{"id":"https://openalex.org/W3083335348","doi":"https://doi.org/10.2319/022420-125.1","title":"Effects of xylitol impregnated toothbrushes on periodontal status and microbial flora in orthodontic patients","display_name":"Effects of xylitol impregnated toothbrushes on periodontal status and microbial flora in orthodontic patients","publication_year":2020,"publication_date":"2020-09-03","ids":{"openalex":"https://openalex.org/W3083335348","doi":"https://doi.org/10.2319/022420-125.1","mag":"3083335348","pmid":"https://pubmed.ncbi.nlm.nih.gov/33378517","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8028427"},"language":"en","primary_location":{"id":"doi:10.2319/022420-125.1","doi":"https://doi.org/10.2319/022420-125.1","is_oa":true,"landing_page_url":"https://doi.org/10.2319/022420-125.1","pdf_url":null,"source":{"id":"https://openalex.org/S177636448","display_name":"The Angle Orthodontist","issn_l":"0003-3219","issn":["0003-3219","1945-7103"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316334","host_organization_name":"E.H Angle Education and Research Foundation","host_organization_lineage":["https://openalex.org/P4310316334"],"host_organization_lineage_names":["E.H Angle Education and Research Foundation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Angle Orthodontist","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.2319/022420-125.1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004036391","display_name":"Selin Ko\u015far","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Selin Ko\u015far","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078676425","display_name":"Serpil \u00c7okako\u011flu","orcid":"https://orcid.org/0000-0002-1240-6951","observed_orcids":["https://orcid.org/0000-0002-1240-6951"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Serpil \u00c7okako\u011flu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5076553958","display_name":"\u0130lknur Kaleli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u0130lknur Kaleli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5078676425"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6838,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.67092837,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"90","issue":"6","first_page":"837","last_page":"843"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12439","display_name":"Dental Research and COVID-19","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xylitol","display_name":"xylitol","score":0.9340000152587891},{"id":"https://openalex.org/keywords/toothbrushes","display_name":"toothbrushes","score":0.8379999995231628},{"id":"https://openalex.org/keywords/orthodontic-patients","display_name":"orthodontic patients","score":0.9279999732971191},{"id":"https://openalex.org/keywords/periodontal-health","display_name":"periodontal health","score":0.8420000076293945},{"id":"https://openalex.org/keywords/oral-microbiota","display_name":"oral microbiota","score":0.6079999804496765},{"id":"https://openalex.org/keywords/dental-plaque","display_name":"dental plaque","score":0.7300000190734863},{"id":"https://openalex.org/keywords/gingivitis","display_name":"gingivitis","score":0.6859999895095825},{"id":"https://openalex.org/keywords/bleeding-on-probing","display_name":"bleeding on probing","score":0.8610000014305115},{"id":"https://openalex.org/keywords/streptococcus-mutans","display_name":"Streptococcus mutans","score":0.9760000109672546},{"id":"https://openalex.org/keywords/poor-oral-hygiene","display_name":"poor oral hygiene","score":0.7540000081062317},{"id":"https://openalex.org/keywords/saliva-bacteria","display_name":"saliva bacteria","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C2776031079","wikidata":"https://www.wikidata.org/wiki/Q212093","display_name":"Xylitol","level":3,"score":0.8969326019287109},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.7393434047698975},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7149980068206787},{"id":"https://openalex.org/C2777968807","wikidata":"https://www.wikidata.org/wiki/Q4925923","display_name":"Bleeding on probing","level":3,"score":0.5770555138587952},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.5382651090621948},{"id":"https://openalex.org/C515851188","wikidata":"https://www.wikidata.org/wiki/Q13445028","display_name":"Oral hygiene","level":2,"score":0.48251792788505554},{"id":"https://openalex.org/C2779914569","wikidata":"https://www.wikidata.org/wiki/Q143504","display_name":"Dental plaque","level":2,"score":0.48205170035362244},{"id":"https://openalex.org/C2780791200","wikidata":"https://www.wikidata.org/wiki/Q673083","display_name":"Gingivitis","level":2,"score":0.4577315151691437},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.4501856565475464},{"id":"https://openalex.org/C58747440","wikidata":"https://www.wikidata.org/wiki/Q1059860","display_name":"Gingival and periodontal pocket","level":3,"score":0.43843603134155273},{"id":"https://openalex.org/C2777234453","wikidata":"https://www.wikidata.org/wiki/Q2033092","display_name":"Flora (microbiology)","level":3,"score":0.43213337659835815},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.15740478038787842},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15578454732894897},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09818124771118164},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08182457089424133},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06646513938903809},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003774","descriptor_name":"Dental Plaque Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010512","descriptor_name":"Periodontal Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014099","descriptor_name":"Toothbrushing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014993","descriptor_name":"Xylitol","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016382","descriptor_name":"Orthodontic Appliance Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.2319/022420-125.1","doi":"https://doi.org/10.2319/022420-125.1","is_oa":true,"landing_page_url":"https://doi.org/10.2319/022420-125.1","pdf_url":null,"source":{"id":"https://openalex.org/S177636448","display_name":"The Angle Orthodontist","issn_l":"0003-3219","issn":["0003-3219","1945-7103"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316334","host_organization_name":"E.H Angle Education and Research Foundation","host_organization_lineage":["https://openalex.org/P4310316334"],"host_organization_lineage_names":["E.H Angle Education and Research Foundation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Angle Orthodontist","raw_type":"journal-article"},{"id":"pmid:33378517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33378517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Angle orthodontist","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8028427","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8028427/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angle Orthod","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.2319/022420-125.1","doi":"https://doi.org/10.2319/022420-125.1","is_oa":true,"landing_page_url":"https://doi.org/10.2319/022420-125.1","pdf_url":null,"source":{"id":"https://openalex.org/S177636448","display_name":"The Angle Orthodontist","issn_l":"0003-3219","issn":["0003-3219","1945-7103"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316334","host_organization_name":"E.H Angle Education and Research Foundation","host_organization_lineage":["https://openalex.org/P4310316334"],"host_organization_lineage_names":["E.H Angle Education and Research Foundation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Angle Orthodontist","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W40426444","https://openalex.org/W145936716","https://openalex.org/W1533689043","https://openalex.org/W1896227688","https://openalex.org/W1989275842","https://openalex.org/W2014925066","https://openalex.org/W2017583003","https://openalex.org/W2021792184","https://openalex.org/W2042966425","https://openalex.org/W2043300924","https://openalex.org/W2053988129","https://openalex.org/W2054068403","https://openalex.org/W2057364120","https://openalex.org/W2058041864","https://openalex.org/W2060617961","https://openalex.org/W2066616037","https://openalex.org/W2107228383","https://openalex.org/W2113009278","https://openalex.org/W2113332511","https://openalex.org/W2114691160","https://openalex.org/W2117172004","https://openalex.org/W2167402110","https://openalex.org/W2236021849","https://openalex.org/W2337898958","https://openalex.org/W2400716300","https://openalex.org/W2488473558","https://openalex.org/W2810676782"],"related_works":["https://openalex.org/W4293282369","https://openalex.org/W1896227688","https://openalex.org/W4407908343","https://openalex.org/W2019880567","https://openalex.org/W7212305255","https://openalex.org/W3115756718","https://openalex.org/W4391667720","https://openalex.org/W1823666609","https://openalex.org/W2279413648","https://openalex.org/W4324385623"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"investigate":[2],"whether":[3],"the":[4,46,132,184,213,230,245],"use":[5,224],"of":[6,225],"xylitol-impregnated":[7],"toothbrushes":[8,44,227],"affects":[9],"periodontal":[10,52,74,108,239],"condition":[11],"and":[12,45,54,66,76,90,103,116,126,144,154,159,189,195,233,240],"microbial":[13,164,216,241],"flora":[14,217],"in":[15,121,131,139,183,192,200,215],"orthodontic":[16],"patients":[17,26],"with":[18,27,83,100],"poor":[19],"oral":[20],"hygiene.":[21],"MATERIALS":[22],"AND":[23],"METHODS:":[24],"Forty-four":[25],"baseline":[28,60],"mean":[29],"Turesky":[30],"plaque":[31,84],"index":[32,85,88],"scores":[33,128,137],"\u22651.5":[34],"were":[35,57,97,167,198,210],"randomly":[36],"divided":[37],"into":[38],"two":[39],"groups.":[40,123],"Half":[41],"received":[42],"xylitol-containing":[43,226],"other":[47],"half,":[48],"xylitol-free":[49],"toothbrushes.":[50],"The":[51,124],"measurements":[53],"saliva":[55],"samples":[56],"taken":[58],"at":[59,156,218],"(T0),":[61],"1":[62],"month":[63],"later":[64],"(T1),":[65],"3":[67],"months":[68],"after":[69],"brushing":[70],"(T2)":[71],"to":[72,114,119,176,205,244],"evaluate":[73],"health":[75],"microflora":[77],"changes.":[78],"Periodontal":[79],"status":[80],"was":[81],"assessed":[82],"(PI),":[86],"gingival":[87],"(GI),":[89],"bleeding":[91],"on":[92,238],"probing":[93],"(BOP)":[94],"scores.":[95],"Data":[96],"statistically":[98,169],"analyzed":[99],"Mann-Whitney":[101],"U":[102],"Friedman":[104],"tests.":[105],"RESULTS:":[106],"All":[107],"parameters":[109,242],"significantly":[110,130,181],"decreased":[111,182],"from":[112,117,174,203],"T0":[113,118,175,204],"T1":[115,143,188],"T2":[120,160],"both":[122,140,201],"PI":[125],"GI":[127,155],"reduced":[129,138],"control":[133,246],"group,":[134],"while":[135],"BOP":[136],"groups":[141,173,202,214],"between":[142,187,212],"T2.":[145,190,206],"Intergroup":[146],"comparisons":[147],"showed":[148,228],"significant":[149,170,199,208],"differences":[150,171,209],"for":[151],"BOP,":[152],"PI,":[153],"T0,":[157],"T1,":[158],"times,":[161],"respectively.":[162],"For":[163],"parameters,":[165],"there":[166],"no":[168,235],"within":[172],"T1.":[177],"Total":[178],"bacterial":[179],"counts":[180],"xylitol":[185],"group":[186],"Decreases":[191],"Streptococcus":[193],"mutans":[194],"total":[196],"bacteria":[197],"No":[207],"found":[211],"any":[219],"time.":[220],"CONCLUSIONS:":[221],"A":[222],"3-month":[223],"almost":[229],"same":[231],"changes":[232],"provided":[234],"positive":[236],"effects":[237],"compared":[243],"group.":[247]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2020-09-11T00:00:00"}