{"id":"https://openalex.org/W3085772379","doi":"https://doi.org/10.1093/ecco-jcc/jjaa178","title":"Dissecting Common and Unique Effects of Anti-\u03b14\u03b27 and Anti-Tumor Necrosis Factor Treatment in Ulcerative Colitis","display_name":"Dissecting Common and Unique Effects of Anti-\u03b14\u03b27 and Anti-Tumor Necrosis Factor Treatment in Ulcerative Colitis","publication_year":2020,"publication_date":"2020-09-11","ids":{"openalex":"https://openalex.org/W3085772379","doi":"https://doi.org/10.1093/ecco-jcc/jjaa178","mag":"3085772379","pmid":"https://pubmed.ncbi.nlm.nih.gov/32926095","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7944518"},"language":"en","primary_location":{"id":"doi:10.1093/ecco-jcc/jjaa178","doi":"https://doi.org/10.1093/ecco-jcc/jjaa178","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ecco-jcc/jjaa178","pdf_url":"https://academic.oup.com/ecco-jcc/article-pdf/15/3/441/36463160/jjaa178.pdf","source":{"id":"https://openalex.org/S2735960814","display_name":"Journal of Crohn s and Colitis","issn_l":"1873-9946","issn":["1873-9946","1876-4479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Crohn's and Colitis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/ecco-jcc/article-pdf/15/3/441/36463160/jjaa178.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008552726","display_name":"Marisol Veny","orcid":"https://orcid.org/0000-0002-5702-4789","observed_orcids":["https://orcid.org/0000-0002-5702-4789"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Marisol Veny","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077883605","display_name":"Alba Garrido-Trigo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alba Garrido-Trigo","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046862803","display_name":"Ana Maria Corraliza","orcid":"https://orcid.org/0000-0002-3067-7763","observed_orcids":["https://orcid.org/0000-0002-3067-7763"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ana M Corraliza","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010303736","display_name":"Maria Carme Masamunt","orcid":"https://orcid.org/0000-0001-8736-1623","observed_orcids":["https://orcid.org/0000-0001-8736-1623"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Maria C Masamunt","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029609860","display_name":"Helena Bassolas-Molina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Helena Bassolas-Molina","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084515363","display_name":"M\u00edriam Esteller","orcid":"https://orcid.org/0000-0001-5770-9086","observed_orcids":["https://orcid.org/0000-0001-5770-9086"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Miriam Esteller","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066214057","display_name":"Montserrat Arroyes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Montserrat Arroyes","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034908898","display_name":"Eva Trist\u00e1n","orcid":"https://orcid.org/0000-0002-9317-2447","observed_orcids":["https://orcid.org/0000-0002-9317-2447"]},"institutions":[{"id":"https://openalex.org/I4210096566","display_name":"University Hospital M\u00fatua de Terrassa","ror":"https://ror.org/011335j04","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210096566","https://openalex.org/I4210130102"]},{"id":"https://openalex.org/I4210130102","display_name":"M\u00fatua Terrassa","ror":"https://ror.org/02h74qa12","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210130102"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Eva Trist\u00e1n","raw_affiliation_strings":["Hospital Universitari Mutua Terrassa, CIBERehd, Department of Gastroenterology, Terrassa, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universitari Mutua Terrassa, CIBERehd, Department of Gastroenterology, Terrassa, Spain","institution_ids":["https://openalex.org/I4210096566","https://openalex.org/I4210130102","https://openalex.org/I4210132431"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079935064","display_name":"Agnes Fernandez-Clotet","orcid":"https://orcid.org/0000-0001-7513-0764","observed_orcids":["https://orcid.org/0000-0001-7513-0764"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Agn\u00e8s Fern\u00e1ndez-Clotet","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086449665","display_name":"\u00cdngrid Ord\u00e1s","orcid":"https://orcid.org/0000-0001-7632-0340","observed_orcids":["https://orcid.org/0000-0001-7632-0340"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ingrid Ord\u00e1s","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015665559","display_name":"Elena Ricart","orcid":"https://orcid.org/0000-0003-3354-1594","observed_orcids":["https://orcid.org/0000-0003-3354-1594"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Elena Ricart","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046814332","display_name":"Mar\u00eda Esteve","orcid":"https://orcid.org/0000-0001-7716-0027","observed_orcids":["https://orcid.org/0000-0001-7716-0027"]},"institutions":[{"id":"https://openalex.org/I4210096566","display_name":"University Hospital M\u00fatua de Terrassa","ror":"https://ror.org/011335j04","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210096566","https://openalex.org/I4210130102"]},{"id":"https://openalex.org/I4210130102","display_name":"M\u00fatua Terrassa","ror":"https://ror.org/02h74qa12","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210130102"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Maria Esteve","raw_affiliation_strings":["Hospital Universitari Mutua Terrassa, CIBERehd, Department of Gastroenterology, Terrassa, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universitari Mutua Terrassa, CIBERehd, Department of Gastroenterology, Terrassa, Spain","institution_ids":["https://openalex.org/I4210096566","https://openalex.org/I4210130102","https://openalex.org/I4210132431"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040354010","display_name":"Juli\u00e1n Pan\u00e9s","orcid":"https://orcid.org/0000-0002-4971-6902","observed_orcids":["https://orcid.org/0000-0002-4971-6902"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Julian Pan\u00e9s","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039924630","display_name":"Azucena Salas","orcid":"https://orcid.org/0000-0003-4572-2907","observed_orcids":["https://orcid.org/0000-0003-4572-2907"]},"institutions":[{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210132431","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210132431"]},{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210115097","https://openalex.org/I4210160192","https://openalex.org/I4387153040","https://openalex.org/I4403928279"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Azucena Salas","raw_affiliation_strings":["Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain"],"raw_orcid":"https://orcid.org/0000-0003-4572-2907","affiliations":[{"raw_affiliation_string":"Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd), Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5039924630"],"corresponding_institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210132431","https://openalex.org/I4210160192"],"apc_list":{"value":4238,"currency":"EUR","value_usd":4790},"apc_paid":{"value":4238,"currency":"EUR","value_usd":4790},"fwci":2.3218,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.88351359,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"15","issue":"3","first_page":"441","last_page":"452"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/vedolizumab","display_name":"vedolizumab","score":1.0}],"concepts":[{"id":"https://openalex.org/C2776207728","wikidata":"https://www.wikidata.org/wiki/Q7918002","display_name":"Vedolizumab","level":4,"score":0.9897158145904541},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8726929426193237},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.863571047782898},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.6976529359817505},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5543215870857239},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5477551221847534},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.4861590564250946},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4192013740539551},{"id":"https://openalex.org/C2775862500","wikidata":"https://www.wikidata.org/wiki/Q2453464","display_name":"Colitis","level":2,"score":0.41331779956817627},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38907766342163086},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.12810230255126953}],"mesh":[{"descriptor_ui":"D000068879","descriptor_name":"Adalimumab","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069285","descriptor_name":"Infliximab","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005765","descriptor_name":"Gastrointestinal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005765","descriptor_name":"Gastrointestinal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010950","descriptor_name":"Plasma Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012809","descriptor_name":"Colon, Sigmoid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012809","descriptor_name":"Colon, Sigmoid","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018655","descriptor_name":"Lymphocyte Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D061067","descriptor_name":"Antibodies, Monoclonal, Humanized","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/ecco-jcc/jjaa178","doi":"https://doi.org/10.1093/ecco-jcc/jjaa178","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ecco-jcc/jjaa178","pdf_url":"https://academic.oup.com/ecco-jcc/article-pdf/15/3/441/36463160/jjaa178.pdf","source":{"id":"https://openalex.org/S2735960814","display_name":"Journal of Crohn s and Colitis","issn_l":"1873-9946","issn":["1873-9946","1876-4479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Crohn's and Colitis","raw_type":"journal-article"},{"id":"pmid:32926095","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32926095","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Crohn's & colitis","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7944518","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7944518/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Crohns Colitis","raw_type":"Text"},{"id":"pmh:oai:diposit.ub.edu:2445/177748","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2445/177748","pdf_url":null,"source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Articles publicats en revistes (Medicina)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/ecco-jcc/jjaa178","doi":"https://doi.org/10.1093/ecco-jcc/jjaa178","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ecco-jcc/jjaa178","pdf_url":"https://academic.oup.com/ecco-jcc/article-pdf/15/3/441/36463160/jjaa178.pdf","source":{"id":"https://openalex.org/S2735960814","display_name":"Journal of Crohn s and Colitis","issn_l":"1873-9946","issn":["1873-9946","1876-4479"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Crohn's and Colitis","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4765957166","display_name":null,"funder_award_id":"2017SGR-992","funder_id":"https://openalex.org/F4320334830","funder_display_name":"Ag\u00e8ncia de Gesti\u00f3 d'Ajuts Universitaris i de Recerca"}],"funders":[{"id":"https://openalex.org/F4320321505","display_name":"Generalitat de Catalunya","ror":"https://ror.org/01bg62x04"},{"id":"https://openalex.org/F4320329144","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas","ror":"https://ror.org/03cn6tr16"},{"id":"https://openalex.org/F4320334830","display_name":"Ag\u00e8ncia de Gesti\u00f3 d'Ajuts Universitaris i de Recerca","ror":"https://ror.org/01n4pqe45"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3085772379.pdf","grobid_xml":"https://content.openalex.org/works/W3085772379.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1483614591","https://openalex.org/W1549164741","https://openalex.org/W1622884606","https://openalex.org/W1937497737","https://openalex.org/W1970379493","https://openalex.org/W1972137791","https://openalex.org/W1978187637","https://openalex.org/W1986775143","https://openalex.org/W1986834440","https://openalex.org/W1991865241","https://openalex.org/W1993531725","https://openalex.org/W2000069945","https://openalex.org/W2001452004","https://openalex.org/W2046234296","https://openalex.org/W2047977785","https://openalex.org/W2067194679","https://openalex.org/W2068583880","https://openalex.org/W2082595913","https://openalex.org/W2085875957","https://openalex.org/W2096515408","https://openalex.org/W2098574033","https://openalex.org/W2101950619","https://openalex.org/W2102116540","https://openalex.org/W2113168577","https://openalex.org/W2120522488","https://openalex.org/W2126088081","https://openalex.org/W2137630301","https://openalex.org/W2146692972","https://openalex.org/W2150140226","https://openalex.org/W2160619682","https://openalex.org/W2162805528","https://openalex.org/W2168654564","https://openalex.org/W2171297959","https://openalex.org/W2321205867","https://openalex.org/W2515435336","https://openalex.org/W2532628390","https://openalex.org/W2611548364","https://openalex.org/W2741581932","https://openalex.org/W2773289068","https://openalex.org/W2774359923","https://openalex.org/W2774927467","https://openalex.org/W2794186149","https://openalex.org/W2801753207","https://openalex.org/W2808336191","https://openalex.org/W2809500715","https://openalex.org/W2886879561","https://openalex.org/W2895526782","https://openalex.org/W2903889319","https://openalex.org/W2912982848","https://openalex.org/W2913992246","https://openalex.org/W2946468288","https://openalex.org/W2969631216","https://openalex.org/W3000586022","https://openalex.org/W3008907392","https://openalex.org/W4210662453","https://openalex.org/W4313169499","https://openalex.org/W6632959994","https://openalex.org/W6728314626"],"related_works":["https://openalex.org/W4318577214","https://openalex.org/W4394951011","https://openalex.org/W2914193478","https://openalex.org/W2886879561","https://openalex.org/W4387638036","https://openalex.org/W7127335269","https://openalex.org/W4391162765","https://openalex.org/W2591742226","https://openalex.org/W4378363671","https://openalex.org/W7125429423"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"AIMS:":[2],"Vedolizumab":[3],"is":[4,18],"an":[5],"anti-\u03b14\u03b27":[6],"antibody":[7],"approved":[8],"for":[9,112],"the":[10,42,131,142,156,174,187,203,231],"treatment":[11],"of":[12,25,45,47,133,144,158,176,189,205,237,244],"ulcerative":[13],"colitis":[14],"[UC].":[15],"Although":[16],"it":[17],"assumed":[19],"that":[20,216,256],"vedolizumab":[21,48,74,166,218],"blocks":[22],"intestinal":[23,31,137,209,242],"homing":[24],"lymphocytes,":[26],"its":[27,54],"effects":[28,55],"on":[29,240],"different":[30],"cell":[32,113],"populations":[33],"are":[34],"not":[35,154,192],"fully":[36],"stablished.":[37],"In":[38],"order":[39],"to":[40,56,119,127,251],"establish":[41],"unique":[43,235],"mechanisms":[44],"action":[46,238],"in":[49,125,151,173],"UC":[50,68],"patients,":[51],"we":[52],"compared":[53],"those":[57],"induced":[58],"by":[59],"anti-tumour":[60],"necrosis":[61],"factor":[62],"[TNF].":[63],"METHODS:":[64],"Patients":[65],"with":[66],"active":[67],"[endoscopic":[69],"Mayo":[70],"score":[71,179],">1]":[72],"starting":[73],"[n":[75,80,85],"=":[76,81,86],"33]":[77],"or":[78],"anti-TNF":[79,168,220],"45]":[82],"and":[83,96,98,108,118,167,197,219,253],"controls":[84],"22]":[87],"were":[88,110],"included.":[89],"Colon":[90],"biopsies":[91],"[at":[92,101,162],"weeks":[93,102],"0,":[94,103],"14":[95],"46]":[97,109],"blood":[99],"samples":[100],"2,":[104],"6,":[105],"14,":[106],"30":[107],"used":[111],"phenotyping,":[114],"transcriptional":[115],"analysis":[116],"[qPCR],":[117],"measure":[120],"receptor":[121],"occupancy.":[122],"RESULTS:":[123],"Vedolizumab,":[124],"contrast":[126],"anti-TNF,":[128],"significantly":[129,169,185],"reduced":[130],"proportion":[132,204],"\u03b14\u03b27+":[134,145],"cells":[135,161,207,255],"within":[136,208],"T":[138,210,246],"subsets":[139],"while":[140,217],"preserving":[141],"percentage":[143,157,188],"plasma":[146,198,254],"cells.":[147],"The":[148],"marked":[149],"decrease":[150],"\u03b14\u03b27":[152,245],"did":[153],"change":[155],"colonic":[159],"\u03b1E\u03b27+":[160],"46":[163],"weeks].":[164],"Both":[165],"downregulated":[170],"inflammation-related":[171],"genes":[172],"colon":[175],"responders":[177],"[Mayo":[178],"<":[180],"2].":[181],"Moreover,":[182],"both":[183],"treatments":[184],"decreased":[186],"intestinal,":[190],"but":[191],"blood,":[193],"total":[194],"lymphocytes":[195],"[T":[196],"cells],":[199],"as":[200,202],"well":[201],"\u03b14\u03b21+":[206],"lymphocytes.":[211],"CONCLUSIONS:":[212],"Our":[213],"data":[214],"show":[215],"block":[221],"two":[222],"unrelated":[223],"targets,":[224],"they":[225],"induce":[226],"remarkably":[227],"similar":[228],"effects.":[229],"On":[230],"other":[232],"hand,":[233],"vedolizumab's":[234],"mechanism":[236],"relies":[239],"blocking":[241],"trafficking":[243],"cells,":[247],"despite":[248],"effectively":[249],"binding":[250],"B":[252],"express":[257],"\u03b14\u03b27.":[258]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2020-09-21T00:00:00"}