{"id":"https://openalex.org/W3091879012","doi":"https://doi.org/10.1128/iai.00542-20","title":"Role of metAB in Methionine Metabolism and Optimal Chicken Colonization in Campylobacter jejuni","display_name":"Role of metAB in Methionine Metabolism and Optimal Chicken Colonization in Campylobacter jejuni","publication_year":2020,"publication_date":"2020-10-08","ids":{"openalex":"https://openalex.org/W3091879012","doi":"https://doi.org/10.1128/iai.00542-20","mag":"3091879012","pmid":"https://pubmed.ncbi.nlm.nih.gov/33046508","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7927925"},"language":"en","primary_location":{"id":"doi:10.1128/iai.00542-20","doi":"https://doi.org/10.1128/iai.00542-20","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00542-20","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7927925","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090969224","display_name":"Brandon Ruddell","orcid":"https://orcid.org/0000-0002-5413-2346","observed_orcids":["https://orcid.org/0000-0002-5413-2346"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon Ruddell","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015830857","display_name":"Alan Hassall","orcid":"https://orcid.org/0009-0008-9042-147X","observed_orcids":["https://orcid.org/0009-0008-9042-147X"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan Hassall","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025498781","display_name":"Orhan \u015eahin","orcid":"https://orcid.org/0000-0003-0262-4581","observed_orcids":["https://orcid.org/0000-0003-0262-4581"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Orhan Sahin","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086172106","display_name":"Qijing Zhang","orcid":"https://orcid.org/0009-0005-8690-1655","observed_orcids":["https://orcid.org/0009-0005-8690-1655"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qijing Zhang","raw_affiliation_strings":["Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027984887","display_name":"Paul Joseph Plummer","orcid":"https://orcid.org/0000-0002-5784-8382","observed_orcids":["https://orcid.org/0000-0002-5784-8382"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul J. Plummer","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017892491","display_name":"Amanda Jo Kreuder","orcid":"https://orcid.org/0000-0002-3982-8660","observed_orcids":["https://orcid.org/0000-0002-3982-8660"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda J. Kreuder","raw_affiliation_strings":["Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA"],"raw_orcid":"https://orcid.org/0000-0002-3982-8660","affiliations":[{"raw_affiliation_string":"Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA","institution_ids":["https://openalex.org/I173911158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I173911158"],"apc_list":null,"apc_paid":null,"fwci":0.648,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.70409051,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"89","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10486","display_name":"Salmonella and Campylobacter epidemiology","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/campylobacter-jejuni","display_name":"Campylobacter jejuni","score":0.9829999804496765},{"id":"https://openalex.org/keywords/methionine-metabolism","display_name":"methionine metabolism","score":0.984000027179718},{"id":"https://openalex.org/keywords/chicken-colonization","display_name":"chicken colonization","score":0.878000020980835},{"id":"https://openalex.org/keywords/luxs","display_name":"LuxS","score":0.7409999966621399},{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9739999771118164},{"id":"https://openalex.org/keywords/methionine-biosynthesis","display_name":"methionine biosynthesis","score":0.800000011920929},{"id":"https://openalex.org/keywords/zoonotic-pathogens","display_name":"zoonotic pathogens","score":0.7360000014305115},{"id":"https://openalex.org/keywords/gastrointestinal-colonization","display_name":"intestinal colonization","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C2776957140","wikidata":"https://www.wikidata.org/wiki/Q265488","display_name":"Campylobacter jejuni","level":3,"score":0.7755930423736572},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7268974781036377},{"id":"https://openalex.org/C2780912031","wikidata":"https://www.wikidata.org/wiki/Q180341","display_name":"Methionine","level":3,"score":0.6884894371032715},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5514423251152039},{"id":"https://openalex.org/C2779910956","wikidata":"https://www.wikidata.org/wiki/Q131488","display_name":"Campylobacter","level":3,"score":0.5408045053482056},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5071115493774414},{"id":"https://openalex.org/C2779840497","wikidata":"https://www.wikidata.org/wiki/Q418214","display_name":"Homoserine","level":5,"score":0.41479143500328064},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2572975158691406},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25338369607925415},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22593674063682556},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.19160038232803345},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.1685713827610016},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.1074155867099762},{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.08397665619850159}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008715","descriptor_name":"Methionine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011201","descriptor_name":"Poultry Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016123","descriptor_name":"Campylobacter jejuni","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/iai.00542-20","doi":"https://doi.org/10.1128/iai.00542-20","is_oa":false,"landing_page_url":"https://doi.org/10.1128/iai.00542-20","pdf_url":null,"source":{"id":"https://openalex.org/S128227336","display_name":"Infection and Immunity","issn_l":"0019-9567","issn":["0019-9567","1070-6313","1098-5522"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and Immunity","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7927925","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7927925","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},{"id":"pmid:33046508","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33046508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection and immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7927925","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7927925","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infect Immun","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311090","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W1515951856","https://openalex.org/W1529777488","https://openalex.org/W1849301422","https://openalex.org/W1867554764","https://openalex.org/W1963626859","https://openalex.org/W1964184380","https://openalex.org/W1971439989","https://openalex.org/W1972435034","https://openalex.org/W1973979523","https://openalex.org/W1986787331","https://openalex.org/W1991941799","https://openalex.org/W1995370257","https://openalex.org/W1996518446","https://openalex.org/W1998953205","https://openalex.org/W2005032760","https://openalex.org/W2005046889","https://openalex.org/W2005874691","https://openalex.org/W2011059895","https://openalex.org/W2025932672","https://openalex.org/W2030588200","https://openalex.org/W2046899957","https://openalex.org/W2048227696","https://openalex.org/W2058305781","https://openalex.org/W2058776820","https://openalex.org/W2069228394","https://openalex.org/W2074014006","https://openalex.org/W2074045262","https://openalex.org/W2090257187","https://openalex.org/W2103540045","https://openalex.org/W2104293843","https://openalex.org/W2104400833","https://openalex.org/W2106074866","https://openalex.org/W2107277218","https://openalex.org/W2107975574","https://openalex.org/W2108969636","https://openalex.org/W2110953168","https://openalex.org/W2113422317","https://openalex.org/W2119217447","https://openalex.org/W2122918147","https://openalex.org/W2123022819","https://openalex.org/W2126286475","https://openalex.org/W2127028391","https://openalex.org/W2127347791","https://openalex.org/W2127639177","https://openalex.org/W2132815440","https://openalex.org/W2138593217","https://openalex.org/W2141445066","https://openalex.org/W2144111851","https://openalex.org/W2150180261","https://openalex.org/W2152495803","https://openalex.org/W2153255335","https://openalex.org/W2155777323","https://openalex.org/W2157811187","https://openalex.org/W2162203023","https://openalex.org/W2167178110","https://openalex.org/W2171939089","https://openalex.org/W2191779450","https://openalex.org/W2417159482","https://openalex.org/W2474723803","https://openalex.org/W2519078499","https://openalex.org/W2601343332","https://openalex.org/W2605287328","https://openalex.org/W2616355258","https://openalex.org/W2793079821","https://openalex.org/W2802172982","https://openalex.org/W2809500310","https://openalex.org/W2895850079","https://openalex.org/W2920477679","https://openalex.org/W2999241145","https://openalex.org/W3022953558"],"related_works":["https://openalex.org/W2519783234","https://openalex.org/W7098177572","https://openalex.org/W4406154476","https://openalex.org/W4318753752","https://openalex.org/W2474723803","https://openalex.org/W2058776820","https://openalex.org/W7135868792","https://openalex.org/W2110953168","https://openalex.org/W2030588200","https://openalex.org/W2317093575"],"abstract_inverted_index":{"Campylobacter":[0],"jejuni":[1,18,31],"is":[2,7,26,57],"a":[3],"zoonotic":[4],"pathogen":[5],"and":[6,64],"one":[8],"of":[9,13,21,34,47,50],"the":[10,22,45,60],"leading":[11],"causes":[12],"human":[14],"gastroenteritis":[15],"worldwide.":[16],"C.":[17,30],"IA3902":[19],"(representative":[20,33],"sheep":[23],"abortion":[24],"clone)":[25],"genetically":[27],"similar":[28],"to":[29,53,69],"W7":[32],"strain":[35],"type":[36],"NCTC":[37],"11168);":[38],"however,":[39],"there":[40],"are":[41],"significant":[42],"differences":[43],"in":[44],"ability":[46],"luxS":[48],"mutants":[49],"these":[51],"strains":[52],"colonize":[54],"chickens.":[55],"LuxS":[56],"essential":[58],"for":[59,67],"activated":[61],"methyl":[62],"cycle":[63],"generates":[65],"homocysteine":[66],"conversion":[68],"l":[70],"-methionine.":[71]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2020-10-15T00:00:00"}