{"id":"https://openalex.org/W3088818596","doi":"https://doi.org/10.1016/j.colsurfb.2020.111357","title":"Role of sphingomyelin on the interaction of the anticancer drug gemcitabine hydrochloride with cell membrane models","display_name":"Role of sphingomyelin on the interaction of the anticancer drug gemcitabine hydrochloride with cell membrane models","publication_year":2020,"publication_date":"2020-09-21","ids":{"openalex":"https://openalex.org/W3088818596","doi":"https://doi.org/10.1016/j.colsurfb.2020.111357","mag":"3088818596","pmid":"https://pubmed.ncbi.nlm.nih.gov/32992284"},"language":"en","primary_location":{"id":"doi:10.1016/j.colsurfb.2020.111357","doi":"https://doi.org/10.1016/j.colsurfb.2020.111357","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfb.2020.111357","pdf_url":null,"source":{"id":"https://openalex.org/S22793308","display_name":"Colloids and Surfaces B Biointerfaces","issn_l":"0927-7765","issn":["0927-7765","1873-4367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces B: Biointerfaces","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/20.500.12733/1666130","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070491441","display_name":"Elsa M. Mater\u00f3n","orcid":"https://orcid.org/0000-0002-3382-1193","observed_orcids":["https://orcid.org/0000-0002-3382-1193"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]},{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Elsa M. Materon","raw_affiliation_strings":["Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil; S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil. Electronic address: elsa_materon@yahoo.com","Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil","S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil; S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil. Electronic address: elsa_materon@yahoo.com","institution_ids":["https://openalex.org/I177909021","https://openalex.org/I17974374","https://openalex.org/I4405267372"]},{"raw_affiliation_string":"Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil","institution_ids":["https://openalex.org/I177909021"]},{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014092483","display_name":"Gustavo Freitas do Nascimento","orcid":"https://orcid.org/0000-0001-5362-9441","observed_orcids":["https://orcid.org/0000-0001-5362-9441"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gustavo F. Nascimento","raw_affiliation_strings":["S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025642299","display_name":"Fl\u00e1vio M. Shimizu","orcid":"https://orcid.org/0000-0002-4833-9893","observed_orcids":["https://orcid.org/0000-0002-4833-9893"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Flavio M. Shimizu","raw_affiliation_strings":["S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082408362","display_name":"Amanda Souza C\u00e2mara","orcid":"https://orcid.org/0000-0002-3136-6633","observed_orcids":["https://orcid.org/0000-0002-3136-6633"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Amanda S. C\u00e2mara","raw_affiliation_strings":["S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042543854","display_name":"Bianca Sandrino","orcid":"https://orcid.org/0000-0001-7511-0077","observed_orcids":["https://orcid.org/0000-0001-7511-0077"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bianca Sandrino","raw_affiliation_strings":["S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024422131","display_name":"Ronaldo C. Faria","orcid":"https://orcid.org/0000-0003-1094-9597","observed_orcids":["https://orcid.org/0000-0003-1094-9597"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Ronaldo C. Faria","raw_affiliation_strings":["Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil. Electronic address: rcfaria@ufscar.br","Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil. Electronic address: rcfaria@ufscar.br","institution_ids":["https://openalex.org/I177909021"]},{"raw_affiliation_string":"Chemistry Department, Federal University of S\u00e3o Carlos, CP 676, S\u00e3o Carlos, 13565-905, SP, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017451457","display_name":"Osvaldo N. Oliveira","orcid":"https://orcid.org/0000-0002-5399-5860","observed_orcids":["https://orcid.org/0000-0002-5399-5860"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4405267372","display_name":"Instituto de F\u00edsica de S\u00e3o Carlos","ror":"https://ror.org/02f1crb75","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Osvaldo N. Oliveira","raw_affiliation_strings":["S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil. Electronic address: chu@ifsc.usp.br","S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil. Electronic address: chu@ifsc.usp.br","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]},{"raw_affiliation_string":"S\u00e3o Carlos Institute of Physics, University of S\u00e3o Paulo, P.O Box 369, 13560-970, S\u00e3o Carlos, SP, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4405267372"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5017451457","https://openalex.org/A5024422131","https://openalex.org/A5070491441"],"corresponding_institution_ids":["https://openalex.org/I177909021","https://openalex.org/I17974374","https://openalex.org/I4405267372"],"apc_list":{"value":2330,"currency":"USD","value_usd":2330},"apc_paid":null,"fwci":1.2149,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.77487743,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"196","issue":null,"first_page":"111357","last_page":"111357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gemcitabine","display_name":"gemcitabine","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sphingomyelin","display_name":"sphingomyelin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/drug-membrane-interactions","display_name":"drug-membrane interactions","score":0.8550000190734863},{"id":"https://openalex.org/keywords/langmuir-films","display_name":"Langmuir films","score":0.828000009059906},{"id":"https://openalex.org/keywords/model-membranes","display_name":"model membranes","score":0.7300000190734863},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.6069999933242798},{"id":"https://openalex.org/keywords/dipalmitoylphosphatidylcholine","display_name":"DPPC","score":0.5600000023841858},{"id":"https://openalex.org/keywords/dpps","display_name":"DPPS","score":0.9430000185966492},{"id":"https://openalex.org/keywords/cholesterol","display_name":"cholesterol","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pm-irras","display_name":"PM-IRRAS","score":0.7289999723434448},{"id":"https://openalex.org/keywords/molecular-dynamics-simulation","display_name":"molecular dynamics simulation","score":0.8389999866485596},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.6909999847412109},{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.77131587266922},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.706277072429657},{"id":"https://openalex.org/C61322309","wikidata":"https://www.wikidata.org/wiki/Q423143","display_name":"Sphingomyelin","level":3,"score":0.5946675539016724},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5765925049781799},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.5284454822540283},{"id":"https://openalex.org/C2776543447","wikidata":"https://www.wikidata.org/wiki/Q28734","display_name":"Nucleoside","level":2,"score":0.5191227793693542},{"id":"https://openalex.org/C2778106830","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Cell membrane","level":3,"score":0.5098785161972046},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4558117091655731},{"id":"https://openalex.org/C2780258809","wikidata":"https://www.wikidata.org/wiki/Q414143","display_name":"Gemcitabine","level":3,"score":0.4147256910800934},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.41398119926452637},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29882678389549255},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1742158830165863},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12033072113990784},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.10823079943656921},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09563952684402466},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000093542","descriptor_name":"Gemcitabine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003841","descriptor_name":"Deoxycytidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005990","descriptor_name":"Glycerol","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D010767","descriptor_name":"Phosphorylcholine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013109","descriptor_name":"Sphingomyelins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.colsurfb.2020.111357","doi":"https://doi.org/10.1016/j.colsurfb.2020.111357","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.colsurfb.2020.111357","pdf_url":null,"source":{"id":"https://openalex.org/S22793308","display_name":"Colloids and Surfaces B Biointerfaces","issn_l":"0927-7765","issn":["0927-7765","1873-4367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and Surfaces B: Biointerfaces","raw_type":"journal-article"},{"id":"pmid:32992284","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32992284","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Colloids and surfaces. B, Biointerfaces","raw_type":"Journal Article"},{"id":"pmh:oai:https://www.repositorio.unicamp.br/:1218524","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.12733/1666130","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio da Produ\u00e7\u00e3o Cient\u00edfica e Intelectual da Unicamp","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:https://www.repositorio.unicamp.br/:1218524","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.12733/1666130","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio da Produ\u00e7\u00e3o Cient\u00edfica e Intelectual da Unicamp","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G26566168","display_name":null,"funder_award_id":"2018-22214-6","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G2755372766","display_name":null,"funder_award_id":"2012/15543\u20137","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G3941884370","display_name":null,"funder_award_id":"2016/0991-5","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G8951986825","display_name":null,"funder_award_id":"2017/04712-6","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G908242994","display_name":"Development of simple electrochemical methods for the detection of biomarkers for the diagnosis of diseases","funder_award_id":"17/24053-7","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320327335","display_name":"Minist\u00e9rio da Ci\u00eancia, Tecnologia, Inova\u00e7\u00f5es e Comunica\u00e7\u00f5es","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":86,"referenced_works":["https://openalex.org/W82875452","https://openalex.org/W165853039","https://openalex.org/W1552629127","https://openalex.org/W1568317880","https://openalex.org/W1643467693","https://openalex.org/W1879047861","https://openalex.org/W1964527793","https://openalex.org/W1971793834","https://openalex.org/W1972110364","https://openalex.org/W1972321820","https://openalex.org/W1981984118","https://openalex.org/W1986524027","https://openalex.org/W1987906095","https://openalex.org/W2002642309","https://openalex.org/W2004778565","https://openalex.org/W2008357186","https://openalex.org/W2008879259","https://openalex.org/W2015768000","https://openalex.org/W2022317249","https://openalex.org/W2022779331","https://openalex.org/W2024250498","https://openalex.org/W2026433693","https://openalex.org/W2032715740","https://openalex.org/W2039078304","https://openalex.org/W2043440328","https://openalex.org/W2043567726","https://openalex.org/W2047317522","https://openalex.org/W2049619195","https://openalex.org/W2050024106","https://openalex.org/W2054755333","https://openalex.org/W2057360937","https://openalex.org/W2058213754","https://openalex.org/W2061886356","https://openalex.org/W2063114329","https://openalex.org/W2068919652","https://openalex.org/W2070550543","https://openalex.org/W2080995472","https://openalex.org/W2082064396","https://openalex.org/W2082272203","https://openalex.org/W2082359809","https://openalex.org/W2088369283","https://openalex.org/W2088990186","https://openalex.org/W2092836675","https://openalex.org/W2093656664","https://openalex.org/W2098158472","https://openalex.org/W2099612035","https://openalex.org/W2101259861","https://openalex.org/W2102509488","https://openalex.org/W2111269485","https://openalex.org/W2116752505","https://openalex.org/W2139642505","https://openalex.org/W2155864063","https://openalex.org/W2164745770","https://openalex.org/W2166963893","https://openalex.org/W2187182787","https://openalex.org/W2273151286","https://openalex.org/W2288122185","https://openalex.org/W2299907252","https://openalex.org/W2306765950","https://openalex.org/W2320798631","https://openalex.org/W2334386502","https://openalex.org/W2336717108","https://openalex.org/W2343453515","https://openalex.org/W2368005800","https://openalex.org/W2474015507","https://openalex.org/W2516981524","https://openalex.org/W2568754411","https://openalex.org/W2599649240","https://openalex.org/W2737520478","https://openalex.org/W2738122480","https://openalex.org/W2738262997","https://openalex.org/W2765635619","https://openalex.org/W2767098723","https://openalex.org/W2769383666","https://openalex.org/W2790625887","https://openalex.org/W2790705492","https://openalex.org/W2790825135","https://openalex.org/W2886443748","https://openalex.org/W2887269406","https://openalex.org/W2888234192","https://openalex.org/W2897014076","https://openalex.org/W2913295467","https://openalex.org/W2942783475","https://openalex.org/W2947629586","https://openalex.org/W2982686049","https://openalex.org/W3181280154"],"related_works":["https://openalex.org/W2093656664","https://openalex.org/W1998838741","https://openalex.org/W4311989715","https://openalex.org/W4416634382","https://openalex.org/W1964342219","https://openalex.org/W4405333339","https://openalex.org/W1594128185","https://openalex.org/W2093050653","https://openalex.org/W2123821654","https://openalex.org/W2763365861"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2020-10-01T00:00:00"}