{"id":"https://openalex.org/W3086575470","doi":null,"title":"The adaptor protein CARD9, from fungal immunity to tumorigenesis.","display_name":"The adaptor protein CARD9, from fungal immunity to tumorigenesis.","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3086575470","mag":"3086575470","pmid":"https://pubmed.ncbi.nlm.nih.gov/32905547","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7471374"},"language":"en","primary_location":{"id":"pmid:32905547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32905547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cancer research","raw_type":"Journal Article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7471374/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100347089","display_name":"Ying Wang","orcid":"https://orcid.org/0000-0002-3877-4816","observed_orcids":["https://orcid.org/0000-0002-3877-4816"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Wang","raw_affiliation_strings":["The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100366379","display_name":"Di Zhang","orcid":"https://orcid.org/0000-0001-8978-2130","observed_orcids":["https://orcid.org/0000-0001-8978-2130","https://orcid.org/0000-0001-8760-1412"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Zhang","raw_affiliation_strings":["The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100700022","display_name":"Yayi Hou","orcid":"https://orcid.org/0000-0002-1152-9132","observed_orcids":["https://orcid.org/0000-0002-1152-9132"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yayi Hou","raw_affiliation_strings":["The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","Jiangsu Key Laboratory of Molecular Medicine Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Molecular Medicine Nanjing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102496496","display_name":"Sunan Shen","orcid":"https://orcid.org/0009-0000-0891-2213","observed_orcids":["https://orcid.org/0009-0000-0891-2213"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sunan Shen","raw_affiliation_strings":["The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","Jiangsu Key Laboratory of Molecular Medicine Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Molecular Medicine Nanjing, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100447724","display_name":"Tingting Wang","orcid":"https://orcid.org/0000-0002-2963-0888","observed_orcids":["https://orcid.org/0000-0002-2963-0888"]},"institutions":[{"id":"https://openalex.org/I4391768045","display_name":"State Key Laboratory of Pharmaceutical Biotechnology","ror":"https://ror.org/043ea4m21","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"id":"https://openalex.org/I881766915","display_name":"Nanjing University","ror":"https://ror.org/01rxvg760","country_code":"CN","type":"education","lineage":["https://openalex.org/I881766915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting Wang","raw_affiliation_strings":["The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","Jiangsu Key Laboratory of Molecular Medicine Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School of Nanjing University Nanjing 210093, China","institution_ids":["https://openalex.org/I4391768045","https://openalex.org/I881766915"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Molecular Medicine Nanjing, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4994,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.47184522,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"10","issue":"8","first_page":"2203","last_page":"2225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.8705999851226807,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.8705999851226807,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.09080000221729279,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/card9","display_name":"CARD9","score":0.9940000176429749},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.8529999852180481},{"id":"https://openalex.org/keywords/antifungal-immunity","display_name":"antifungal immunity","score":0.7009999752044678},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8080000281333923},{"id":"https://openalex.org/keywords/pattern-recognition-receptors","display_name":"pattern recognition receptors","score":0.9610000252723694},{"id":"https://openalex.org/keywords/myeloid-cells","display_name":"myeloid cells","score":0.9670000076293945},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9279999732971191},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6809999942779541},{"id":"https://openalex.org/keywords/card9-deficiency","display_name":"CARD9 deficiency","score":0.6790000200271606},{"id":"https://openalex.org/keywords/adaptive-immune-response","display_name":"adaptive immune response","score":0.5070000290870667},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.5299999713897705}],"concepts":[{"id":"https://openalex.org/C183786373","wikidata":"https://www.wikidata.org/wiki/Q5964993","display_name":"Signal transducing adaptor protein","level":3,"score":0.8091297745704651},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.6541056632995605},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6497715711593628},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6211477518081665},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.6071146130561829},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5770943760871887},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5738719701766968},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.5393208861351013},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5030011534690857},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.49546849727630615},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4292905926704407},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3903292417526245},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3714148998260498},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3067474663257599},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11645156145095825},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09506285190582275}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:32905547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32905547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cancer research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7471374","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7471374/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cancer Res","raw_type":"Text"},{"id":"mag:3086575470","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32905547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7471374","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7471374/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cancer Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":140,"referenced_works":["https://openalex.org/W1519886765","https://openalex.org/W1563034495","https://openalex.org/W1600472471","https://openalex.org/W1733554212","https://openalex.org/W1846119031","https://openalex.org/W1881072801","https://openalex.org/W1907842654","https://openalex.org/W1963651279","https://openalex.org/W1964435410","https://openalex.org/W1964465182","https://openalex.org/W1968052811","https://openalex.org/W1970602376","https://openalex.org/W1973037661","https://openalex.org/W1974366841","https://openalex.org/W1976790296","https://openalex.org/W1982029015","https://openalex.org/W1985371834","https://openalex.org/W1987625474","https://openalex.org/W1988604605","https://openalex.org/W1988820663","https://openalex.org/W1988822418","https://openalex.org/W1990530060","https://openalex.org/W1991332015","https://openalex.org/W1994942139","https://openalex.org/W1995629350","https://openalex.org/W1995744610","https://openalex.org/W1996644651","https://openalex.org/W1998876965","https://openalex.org/W2002836781","https://openalex.org/W2004150448","https://openalex.org/W2004336750","https://openalex.org/W2006305038","https://openalex.org/W2006711580","https://openalex.org/W2008415419","https://openalex.org/W2010822247","https://openalex.org/W2013277175","https://openalex.org/W2013417742","https://openalex.org/W2016862474","https://openalex.org/W2017341404","https://openalex.org/W2018705412","https://openalex.org/W2024183493","https://openalex.org/W2024490058","https://openalex.org/W2025355874","https://openalex.org/W2027342983","https://openalex.org/W2027562913","https://openalex.org/W2029663467","https://openalex.org/W2029986440","https://openalex.org/W2030928351","https://openalex.org/W2033289727","https://openalex.org/W2034272719","https://openalex.org/W2036619734","https://openalex.org/W2039348492","https://openalex.org/W2041170922","https://openalex.org/W2043173265","https://openalex.org/W2049309853","https://openalex.org/W2051307540","https://openalex.org/W2053261474","https://openalex.org/W2055572755","https://openalex.org/W2056450591","https://openalex.org/W2057784243","https://openalex.org/W2059507666","https://openalex.org/W2060610804","https://openalex.org/W2060938552","https://openalex.org/W2065666266","https://openalex.org/W2069949336","https://openalex.org/W2074795280","https://openalex.org/W2075691631","https://openalex.org/W2076361525","https://openalex.org/W2080860848","https://openalex.org/W2083498707","https://openalex.org/W2086105638","https://openalex.org/W2086607027","https://openalex.org/W2087608197","https://openalex.org/W2092807701","https://openalex.org/W2097804771","https://openalex.org/W2098596185","https://openalex.org/W2101286028","https://openalex.org/W2101524137","https://openalex.org/W2102829493","https://openalex.org/W2105074631","https://openalex.org/W2105683217","https://openalex.org/W2107495112","https://openalex.org/W2107531246","https://openalex.org/W2109491705","https://openalex.org/W2109724505","https://openalex.org/W2126924404","https://openalex.org/W2133102126","https://openalex.org/W2134960373","https://openalex.org/W2135649725","https://openalex.org/W2137823685","https://openalex.org/W2140333814","https://openalex.org/W2141727194","https://openalex.org/W2144584101","https://openalex.org/W2145709723","https://openalex.org/W2146560737","https://openalex.org/W2149622022","https://openalex.org/W2153035768","https://openalex.org/W2153422814","https://openalex.org/W2156459362","https://openalex.org/W2159460252","https://openalex.org/W2160799132","https://openalex.org/W2164514035","https://openalex.org/W2166909888","https://openalex.org/W2167727786","https://openalex.org/W2170191276","https://openalex.org/W2171900919","https://openalex.org/W2214893803","https://openalex.org/W2266683146","https://openalex.org/W2274509164","https://openalex.org/W2287887328","https://openalex.org/W2313428973","https://openalex.org/W2335925695","https://openalex.org/W2338977287","https://openalex.org/W2346752870","https://openalex.org/W2419660348","https://openalex.org/W2527009712","https://openalex.org/W2537967741","https://openalex.org/W2549345337","https://openalex.org/W2560033799","https://openalex.org/W2560959018","https://openalex.org/W2584062940","https://openalex.org/W2606539063","https://openalex.org/W2621838619","https://openalex.org/W2747461977","https://openalex.org/W2751712853","https://openalex.org/W2753222026","https://openalex.org/W2765371057","https://openalex.org/W2786334128","https://openalex.org/W2789586210","https://openalex.org/W2804029398","https://openalex.org/W2887602332","https://openalex.org/W2888376450","https://openalex.org/W2890491535","https://openalex.org/W2891823700","https://openalex.org/W2912852672","https://openalex.org/W2921241315","https://openalex.org/W2941973995","https://openalex.org/W2943293743","https://openalex.org/W2948132055","https://openalex.org/W2979306188"],"related_works":["https://openalex.org/W2970396105","https://openalex.org/W2790060323","https://openalex.org/W2886946434","https://openalex.org/W4392110559","https://openalex.org/W2891823700","https://openalex.org/W3026027040","https://openalex.org/W2921241315","https://openalex.org/W1990530060","https://openalex.org/W1974366841","https://openalex.org/W4308653003"],"abstract_inverted_index":{"The":[0,54],"adaptor":[1],"protein":[2],"CARD9":[3,20,33,43,71,112,120],"is":[4,62,72],"in":[5,25,59,121],"charge":[6],"of":[7,12,56,77,85,100,119,124],"mediating":[8],"signals":[9],"from":[10,128],"PRRs":[11],"myeloid":[13],"cells":[14],"to":[15,38,131],"downstream":[16,97],"transcription":[17],"factor":[18],"NF-\u03baB.":[19],"plays":[21],"an":[22],"indispensable":[23],"role":[24,55],"innate":[26],"immunity.":[27,87],"Both":[28],"mice":[29],"and":[30,40,80,96,108],"humans":[31],"with":[32,74],"deficiency":[34],"show":[35],"increased":[36],"susceptibility":[37],"fungal":[39,129],"bacterial":[41],"infections.":[42],"signaling":[44,98],"not":[45],"only":[46],"activates":[47],"but":[48],"also":[49],"shapes":[50],"adaptive":[51],"immune":[52],"responses.":[53],"this":[57,89],"molecule":[58],"tumor":[60],"progression":[61],"increasingly":[63],"being":[64],"revealed.":[65],"Our":[66],"early":[67],"study":[68],"found":[69],"that":[70],"associated":[73],"the":[75,94,105,117],"development":[76],"colon":[78],"cancer":[79],"functions":[81],"as":[82],"a":[83],"regulator":[84],"antitumor":[86],"In":[88],"review,":[90],"we":[91,103,115],"focus":[92],"on":[93],"upstream":[95],"pathways":[99],"CARD9,":[101],"then":[102],"summarize":[104],"immunological":[106],"recognition":[107],"responses":[109],"induced":[110],"by":[111],"signaling.":[113],"Furthermore,":[114],"review":[116],"function":[118],"multiple":[122],"aspects":[123],"host":[125],"immunity,":[126],"ranging":[127],"immunity":[130],"tumorigenesis.":[132]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-09-21T00:00:00"}