{"id":"https://openalex.org/W3087966061","doi":"https://doi.org/10.1016/j.annonc.2020.08.918","title":"659P Rucaparib population pharmacokinetics (PPK) and exposure-response (ER) analyses in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) in TRITON2","display_name":"659P Rucaparib population pharmacokinetics (PPK) and exposure-response (ER) analyses in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) in TRITON2","publication_year":2020,"publication_date":"2020-09-01","ids":{"openalex":"https://openalex.org/W3087966061","doi":"https://doi.org/10.1016/j.annonc.2020.08.918","mag":"3087966061"},"language":"en","primary_location":{"id":"doi:10.1016/j.annonc.2020.08.918","doi":"https://doi.org/10.1016/j.annonc.2020.08.918","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2020.08.918","pdf_url":"http://www.annalsofoncology.org/article/S0923753420409147/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.annalsofoncology.org/article/S0923753420409147/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110317141","display_name":"S. Chowdhury","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I172427033","display_name":"Sarah Cannon Research Institute","ror":"https://ror.org/03cp5cj42","country_code":"GB","type":"education","lineage":["https://openalex.org/I172427033"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Chowdhury","raw_affiliation_strings":["Medical Oncology, Guy's Hospital, London, United Kingdom, and Sarah Cannon Research Institute, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Guy's Hospital, London, United Kingdom, and Sarah Cannon Research Institute, London, UK","institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I172427033"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068014441","display_name":"Akash Patnaik","orcid":"https://orcid.org/0000-0001-5306-0208","observed_orcids":["https://orcid.org/0000-0001-5306-0208"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Patnaik","raw_affiliation_strings":["Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101503071","display_name":"David Colin Campbell","orcid":"https://orcid.org/0000-0001-6298-2159","observed_orcids":["https://orcid.org/0000-0001-6298-2159"]},"institutions":[{"id":"https://openalex.org/I132157203","display_name":"Barwon Health","ror":"https://ror.org/00my0hg66","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203"]},{"id":"https://openalex.org/I2799712879","display_name":"Geelong Hospital","ror":"https://ror.org/00jrpxe15","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I132157203","https://openalex.org/I2799712879"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"D. Campbell","raw_affiliation_strings":["Medical Oncology, Barwon Health, University Hospital Geelong, Geelong, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Barwon Health, University Hospital Geelong, Geelong, Australia","institution_ids":["https://openalex.org/I132157203","https://openalex.org/I2799712879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086640363","display_name":"Jeremy David Shapiro","orcid":"https://orcid.org/0009-0007-9290-8145","observed_orcids":["https://orcid.org/0009-0007-9290-8145"]},"institutions":[{"id":"https://openalex.org/I4210093052","display_name":"Cabrini Hospital","ror":"https://ror.org/00qbkg805","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210093052"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J. Shapiro","raw_affiliation_strings":["Medical Oncology, Cabrini Hospital, Malvern, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Cabrini Hospital, Malvern, Australia","institution_ids":["https://openalex.org/I4210093052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030233600","display_name":"Alan Haruo Bryce","orcid":"https://orcid.org/0000-0002-0206-3895","observed_orcids":["https://orcid.org/0000-0002-0206-3895"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4210127938","display_name":"Mayo Clinic Hospital","ror":"https://ror.org/03660jn93","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099","https://openalex.org/I4210127938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.H. Bryce","raw_affiliation_strings":["Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ, USA","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4210127938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006249276","display_name":"Ray McDermott","orcid":"https://orcid.org/0000-0002-8952-4315","observed_orcids":["https://orcid.org/0000-0002-8952-4315"]},"institutions":[{"id":"https://openalex.org/I2803035300","display_name":"Tallaght University Hospital","ror":"https://ror.org/01fvmtt37","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2803035300"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"R. McDermott","raw_affiliation_strings":["Genito-Urinary Oncology, Adelaide and Meath Hospital (Incorporating the National Children's Hospital), Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genito-Urinary Oncology, Adelaide and Meath Hospital (Incorporating the National Children's Hospital), Dublin, Ireland","institution_ids":["https://openalex.org/I2803035300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076200732","display_name":"Brieuc R. Sautois","orcid":"https://orcid.org/0000-0002-0029-7735","observed_orcids":["https://orcid.org/0000-0002-0029-7735"]},"institutions":[{"id":"https://openalex.org/I4210134544","display_name":"Centre Hospitalier Universitaire de Li\u00e8ge","ror":"https://ror.org/044s61914","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210134544"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"B. Sautois","raw_affiliation_strings":["Medical Oncology, Li\u00e8ge University Hospital (CHU Sart Tilman), Li\u00e8ge, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Li\u00e8ge University Hospital (CHU Sart Tilman), Li\u00e8ge, Belgium","institution_ids":["https://openalex.org/I4210134544"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059219836","display_name":"Nicholas J. Vogelzang","orcid":"https://orcid.org/0000-0002-7665-6079","observed_orcids":["https://orcid.org/0000-0002-7665-6079"]},"institutions":[{"id":"https://openalex.org/I4210163348","display_name":"Comprehensive Cancer Centers of Nevada","ror":"https://ror.org/05etxbz89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210163348"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N.J. Vogelzang","raw_affiliation_strings":["Medical Oncology, Comprehensive Cancer Centers of Nevada, Las Vegas, NV, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Comprehensive Cancer Centers of Nevada, Las Vegas, NV, USA","institution_ids":["https://openalex.org/I4210163348"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078550448","display_name":"Richard Martin Bambury","orcid":"https://orcid.org/0000-0002-2189-6972","observed_orcids":["https://orcid.org/0000-0002-2189-6972"]},"institutions":[{"id":"https://openalex.org/I2802396013","display_name":"Cork University Hospital","ror":"https://ror.org/04q107642","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I2802396013"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"R. Bambury","raw_affiliation_strings":["Medical Oncology, Cork University Hospital, Cork, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Cork University Hospital, Cork, Ireland","institution_ids":["https://openalex.org/I2802396013"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006671522","display_name":"\u00c9ric Voog","orcid":"https://orcid.org/0000-0001-8366-8003","observed_orcids":["https://orcid.org/0000-0001-8366-8003"]},"institutions":[{"id":"https://openalex.org/I4210123491","display_name":"Centre Jean Bernard","ror":"https://ror.org/02s2qzh96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210123491"]},{"id":"https://openalex.org/I4210135187","display_name":"Clinique Victor Hugo","ror":"https://ror.org/04qvenw96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210135187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E. Voog","raw_affiliation_strings":["Medical Oncology, Clinique Victor Hugo Centre Jean Bernard, Le Mans, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology, Clinique Victor Hugo Centre Jean Bernard, Le Mans, France","institution_ids":["https://openalex.org/I4210123491","https://openalex.org/I4210135187"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Zhang","raw_affiliation_strings":["Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA","institution_ids":["https://openalex.org/I3019308854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103277695","display_name":"MICHELLE L. GREEN","orcid":"https://orcid.org/0000-0001-7367-9040","observed_orcids":["https://orcid.org/0000-0001-7367-9040"]},"institutions":[{"id":"https://openalex.org/I4210119960","display_name":"Certara (United States)","ror":"https://ror.org/02kxjqp24","country_code":"US","type":"company","lineage":["https://openalex.org/I4210119960"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Green","raw_affiliation_strings":["Integrated Drug Development, Certara Strategic Consulting, Menlo Park, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Drug Development, Certara Strategic Consulting, Menlo Park, CA, USA","institution_ids":["https://openalex.org/I4210119960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041178213","display_name":"Jeri Beltman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151488","display_name":"Clovis Oncology (United States)","ror":"https://ror.org/04ps4d441","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151488"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Beltman","raw_affiliation_strings":["Regulatory Affairs, Clovis Oncology, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regulatory Affairs, Clovis Oncology, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210151488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071843782","display_name":"Darrin Despain","orcid":"https://orcid.org/0000-0002-9445-8834","observed_orcids":["https://orcid.org/0000-0002-9445-8834"]},"institutions":[{"id":"https://openalex.org/I4210151488","display_name":"Clovis Oncology (United States)","ror":"https://ror.org/04ps4d441","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151488"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Despain","raw_affiliation_strings":["Biostatistics, Clovis Oncology, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics, Clovis Oncology, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210151488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103133276","display_name":"Andrew D. Simmons","orcid":"https://orcid.org/0000-0001-6075-0549","observed_orcids":["https://orcid.org/0000-0001-6075-0549"]},"institutions":[{"id":"https://openalex.org/I4210151488","display_name":"Clovis Oncology (United States)","ror":"https://ror.org/04ps4d441","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151488"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.D. Simmons","raw_affiliation_strings":["Translational Medicine, Clovis Oncology, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Medicine, Clovis Oncology, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210151488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078054913","display_name":"Simon Paul Watkins","orcid":"https://orcid.org/0000-0001-8628-8399","observed_orcids":["https://orcid.org/0000-0001-8628-8399"]},"institutions":[{"id":"https://openalex.org/I4210154258","display_name":"Clovis Oncology (United Kingdom)","ror":"https://ror.org/04j2fjp47","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151488","https://openalex.org/I4210154258"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S.P. Watkins","raw_affiliation_strings":["Clinical Science, Clovis Oncology UK, Ltd., Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Science, Clovis Oncology UK, Ltd., Cambridge, UK","institution_ids":["https://openalex.org/I4210154258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011711765","display_name":"Anthony A. Golsorkhi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151488","display_name":"Clovis Oncology (United States)","ror":"https://ror.org/04ps4d441","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151488"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Golsorkhi","raw_affiliation_strings":["Clinical Development, Clovis Oncology, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Development, Clovis Oncology, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210151488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045556668","display_name":"Jim J. Xiao","orcid":"https://orcid.org/0000-0003-3632-2012","observed_orcids":["https://orcid.org/0000-0003-3632-2012"]},"institutions":[{"id":"https://openalex.org/I4210151488","display_name":"Clovis Oncology (United States)","ror":"https://ror.org/04ps4d441","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151488"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Xiao","raw_affiliation_strings":["Clinical and Non-Clinical Pharmacology, Clovis Oncology, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Non-Clinical Pharmacology, Clovis Oncology, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210151488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062426672","display_name":"Wassim M. Abida","orcid":"https://orcid.org/0000-0002-9006-7043","observed_orcids":["https://orcid.org/0000-0002-9006-7043"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Abida","raw_affiliation_strings":["Genitourinary Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genitourinary Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":19,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2528,"currency":"USD","value_usd":2528},"apc_paid":null,"fwci":0.1806,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.5031355,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":"31","issue":null,"first_page":"S533","last_page":"S534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rucaparib","display_name":"rucaparib","score":1.0},{"id":"https://openalex.org/keywords/population-pharmacokinetics","display_name":"population pharmacokinetics","score":0.9380000233650208},{"id":"https://openalex.org/keywords/exposure-response-relationship","display_name":"exposure-response relationship","score":0.8130000233650208},{"id":"https://openalex.org/keywords/metastatic-castration-resistant-prostate-cancer","display_name":"metastatic castration-resistant prostate cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/brca1-mutation","display_name":"BRCA1 mutation","score":0.8130000233650208},{"id":"https://openalex.org/keywords/brca2-mutation","display_name":"BRCA2 mutation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/parp-inhibitors","display_name":"PARP inhibitors","score":0.9200000166893005},{"id":"https://openalex.org/keywords/drug-efficacy-and-safety","display_name":"drug safety and efficacy","score":0.7250000238418579}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9378366470336914},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.770494818687439},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5853323936462402},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.5082754492759705},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4797828793525696},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43224358558654785},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4059518575668335},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.annonc.2020.08.918","doi":"https://doi.org/10.1016/j.annonc.2020.08.918","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2020.08.918","pdf_url":"http://www.annalsofoncology.org/article/S0923753420409147/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.annonc.2020.08.918","doi":"https://doi.org/10.1016/j.annonc.2020.08.918","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.annonc.2020.08.918","pdf_url":"http://www.annalsofoncology.org/article/S0923753420409147/pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307776","display_name":"Merck","ror":"https://ror.org/02891sr49"},{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320315087","display_name":"Clovis Oncology","ror":"https://ror.org/04ps4d441"},{"id":"https://openalex.org/F4320322148","display_name":"Eisai","ror":"https://ror.org/04vvh7p27"},{"id":"https://openalex.org/F4320323024","display_name":"Astellas Pharma","ror":"https://ror.org/01cjash87"},{"id":"https://openalex.org/F4320328455","display_name":"Ipsen","ror":"https://ror.org/00d801g55"},{"id":"https://openalex.org/F4320332932","display_name":"Merck Sharp and Dohme","ror":"https://ror.org/004nn4n27"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3087966061.pdf","grobid_xml":"https://content.openalex.org/works/W3087966061.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2978095728","https://openalex.org/W4415939979","https://openalex.org/W3049351332","https://openalex.org/W4379203214","https://openalex.org/W3137926322","https://openalex.org/W4295898359","https://openalex.org/W2898270160","https://openalex.org/W7165148962","https://openalex.org/W182695913","https://openalex.org/W3006907257"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2020-10-01T00:00:00"}