{"id":"https://openalex.org/W3090950993","doi":"https://doi.org/10.1073/pnas.2001749117","title":"Dynamic evolution of great ape Y chromosomes","display_name":"Dynamic evolution of great ape Y chromosomes","publication_year":2020,"publication_date":"2020-10-05","ids":{"openalex":"https://openalex.org/W3090950993","doi":"https://doi.org/10.1073/pnas.2001749117","mag":"3090950993","pmid":"https://pubmed.ncbi.nlm.nih.gov/33020265","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7585023"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.2001749117","doi":"https://doi.org/10.1073/pnas.2001749117","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2001749117","pdf_url":"https://www.pnas.org/content/pnas/117/42/26273.full.pdf","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.pnas.org/content/pnas/117/42/26273.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067616652","display_name":"Monika \u010cechov\u00e1","orcid":"https://orcid.org/0000-0002-7420-2663","observed_orcids":["https://orcid.org/0000-0002-7420-2663"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monika Cechova","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;"],"raw_orcid":"https://orcid.org/0000-0002-7420-2663","affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061091881","display_name":"Rahulsimham Vegesna","orcid":"https://orcid.org/0000-0001-9829-9765","observed_orcids":["https://orcid.org/0000-0001-9829-9765"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rahulsimham Vegesna","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;","Intercollege Graduate Program in Bioinformatics and Genomics, Penn State University, University Park, PA 16802;"],"raw_orcid":"https://orcid.org/0000-0001-9829-9765","affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Intercollege Graduate Program in Bioinformatics and Genomics, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086100584","display_name":"Marta Tomaszkiewicz","orcid":"https://orcid.org/0000-0003-1523-200X","observed_orcids":["https://orcid.org/0000-0003-1523-200X"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marta Tomaszkiewicz","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;"],"raw_orcid":"https://orcid.org/0000-0003-1523-200X","affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Robert S. Harris","orcid":"https://orcid.org/0000-0001-5464-6892","observed_orcids":["https://orcid.org/0000-0001-5464-6892"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S. Harris","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;"],"raw_orcid":"https://orcid.org/0000-0001-5464-6892","affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105670009","display_name":"Di Chen","orcid":"https://orcid.org/0000-0001-6321-5998","observed_orcids":["https://orcid.org/0000-0001-6321-5998"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Di Chen","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063592780","display_name":"Samarth Rangavittal","orcid":"https://orcid.org/0000-0003-0110-4322","observed_orcids":["https://orcid.org/0000-0003-0110-4322"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samarth Rangavittal","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;","Intercollege Graduate Program in Bioinformatics and Genomics, Penn State University, University Park, PA 16802;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Intercollege Graduate Program in Bioinformatics and Genomics, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066909672","display_name":"Paul Medvedev","orcid":"https://orcid.org/0000-0003-3143-594X","observed_orcids":["https://orcid.org/0000-0003-3143-594X"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Paul Medvedev","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Penn State University, University Park, PA 16802","Department of Computer Science and Engineering, Penn State University, University Park, PA 16802;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Penn State University, University Park, PA 16802","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042289737","display_name":"Kateryna D. Makova","orcid":"https://orcid.org/0000-0002-6212-9526","observed_orcids":["https://orcid.org/0000-0002-6212-9526"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kateryna D. Makova","raw_affiliation_strings":["Department of Biology, Penn State University, University Park, PA 16802;"],"raw_orcid":"https://orcid.org/0000-0002-6212-9526","affiliations":[{"raw_affiliation_string":"Department of Biology, Penn State University, University Park, PA 16802;","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042289737","https://openalex.org/A5066909672"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":null,"apc_paid":null,"fwci":3.1765,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.93122441,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"117","issue":"42","first_page":"26273","last_page":"26280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.07779999822378159,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/y-chromosome-evolution","display_name":"Y chromosome evolution","score":0.972000002861023},{"id":"https://openalex.org/keywords/great-apes","display_name":"great apes","score":0.9909999966621399},{"id":"https://openalex.org/keywords/repetitive-dna","display_name":"repetitive DNA","score":0.718999981880188},{"id":"https://openalex.org/keywords/multi-copy-genes","display_name":"multi-copy genes","score":0.8489999771118164},{"id":"https://openalex.org/keywords/sperm-competition","display_name":"sperm competition","score":0.8669999837875366},{"id":"https://openalex.org/keywords/gene-loss","display_name":"gene loss","score":0.8569999933242798},{"id":"https://openalex.org/keywords/gene-regulatory-elements","display_name":"gene regulatory elements","score":0.7080000042915344},{"id":"https://openalex.org/keywords/chimpanzees","display_name":"chimpanzees","score":1.0},{"id":"https://openalex.org/keywords/bonobos","display_name":"bonobos","score":1.0},{"id":"https://openalex.org/keywords/gorillas","display_name":"gorillas","score":0.9990000128746033},{"id":"https://openalex.org/keywords/orangutans","display_name":"orangutans","score":0.9350000023841858},{"id":"https://openalex.org/keywords/threatened-species","display_name":"threatened species","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C2778273743","wikidata":"https://www.wikidata.org/wiki/Q19537","display_name":"Bonobo","level":2,"score":0.9053905010223389},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8255033493041992},{"id":"https://openalex.org/C2777477413","wikidata":"https://www.wikidata.org/wiki/Q36611","display_name":"Gorilla","level":2,"score":0.7432796955108643},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6388854384422302},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6053115725517273},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.4967096447944641},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.47808241844177246},{"id":"https://openalex.org/C2780246931","wikidata":"https://www.wikidata.org/wiki/Q202771","display_name":"Y chromosome","level":3,"score":0.4728826880455017},{"id":"https://openalex.org/C2779987252","wikidata":"https://www.wikidata.org/wiki/Q635162","display_name":"Hominidae","level":3,"score":0.41590696573257446},{"id":"https://openalex.org/C2988562018","wikidata":"https://www.wikidata.org/wiki/Q1063","display_name":"Biological evolution","level":2,"score":0.183248370885849},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002679","descriptor_name":"Pan troglodytes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005785","descriptor_name":"Gene Conversion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006071","descriptor_name":"Gorilla gorilla","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014998","descriptor_name":"Y Chromosome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015186","descriptor_name":"Hominidae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019974","descriptor_name":"Pan paniscus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057079","descriptor_name":"Pongo","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1073/pnas.2001749117","doi":"https://doi.org/10.1073/pnas.2001749117","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2001749117","pdf_url":"https://www.pnas.org/content/pnas/117/42/26273.full.pdf","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"doi:10.1101/2020.01.21.913863","doi":"https://doi.org/10.1101/2020.01.21.913863","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2020.01.21.913863","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2020/01/31/2020.01.21.913863.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:6536236","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7585023","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7585023","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7585023","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:33020265","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33020265","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt9gw1f3fk","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/9gw1f3fk","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 42","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1073/pnas.2001749117","doi":"https://doi.org/10.1073/pnas.2001749117","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.2001749117","pdf_url":"https://www.pnas.org/content/pnas/117/42/26273.full.pdf","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1106789989","display_name":"Y Chromosome Evolution","funder_award_id":"R01GM130691","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G151381017","display_name":null,"funder_award_id":"R01GM130691","funder_id":"https://openalex.org/F4320337544","funder_display_name":"Office of Extramural Research, National Institutes of Health"},{"id":"https://openalex.org/G2039187732","display_name":"ABI Innovation: A Novel Framework for Detecting Genomic Structural Variation","funder_award_id":"1356529","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3926047959","display_name":"XPS: FULL: DSD: End-to-end Acceleration of Genomic Workflows on Emerging Heterogeneous Supercomputers","funder_award_id":"1439057","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G4106800444","display_name":"CAREER: De Novo Assembly of Large Genomic Data","funder_award_id":"1453527","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5955682675","display_name":"Computation, Bioinformatics, and Statistics (CBIOS) Training Program","funder_award_id":"T32GM102057","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7827526042","display_name":null,"funder_award_id":"1356529","funder_id":"https://openalex.org/F4320337398","funder_display_name":"Division of Biological Infrastructure"},{"id":"https://openalex.org/G8587584207","display_name":null,"funder_award_id":"DBI-1356529","funder_id":"https://openalex.org/F4320337398","funder_display_name":"Division of Biological Infrastructure"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306083","display_name":"Smithsonian Institution","ror":"https://ror.org/01pp8nd67"},{"id":"https://openalex.org/F4320309370","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10"},{"id":"https://openalex.org/F4320310419","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231"},{"id":"https://openalex.org/F4320317698","display_name":"San Diego Zoo Institute for Conservation Research","ror":"https://ror.org/04fqe9p30"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333182","display_name":"Huck Institutes of the Life Sciences","ror":null},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337398","display_name":"Division of Biological Infrastructure","ror":"https://ror.org/04qn9mx93"},{"id":"https://openalex.org/F4320337544","display_name":"Office of Extramural Research, National Institutes of Health","ror":"https://ror.org/05aq6yn88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3090950993.pdf","grobid_xml":"https://content.openalex.org/works/W3090950993.grobid-xml"},"referenced_works_count":108,"referenced_works":["https://openalex.org/W39338386","https://openalex.org/W248603601","https://openalex.org/W1561819472","https://openalex.org/W1593676244","https://openalex.org/W1596062789","https://openalex.org/W1967470558","https://openalex.org/W1969042907","https://openalex.org/W1971545385","https://openalex.org/W1972388161","https://openalex.org/W1973062929","https://openalex.org/W1974640383","https://openalex.org/W1975398519","https://openalex.org/W1977855308","https://openalex.org/W1988764596","https://openalex.org/W1998646180","https://openalex.org/W2001806320","https://openalex.org/W2008917440","https://openalex.org/W2011352335","https://openalex.org/W2013018787","https://openalex.org/W2014213609","https://openalex.org/W2019269201","https://openalex.org/W2020912279","https://openalex.org/W2021341670","https://openalex.org/W2021998028","https://openalex.org/W2024754608","https://openalex.org/W2025708809","https://openalex.org/W2026502128","https://openalex.org/W2035213969","https://openalex.org/W2037313882","https://openalex.org/W2041389096","https://openalex.org/W2055043387","https://openalex.org/W2065258504","https://openalex.org/W2065615773","https://openalex.org/W2076163156","https://openalex.org/W2076424822","https://openalex.org/W2078075583","https://openalex.org/W2080477348","https://openalex.org/W2088359631","https://openalex.org/W2089920619","https://openalex.org/W2091851394","https://openalex.org/W2095638045","https://openalex.org/W2095680943","https://openalex.org/W2097329570","https://openalex.org/W2100819216","https://openalex.org/W2102283657","https://openalex.org/W2102368172","https://openalex.org/W2102619694","https://openalex.org/W2103339246","https://openalex.org/W2103546861","https://openalex.org/W2108234281","https://openalex.org/W2111210655","https://openalex.org/W2112132489","https://openalex.org/W2114416522","https://openalex.org/W2114762781","https://openalex.org/W2114850508","https://openalex.org/W2116790427","https://openalex.org/W2124033968","https://openalex.org/W2126615487","https://openalex.org/W2126675036","https://openalex.org/W2128016314","https://openalex.org/W2134675370","https://openalex.org/W2135415406","https://openalex.org/W2137759177","https://openalex.org/W2141274012","https://openalex.org/W2141572089","https://openalex.org/W2142551861","https://openalex.org/W2143019537","https://openalex.org/W2143792049","https://openalex.org/W2146127418","https://openalex.org/W2146713153","https://openalex.org/W2150631640","https://openalex.org/W2151409320","https://openalex.org/W2156067749","https://openalex.org/W2156967983","https://openalex.org/W2159735591","https://openalex.org/W2161299849","https://openalex.org/W2165891191","https://openalex.org/W2166825456","https://openalex.org/W2259938310","https://openalex.org/W2278467601","https://openalex.org/W2324342661","https://openalex.org/W2341539131","https://openalex.org/W2472351724","https://openalex.org/W2516461792","https://openalex.org/W2586586494","https://openalex.org/W2591365011","https://openalex.org/W2591798726","https://openalex.org/W2595697491","https://openalex.org/W2611575309","https://openalex.org/W2748478565","https://openalex.org/W2754515634","https://openalex.org/W2767826728","https://openalex.org/W2899345312","https://openalex.org/W2904981155","https://openalex.org/W2910586282","https://openalex.org/W2914067549","https://openalex.org/W2950682063","https://openalex.org/W2951034138","https://openalex.org/W2951555158","https://openalex.org/W2955416413","https://openalex.org/W2963017755","https://openalex.org/W2967769217","https://openalex.org/W2973501115","https://openalex.org/W3022263142","https://openalex.org/W3111607156","https://openalex.org/W3123178128","https://openalex.org/W4394666350","https://openalex.org/W7005037217"],"related_works":["https://openalex.org/W2591798726","https://openalex.org/W3094951913","https://openalex.org/W4399121795","https://openalex.org/W2007010364","https://openalex.org/W4400959855","https://openalex.org/W6929794133","https://openalex.org/W2460270903","https://openalex.org/W4388736949","https://openalex.org/W2021998028","https://openalex.org/W2115549161"],"abstract_inverted_index":{"Abstract":[0],"The":[1,34],"mammalian":[2],"male-specific":[3,246],"Y":[4,35,112,208,237],"chromosome":[5,238],"plays":[6],"a":[7,41,65,77],"critical":[8],"role":[9],"in":[10,150,248],"sex":[11],"determination":[12],"and":[13,21,31,52,57,62,92,97,101,110,126,170,188,198,240],"male":[14],"fertility.":[15],"However,":[16],"because":[17],"of":[18,37,90,147,217,236,245],"its":[19],"repetitive":[20],"haploid":[22],"nature,":[23],"it":[24],"is":[25,47,222],"frequently":[26],"absent":[27],"from":[28,81,95],"genome":[29],"assemblies":[30,89],"remains":[32],"enigmatic.":[33],"chromosomes":[36],"great":[38,84,158,250],"apes":[39],"represent":[40],"particular":[42],"puzzle:":[43],"their":[44],"gene":[45,137,196,213,227],"content":[46],"more":[48,66],"similar":[49],"between":[50,55,187],"human":[51,56,61,169],"gorilla":[53,111],"than":[54],"chimpanzee,":[58],"even":[59],"though":[60],"chimpanzee":[63,109,125,171],"shared":[64],"recent":[67],"common":[68,160],"ancestor.":[69],"To":[70],"solve":[71],"this":[72,115],"puzzle,":[73],"here":[74],"we":[75,117,154],"constructed":[76],"dataset":[78],"including":[79,124],"Ys":[80],"all":[82],"extant":[83],"ape":[85,159,251],"genera.":[86],"We":[87,181],"generated":[88],"bonobo":[91],"orangutan":[93],"Ys,":[94],"short":[96],"long":[98],"sequencing":[99],"reads,":[100],"aligned":[102],"them":[103],"with":[104,144],"the":[105,120,157,233],"publicly":[106],"available":[107],"human,":[108],"assemblies.":[113],"Analyzing":[114],"dataset,":[116],"found":[118],"that":[119,156,207],"genus":[121],"Pan":[122,133,151],",":[123],"bonobo,":[127],"experienced":[128],"accelerated":[129],"substitution":[130],"rates.":[131,139],"Additionally,":[132],"also":[134,176,182,226],"exhibited":[135],"elevated":[136],"death":[138],"These":[140],"observations":[141],"are":[142],"consistent":[143],"high":[145],"levels":[146],"sperm":[148],"competition":[149],".":[152],"Furthermore,":[153],"inferred":[155],"ancestor":[161],"already":[162],"possessed":[163],"multi-copy":[164],"sequences":[165],"homologous":[166],"to":[167,211],"most":[168],"palindromes.":[172],"Nonetheless,":[173],"each":[174],"species":[175],"acquired":[177],"distinct":[178],"ampliconic":[179],"sequences.":[180],"detected":[183],"increased":[184],"chromatin":[185],"contacts":[186],"within":[189],"palindromes":[190,209],"(from":[191],"Hi-C":[192],"data),":[193],"likely":[194],"facilitating":[195],"conversion":[197,214],"structural":[199],"rearrangements.":[200],"Moreover,":[201],"our":[202],"ENCODE":[203],"data":[204],"analysis":[205],"suggested":[206],"exist":[210],"promote":[212],"preventing":[215],"degradation":[216],"not":[218],"only":[219],"genes,":[220],"as":[221],"commonly":[223],"believed,":[224],"but":[225],"regulatory":[228],"sites.":[229],"Our":[230],"results":[231],"highlight":[232],"dynamic":[234],"mode":[235],"evolution,":[239],"open":[241],"avenues":[242],"for":[243],"studies":[244],"dispersal":[247],"endangered":[249],"species.":[252]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-10-08T00:00:00"}