{"id":"https://openalex.org/W3090188367","doi":"https://doi.org/10.1016/j.cardfail.2020.09.156","title":"Improvement of Cardiac Structure And Function In Hereditary Transthyretin Amyloidosis Cardiomyopathy With Inotersen: A Case Report","display_name":"Improvement of Cardiac Structure And Function In Hereditary Transthyretin Amyloidosis Cardiomyopathy With Inotersen: A Case Report","publication_year":2020,"publication_date":"2020-09-30","ids":{"openalex":"https://openalex.org/W3090188367","doi":"https://doi.org/10.1016/j.cardfail.2020.09.156","mag":"3090188367"},"language":"en","primary_location":{"id":"doi:10.1016/j.cardfail.2020.09.156","doi":"https://doi.org/10.1016/j.cardfail.2020.09.156","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cardfail.2020.09.156","pdf_url":null,"source":{"id":"https://openalex.org/S67869649","display_name":"Journal of Cardiac Failure","issn_l":"1071-9164","issn":["1071-9164","1532-8414"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiac Failure","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081928873","display_name":"Rebecca R. Hung","orcid":"https://orcid.org/0000-0003-0233-0014","observed_orcids":["https://orcid.org/0000-0003-0233-0014"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca R. Hung","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075723146","display_name":"Amanda Peltier","orcid":"https://orcid.org/0000-0003-1097-7715","observed_orcids":["https://orcid.org/0000-0003-1097-7715"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda Peltier","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN","Vanderbilt University Medical Center, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Vanderbilt University Medical Center, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008364546","display_name":"Robert N. Piana","orcid":"https://orcid.org/0000-0001-6601-5318","observed_orcids":["https://orcid.org/0000-0001-6601-5318"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert N. Piana","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082462527","display_name":"SANDIP K. ZALAWADIYA","orcid":"https://orcid.org/0000-0003-4067-7844","observed_orcids":["https://orcid.org/0000-0003-4067-7844"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandip K. Zalawadiya","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069009295","display_name":"Sharon T. Shen","orcid":"https://orcid.org/0000-0002-7959-300X","observed_orcids":["https://orcid.org/0000-0002-7959-300X","https://orcid.org/0000-0002-2953-6840"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon T. Shen","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040683449","display_name":"Stacey Ann Goodman","orcid":"https://orcid.org/0000-0003-3324-8136","observed_orcids":["https://orcid.org/0000-0003-3324-8136"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stacey A. Goodman","raw_affiliation_strings":["Vanderbilt-Ingram Cancer Center, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt-Ingram Cancer Center, Nashville, TN","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031383756","display_name":"JoAnn M. Lindenfeld","orcid":"https://orcid.org/0000-0001-9207-3634","observed_orcids":["https://orcid.org/0000-0001-9207-3634"]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JoAnn Lindenfeld","raw_affiliation_strings":["Vanderbilt Heart and Vascular Institute, Nashville, TN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt Heart and Vascular Institute, Nashville, TN","institution_ids":["https://openalex.org/I901861585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2650,"currency":"USD","value_usd":2650},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0928382,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"10","first_page":"S53","last_page":"S54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/familial-amyloid-polyneuropathy","display_name":"hereditary transthyretin amyloidosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/inotersen","display_name":"inotersen","score":0.9980000257492065},{"id":"https://openalex.org/keywords/transthyretin-amyloid-cardiomyopathy","display_name":"transthyretin amyloid cardiomyopathy","score":0.746999979019165},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.7559999823570251},{"id":"https://openalex.org/keywords/diastolic-function","display_name":"diastolic function","score":0.800000011920929},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.5559999942779541},{"id":"https://openalex.org/keywords/pericardial-effusion","display_name":"pericardial effusion","score":0.8370000123977661},{"id":"https://openalex.org/keywords/sensorimotor-neuropathy","display_name":"sensorimotor neuropathy","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.968608021736145},{"id":"https://openalex.org/C121157162","wikidata":"https://www.wikidata.org/wiki/Q419999","display_name":"Transthyretin","level":2,"score":0.9404479265213013},{"id":"https://openalex.org/C2779951007","wikidata":"https://www.wikidata.org/wiki/Q816798","display_name":"Amyloidosis","level":2,"score":0.6917968988418579},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.670195460319519},{"id":"https://openalex.org/C2779962030","wikidata":"https://www.wikidata.org/wiki/Q2151267","display_name":"Restrictive cardiomyopathy","level":4,"score":0.6184890270233154},{"id":"https://openalex.org/C2777607188","wikidata":"https://www.wikidata.org/wiki/Q5038315","display_name":"Cardiac amyloidosis","level":3,"score":0.5503175854682922},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.48212122917175293},{"id":"https://openalex.org/C111566952","wikidata":"https://www.wikidata.org/wiki/Q1303462","display_name":"Cardiac function curve","level":3,"score":0.4777340590953827},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4377378225326538},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.23821309208869934}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.cardfail.2020.09.156","doi":"https://doi.org/10.1016/j.cardfail.2020.09.156","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.cardfail.2020.09.156","pdf_url":null,"source":{"id":"https://openalex.org/S67869649","display_name":"Journal of Cardiac Failure","issn_l":"1071-9164","issn":["1071-9164","1532-8414"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cardiac Failure","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8600000143051147}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2889143351","https://openalex.org/W2891818525","https://openalex.org/W4386660742","https://openalex.org/W4229644921","https://openalex.org/W2792511667","https://openalex.org/W7214902074","https://openalex.org/W2809063562","https://openalex.org/W2912011902","https://openalex.org/W2918618701","https://openalex.org/W2889324496"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2020-10-08T00:00:00"}