{"id":"https://openalex.org/W3087612682","doi":"https://doi.org/10.1002/mgg3.1487","title":"Sjogren\u2013Larsson Syndrome: A case series of five members from an extended family with a novel mutation","display_name":"Sjogren\u2013Larsson Syndrome: A case series of five members from an extended family with a novel mutation","publication_year":2020,"publication_date":"2020-09-15","ids":{"openalex":"https://openalex.org/W3087612682","doi":"https://doi.org/10.1002/mgg3.1487","mag":"3087612682","pmid":"https://pubmed.ncbi.nlm.nih.gov/32930514","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7667322"},"language":"en","primary_location":{"id":"doi:10.1002/mgg3.1487","doi":"https://doi.org/10.1002/mgg3.1487","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mgg3.1487","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mgg3.1487","source":{"id":"https://openalex.org/S2764373787","display_name":"Molecular Genetics & Genomic Medicine","issn_l":"2324-9269","issn":["2324-9269"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Genetics & Genomic Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mgg3.1487","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013059800","display_name":"Kamel T Abidi","orcid":"https://orcid.org/0000-0002-9608-2105","observed_orcids":["https://orcid.org/0000-0002-9608-2105"]},"institutions":[{"id":"https://openalex.org/I63596082","display_name":"Tunis El Manar University","ror":"https://ror.org/029cgt552","country_code":"TN","type":"education","lineage":["https://openalex.org/I63596082"]}],"countries":["TN"],"is_corresponding":true,"raw_author_name":"Kamel T. Abidi","raw_affiliation_strings":["Faculty of Medicine, Al Manar University, Tunis, Tunisia"],"raw_orcid":"https://orcid.org/0000-0002-9608-2105","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Al Manar University, Tunis, Tunisia","institution_ids":["https://openalex.org/I63596082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000499012","display_name":"Naglaa Mohamed Kamal","orcid":"https://orcid.org/0000-0002-8535-3838","observed_orcids":["https://orcid.org/0000-0002-8535-3838"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Naglaa M. Kamal","raw_affiliation_strings":["Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt"],"raw_orcid":"https://orcid.org/0000-0002-8535-3838","affiliations":[{"raw_affiliation_string":"Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029771679","display_name":"Ayman Bakkar","orcid":"https://orcid.org/0000-0003-0266-8728","observed_orcids":["https://orcid.org/0000-0003-0266-8728"]},"institutions":[{"id":"https://openalex.org/I4210113049","display_name":"Armed Forces Hospital","ror":"https://ror.org/024eyyq66","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210113049"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ayman A. Bakkar A.","raw_affiliation_strings":["Alhada Armed Forces Hospital, Taif, KSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alhada Armed Forces Hospital, Taif, KSA","institution_ids":["https://openalex.org/I4210113049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042969990","display_name":"Maram Alotaibi","orcid":"https://orcid.org/0000-0002-6383-2301","observed_orcids":["https://orcid.org/0000-0002-6383-2301"]},"institutions":[{"id":"https://openalex.org/I4210113049","display_name":"Armed Forces Hospital","ror":"https://ror.org/024eyyq66","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210113049"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Maram Alotaibi","raw_affiliation_strings":["Alhada Armed Forces Hospital, Taif, KSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alhada Armed Forces Hospital, Taif, KSA","institution_ids":["https://openalex.org/I4210113049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024203703","display_name":"Haifa Asseri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113049","display_name":"Armed Forces Hospital","ror":"https://ror.org/024eyyq66","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210113049"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Haifa Asseri","raw_affiliation_strings":["Alhada Armed Forces Hospital, Taif, KSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alhada Armed Forces Hospital, Taif, KSA","institution_ids":["https://openalex.org/I4210113049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081934822","display_name":"Kawthar A. Bokari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I179331831","display_name":"Taif University","ror":"https://ror.org/014g1a453","country_code":"SA","type":"education","lineage":["https://openalex.org/I179331831"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Kawthar A. Bokari","raw_affiliation_strings":["Taif University, Taif, KSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Taif University, Taif, KSA","institution_ids":["https://openalex.org/I179331831"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013059800"],"corresponding_institution_ids":["https://openalex.org/I63596082"],"apc_list":{"value":2200,"currency":"USD","value_usd":2200},"apc_paid":{"value":2200,"currency":"USD","value_usd":2200},"fwci":0.1651,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.37028394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"8","issue":"11","first_page":"e1487","last_page":"e1487"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12355","display_name":"Genetic and rare skin diseases.","score":0.049400001764297485,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12331","display_name":"Hereditary Neurological Disorders","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sjogren-larsson-syndrome","display_name":"Sj\u00f6gren-Larsson syndrome","score":0.9919999837875366},{"id":"https://openalex.org/keywords/aldh3a2","display_name":"ALDH3A2","score":0.8790000081062317},{"id":"https://openalex.org/keywords/novel-mutations","display_name":"novel mutations","score":0.9309999942779541},{"id":"https://openalex.org/keywords/consanguinity","display_name":"consanguinity","score":0.6930000185966492},{"id":"https://openalex.org/keywords/congenital-ichthyosis","display_name":"congenital ichthyosis","score":0.8899999856948853},{"id":"https://openalex.org/keywords/spastic-quadriplegia","display_name":"spastic quadriplegia","score":0.9589999914169312},{"id":"https://openalex.org/keywords/intellectual-disability","display_name":"intellectual disability","score":0.9990000128746033},{"id":"https://openalex.org/keywords/developmental-delay","display_name":"developmental delay","score":0.6549999713897705},{"id":"https://openalex.org/keywords/seizures","display_name":"seizures","score":0.7960000038146973},{"id":"https://openalex.org/keywords/autosomal-recessive-disorder","display_name":"autosomal recessive disorder","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C2910530303","wikidata":"https://www.wikidata.org/wiki/Q523893","display_name":"Congenital ichthyosis","level":3,"score":0.7342494130134583},{"id":"https://openalex.org/C2776292323","wikidata":"https://www.wikidata.org/wiki/Q523893","display_name":"Ichthyosis","level":2,"score":0.7023556232452393},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6761537790298462},{"id":"https://openalex.org/C551499885","wikidata":"https://www.wikidata.org/wiki/Q183560","display_name":"Intellectual disability","level":2,"score":0.5298941731452942},{"id":"https://openalex.org/C2779923321","wikidata":"https://www.wikidata.org/wiki/Q774347","display_name":"Consanguinity","level":2,"score":0.506625235080719},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.4737359285354614},{"id":"https://openalex.org/C80227256","wikidata":"https://www.wikidata.org/wiki/Q1124169","display_name":"Genetic counseling","level":2,"score":0.4380742013454437},{"id":"https://openalex.org/C2781306077","wikidata":"https://www.wikidata.org/wiki/Q944758","display_name":"Tetraplegia","level":4,"score":0.426611065864563},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.42053985595703125},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4182397127151489},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.41406959295272827},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3196876049041748},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22818085551261902},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14581167697906494},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.09698596596717834},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.07617023587226868},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000445","descriptor_name":"Aldehyde Oxidoreductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006579","descriptor_name":"Heterozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006720","descriptor_name":"Homozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016111","descriptor_name":"Sjogren-Larsson Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016111","descriptor_name":"Sjogren-Larsson Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/mgg3.1487","doi":"https://doi.org/10.1002/mgg3.1487","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mgg3.1487","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mgg3.1487","source":{"id":"https://openalex.org/S2764373787","display_name":"Molecular Genetics & Genomic Medicine","issn_l":"2324-9269","issn":["2324-9269"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Genetics & Genomic Medicine","raw_type":"journal-article"},{"id":"pmid:32930514","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32930514","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular genetics & genomic medicine","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:7667322","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7667322/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Genet Genomic Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:6a62e44c07444112946fabe035096b28","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6a62e44c07444112946fabe035096b28","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Genetics & Genomic Medicine, Vol 8, Iss 11, Pp n/a-n/a (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/mgg3.1487","doi":"https://doi.org/10.1002/mgg3.1487","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mgg3.1487","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mgg3.1487","source":{"id":"https://openalex.org/S2764373787","display_name":"Molecular Genetics & Genomic Medicine","issn_l":"2324-9269","issn":["2324-9269"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Genetics & Genomic Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3087612682.pdf","grobid_xml":"https://content.openalex.org/works/W3087612682.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W344501223","https://openalex.org/W1968355580","https://openalex.org/W1970051213","https://openalex.org/W2006870601","https://openalex.org/W2007677013","https://openalex.org/W2016675948","https://openalex.org/W2035571161","https://openalex.org/W2043479533","https://openalex.org/W2045314917","https://openalex.org/W2055937309","https://openalex.org/W2098195164","https://openalex.org/W2125439069","https://openalex.org/W2169905556","https://openalex.org/W2300608143","https://openalex.org/W2546922369","https://openalex.org/W2617341740","https://openalex.org/W2766531129","https://openalex.org/W2997921514","https://openalex.org/W3147051068"],"related_works":["https://openalex.org/W4390577918","https://openalex.org/W2770438505","https://openalex.org/W2953958188","https://openalex.org/W2073132148","https://openalex.org/W2966383427","https://openalex.org/W2043479533","https://openalex.org/W7101123702","https://openalex.org/W1963603520","https://openalex.org/W2769651496","https://openalex.org/W2117715078"],"abstract_inverted_index":{"BACKGROUNDD:":[0],"Sjogren-Larsson":[1],"syndrome":[2],"(SLS)":[3],"is":[4,169],"a":[5,12,27,105,143],"rare":[6],"autosomal":[7],"recessive":[8],"disorder,":[9],"characterized":[10],"by":[11,76],"triad":[13,144],"of":[14,72,98,107,119,145,155],"spastic":[15,150],"tetraplegia":[16],"or":[17],"diplegia,":[18],"congenital":[19],"ichthyosis,":[20,146],"and":[21,62,68,149],"intellectual":[22,147],"disability.":[23],"METHODS:":[24],"We":[25],"report":[26],"seven-years-old":[28],"female":[29],"born":[30],"to":[31,104,162],"consanguineous":[32],"parents":[33],"who":[34],"presented":[35],"with":[36,58,130,142],"erythematous":[37],"dry":[38],"scaly":[39],"skin":[40],"all":[41],"over":[42],"the":[43,46,73,82,99,108,115,120,131,156,164],"body":[44],"sparing":[45],"face,":[47],"without":[48],"collodion":[49],"membrane":[50],"which":[51],"started":[52],"since":[53],"birth.":[54],"There":[55],"were":[56],"associated":[57],"global":[59],"developmental":[60],"delay":[61],"seizure":[63],"disorder.":[64],"SLS":[65,135],"was":[66,79,112],"suspected":[67,138],"hence":[69],"sequence":[70,110],"analysis":[71],"ALDH3A2":[74,100,157],"gene":[75,101,158],"next-generation":[77],"sequencing":[78],"performed":[80,161],"for":[81],"patient.":[83,116],"RESULTS:":[84],"A":[85],"novel":[86],"nucleotide":[87],"exchange":[88],"in":[89,95,114,139],"homozygous":[90],"state":[91],"at":[92],"position":[93],"c.1320":[94],"exon":[96],"9":[97],"(c.1320T>A),":[102],"leading":[103],"stop":[106],"protein":[109],"(p.Tyr440)":[111],"detected":[113],"Genetic":[117],"testing":[118,154],"patient's":[121],"extended":[122],"family":[123,128,167],"revealed":[124],"another":[125],"four":[126],"affected":[127],"members":[129],"same":[132],"mutation.":[133],"CONCLUSIONS:":[134],"should":[136,159],"be":[137,160],"any":[140],"patient":[141],"disability":[148],"di/tetraplegia.":[151],"Molecular":[152],"genetic":[153],"confirm":[163],"diagnosis.":[165],"Extended":[166],"screening":[168],"highly":[170],"recommended.":[171]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-09-25T00:00:00"}