{"id":"https://openalex.org/W3083387372","doi":"https://doi.org/10.1158/1538-7445.am2020-1678","title":"Abstract 1678: Establishment and characterization by expression microarrays of a patient-derived xenograft biobank for human pancreatic adenocarcinoma","display_name":"Abstract 1678: Establishment and characterization by expression microarrays of a patient-derived xenograft biobank for human pancreatic adenocarcinoma","publication_year":2020,"publication_date":"2020-08-15","ids":{"openalex":"https://openalex.org/W3083387372","doi":"https://doi.org/10.1158/1538-7445.am2020-1678","mag":"3083387372"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am2020-1678","doi":"https://doi.org/10.1158/1538-7445.am2020-1678","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2020-1678","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080905361","display_name":"Sandra Roche","orcid":"https://orcid.org/0000-0002-4363-4607","observed_orcids":["https://orcid.org/0000-0002-4363-4607"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Sandra Roche","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101635609","display_name":"Fiona O\u2019Neill","orcid":"https://orcid.org/0000-0002-6935-5171","observed_orcids":["https://orcid.org/0000-0002-6935-5171"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Fiona O'Neill","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018769868","display_name":"Niall Swan","orcid":"https://orcid.org/0000-0003-2838-6972","observed_orcids":["https://orcid.org/0000-0003-2838-6972"]},"institutions":[{"id":"https://openalex.org/I4210115218","display_name":"St. Vincent's University Hospital","ror":"https://ror.org/029tkqm80","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210115218"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Niall Swan","raw_affiliation_strings":["2St Vincent's University Hospital, Dublin 4, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2St Vincent's University Hospital, Dublin 4, Ireland;","institution_ids":["https://openalex.org/I4210115218"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036973925","display_name":"Ninfa L. Straubinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ninfa L. Straubinger","raw_affiliation_strings":["3University at Buffalo, Buffalo, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University at Buffalo, Buffalo, NY","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081497371","display_name":"Neil T. Conlon","orcid":"https://orcid.org/0000-0001-5921-7114","observed_orcids":["https://orcid.org/0000-0001-5921-7114"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Neil T. Conlon","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112051765","display_name":"Jean Murphy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115218","display_name":"St. Vincent's University Hospital","ror":"https://ror.org/029tkqm80","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210115218"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Jean Murphy","raw_affiliation_strings":["2St Vincent's University Hospital, Dublin 4, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2St Vincent's University Hospital, Dublin 4, Ireland;","institution_ids":["https://openalex.org/I4210115218"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061493580","display_name":"Kevin Conlon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115218","display_name":"St. Vincent's University Hospital","ror":"https://ror.org/029tkqm80","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210115218"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Kevin Conlon","raw_affiliation_strings":["2St Vincent's University Hospital, Dublin 4, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2St Vincent's University Hospital, Dublin 4, Ireland;","institution_ids":["https://openalex.org/I4210115218"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006249276","display_name":"Ray McDermott","orcid":"https://orcid.org/0000-0002-8952-4315","observed_orcids":["https://orcid.org/0000-0002-8952-4315"]},"institutions":[{"id":"https://openalex.org/I4210115218","display_name":"St. Vincent's University Hospital","ror":"https://ror.org/029tkqm80","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210115218"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Ray McDermott","raw_affiliation_strings":["2St Vincent's University Hospital, Dublin 4, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2St Vincent's University Hospital, Dublin 4, Ireland;","institution_ids":["https://openalex.org/I4210115218"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003577346","display_name":"Justine Meiller","orcid":"https://orcid.org/0000-0002-2997-4007","observed_orcids":["https://orcid.org/0000-0002-2997-4007"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Justine Meiller","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042187551","display_name":"Justin Geoghegan","orcid":"https://orcid.org/0000-0003-0266-3732","observed_orcids":["https://orcid.org/0000-0003-0266-3732"]},"institutions":[{"id":"https://openalex.org/I4210115218","display_name":"St. Vincent's University Hospital","ror":"https://ror.org/029tkqm80","country_code":"IE","type":"healthcare","lineage":["https://openalex.org/I4210115218"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Justin Geoghegan","raw_affiliation_strings":["2St Vincent's University Hospital, Dublin 4, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2St Vincent's University Hospital, Dublin 4, Ireland;","institution_ids":["https://openalex.org/I4210115218"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109449097","display_name":"Michael J. Moriarty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Michael Moriarty","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057883761","display_name":"Robert M. Straubinger","orcid":"https://orcid.org/0000-0003-0870-9236","observed_orcids":["https://orcid.org/0000-0003-0870-9236"]},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Straubinger","raw_affiliation_strings":["3University at Buffalo, Buffalo, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University at Buffalo, Buffalo, NY","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077091444","display_name":"MARTIN M. CLYNES","orcid":"https://orcid.org/0000-0002-3093-8185","observed_orcids":["https://orcid.org/0000-0002-3093-8185"]},"institutions":[{"id":"https://openalex.org/I42934936","display_name":"Dublin City University","ror":"https://ror.org/04a1a1e81","country_code":"IE","type":"education","lineage":["https://openalex.org/I42934936"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Martin Clynes","raw_affiliation_strings":["1Dublin City University, Dublin 9, Ireland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dublin City University, Dublin 9, Ireland;","institution_ids":["https://openalex.org/I42934936"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"80","issue":"16_Supplement","first_page":"1678","last_page":"1678"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-ductal-adenocarcinoma","display_name":"pancreatic ductal adenocarcinoma","score":0.9589999914169312},{"id":"https://openalex.org/keywords/patient-derived-xenografts","display_name":"patient-derived xenografts","score":0.9229999780654907},{"id":"https://openalex.org/keywords/biobanks","display_name":"biobanks","score":0.8059999942779541},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.7950000166893005},{"id":"https://openalex.org/keywords/microrna-expression","display_name":"microRNA expression","score":0.6330000162124634},{"id":"https://openalex.org/keywords/tspan1","display_name":"TSPAN1","score":0.8420000076293945},{"id":"https://openalex.org/keywords/tpx2","display_name":"TPX2","score":1.0},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.37700000405311584},{"id":"https://openalex.org/keywords/cell-cycle-genes","display_name":"cell cycle genes","score":0.6710000038146973},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.4359999895095825},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.41100001335144043},{"id":"https://openalex.org/keywords/preclinical-models","display_name":"preclinical models","score":0.5680000185966492},{"id":"https://openalex.org/keywords/differential-gene-expression","display_name":"differential gene expression","score":0.6489999890327454},{"id":"https://openalex.org/keywords/ireland","display_name":"Ireland","score":0.30799999833106995},{"id":"https://openalex.org/keywords/microtubule-associated-proteins","display_name":"microtubule-associated proteins","score":0.7200000286102295},{"id":"https://openalex.org/keywords/tumor-proliferation-marker","display_name":"tumor proliferation marker","score":0.35899999737739563}],"concepts":[{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.7180075645446777},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.552311897277832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5262728929519653},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.4860563576221466},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.4745548367500305},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4741736650466919},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.469194620847702},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.4538794755935669},{"id":"https://openalex.org/C193270364","wikidata":"https://www.wikidata.org/wiki/Q17141925","display_name":"Tissue microarray","level":3,"score":0.4333474338054657},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.420169472694397},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.4159250557422638},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4002767503261566},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3837037682533264},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37393343448638916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31042182445526123},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2698379158973694},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09061792492866516}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am2020-1678","doi":"https://doi.org/10.1158/1538-7445.am2020-1678","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2020-1678","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2362764965","https://openalex.org/W2355155998","https://openalex.org/W2376247222","https://openalex.org/W1483316219","https://openalex.org/W2434122763","https://openalex.org/W2373568152","https://openalex.org/W2944056601","https://openalex.org/W2964766646","https://openalex.org/W2393814928","https://openalex.org/W2412341374"],"abstract_inverted_index":{"Abstract":[0],"Pancreatic":[1],"cancer":[2,25,44,73],"survival":[3,10],"rate":[4,11],"is":[5,26,47],"poor,":[6],"with":[7,65,140,333],"a":[8,210,239,260,291,310,377],"5-year":[9],"of":[12,17,28,98,102,142,193,213,217,221,284,319,323,376,388,392],"7%":[13],"in":[14,38,61,170,179,223,234,242,255,264,301],"the":[15,20,29,180,186,218,243,248,256,265,279,389,393],"Republic":[16],"Ireland.":[18],"Over":[19],"last":[21],"40":[22],"years,":[23],"pancreatic":[24,43,72,285,306,383],"one":[27],"only":[30,71],"solid":[31],"tumor":[32,120,127,144,171,187,267,299,326,328,335],"types":[33],"to":[34,49,159,174,185,247,269,277,297],"have":[35,68],"minimal":[36],"improvement":[37],"patient":[39,249,270,313],"outcome.":[40],"In":[41,63,163],"Ireland,":[42],"surgical":[45,85],"resection":[46,86],"limited":[48],"two":[50],"hospitals:":[51],"Cork":[52],"University":[53,58],"Hospital":[54,59],"and":[55,90,100,111,122,145,156,176,205,228,237,259,281,327,337,371,403],"St":[56],"Vincent's":[57],"(SVUH)":[60],"Dublin.":[62],"collaboration":[64],"SVUH,":[66],"we":[67,189],"established":[69],"Ireland's":[70],"patient-derived":[74,378],"xenograft":[75,379],"(PDX)":[76],"biobank":[77,308,380],"program.":[78],"Tumor":[79],"material":[80,106,121,128],"from":[81],"candidate":[82],"patients":[83],"following":[84],"was":[87,107,129,134,231,252],"cold":[88],"transferred":[89],"implanted":[91],"subcutaneously":[92],"into":[93],"CB17/Icr-Prkdcscid":[94],"mice.":[95],"At":[96],"time":[97],"implant":[99],"continuation":[101],"generations,":[103],"snap":[104],"frozen":[105],"collected.":[108],"Using":[109],"miRNA":[110],"mRNA":[112],"microarray":[113],"technology,":[114],"matched":[115],"adjacent":[116],"normal":[117,175,324],"tissue,":[118],"original":[119],"first":[123],"generation":[124],"(F1)":[125],"PDX":[126,181,244,266,307,330],"interrogated.":[130],"Differential":[131],"expression":[132,321,374],"analysis":[133,225],"carried":[135],"out":[136],"on":[137,165],"all":[138,149],"samples":[139,172,183],"comparisons":[141,150],"normal,":[143],"F1":[146,182,245],"generation.":[147],"Across":[148],"there":[151],"were":[152,168,226],"approximately":[153],"4000":[154],"genes":[155,166,192,220,332],"miRNAs":[157],"found":[158],"be":[160],"differential":[161],"expressed.":[162],"focusing":[164],"that":[167],"upregulated":[169,178,232,238,253],"compared":[173,184,246,268],"further":[177,240,261],"samples,":[188],"identified":[190],"88":[191],"interest.":[194],"Biological":[195],"processes":[196,204,208],"such":[197],"as":[198],"cell":[199,202,206,288],"division,":[200],"mitotic":[201],"cycle":[203,207],"characterized":[209],"significant":[211],"number":[212],"these":[214],"genes.":[215],"Two":[216],"key":[219],"interest":[222],"this":[224],"TSPAN1":[227,230,272],"TPX2.":[229],"9.5-fold":[233],"tumor-normal":[235,257],"comparison":[236,258],"2.3-fold":[241],"tumor.":[250,271],"TPX2":[251],"4.4-fold":[254],"3.9-fold":[262],"increase":[263,278],"has":[273,294],"previously":[274],"been":[275,295],"shown":[276,296],"metastatic":[280],"invasive":[282],"potential":[283],"ductal":[286],"adenocarcinoma":[287,384],"lines.":[289],"TPX2,":[290],"microtubule-associated":[292],"protein,":[293],"reduce":[298],"growth":[300],"vivo":[302],"when":[303],"silenced.":[304],"The":[305],"represents":[309],"versatile,":[311],"expandable":[312],"cohort":[314],"for":[315,381,396],"preclinical":[316],"investigation.":[317],"Analysis":[318],"gene":[320],"profiles":[322],"vs":[325],"Vs":[329],"showed":[331],"associated":[334],"proliferation":[336],"aggressiveness.":[338],"Citation":[339],"Format:":[340],"Sandra":[341],"Roche,":[342],"Fiona":[343],"O'Neill,":[344],"Niall":[345],"Swan,":[346],"Ninfa":[347],"L.":[348],"Straubinger,":[349,367],"Neil":[350],"T.":[351],"Conlon,":[352,356],"Jean":[353],"Murphy,":[354],"Kevin":[355],"Ray":[357],"McDermott,":[358],"Justine":[359],"Meiller,":[360],"Justin":[361],"Geoghegan,":[362],"Michael":[363],"Moriarty,":[364],"Robert":[365],"M.":[366],"Martin":[368],"Clynes.":[369],"Establishment":[370],"characterization":[372],"by":[373],"microarrays":[375],"human":[382],"[abstract].":[385],"In:":[386],"Proceedings":[387],"Annual":[390],"Meeting":[391],"American":[394],"Association":[395],"Cancer":[397,409],"Research":[398],"2020;":[399],"2020":[400],"Apr":[401],"27-28":[402],"Jun":[404],"22-24.":[405],"Philadelphia":[406],"(PA):":[407],"AACR;":[408],"Res":[410],"2020;80(16":[411],"Suppl):Abstract":[412],"nr":[413],"1678.":[414]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}