{"id":"https://openalex.org/W308674330","doi":"https://doi.org/10.21236/ada436701","title":"DNA Based Fluid Computing Using Methylation","display_name":"DNA Based Fluid Computing Using Methylation","publication_year":2005,"publication_date":"2005-08-01","ids":{"openalex":"https://openalex.org/W308674330","doi":"https://doi.org/10.21236/ada436701","mag":"308674330"},"language":"en","primary_location":{"id":"doi:10.21236/ada436701","doi":"https://doi.org/10.21236/ada436701","is_oa":false,"landing_page_url":"http://doi.org/10.21236/ada436701","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"US Dept of the Army","raw_type":"report"},"volume":null,"type":"report","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004382849","display_name":"Thomas J. Head","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas J. Head","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5024756657","display_name":"Susannah Gal","orcid":"https://orcid.org/0000-0001-5422-7807","observed_orcids":["https://orcid.org/0000-0001-5422-7807"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susannah Gal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12002","display_name":"Computability, Logic, AI Algorithms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-computing","display_name":"DNA computing","score":0.8679999709129333},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8849999904632568},{"id":"https://openalex.org/keywords/sat-problem","display_name":"SAT problem","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7086203098297119},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.501885175704956},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4790709912776947},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4643082916736603},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.42528772354125977},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3087621033191681},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26368993520736694},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0900246798992157},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.21236/ada436701","doi":"https://doi.org/10.21236/ada436701","is_oa":false,"landing_page_url":"http://doi.org/10.21236/ada436701","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"US Dept of the Army","raw_type":"report"},{"id":"pmh:ADA436701","doi":null,"is_oa":false,"landing_page_url":"http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA436701","pdf_url":null,"source":{"id":"https://openalex.org/S4406923043","display_name":"Defense Technical Information Center (DTIC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"DTIC AND NTIS","raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2189091026","https://openalex.org/W1975874012","https://openalex.org/W2117620684","https://openalex.org/W1541609833","https://openalex.org/W2922261103","https://openalex.org/W2525009737","https://openalex.org/W2321037296","https://openalex.org/W1556317584","https://openalex.org/W4245016019","https://openalex.org/W2179321056"],"abstract_inverted_index":{"Future":[0],"advances":[1],"in":[2,40,62],"computing":[3,29],"technology":[4],"require":[5],"exploration":[6],"of":[7,17,22,37,44,51,82,95,105],"next":[8],"generation":[9],"strategies.":[10],"Approaches":[11],"that":[12],"use":[13],"the":[14,23,35,59,93,111],"ultra-parallel":[15],"processing":[16],"bio-molecular":[18],"procedures":[19],"are":[20],"one":[21],"most":[24],"intriguing":[25],"strategies":[26,32],"for":[27,34,97,120],"new":[28],"paradigms.":[30],"These":[31],"provide":[33],"solution":[36,81],"many":[38],"algorithms":[39,84],"a":[41,63,69,87,103,138],"linear":[42],"number":[43,50,104],"steps":[45,52],"compared":[46],"to":[47,78,136],"an":[48],"exponential":[49],"with":[53],"traditional":[54],"computing.":[55],"Using":[56],"DNA":[57,123,129],"as":[58],"memory":[60],"register":[61],"fluid":[64],"environment":[65],"like":[66],"water":[67],"is":[68],"strategy":[70,119,133],"called":[71],"aqueous":[72],"computing.\"":[73],"It":[74],"has":[75,100],"been":[76,101,108],"used":[77,135],"achieve":[79],"successful":[80],"simple":[83],"based":[85],"on":[86,122],"restriction":[88],"enzyme":[89],"writing":[90,121],"procedure.":[91],"While":[92],"proof":[94],"concept":[96],"this":[98,116,132],"approach":[99],"achieved":[102],"challenges":[106],"have":[107],"identified":[109],"including":[110],"long":[112],"time":[113],"required.":[114],"For":[115],"grant":[117],"another":[118],"was":[124,134],"investigated":[125],"using":[126],"sequence":[127],"specific":[128],"methylation":[130],"and":[131],"solve":[137],"4-variable":[139],"SAT":[140],"problem.":[141]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}