{"id":"https://openalex.org/W3085039775","doi":"https://doi.org/10.21037/jtd-2019-rbmlc-06","title":"WBRT for brain metastases from non-small cell lung cancer: for whom and when?\u2014Contemporary point of view","display_name":"WBRT for brain metastases from non-small cell lung cancer: for whom and when?\u2014Contemporary point of view","publication_year":2021,"publication_date":"2021-05-01","ids":{"openalex":"https://openalex.org/W3085039775","doi":"https://doi.org/10.21037/jtd-2019-rbmlc-06","mag":"3085039775","pmid":"https://pubmed.ncbi.nlm.nih.gov/34164217","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8182552"},"language":"en","primary_location":{"id":"doi:10.21037/jtd-2019-rbmlc-06","doi":"https://doi.org/10.21037/jtd-2019-rbmlc-06","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd-2019-rbmlc-06","pdf_url":"https://jtd.amegroups.com/article/viewFile/43985/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jtd.amegroups.com/article/viewFile/43985/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020307855","display_name":"Beata Sas-Korczy\u0144ska","orcid":"https://orcid.org/0000-0002-4895-0414","observed_orcids":["https://orcid.org/0000-0002-4895-0414"]},"institutions":[{"id":"https://openalex.org/I4210146974","display_name":"Wojskowy Instytut Medyczny","ror":"https://ror.org/04zvqhj72","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210146974"]},{"id":"https://openalex.org/I98559091","display_name":"University of Rzesz\u00f3w","ror":"https://ror.org/03pfsnq21","country_code":"PL","type":"education","lineage":["https://openalex.org/I98559091"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Beata Sas-Korczynska","raw_affiliation_strings":["Department of Radiotherapy, Military Institute of Medicine, Warsaw, Poland","Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, Military Institute of Medicine, Warsaw, Poland","institution_ids":["https://openalex.org/I4210146974"]},{"raw_affiliation_string":"Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland","institution_ids":["https://openalex.org/I98559091"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022675366","display_name":"Monika Ruci\u0144ska","orcid":"https://orcid.org/0000-0002-1975-0624","observed_orcids":["https://orcid.org/0000-0002-1975-0624"]},"institutions":[{"id":"https://openalex.org/I4210146974","display_name":"Wojskowy Instytut Medyczny","ror":"https://ror.org/04zvqhj72","country_code":"PL","type":"healthcare","lineage":["https://openalex.org/I4210146974"]},{"id":"https://openalex.org/I47996466","display_name":"University of Warmia and Mazury in Olsztyn","ror":"https://ror.org/05s4feg49","country_code":"PL","type":"education","lineage":["https://openalex.org/I47996466"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Monika Rucinska","raw_affiliation_strings":["Department of Oncology, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland","Department of Radiotherapy, Military Institute of Medicine, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland","institution_ids":["https://openalex.org/I47996466"]},{"raw_affiliation_string":"Department of Radiotherapy, Military Institute of Medicine, Warsaw, Poland","institution_ids":["https://openalex.org/I4210146974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5020307855"],"corresponding_institution_ids":["https://openalex.org/I4210146974","https://openalex.org/I98559091"],"apc_list":null,"apc_paid":null,"fwci":0.3788,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.39712863,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"5","first_page":"3246","last_page":"3257"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/whole-brain-radiotherapy","display_name":"whole brain radiotherapy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/brain-metastases","display_name":"brain metastases","score":0.9940000176429749},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":1.0},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7039999961853027},{"id":"https://openalex.org/keywords/stereotactic-radiosurgery","display_name":"stereotactic radiosurgery","score":0.9129999876022339},{"id":"https://openalex.org/keywords/surgical-resection","display_name":"surgical resection","score":0.7940000295639038},{"id":"https://openalex.org/keywords/eml4-alk-fusion","display_name":"EML4-ALK fusion","score":0.9290000200271606},{"id":"https://openalex.org/keywords/crizotinib","display_name":"crizotinib","score":0.9990000128746033},{"id":"https://openalex.org/keywords/systemic-treatment","display_name":"systemic therapy","score":0.6510000228881836},{"id":"https://openalex.org/keywords/best-supportive-care","display_name":"best supportive care","score":0.753000020980835},{"id":"https://openalex.org/keywords/treatment-decision-making","display_name":"treatment decision-making","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.956668496131897},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.719811201095581},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.7043255567550659},{"id":"https://openalex.org/C185926286","wikidata":"https://www.wikidata.org/wiki/Q1929812","display_name":"Systemic therapy","level":4,"score":0.5250066518783569},{"id":"https://openalex.org/C2779177807","wikidata":"https://www.wikidata.org/wiki/Q3658562","display_name":"non-small cell lung cancer (NSCLC)","level":4,"score":0.4971349537372589},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.48644423484802246},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4736301302909851},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4297240376472473},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41526609659194946},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3258311450481415},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.1443864107131958},{"id":"https://openalex.org/C81729549","wikidata":"https://www.wikidata.org/wiki/Q4649475","display_name":"A549 cell","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.21037/jtd-2019-rbmlc-06","doi":"https://doi.org/10.21037/jtd-2019-rbmlc-06","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd-2019-rbmlc-06","pdf_url":"https://jtd.amegroups.com/article/viewFile/43985/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},{"id":"pmid:34164217","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34164217","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of thoracic disease","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8182552","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8182552/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Thorac Dis","raw_type":"Text"},{"id":"pmh:oai:ruj.uj.edu.pl:item/290376","doi":null,"is_oa":true,"landing_page_url":"https://jtd.amegroups.com/article/view/43985/html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400316","display_name":"Homo Politicus (Academy of Humanities and Economics in Lodz)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"artyku\u0142 w czasopi\u015bmie"}],"best_oa_location":{"id":"doi:10.21037/jtd-2019-rbmlc-06","doi":"https://doi.org/10.21037/jtd-2019-rbmlc-06","is_oa":true,"landing_page_url":"https://doi.org/10.21037/jtd-2019-rbmlc-06","pdf_url":"https://jtd.amegroups.com/article/viewFile/43985/pdf","source":{"id":"https://openalex.org/S2754193772","display_name":"Journal of Thoracic Disease","issn_l":"2072-1439","issn":["2072-1439","2077-6624"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321814","host_organization_name":"AME Publishing Company","host_organization_lineage":["https://openalex.org/P4310321814"],"host_organization_lineage_names":["AME Publishing Company"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thoracic Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3085039775.pdf","grobid_xml":"https://content.openalex.org/works/W3085039775.grobid-xml"},"referenced_works_count":106,"referenced_works":["https://openalex.org/W148295428","https://openalex.org/W150263754","https://openalex.org/W1583938132","https://openalex.org/W1642085743","https://openalex.org/W1885234230","https://openalex.org/W1902158572","https://openalex.org/W1922266404","https://openalex.org/W1964127544","https://openalex.org/W1964905218","https://openalex.org/W1974820090","https://openalex.org/W1977413081","https://openalex.org/W1980240684","https://openalex.org/W1982293981","https://openalex.org/W1984371963","https://openalex.org/W1985776651","https://openalex.org/W1995174703","https://openalex.org/W2002859650","https://openalex.org/W2004852620","https://openalex.org/W2011670622","https://openalex.org/W2013070755","https://openalex.org/W2016908822","https://openalex.org/W2021478257","https://openalex.org/W2025727766","https://openalex.org/W2035712312","https://openalex.org/W2035982498","https://openalex.org/W2037550193","https://openalex.org/W2038247960","https://openalex.org/W2038639693","https://openalex.org/W2039202448","https://openalex.org/W2040059131","https://openalex.org/W2047930883","https://openalex.org/W2048233250","https://openalex.org/W2050249255","https://openalex.org/W2061962226","https://openalex.org/W2062107475","https://openalex.org/W2069419936","https://openalex.org/W2080201870","https://openalex.org/W2083854495","https://openalex.org/W2089422620","https://openalex.org/W2098677385","https://openalex.org/W2102149158","https://openalex.org/W2107529266","https://openalex.org/W2109986616","https://openalex.org/W2111662961","https://openalex.org/W2113465576","https://openalex.org/W2114464493","https://openalex.org/W2121625197","https://openalex.org/W2123101598","https://openalex.org/W2128871519","https://openalex.org/W2130156047","https://openalex.org/W2131359324","https://openalex.org/W2132495825","https://openalex.org/W2135121296","https://openalex.org/W2141307029","https://openalex.org/W2143843774","https://openalex.org/W2145963430","https://openalex.org/W2147038864","https://openalex.org/W2153022133","https://openalex.org/W2153979476","https://openalex.org/W2154704485","https://openalex.org/W2155073814","https://openalex.org/W2158757066","https://openalex.org/W2158789700","https://openalex.org/W2162065895","https://openalex.org/W2163367216","https://openalex.org/W2165459839","https://openalex.org/W2177244913","https://openalex.org/W2320854978","https://openalex.org/W2329720070","https://openalex.org/W2329793926","https://openalex.org/W2397063676","https://openalex.org/W2442259061","https://openalex.org/W2464028256","https://openalex.org/W2492450141","https://openalex.org/W2510132475","https://openalex.org/W2512513150","https://openalex.org/W2533301708","https://openalex.org/W2545809529","https://openalex.org/W2555516405","https://openalex.org/W2570618306","https://openalex.org/W2588156728","https://openalex.org/W2616133171","https://openalex.org/W2661050784","https://openalex.org/W2724926078","https://openalex.org/W2726463501","https://openalex.org/W2731821507","https://openalex.org/W2738653255","https://openalex.org/W2743773854","https://openalex.org/W2745107466","https://openalex.org/W2761837486","https://openalex.org/W2786709615","https://openalex.org/W2801437319","https://openalex.org/W2896214448","https://openalex.org/W2904164797","https://openalex.org/W2908852422","https://openalex.org/W2912079172","https://openalex.org/W2921097668","https://openalex.org/W2925213523","https://openalex.org/W2946052973","https://openalex.org/W3015469897","https://openalex.org/W4212848069","https://openalex.org/W4231411933","https://openalex.org/W4234678854","https://openalex.org/W4242436934","https://openalex.org/W4244111797","https://openalex.org/W6828268632"],"related_works":["https://openalex.org/W3103825619","https://openalex.org/W2558612843","https://openalex.org/W1506255673","https://openalex.org/W2132771960","https://openalex.org/W2738653255","https://openalex.org/W4385810182","https://openalex.org/W2588550132","https://openalex.org/W2790785592","https://openalex.org/W2587374475","https://openalex.org/W2801739013"],"abstract_inverted_index":{"Abstract:":[0],"The":[1,18,47,66,119],"incidence":[2],"of":[3,13,22,42,50,63,71,103,121,124,150,152,169,208,228,245],"brain":[4,77],"metastases":[5],"(BM)":[6],"is":[7,25,81,111,126,213],"estimated":[8],"between":[9,159],"20%":[10],"and":[11,28,97,139,166,239,262],"40%":[12],"patients":[14,106,131,235,242,258],"with":[15,107,116,132,173,184,236,243,250,259],"solid":[16],"cancer.":[17],"most":[19,196],"common":[20,40],"cause":[21],"this":[23],"failure":[24],"lung":[26,34,232],"cancer,":[27],"in":[29,44,114,154,171,226,234,240,241,257],"locally":[30],"advanced":[31],"non-small":[32],"cell":[33],"cancer":[35,233],"(NSCLC)":[36],"BM":[37,72,133,230],"represent":[38],"a":[39,209],"site":[41],"relapse":[43],"30\u201355%":[45],"cases.":[46],"basic":[48],"criteria":[49],"therapeutic":[51],"decision-making":[52],"are":[53,61],"based":[54,217],"on":[55,218],"the":[56,100,148,162,195,206,214,219],"significant":[57],"prognostic":[58,64],"factors":[59],"which":[60,80,130],"components":[62],"scores.":[65],"standard":[67],"approach":[68],"to":[69,128,156,188,201],"treatment":[70,96,104,175,227],"from":[73,134,190,231],"NSCLC":[74,135],"include":[75],"whole":[76],"radiotherapy":[78],"(WBRT)":[79],"used":[82,113],"as":[83,94],"adjuvant":[84],"modality":[85,102],"after":[86,263],"local":[87,174],"therapy":[88,249],"(surgery":[89],"or":[90,93,161,179],"stereotactic":[91,180],"radiosurgery)":[92],"primary":[95,101,264],"it":[98,141],"remains":[99],"for":[105,211],"multiple":[108,229],"metastases.":[109],"WBRT":[110,138,153,160,170,212,222,253],"also":[112],"combination":[115,172],"systemic":[117,185],"therapy.":[118,186],"aim":[120],"presented":[122,147],"review":[123],"literature":[125,191],"trying":[127],"answer":[129],"should":[136,223],"receive":[137],"when":[140,204],"could":[142,254],"be":[143,202,224,255],"omitted.":[144],"There":[145],"were":[146],"aspects":[149],"application":[151],"relation":[155],"(I)":[157],"choice":[158],"best":[163],"supportive":[164],"care":[165],"(II)":[167],"employment":[168],"modalities":[176],"[surgical":[177],"resection":[178],"radio-surgery":[181],"(SRS)]":[182],"and/or":[183],"According":[187],"data":[189],"we":[192],"concluded":[193],"that":[194,199],"important":[197],"factor":[198],"needs":[200],"considered":[203],"assessing":[205],"suitability":[207],"patient":[210],"patient\u2019s":[215],"prognosis":[216,238,261],"Lung-molGPA":[220],"score.":[221],"applied":[225],"favourable":[237],"presence":[244],"EML4-ALK":[246],"translocation":[247],"before":[248],"crizotinib.":[251],"Whereas":[252],"omitted":[256],"poor":[260],"SRS.":[265]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2020-09-21T00:00:00"}
