{"id":"https://openalex.org/W3085843329","doi":null,"title":"Electronic cigarettes promotes the lung colonization of human breast cancer in NOD-SCID-Gamma mice.","display_name":"Electronic cigarettes promotes the lung colonization of human breast cancer in NOD-SCID-Gamma mice.","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3085843329","mag":"3085843329","pmid":"https://pubmed.ncbi.nlm.nih.gov/32922603","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7476960"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7476960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7476960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7476960","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Do Huynh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Do Huynh","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021196514","display_name":"Jing Huang","orcid":"https://orcid.org/0000-0001-7234-7749","observed_orcids":["https://orcid.org/0000-0001-7234-7749"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jing Huang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001241385","display_name":"Le Le","orcid":"https://orcid.org/0000-0002-1013-2328","observed_orcids":["https://orcid.org/0000-0002-1013-2328"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Le Thi Thu Le","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101979291","display_name":"Dongfang Liu","orcid":"https://orcid.org/0000-0002-7295-8088","observed_orcids":["https://orcid.org/0000-0002-7295-8088"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]},{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dongfang Liu","raw_affiliation_strings":["Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142","https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322216","display_name":"Chen Liu","orcid":"https://orcid.org/0009-0003-0430-6146","observed_orcids":["https://orcid.org/0009-0003-0430-6146","https://orcid.org/0009-0008-6552-1719"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]},{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chen Liu","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142","https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074733951","display_name":"Kien Pham","orcid":"https://orcid.org/0000-0002-3839-8777","observed_orcids":["https://orcid.org/0000-0002-3839-8777"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]},{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kien Pham","raw_affiliation_strings":["Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Immunology & Laboratory Medicine, New Jersey Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142","https://openalex.org/I4402554120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100351651","display_name":"He Wang","orcid":"https://orcid.org/0000-0001-9736-8028","observed_orcids":["https://orcid.org/0000-0001-9736-8028"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"He Wang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Robert Wood Johnson Medical School, Rutgers University New Brunswick, NJ","institution_ids":["https://openalex.org/I102322142"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6016,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.66789768,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"13","issue":"8","first_page":"2075","last_page":"2081"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.7383000254631042,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.22220000624656677,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/e-cigarettes","display_name":"electronic cigarettes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9070000052452087},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.8679999709129333},{"id":"https://openalex.org/keywords/lung-colonization","display_name":"lung colonization","score":0.7570000290870667},{"id":"https://openalex.org/keywords/nicotine","display_name":"nicotine","score":0.6520000100135803},{"id":"https://openalex.org/keywords/propylene-glycol","display_name":"propylene glycol","score":0.9539999961853027},{"id":"https://openalex.org/keywords/vegetable-glycerin","display_name":"vegetable glycerin","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tumor-cell-apoptosis","display_name":"tumor cell apoptosis","score":0.7850000262260437},{"id":"https://openalex.org/keywords/nsg-mice","display_name":"NSG mice","score":0.8569999933242798},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.3889999985694885}],"concepts":[{"id":"https://openalex.org/C55851684","wikidata":"https://www.wikidata.org/wiki/Q518390","display_name":"Nod","level":3,"score":0.6278687715530396},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5974576473236084},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.586898148059845},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.573624312877655},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.5662726759910583},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5500749349594116},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.546375572681427},{"id":"https://openalex.org/C2910938049","wikidata":"https://www.wikidata.org/wiki/Q7249605","display_name":"Proliferation index","level":3,"score":0.5431269407272339},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5157668590545654},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.49137821793556213},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48969796299934387},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.45283791422843933},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3744363486766815},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.34689685702323914},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3238702714443207},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30907177925109863},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2831685245037079},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2191815972328186},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.17992925643920898},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.09727483987808228},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.07346081733703613},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:7476960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7476960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},{"id":"pmid:32922603","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32922603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental pathology","raw_type":"Journal Article"},{"id":"mag:3085843329","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32922603","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7476960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7476960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Pathol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8799999952316284,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1962333895","https://openalex.org/W2068692704","https://openalex.org/W2073020829","https://openalex.org/W2127239893","https://openalex.org/W2136331843","https://openalex.org/W2150186781","https://openalex.org/W2159517121","https://openalex.org/W2166616170","https://openalex.org/W2333316562","https://openalex.org/W2341251987","https://openalex.org/W2436535962","https://openalex.org/W2592041527","https://openalex.org/W2619271491","https://openalex.org/W2792127636","https://openalex.org/W2794485348","https://openalex.org/W2801168812","https://openalex.org/W2808349922","https://openalex.org/W2885715071","https://openalex.org/W2895967338","https://openalex.org/W2900031798","https://openalex.org/W2964360283","https://openalex.org/W2967084013","https://openalex.org/W2977991958","https://openalex.org/W4211005384"],"related_works":["https://openalex.org/W2977991958","https://openalex.org/W1997771120","https://openalex.org/W4411279177","https://openalex.org/W2600937621","https://openalex.org/W1563155904","https://openalex.org/W3080458939","https://openalex.org/W4362542881","https://openalex.org/W4405576950","https://openalex.org/W2980833448","https://openalex.org/W2282020561"],"abstract_inverted_index":{",":[0],"we":[1],"used":[2],"NOD-SCID-Gamma":[3],"mice":[4,11],"and":[5,108],"introduced":[6],"tumor":[7,40,60,67],"cells":[8,61],"to":[9,47],"the":[10,39,43,56,64,79,83,97,102,113],"by":[12],"tail":[13],"vein":[14],"injection.":[15],"Among":[16],"these":[17],"mice,":[18],"4-week":[19],"E-cigs":[20,88,100],"exposure":[21,52],"(nicotine":[22],"24":[23],"mg/ml,":[24],"propylene":[25],"glycol":[26],"50%,":[27,30],"vegetable":[28],"glycerin":[29],"no":[31],"flavorings,":[32],"2":[33],"h/day,":[34],"5":[35],"days/week)":[36],"almost":[37],"doubled":[38],"load":[41],"in":[42,63],"exposed":[44],"lungs":[45,65],"compared":[46],"controls":[48],"(P=0.0036).":[49],"While":[50],"E-cig":[51],"did":[53],"not":[54],"alter":[55],"proliferative":[57],"index":[58],"of":[59,87,99,105],"colonized":[62],"(P=0.7953),":[66],"cell":[68],"apoptosis":[69],"was":[70],"significantly":[71],"reduced":[72],"(P<0.001).":[73],"Taken":[74],"together,":[75],"our":[76],"data":[77],"for":[78],"first":[80],"time,":[81],"demonstrated":[82],"lung":[84,103],"colonization-promoting":[85],"effects":[86],"on":[89,101,112],"human":[90],"breast":[91],"cancer":[92],"cells.":[93],"These":[94],"findings":[95],"show":[96],"risks":[98],"metastasis":[104],"various":[106],"cancers,":[107],"warrant":[109],"more":[110],"studies":[111],"underlying":[114],"mechanisms.":[115]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2020-09-21T00:00:00"}