{"id":"https://openalex.org/W3083366983","doi":"https://doi.org/10.3892/ol.2020.12059","title":"MZB1 expression indicates poor prognosis in estrogen receptor\u2011positive breast cancer","display_name":"MZB1 expression indicates poor prognosis in estrogen receptor\u2011positive breast cancer","publication_year":2020,"publication_date":"2020-09-04","ids":{"openalex":"https://openalex.org/W3083366983","doi":"https://doi.org/10.3892/ol.2020.12059","mag":"3083366983","pmid":"https://pubmed.ncbi.nlm.nih.gov/32963604","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7491119"},"language":"en","primary_location":{"id":"doi:10.3892/ol.2020.12059","doi":"https://doi.org/10.3892/ol.2020.12059","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2020.12059","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2020.12059/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.spandidos-publications.com/10.3892/ol.2020.12059/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103399255","display_name":"Manabu Watanabe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Manabu Watanabe","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014646068","display_name":"Masahiro Shibata","orcid":"https://orcid.org/0000-0003-1028-2796","observed_orcids":["https://orcid.org/0000-0003-1028-2796"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Masahiro Shibata","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004655295","display_name":"Takahiro Inaishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiro Inaishi","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025864436","display_name":"Takahiro Ichikawa","orcid":"https://orcid.org/0000-0002-2545-5410","observed_orcids":["https://orcid.org/0000-0002-2545-5410"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiro Ichikawa","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087586489","display_name":"Ikumi Soeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ikumi Soeda","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109829239","display_name":"Noriyuki Miyajima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriyuki Miyajima","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012115431","display_name":"Yuko Takano","orcid":"https://orcid.org/0000-0002-3753-7683","observed_orcids":["https://orcid.org/0000-0002-3753-7683"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuko Takano","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112009859","display_name":"Dai Takeuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Dai Takeuchi","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066607030","display_name":"Nobuyuki Tsunoda","orcid":"https://orcid.org/0000-0002-4993-0028","observed_orcids":["https://orcid.org/0000-0002-4993-0028"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuyuki Tsunoda","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018268432","display_name":"Mitsuro Kanda","orcid":"https://orcid.org/0000-0001-5464-3819","observed_orcids":["https://orcid.org/0000-0001-5464-3819"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuro Kanda","raw_affiliation_strings":["Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026524817","display_name":"Toyone Kikumori","orcid":"https://orcid.org/0000-0003-3203-3766","observed_orcids":["https://orcid.org/0000-0003-3203-3766"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toyone Kikumori","raw_affiliation_strings":["Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018146056","display_name":"Yasuhiro Kodera","orcid":"https://orcid.org/0000-0002-6173-7474","observed_orcids":["https://orcid.org/0000-0002-6173-7474"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuhiro Kodera","raw_affiliation_strings":["Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101806827","display_name":"Masato Nagino","orcid":"https://orcid.org/0000-0002-8052-9902","observed_orcids":["https://orcid.org/0000-0002-8052-9902"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masato Nagino","raw_affiliation_strings":["Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466\u20118550, Japan","institution_ids":["https://openalex.org/I60134161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014646068"],"corresponding_institution_ids":["https://openalex.org/I60134161"],"apc_list":null,"apc_paid":null,"fwci":1.0024,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.69006744,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"20","issue":"5","first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mzb1","display_name":"MZB1","score":1.0},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8190000057220459},{"id":"https://openalex.org/keywords/estrogen-receptor-positive-breast-cancer","display_name":"estrogen receptor-positive breast cancer","score":0.9950000047683716},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9750000238418579},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9589999914169312},{"id":"https://openalex.org/keywords/tumor-stage","display_name":"tumor stage","score":0.8809999823570251},{"id":"https://openalex.org/keywords/unfolded-protein-response","display_name":"unfolded protein response","score":0.824999988079071},{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.7409999966621399},{"id":"https://openalex.org/keywords/breast-cancer-cell-lines","display_name":"breast cancer cell lines","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.7127494812011719},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.7026659250259399},{"id":"https://openalex.org/C67082663","wikidata":"https://www.wikidata.org/wiki/Q3523816","display_name":"Molecular medicine","level":4,"score":0.6629810333251953},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6457231044769287},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6293059587478638},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5354136824607849},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.4839487373828888},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45886489748954773},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4563470780849457},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.44343236088752747},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42708563804626465},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4234868884086609},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42131465673446655},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.3966984152793884},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3660004734992981},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3892/ol.2020.12059","doi":"https://doi.org/10.3892/ol.2020.12059","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2020.12059","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2020.12059/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7491119","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7491119","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncol Lett","raw_type":"Text"},{"id":"pmid:32963604","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32963604","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology letters","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3892/ol.2020.12059","doi":"https://doi.org/10.3892/ol.2020.12059","is_oa":true,"landing_page_url":"https://doi.org/10.3892/ol.2020.12059","pdf_url":"https://www.spandidos-publications.com/10.3892/ol.2020.12059/download","source":{"id":"https://openalex.org/S58832373","display_name":"Oncology Letters","issn_l":"1792-1074","issn":["1792-1074","1792-1082"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Letters","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3083366983.pdf","grobid_xml":"https://content.openalex.org/works/W3083366983.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1990400035","https://openalex.org/W1997500225","https://openalex.org/W2000469539","https://openalex.org/W2000859982","https://openalex.org/W2005100930","https://openalex.org/W2024852746","https://openalex.org/W2067669315","https://openalex.org/W2074554263","https://openalex.org/W2086609093","https://openalex.org/W2089582877","https://openalex.org/W2107277218","https://openalex.org/W2114360920","https://openalex.org/W2114387793","https://openalex.org/W2114941442","https://openalex.org/W2139203558","https://openalex.org/W2148345265","https://openalex.org/W2151080109","https://openalex.org/W2326862595","https://openalex.org/W2336550720","https://openalex.org/W2489225975","https://openalex.org/W2560322684","https://openalex.org/W2604193981","https://openalex.org/W2727474048","https://openalex.org/W2741174212","https://openalex.org/W2786427149","https://openalex.org/W2891435420","https://openalex.org/W2894948944","https://openalex.org/W4238991694","https://openalex.org/W4251343507"],"related_works":["https://openalex.org/W4413802016","https://openalex.org/W7097934701","https://openalex.org/W2024694547","https://openalex.org/W4414687112","https://openalex.org/W3196748438","https://openalex.org/W2032474891","https://openalex.org/W2117555991","https://openalex.org/W4225088434","https://openalex.org/W3013921149","https://openalex.org/W3022944528"],"abstract_inverted_index":{"Breast":[0],"cancer":[1],"(BC)":[2],"is":[3,35,53],"the":[4,21,45,67,110,218],"most":[5],"common":[6],"malignant":[7],"tumor":[8,104],"in":[9,44,58,72,81,101,125,236],"females.":[10],"Development":[11],"of":[12,23,48,69,99,135,203,217,233],"novel":[13],"biomarkers":[14],"or":[15,117],"therapeutic":[16],"targets":[17],"may":[18,225,242],"contribute":[19],"toward":[20],"improvement":[22],"a":[24,153,229,244],"patient's":[25],"prognosis.":[26,118],"Marginal":[27],"zone":[28],"B":[29,49],"and":[30,41,86,96,114,142],"B1":[31],"cell\u2011specific":[32],"protein":[33,38,97],"(MZB1)":[34],"an":[36,210],"unfolded":[37],"response\u2011related":[39],"chaperone":[40],"mainly":[42],"exists":[43],"endoplasmic":[46],"reticulum":[47],"lymphocytes,":[50],"although":[51],"little":[52],"known":[54],"regarding":[55],"its":[56],"role":[57],"BC":[59,83,102,130,141,168,178,188,199],"cells.":[60],"The":[61,215],"present":[62,219],"study":[63,220],"aimed":[64],"to":[65,108],"investigate":[66],"significance":[68],"MZB1":[70,77,100,119,136,207,223,241],"expression":[71,79,98,113,121,138,224],"BC.":[73,234],"To":[74],"begin":[75],"with,":[76],"mRNA":[78,95,120,137],"levels":[80,122,139],"13":[82],"cell":[84,90,131],"lines":[85,91],"two":[87],"non\u2011cancerous":[88,143],"mammary":[89],"were":[92,123,145],"evaluated.":[93],"Next,":[94],"patient":[103],"specimens":[105,144],"was":[106,209],"evaluated":[107],"assess":[109],"association":[111],"between":[112,140],"clinicopathological":[115],"factors":[116],"detectable":[124],"four":[126],"estrogen":[127],"receptor":[128],"(ER)\u2011positive":[129],"lines.":[132],"When":[133],"ratios":[134],"evaluated,":[146],"patients":[147,157,165,175,181,185,196,237],"with":[148,158,166,174,176,182,186,197,228,238],"stage":[149,159,232],"III":[150],"disease":[151,161],"exhibited":[152],"higher":[154],"ratio":[155],"than":[156,195],"0/I/II":[160],"(P=0.009).":[162],"Using":[163],"immunohistochemistry,":[164],"ER\u2011positive":[167,183,239],"more":[169,230],"frequently":[170],"expressed":[171],"MZB1,":[172],"compared":[173],"ER\u2011negative":[177],"(P=0.003).":[179],"In":[180],"BC,":[184,240],"MZB1\u2011positive":[187],"experienced":[189],"shorter":[190],"disease\u2011free":[191],"survival":[192],"(DFS)":[193],"times":[194],"negative":[198],"(P=0.026).":[200],"Multivariate":[201],"analysis":[202],"DFS":[204],"demonstrated":[205],"that":[206,222],"positivity":[208],"independent":[211],"prognostic":[212,246],"factor":[213],"(P=0.022).":[214],"results":[216],"suggested":[221],"be":[226,243],"associated":[227],"advanced":[231],"Furthermore,":[235],"potential":[245],"marker.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2020-09-11T00:00:00"}