","raw_affiliation_strings":["Department of Chemistry, M.S. Ramaiah University of Applied Sciences, No. 470P, IV Phase, Peenya Industrial Area, Bangalore, Karnataka -560058, INDIA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, M.S. Ramaiah University of Applied Sciences, No. 470P, IV Phase, Peenya Industrial Area, Bangalore, Karnataka -560058, INDIA","institution_ids":["https://openalex.org/I302410947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062275858","display_name":"Sheetal Batakurki","orcid":"https://orcid.org/0000-0001-6363-173X","observed_orcids":["https://orcid.org/0000-0001-6363-173X"]},"institutions":[{"id":"https://openalex.org/I302410947","display_name":"M S Ramaiah University of Applied Sciences","ror":"https://ror.org/02anh8x74","country_code":"IN","type":"education","lineage":["https://openalex.org/I302410947"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"S. R. Batakurki","raw_affiliation_strings":["Department of Chemistry, M.S. Ramaiah University of Applied Sciences, No. 470P, IV Phase, Peenya Industrial Area, Bangalore, Karnataka -560058, INDIA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, M.S. Ramaiah University of Applied Sciences, No. 470P, IV Phase, Peenya Industrial Area, Bangalore, Karnataka -560058, INDIA","institution_ids":["https://openalex.org/I302410947"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086761602","display_name":"Basappa C. Yallur","orcid":"https://orcid.org/0000-0002-9099-7056","observed_orcids":["https://orcid.org/0000-0002-9099-7056"]},"institutions":[{"id":"https://openalex.org/I4405255153","display_name":"Ramaiah Institute of Technology","ror":"https://ror.org/02nyr4y94","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405255153"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"B. C. Yallur","raw_affiliation_strings":["Department of Chemistry, M.S. Ramaiah Institute Of Technology, MSRIT Post, M S Ramaiah Nagar, Bangalore, Karnataka - 560054, INDIA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, M.S. Ramaiah Institute Of Technology, MSRIT Post, M S Ramaiah Nagar, Bangalore, Karnataka - 560054, INDIA","institution_ids":["https://openalex.org/I4405255153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5062275858"],"corresponding_institution_ids":["https://openalex.org/I302410947"],"apc_list":null,"apc_paid":null,"fwci":4.2308,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.90690209,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"2274","issue":null,"first_page":"050017","last_page":"050017"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.9384999871253967,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.9384999871253967,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14459","display_name":"Synthesis and Reactions of Organic Compounds","score":0.017899999395012856,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schiff-base","display_name":"Schiff base","score":0.8830000162124634},{"id":"https://openalex.org/keywords/2-mercaptobenzimidazole","display_name":"2-mercaptobenzimidazole","score":0.8029999732971191},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.8130000233650208},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9739999771118164},{"id":"https://openalex.org/keywords/dpph-radical-scavenging-activity","display_name":"DPPH radical scavenging","score":0.9800000190734863}],"concepts":[{"id":"https://openalex.org/C2778464347","wikidata":"https://www.wikidata.org/wiki/Q413426","display_name":"Thiazole","level":2,"score":0.9446887969970703},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8479316234588623},{"id":"https://openalex.org/C2776428424","wikidata":"https://www.wikidata.org/wiki/Q2602701","display_name":"Schiff base","level":2,"score":0.5325357913970947},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.5162687301635742},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.48033371567726135},{"id":"https://openalex.org/C207245611","wikidata":"https://www.wikidata.org/wiki/Q910058","display_name":"Condensation reaction","level":3,"score":0.46717318892478943},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4520662724971771},{"id":"https://openalex.org/C517835270","wikidata":"https://www.wikidata.org/wiki/Q879","display_name":"Bromine","level":2,"score":0.4182731509208679},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3959459066390991},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3435116112232208},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.11825811862945557}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1063/5.0023101","doi":"https://doi.org/10.1063/5.0023101","is_oa":false,"landing_page_url":"https://doi.org/10.1063/5.0023101","pdf_url":null,"source":{"id":"https://openalex.org/S2764696622","display_name":"AIP conference proceedings","issn_l":"0094-243X","issn":["0094-243X","1551-7616","1935-0465"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIP Conference Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1452825290","https://openalex.org/W1972391291","https://openalex.org/W1987019476","https://openalex.org/W2146002095","https://openalex.org/W2564904760","https://openalex.org/W2596167185","https://openalex.org/W2605254180","https://openalex.org/W2811017747","https://openalex.org/W2951631204"],"related_works":["https://openalex.org/W2088185537","https://openalex.org/W2889211350","https://openalex.org/W4410001053","https://openalex.org/W2782641997","https://openalex.org/W2791295229","https://openalex.org/W2614074825","https://openalex.org/W3009836913","https://openalex.org/W4405239087","https://openalex.org/W2593964812","https://openalex.org/W4231215953"],"abstract_inverted_index":{"Heterocyclic":[0],"compounds":[1,87,109],"and":[2,32,55,66,98],"their":[3,12,36,114],"derivatives":[4],"are":[5],"prominent":[6],"molecules":[7],"in":[8],"pharmaceutical":[9],"industries":[10],"for":[11,48,103,113,127,138,154],"various":[13,17],"medicinal":[14],"properties.":[15],"Among":[16,141],"heterocyclic":[18],"moieties":[19],"benzo[4,":[20,81],"5]imidazo[2,":[21,82,122],"1-b]thiazole":[22],"has":[23],"gained":[24],"lot":[25],"of":[26,28,51,70,80],"interest":[27],"synthetic":[29,46],"organic":[30],"chemist":[31],"biologist":[33],"due":[34],"to":[35,132],"potent":[37],"pharmacological":[38],"activities.":[39],"The":[40,106],"present":[41],"work":[42],"involves":[43],"an":[44],"efficient":[45],"route":[47],"the":[49,85,142],"synthesis":[50,63],"Bromomalonaldehyde":[52,65],"from":[53,64],"1,1,3,3,-tetromethoxypropane":[54],"bromine":[56],"under":[57],"mild":[58],"conditions.":[59],"Further":[60,68],"2-mercaptobenzimidazole":[61,71],"carbaldehyde":[62,72],"2-marcaptobenzimidazole.":[67],"condensation":[69],"with":[73],"primary":[74],"amines":[75],"yields":[76],"novel":[77],"Schiff":[78,144],"base":[79],"1-b]thiazole.":[83],"All":[84],"synthesized":[86,108],"have":[88,110],"been":[89,111],"supported":[90],"by":[91,117],"infra-red":[92],"spectroscopy,":[93],"1H":[94],"nuclear":[95],"magnetic":[96],"spectrum":[97],"LC-M":[99],"S":[100],"spectral":[101],"data":[102],"structural":[104],"confirmation.":[105],"newly":[107],"screened":[112],"antioxidant":[115],"studies":[116],"DPPH":[118],"method.":[119],"Compound":[120],"Benzo[4,":[121],"1-b]thiazole-2-carbaldehyde":[123],"showed":[124,135,151],"95%":[125],"inhibiton":[126],"500":[128,139],"\u00b5g/lit":[129],"when":[130],"compared":[131],"7-Nitrobenzo[4,5]imidazo[2,1-b]thiazole-2-carbaldehyde":[133],"which":[134],"85%":[136],"inhibton":[137],"\u00b5g/ml.":[140,156],"sythesised":[143],"bases,":[145],"compound":[146],"1-(benzo[4,5]imida":[147],"zole[2,1-b]thia":[148],"zole-2-yl)-N":[149],"-(4-nitrophenyl)methanimine":[150],"97.5%":[152],"inhibition":[153],"800":[155]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-10-15T00:00:00"}