{"id":"https://openalex.org/W3084045488","doi":"https://doi.org/10.1039/d0ay01535k","title":"Determination of 4 psychoactive substances in tea using ultra high performance liquid chromatography combined with the quadrupole time-of-flight mass spectrometry","display_name":"Determination of 4 psychoactive substances in tea using ultra high performance liquid chromatography combined with the quadrupole time-of-flight mass spectrometry","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3084045488","doi":"https://doi.org/10.1039/d0ay01535k","mag":"3084045488","pmid":"https://pubmed.ncbi.nlm.nih.gov/32966359"},"language":"en","primary_location":{"id":"doi:10.1039/d0ay01535k","doi":"https://doi.org/10.1039/d0ay01535k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d0ay01535k","pdf_url":null,"source":{"id":"https://openalex.org/S170358085","display_name":"Analytical Methods","issn_l":"1759-9660","issn":["1759-9660","1759-9679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Methods","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100694102","display_name":"Jian Li","orcid":"https://orcid.org/0000-0003-0987-118X","observed_orcids":["https://orcid.org/0000-0003-0987-118X"]},"institutions":[{"id":"https://openalex.org/I114234892","display_name":"Beijing Union University","ror":"https://ror.org/01hg31662","country_code":"CN","type":"education","lineage":["https://openalex.org/I114234892"]},{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Li","raw_affiliation_strings":["China","College of Applied Arts and Science","Hefei 230009","Hefei University of Technology","School of Food and Biological Engineering","College of Applied Arts and Science, Beijing Union University, Beijing 100191, China","School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China"],"raw_orcid":"https://orcid.org/0000-0003-0987-118X","affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"College of Applied Arts and Science","institution_ids":[]},{"raw_affiliation_string":"Hefei 230009","institution_ids":[]},{"raw_affiliation_string":"Hefei University of Technology","institution_ids":["https://openalex.org/I16365422"]},{"raw_affiliation_string":"School of Food and Biological Engineering","institution_ids":[]},{"raw_affiliation_string":"College of Applied Arts and Science, Beijing Union University, Beijing 100191, China","institution_ids":["https://openalex.org/I114234892"]},{"raw_affiliation_string":"School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China","institution_ids":["https://openalex.org/I16365422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030397772","display_name":"Junmei Ma","orcid":"https://orcid.org/0000-0001-8004-1440","observed_orcids":["https://orcid.org/0000-0001-8004-1440"]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210122129","display_name":"Hebei Food Inspection and Research Institute","ror":"https://ror.org/02pxntn72","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210122129"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junmei Ma","raw_affiliation_strings":["China","College of Forensic Medicine","Hebei Key Laboratory of Forensic Medicine","Hebei Medical University","Shijiazhuang 050017","Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute, Shijiazhuang 050227, China","Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang 050017, China"],"raw_orcid":"https://orcid.org/0000-0001-8004-1440","affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"College of Forensic Medicine","institution_ids":[]},{"raw_affiliation_string":"Hebei Key Laboratory of Forensic Medicine","institution_ids":[]},{"raw_affiliation_string":"Hebei Medical University","institution_ids":["https://openalex.org/I111381250"]},{"raw_affiliation_string":"Shijiazhuang 050017","institution_ids":[]},{"raw_affiliation_string":"Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute, Shijiazhuang 050227, China","institution_ids":["https://openalex.org/I4210122129"]},{"raw_affiliation_string":"Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang 050017, China","institution_ids":["https://openalex.org/I111381250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456227","display_name":"Yan Zhang","orcid":"https://orcid.org/0000-0002-2947-1629","observed_orcids":["https://orcid.org/0000-0002-2947-1629"]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210122129","display_name":"Hebei Food Inspection and Research Institute","ror":"https://ror.org/02pxntn72","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210122129"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["China","College of Forensic Medicine","Hebei Key Laboratory of Forensic Medicine","Hebei Medical University","Shijiazhuang 050017","Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute, Shijiazhuang 050227, China","Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang 050017, China"],"raw_orcid":"https://orcid.org/0000-0002-2947-1629","affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"College of Forensic Medicine","institution_ids":[]},{"raw_affiliation_string":"Hebei Key Laboratory of Forensic Medicine","institution_ids":[]},{"raw_affiliation_string":"Hebei Medical University","institution_ids":["https://openalex.org/I111381250"]},{"raw_affiliation_string":"Shijiazhuang 050017","institution_ids":[]},{"raw_affiliation_string":"Hebei Food Safety Key Laboratory, Hebei Food Inspection and Research Institute, Shijiazhuang 050227, China","institution_ids":["https://openalex.org/I4210122129"]},{"raw_affiliation_string":"Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang 050017, China","institution_ids":["https://openalex.org/I111381250"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100783398","display_name":"Lei Zheng","orcid":"https://orcid.org/0000-0001-8367-5502","observed_orcids":["https://orcid.org/0000-0001-8367-5502","https://orcid.org/0000-0001-6222-2344"]},"institutions":[{"id":"https://openalex.org/I16365422","display_name":"Hefei University of Technology","ror":"https://ror.org/02czkny70","country_code":"CN","type":"education","lineage":["https://openalex.org/I16365422"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lei Zheng","raw_affiliation_strings":["China","Hefei 230009","Hefei University of Technology","School of Food and Biological Engineering","School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China"],"raw_orcid":"https://orcid.org/0000-0001-8367-5502","affiliations":[{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Hefei 230009","institution_ids":[]},{"raw_affiliation_string":"Hefei University of Technology","institution_ids":["https://openalex.org/I16365422"]},{"raw_affiliation_string":"School of Food and Biological Engineering","institution_ids":[]},{"raw_affiliation_string":"School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China","institution_ids":["https://openalex.org/I16365422"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100456227","https://openalex.org/A5100783398"],"corresponding_institution_ids":["https://openalex.org/I111381250","https://openalex.org/I16365422","https://openalex.org/I4210122129"],"apc_list":null,"apc_paid":null,"fwci":1.2178,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.72538059,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"12","issue":"40","first_page":"4878","last_page":"4884"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11423","display_name":"Pesticide Residue Analysis and Safety","score":0.05400000140070915,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13079","display_name":"Heavy Metals in Plants","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psychoactive-substances","display_name":"psychoactive substances","score":0.890999972820282},{"id":"https://openalex.org/keywords/tea","display_name":"tea","score":0.9890000224113464},{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.5540000200271606},{"id":"https://openalex.org/keywords/theobromine","display_name":"theobromine","score":0.7860000133514404},{"id":"https://openalex.org/keywords/theophylline","display_name":"theophylline","score":0.7910000085830688},{"id":"https://openalex.org/keywords/methylxanthines","display_name":"methylxanthines","score":0.6880000233650208},{"id":"https://openalex.org/keywords/uplc-q-tof-ms","display_name":"UPLC-Q-TOF-MS","score":0.8640000224113464},{"id":"https://openalex.org/keywords/data-dependent-acquisition","display_name":"data-dependent acquisition","score":0.8019999861717224},{"id":"https://openalex.org/keywords/food-contamination-detection","display_name":"food contaminant detection","score":0.5170000195503235},{"id":"https://openalex.org/keywords/method-validation","display_name":"method validation","score":0.41200000047683716}],"concepts":[{"id":"https://openalex.org/C3019798703","wikidata":"https://www.wikidata.org/wiki/Q5953256","display_name":"Quadrupole time of flight","level":4,"score":0.9714367985725403},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7753221988677979},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.7744452953338623},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6929596066474915},{"id":"https://openalex.org/C39984356","wikidata":"https://www.wikidata.org/wiki/Q2121987","display_name":"Quadrupole","level":2,"score":0.6460753679275513},{"id":"https://openalex.org/C16291436","wikidata":"https://www.wikidata.org/wiki/Q874402","display_name":"Time-of-flight mass spectrometry","level":4,"score":0.5405174493789673},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.48233386874198914},{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.1813172698020935},{"id":"https://openalex.org/C198291218","wikidata":"https://www.wikidata.org/wiki/Q190382","display_name":"Ionization","level":3,"score":0.0560242235660553},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.055229783058166504},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.04884970188140869},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.0},{"id":"https://openalex.org/C184779094","wikidata":"https://www.wikidata.org/wiki/Q26383","display_name":"Atomic physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013662","descriptor_name":"Tea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053719","descriptor_name":"Tandem Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1039/d0ay01535k","doi":"https://doi.org/10.1039/d0ay01535k","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d0ay01535k","pdf_url":null,"source":{"id":"https://openalex.org/S170358085","display_name":"Analytical Methods","issn_l":"1759-9660","issn":["1759-9660","1759-9679"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Methods","raw_type":"journal-article"},{"id":"pmid:32966359","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32966359","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical methods : advancing methods and applications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.428600013256073,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1166861835","display_name":null,"funder_award_id":"2018YFC1603400","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1561999991","https://openalex.org/W2011747206","https://openalex.org/W2024058930","https://openalex.org/W2059628030","https://openalex.org/W2087969824","https://openalex.org/W2089868622","https://openalex.org/W2296510325","https://openalex.org/W2525814115","https://openalex.org/W2761287864","https://openalex.org/W2775705763","https://openalex.org/W2801251843","https://openalex.org/W2804362963","https://openalex.org/W2807892298","https://openalex.org/W2885960307","https://openalex.org/W2891980244","https://openalex.org/W2938865378","https://openalex.org/W2951397282","https://openalex.org/W2970803900","https://openalex.org/W2973377525","https://openalex.org/W2973873071","https://openalex.org/W2979891205","https://openalex.org/W3005357648","https://openalex.org/W3015650736","https://openalex.org/W3017587445","https://openalex.org/W3033241629","https://openalex.org/W3040547899"],"related_works":["https://openalex.org/W4210427004","https://openalex.org/W2140308276","https://openalex.org/W2355457842","https://openalex.org/W4383751022","https://openalex.org/W2987641596","https://openalex.org/W6885383744","https://openalex.org/W2291600963","https://openalex.org/W6941787901","https://openalex.org/W6921505454","https://openalex.org/W1981977836"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"a":[3,38,55,95],"method":[4,140,162],"for":[5,173],"the":[6,24,79,84,102,119,126,130,139,174],"qualification":[7],"and":[8,43,70,94,108,125,153,166],"quantification":[9],"of":[10,83,104,121,132,138,144,149,176],"4":[11,85,177],"psychoactive":[12,86,178],"substances":[13,87,179],"in":[14,68,101,118,129,142,180],"tea":[15,181],"using":[16,54],"ultra":[17],"high":[18],"performance":[19],"liquid":[20],"chromatography":[21],"coupled":[22],"with":[23,146],"quadrupole":[25],"time-of-flight":[26],"mass":[27,80],"spectrometry":[28],"(UPLC-Q-TOF/MS)":[29],"has":[30,169],"been":[31,170],"developed.":[32],"Tea":[33],"samples":[34],"were":[35,64,88,157],"extracted":[36],"by":[37,46,59,66],"50%":[39],"(v/v)":[40],"methanol-water":[41],"solution,":[42],"then":[44],"separated":[45],"an":[47],"ACQUITY":[48],"UPLC":[49],"BEH":[50],"Shield":[51],"RP18":[52],"column":[53],"binary":[56],"solvent":[57],"system":[58],"gradient":[60],"elution.":[61],"The":[62,75,115,136,161],"analytes":[63],"determined":[65],"Q-TOF/MS":[67],"TOFMS":[69],"information-dependent":[71],"acquisition":[72],"(IDA)-MS/MS":[73],"mode.":[74],"results":[76],"showed":[77],"that":[78],"accuracy":[81],"error":[82],"lower":[89,158],"than":[90,113,159],"5.0":[91],"\u00d7":[92],"10-6,":[93],"good":[96],"linear":[97],"relationship":[98],"was":[99,111,117,128,141,163],"observed":[100],"range":[103,120,131,143],"0.5-500":[105],"\u03bcg":[106],"L-1":[107],"correlation":[109],"coefficient":[110],"higher":[112],"0.9990.":[114],"LOD":[116],"0.005-0.020":[122],"mg":[123,134,151],"kg-1":[124],"LOQ":[127],"0.010-0.040":[133],"kg-1.":[135],"recovery":[137],"80.14-93.25%":[145],"spike":[147],"levels":[148],"0.010-0.400":[150],"kg-1,":[152],"relative":[154],"standard":[155],"deviations":[156],"10%.":[160],"simple,":[164],"specific":[165],"reliable.":[167],"It":[168],"successfully":[171],"used":[172],"detection":[175],"samples.":[182]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2020-09-14T00:00:00"}